A selection of latest publications A selection of latest publications

The latest research publications and papers from within the school of Pharmacy.

Smith R, Weekes H, Morgan, L, Parkes M, Lee JC.
Tacrolimus suppositories: a safe and effective treatment for treatment-refractory proctitis (A-1951).
14th ECCO, Copenhagen, Denmark.  March 2019

Bidula, Stefan M., Cromer, Brett A., Walpole, Samuel., Angulo, Jesus, Stokes, Leanne.
Mapping a novel positive allosteric modulator binding site in the central vestibule region of human P2X7. (2019)
Scientific Reports volume 9, Article number: 3231

González-Paredes A, Sitia L, Ruyra A, Morris CJ, Wheeler GN, McArthur M, Gasco P.
Solid lipid nanoparticles for the delivery of anti-microbial oligonucleotides. (2019)
Eur J Pharm Biopharm. 134:166-177.
DOI: 10.1016/j.ejpb.2018.11.017. Epub 2018 Nov 20.

Dhuna, Kshitija., Felgate, Matthew., Bidula, Stefan M., Walpole, Samuel., Bibic, Lucka., Cromer, Brett A., Angulo, Jesus., Sanderson, Julie., Stebbing, Martin J and Stokes, Leanne.
Ginsenosides act as positive modulators of P2X4 receptors. 2018
Molecular Pharmacology, mol.118.113696;
DOI: 10.1124/mol.118.113696

Morgan L.
Problematic Polypharmacy: when to stop prescribing>. Nov 2018.
Nursing and Residential Care.  20:11

Liso, M., De Santis, S., Scarano, A., Verna, G., Dicarlo, M., Galleggiante, V., Campiglia, P.,  Mastronardi, M., Lippolis, A., Vacca, M., Sobolewski, A., Serino, G., Butelli, E., De Angelis, M.,
Martin, C., Santino, A. & Chieppa, M.
A Bronze-Tomato Enriched Diet Affects the Intestinal Microbiome under Homeostatic and Inflammatory Conditions. (2018)
In: Nutrients. 10, 12, 1862
DOI: 10.3390/nu10121862

Carro, L.
Protein–protein interactions in bacteria: a promising and challenging avenue towards the discovery of new antibiotics. (2018)
In : Beilstein Journal of Organic Chemistry. 14, p. 2881-2896
DOI: 10.3762/bjoc

Katangwe, T., Bhattacharya, D. & Twigg, M. (2018)
A systematic review exploring characteristics of lifestyle modification interventions in newly diagnosed type 2 diabetes for delivery in community pharmacy.
(Accepted/In press) In : International Journal of Pharmacy Practice

Redox Modulation at Work: Natural Phytoprotective Polysulfanes From Alliums Based on Redox-Active Sulfur. (2018)
Anwar, A., Gould, E., Tinson, R., Iqbal, J. & Hamilton, C.
In : Current Pharmacology Reports. 4, 5, p. 397–407
DOI: 10.1007/s40495-018-0153-2

Nartowski, K., Malhotra, D., Hawarden, L., Fabian, L. & Khimyak, Y.
Nanocrystallization of Rare Tolbutamide Form V in Mesoporous MCM-41 Silica. (2018)
In : Molecular Pharmaceutics.
DOI: 10.1021/acs.molpharmaceut.8b00575

Kay, K. L., Hamilton, C. J. & Le Brun, N. E.
Mass spectrometric studies of Cu(I)-binding to the Nterminal domains of B. subtilis CopA and influence of bacillithiol. (2018)
In : Journal of Inorganic Biochemistry. 190, p. 24-30
DOI: 10.1016/j.jinorgbio.2018.10.004

Easthall, C., Taylor, N. & Bhattacharya, D.
Barriers to medication adherence in patients prescribed medicines for the prevention of cardiovascular disease: a conceptual framework. (2018)
In : International Journal of Pharmacy Practice.
DOI: 10.1111/ijpp.12491

Alhijjaj, M., Belton, P., Fabian, L., Wellner, N., Reading, M. & Qi, S.
A novel thermal imaging method for rapid screening of drug-polymer miscibility for solid dispersion based formulation development. (2018)
In : Molecular Pharmaceutics.
DOI: 10.1021/acs.molpharmaceut.8b00798

Abdelhamid, M. A. S., Gates, A. J. & Waller, Z. A. E.
Destabilization of i-Motif DNA at Neutral pH by GQuadruplex Ligands. (2018)
DOI: 10.1021/acs.biochem.8b00968

Wright, D., Scott, S., Buck, J. & Bhattacharya, D.
Roles of nurses in supporting proactive deprescribing. (2018)
(Accepted/In press) In: Nursing Standard.

