Our study teams are investigating the following projects surrounding medication use and dementia.
Anticholinergics, Benzodiazepines, Cognition and Dementia
The ABCD (Anticholinergics, Benzodiazepines, Cognition and Dementia) study aims to understand the effect of anticholinergic medication, benzodiazepine and Z-drug use on cognitive decline and dementia incidence in older people.
This three-year study is advancing our knowledge of the effects of specific classes of commonly used medicines on cognitive decline and dementia incidence in the older population. We are using routine data collected through the Clinical Practice Research Datalink (CPRD) and data from two cohort studies, the MRC Cognitive Function and Ageing Study (MRC CFAS) and The Irish Longitudinal Study on Ageing (TILDA).
This study is funded by the Alzheimer's Society. Further details of the study design are described on the ABCD Research Plan page.