Understanding the evolution of calcium signal decoding mechanisms in plants (MILLER_U27DTP)
Key details
- Application Deadline
- 30 November 2026 23:59 UK Time
- Location
- UEA
- Funding Type
- Competition Funded (Home and International)
- Start Date
- 1 October 2027
- Mode of Study
- Full-time
- Programme Type
- PhD
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Project Description
"Plants need to respond to the environment in order to adapt and grow. Plants often modify the concentration of calcium ions in their cells in response to different environmental stimuli and stresses [1]. These changes in cellular calcium concentration trigger many downstream responses, including re-programming of gene expression. Calcium signalling pathways are therefore essential for plants to respond and adapt to environmental stimuli and stresses.
Flowering plants, such as the model plant Arabidopsis thaliana, have extensive networks of proteins associated with calcium signalling pathways, and traditional genetic studies have identified mutants in components of these pathways. However, genetic redundancy is often observed and this has hindered further study of these signalling pathways. Recent genomic analyses have revealed that the gene families encoding components of calcium signalling pathways are considerably smaller in other model plant species, including in the liverwort Marchantia polymorpha [3]. The study of these pathways in M. polymorpha will therefore offer unique insights and understandings into calcium signalling pathways in plants, and may identify new potential targets that could be manipulated to improve stress tolerance in crop species.
This PhD project will undertake a multi-disciplinary approach combining molecular genetics, cell biology and biochemistry to dissect calcium signalling and decoding mechanisms in the liverwort Marchantia polymorpha.
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Entry Requirements
At least UK equivalence Bachelors (Honours) 2:1. English Language requirement (Faculty of Science equivalent: IELTS 6.5 overall, 6 in each category).
Funding
This project is awarded with a 4-year Norwich Research Park Biosciences Doctoral Training Partnership PhD DTP studentship. The studentship includes payment of tuition fees (directly to the University), a stipend to cover living expenses (2026/27 stipend rate: £21,805, and a Research Training Support Grant of £5,000pa for each year of the studentship.
References
Dong et al. (2022) J Integrative Plant Biology 64:287-300 Bender et al. (2018) Biochemical J 475:207-23 Tansley et al. (2023) New Phytologist 237:2210-2223 Feike et al. (2019) Plant Biotech J. 17:2234-2245