R., Rejzek, M., Wegmann, U., Le Gall, G., Kavanaugh, D. W., Colquhoun, I., Frese, S., MacKenzie, D. A., Walter, J., Angulo, J., Field, R. & Juge, N.
Serine-Rich Repeat Protein adhesins from Lactobacillus reuteri display strain specific glycosylation profiles Latousakis, D., Nepravishta.(2018)
(Accepted/In press) In : Glycobiology.
DOI: 10.1093/glycob/cwy100

Brown, T. J., Twigg, M., Taylor, N., Easthall, C., Hartt, J., Budd, T., Li, Z., Dima, A. & Bhattacharya, D.
Final Report for the IMAB-Q study: Validation and Feasibility Testing of a Novel Questionnaire to Identify Barriers to Medication Adherence. (2018)
Pharmacy Research UK.

Scott, S., Clark, A., May, H.& Bhattacharya, D.
Validation and Feasibility of the Medication Acceptability Questionnaire to Investigate Tablet and Liquid Alendronic Acid with Older Hospital Patients. (2018)
Pharmacy. 6, 11 p., 84
DOI: 10.3390/pharmacy6030084.

Craske, M., Wright, D., Blacklock, J., Matthews, H., Dean, T., Farrow, T., Daly, C. & Duell, P.
Testing annual asthma reviews for those who fail to attend: proof-of-concept study. (2018)
The Pharmaceutical Journal. 8, 10, p. 243-249 7 p.

Calabrese, V., da Silva, M. A., Schmitt, J., Muñoz- Garcia, J. C., Gabrielli, V., Scott, J. L., Angulo, J., Khimyak, Y. Z. & Edler, K. J.
Surfactant controlled zwitterionic cellulose nanofibril dispersions. (2018)
Soft Matter.
DOI: 10.1039/C8SM00752G

Abdelhamid, M. A. S., Fábián, L., MacDonald, C. J., Cheesman, M. R., Gates, A. J. & Waller, Z. A. E.
Redox-dependent control of i-Motif DNA structure using copper cations. (2018)
Nucleic Acids Research.
DOI: 10.1093/nar/gky390

Nasereddin, J. M., Wellner, N., Alhijjaj, M., Belton, P., Qi, S.
Development of a Simple Mechanical Screening Method for Predicting the Feedability of a Pharmaceutical FDM 3D Printing Filament. (2018)
Pharmaceutical Research 35 (8) article no. 151
DOI: 10.1007/s11095-018-2432-3

Twigg M, Wright D, Barton G, Kirkdale CL, Thornley T.
The pharmacy care plan service: Service evaluation and estimate of cost-effectiveness. (2018)
Research in Social & Administrative Pharmacy. PII: S1551-7411(17)30838-0 
DOI: 10.1016/j.sapharm.2018.03.062

Abdelhamid, MAS, Fábián, L, MacDonald, CJ, Cheesman, MR, Gates, Zoë AE Waller.
Redox-dependent control of i-Motif DNA structure using copper cations. (2018)
Nucleic Acids Research, gky390,
DOI: 10.1093/nar/gky390

Marín-Barba M, Gavilán H, Gutiérrez L, Lozano-Velasco E, Rodríguez-Ramiro I, Wheeler GN, Morris CJ, Morales MP, Ruiz A.
Unravelling the mechanisms that determine the uptake and metabolism of magnetic single and multicore nanoparticles in a Xenopus laevis model (2018).
Nanoscale. Jan 3;10(2):690-704.
DOI: 10.1039/C7NR06020C.

Al-Jabr H, Twigg MJ, Scott S, Desborough JA.
Patient feedback questionnaires to enhance consultation skills of healthcare professionals:  A systematic review. (2018)
Patient Educ Couns.
DOI: 10.1016/j.pec.2018.03.016

Tipduangta P, Takieddin K, Fábián L, Belton P, Qi S
Towards controlling the crystallisation behaviour of fenofibrate melt: triggers of crystallisation and polymorphic transformation. (2018)
RSC Adv., 8, 13513-13525
DOI: 10.1039/C8RA01182F

Matthews, SE, S Cecioni, S, O'Brien, J E, MacDonald, C J, Hughes, D L, Jones, G A, Ashworth, S H, Vidal, S
Fixing the Conformation of Calix[4]arenes: When Are Three Carbons Not Enough? (2018)
Chem. Eur. J, 24, 17, 4436-4444
DOI: 10.1002/chem.201705955

Mills SC, Howell L, Beekman A, Stokes L, Mueller A.
Rac1 plays a role in CXCL12 but not CCL3-induced chemotaxis and Rac1 GEF inhibitor NSC23766 has off target effects on CXCR4. (2018)
Cell Signal. Jan;42:88-96.
DOI: 10.1016/j.cellsig.2017.10.006. Epub 2017 Oct 16.