A selection of latest publications A selection of latest publications

The latest research publications and papers from within the school of Pharmacy.

Nasereddin, J. M., Wellner, N., Alhijjaj, M., Belton, P., Qi, S.
Development of a Simple Mechanical Screening Method for Predicting the Feedability of a Pharmaceutical FDM 3D Printing Filament. (2018)
Pharmaceutical Research 35 (8) article no. 151
DOI: 10.1007/s11095-018-2432-3

Twigg M, Wright D, Barton G, Kirkdale CL, Thornley T.
The pharmacy care plan service: Service evaluation and estimate of cost-effectiveness. (2018)
Research in Social & Administrative Pharmacy. PII: S1551-7411(17)30838-0 
DOI: 10.1016/j.sapharm.2018.03.062

Redox-dependent control of i-Motif DNA structure using copper cations. (2018)
Abdelhamid, MAS, Fábián, L, MacDonald, CJ, Cheesman, MR, Gates, Zoë AE Waller.
Nucleic Acids Research, gky390,
DOI: 10.1093/nar/gky390

Unravelling the mechanisms that determine the uptake and metabolism of magnetic single and multicore nanoparticles in a Xenopus laevis model (2018).
Marín-Barba M, Gavilán H, Gutiérrez L, Lozano-Velasco E, Rodríguez-Ramiro I, Wheeler GN, Morris CJ, Morales MP, Ruiz A.
Nanoscale. Jan 3;10(2):690-704.
DOI: 10.1039/C7NR06020C.

Patient feedback questionnaires to enhance consultation skills of healthcare professionals:  A systematic review.
Al-Jabr H, Twigg MJ, Scott S, Desborough JA.
Patient Educ Couns (2018).
DOI: 10.1016/j.pec.2018.03.016

Towards controlling the crystallisation behaviour of fenofibrate melt: triggers of crystallisation and polymorphic transformation.
Tipduangta P, Takieddin K, Fábián L, Belton P, Qi S (2018)
RSC Adv., 8, 13513-13525
DOI: 10.1039/C8RA01182F

Fixing the Conformation of Calix[4]arenes: When Are Three Carbons Not Enough?
Matthews, SE, S Cecioni, S, O'Brien, J E, MacDonald, C J, Hughes, D L, Jones, G A, Ashworth, S H, Vidal, S (2018)
Chem. Eur. J, 24, 17, 4436-4444
DOI: 10.1002/chem.201705955

Rac1 plays a role in CXCL12 but not CCL3-induced chemotaxis and Rac1 GEF inhibitor NSC23766 has off target effects on CXCR4.
Mills SC, Howell L, Beekman A, Stokes L, Mueller A. (2018)
Cell Signal. Jan;42:88-96.
DOI: 10.1016/j.cellsig.2017.10.006. Epub 2017 Oct 16.

Hung MY, Wright D, Needle R.
Identification of the benefits, enablers and barriers to integrating junior pharmacists into the ward team within one UK-based hospital. (2017)
Integrated Pharmacy Research and Practice; 6:181-90

Defining the role of the pharmacy technician and identifying their future role in medicines optimisation.
Boughen M, Sutton J, Fenn T, Wright D.* (2017)
Pharmacy. Jul 15;5(3). pii: E40.
DOI: 10.3390/pharmacy5030040.

Development of a core outcome set for effectiveness trials aimed at optimising prescribing in older adults in care homes.
Millar AN, Daffu-O'Reilly A, Hughes CM, Alldred DP, Barton G, Bond CM, Desborough JA, Myint PK, Holland R, Poland FM, Wright D; CHIPPS Team, University of East Anglia. (2017)
Trials. Apr 12;18(1):175.
DOI: 10.1186/s13063-017-1915-6.

Wright D, Begent D, Crawford H, Foundling Miah M, Griffith R, Merriman H.
Medication management of adults with swallowing difficulties.
Guidelines November 2017; Medendium Group Publishing Ltd.

