Co-enrolment

Prepare-ABC

The exercise intervention is intended in addition, rather than to replace any current treatments, therapies or surgery. We are therefore able to permit patients who are currently participating or have previously participated in other trials, providing they meet the eligibility criteria of Prepare-ABC and that co-enrolment has been agreed by both trial teams.

Please see below for a current list of trials where co-enrolment has been agreed:

  • ADD-Aspirin: "A phase III, double-blind, placebo-controlled, randomised trial assessing the effects of aspirin on disease recurrence and survival after primary therapy in common non-metastatic solid tumours" EudraCT: 2013-004393-28
  • ARISTOTLE: "A phase III trial comparing standard versus movel chemoradiation treatment (CRT) as pre-operative treatment for magnetic resonance imaging (MRI)-defined locally advanced rectal cancer" EudraCT 2008-005782-59
  • CHHIP: "Conventional or hypofractionated high dose intensity modulated radiotherapy for prostate cancer" ISCRTN 97182923
  • CIPHER: "A prospective observational study, over an initial 2 year recruitment period, that aims to establish the incidence of symptomatic and radiological parastomal hernia during a minimum of 2 years follow up and to evaluate the effects of key technical surgical steps during index stoma formation on the risk of subsequent parastomal hernia formation" ISRCTN 17573805
  • DALES: "Drug Allergy Labels in the Elective Surgical population" IRAS ID 232512
  • EPOCH: "An international Phase III clinical trial evaluating yttrium-90 trans-arterial radioembolization (TheraSphere®) in patients with metastatic colorectal carcinoma (mCRC) of the liver who have failed first-line chemotherapy" NCT01483027
  • LABSS: "The Lothian Bowel Symptoms Study"
  • MINSTREL: "MRI in staging rectal polyp planes" NCT02532803
  • PREVENTT: "A randomised double-blind controlled phase 3 study to compare the efficacy and safety of intravenous ferric carboxymaltose with placebo in patients with anaemia undergoing major open abdominal surgery" EudraCT: 2012-002786-35
  • PRISM: "A pragmatic randomised controlled trial of continuous positive airway pressure (CPAP) to prevent respirator complications and improve survival following major abdominal surgery" REC reference: 15/LO/1595, ISRCTN56012545
  • PQUIP: "Perioperative Quality Improvement Programme - A multidisciplinary initiative supporting local quality improvement to benefit patients undergoing major surgery" CPMS 32256
  • Quantifying Disease Burden in Patients with Cancer using Tumour-specific Genomic Rearrangements (funded by the Wellcome Trust).
  • SAILOR: "A multicentre randomised feasibility trial evaluating early surgery alone in low rectal cancer" EudraCT 2014-001373-13
  • SCOTTY: "Sequencing of Colon Trios in The Young" IRAS ID 200475
  • SOCCS3: "A study looking at genes of people in Scotland who have developed bowel cancer, to see if the information can identify other people at risk of developing the disease and fully understand the genetic basis of bowel cancer" REC reference: 11/SS/0109
  • TRIGGER: "A multi-centre, feasibility, cluster randomised controlled trial comparing restrictive versus liberal blood transfusion strategies in adult patients admitted with acute upper gastrointestinal bleeding" NB Co-enrolment allowed in control arm patients only. ISRCTN85757829
  • 100,000 Genomes Project: "The project will sequence 100,000 genomes from around 70,000 people. Participants are NHS patients with a rare disease, plus their families, and patients with cancer"
  • TRACC: "Tracking mutations in cell free tumour DNA to predict Relapse in eArly Colorectal Cancer" NCT00827671
  • RECREATE: reducing sedentary behaviour following a stroke (University of Leeds)
  • Sumit-d: "Support through mobile messaging and digital health technology for diabetes." ISRCTN13404264
  • SCOVIDS: Scottish Vitamin D.
  • Terasphere: "An open-label, prospective, multicentre, randomised, phase III clinical trial evaluating yttrium-90 transarterial radioembolization with TheraSphere in patients with metastatic colorectal carcinoma (mCRC) of the liver who have failed first-line chemotherapy." ISCRTN13404264.NCT01483027.
  • EPIC-Norfolk: "The European Prospective Investigation of Cancer (EPIC)."
  • NHS Highland feasibility study: "A physical activity intervention to improve the quality of life of patients with a stoma: a feasibility study."
  • University of Birmingham feasibility study: "Measuring actue sarcopenia in older colorectal surgery patients: a pilot observational study." Ethics ERN ref ERN_17_0024. IRAS210641
  • IBD-BioResource: "The UK Inflammatory Bowel Disease BioResource: Progressing from Genetics to Function and Clinical Translation in Crohn's Disease and Ulcerative Colitis." IRAS 173561
  • STAMPEDE: "Systemic Therapy in Advancing or Metastatic Prostate Cancer: Evaluation of Drug Efficacy." ISRCTN78818544.