group lead group lead

Lead: Professor Aedín Cassidy

Activities and ethos of the group Activities and ethos of the group

89% of the Department’s research was rated as world leading/internationally excellent in the Research Excellence Framework (REF2014) and our research publications were rated 6th in the UK (Sub-panel 6, REF2014). Our interdisciplinary research strategy investigates the impact of key dietary components on major age-related chronic diseases, in particular cardiovascular and metabolic health, and cognitive health and decline, and can be broadly divided into 3 main research themes:

• Flavonoids and other polyphenols;

• Dietary fats;

• Nutrigenetics

A unique aspect of our research is our integrated approach. We use a combination of cell/animal models, carefully phenotyped population based cohorts (Harvard cohorts (Nurses’ Health Study, Health Professionals Follow-Up Study), Framingham, EU/National population based studies) and intervention trials in healthy and patient groups, to investigate food bioactive absorption and metabolism, impact on risk biomarkers and incident disease, and physiological and molecular mechanisms of action. We have a growing interest in the impact of the microbiome and flavonoid metabolism on cardiometabolic health. 

key areas of research key areas of research

  • Flavonoids, their metabolites and cardiometabolic health
  • n-3 fatty acids and the cardiometabolic phenotype
  • Diet and age-related cognitive decline
  • Flavonoids, the microbiome and health
  • Biomarkers of dietary exposure
  • Diet-gene interactions 
  • APOE genotype, health and response to dietary change

researchers researchers

Researchers:

Primary affiliation

Aedin Cassidy, Chair in Nutritional Biochemistry

Anne Marie Minihane, Professor of Nutrigenetics

Michael Muller, Professor of Nutrigenetics

Narelle Berry, Lecturer in Vascular Physiology

Peter Curtis, Senior Research Fellow

Amy Jennings, Senior Research Fellow

Rafe Bundy, Post-doctoral Scientist

Rachel Gillings, Research Assistant

Rasha Saleh, Research Associate

Caoimhe Flynn, PhD student

Laura Haag, PhD student

Matthew Pontifex, PhD student

Secondary affiliation

Yongping Bao

Ian Clark

Sue Fairweather-Tait

Alastair Forbes

William Fraser

Lee Hooper

Inez Schoenmakers

Alexander MacGregor

John Potter

Ailsa Welch

external collaborators external collaborators

  • Harvard T. H. Chan School of Public Health: Dietary flavonoids and cardiometabolic health
  • Harvard Medical School: Moderate alcohol and cardiovascular health (MACH15)- a worldwide clinical study,
  • TUFTS: Dietary flavonoids and cardiometabolic health
  • University of Kiel:APOE genotype and inflammation, POPGEN (flavonoids)
  • Nutrition and Cognition, University of Illinois
  • Lipid metabolism and molecular nutrition, University of Waginingen,

In the UK we have collaborations with colleagues from:
King's College London, University of Cambridge, University of Southampton, Newcastle University, University of Reading

other information other information

Our main research funders are the BBSRC, USDA/USHBC, NIH/NIAAA, EU, Alz Soc ARUK, and several industrial collaborators including Abbott Healthcare and Unilever Best Foods