Insight into Flufenamic Acid Cocrystal Dissolution in the Presence of a Polymer in Solution: from Single Crystal to Powder Dissolution.
Minshan Guo, Ke Wang, Ning Qiao, László Fábián, Ghazala Sadiq⊥, and Mingzhong Li (2017)
Mol. Pharmaceutics, 2017, 14 (12), pp 4583–4596
DOI: 10.1021/acs.molpharmaceut.7b00712

Marín-Menéndez, Alejandro; Montis, Costanza; Díaz-Calvo, Teresa; Carta, Davide; Hatzixanthis, Kostas; Morris, Christopher J; McArthur,Michael; Berti, Debora.
Antimicrobial Nanoplexes meet Model Bacterial Membranes: the key role of Cardiolipin. (2017).
Scientific Reports 7, Article number: 41242
DOI:10.1038/srep41242

Cadman, Brit; Wright, David; Bale, Amanda; Barton, Garry; Desborough, James; Hammad, Eman A; Holland, Richard; Howe, Helen; Nunney, Ian; Irvine, Lisa.
Pharmacist provided medicines reconciliation within 24 hours of admission and on discharge: a randomised controlled pilot study. (2017)
BMJ Open, 7:e013647
DOI: 10.1136/bmjopen-2016-013647

Endocytic Uptake, Transport and Macromolecular Interactions of Anionic PAMAM Dendrimers within Lung Tissue (2017).
Morris CJ, Aljayyoussi G, Mansour O, Griffiths P, Gumbleton M.
Pharm Res. Dec;34(12):2517-2531.
DOI: 10.1007/s11095-017-2190-7

Cationic liposomal vectors incorporating a bolaamphiphile for oligonucleotide antimicrobials (2017).
Mamusa M, Sitia L, Barbero F, Ruyra A, Calvo TD, Montis C, Gonzalez-Paredes A, Wheeler GN, Morris CJ, McArthur M, Berti D.
Biochim Biophys Acta. Oct;1859(10):1767-1777.
DOI: 10.1016/j.bbamem.2017.06.006.

Twigg MJ, Wright D, Kirkdale CL, Desborough JA, Thornley T.
The UK Pharmacy Care Plan service: Description, recruitment and initial views on a new community pharmacy intervention. (2017)
PLoS ONE 12(4): e0174500.
DOI: 10.1371/journal.pone.0174500

Alhijjaj M, Belton P, Qi S.
An investigation into the use of polymer blends to improve the printability of and regulate drug release from pharmaceutical solid dispersions prepared via fused deposition modeling (FDM) 3D printing. (2016)
Eur. J. Pharm & Biopharm., 108, pp 111–125,
DOI: 10.1016/j.ejpb.2016.08.016

Bowman, Kate A.; Aarstad, Olav Andreas; Nakamura, Marcela; Stokke, Bjørn Torger; Skjåk-bræk, Gudmund; Round, Andrew N. (Lead Author).
Single molecule investigation of the onset and minimum size of the calcium-mediated junction zone in alginate (2016)
Carbohydrate Polymers, 148, p. 52-60.
DOI: 10.1016/j.carbpol.2016.04.043

Qi, Sheng; Craig, Duncan.
Recent developments in micro- and nanofabrication techniques for the preparation of amorphous pharmaceutical dosage forms (2016)
Advanced Drug Delivery Reviews, 100, p. 67-84.
DOI: 10.1016/j.addr.2016.01.003

Yang, Xiao (Lead Author); Ding, Yanping; Ji, Tianjiao; Zhao, Xiao; Wang, Hai; Zhao, Xiaozheng; Zhao, Ruifang; Wei, Jingyan; Qi, Sheng; Nie, Guangjun.
Improvement of the in vitro safety profile and cytoprotective efficacy of amifostine against chemotherapy by PEGylation strategy (2016)
Biochemical Pharmacology, 108, p. 11-21.
DOI: 10.1016/j.bcp.2016.02.014

Ulaeto, David O.; Morris, Christopher J.; Fox, Marc A.; Gumbleton, Mark; Beck, Konrad.
Destabilization of α-helical structure in solution improves bactericidal activity of antimicrobial peptides: Opposing effects on bacterial and viral targets (2016)
Antimicrobial Agents and Chemotherapy, 60, 4, p. 1984-1991.
DOI: 10.1128/AAC.02146-15