introduction introduction

A study examining the most effective method to treat sub-acute hand oedema

Swelling after a hand injury or surgery is a normal part of the healing process. Prolonged swelling impacts on joint and soft tissue mobility and function appearance of the hand. These factors can delay a patient's recovery, return to work and daily activities, resulting in more frequent out-patient appointments. 

Assessment of swelling offers valuable information to the treating therapist about the effectiveness of interventions. Objective measures are particularly important in the current economic climate to ensure that interventions can be justified. Measures need not only to be reliable but also responsive to clinically important change over time.

The treatment of hand swelling is a constant challenge for therapists where the objective is to reduce the swelling quickly and effectively in order to focus therapy on more functionally related goals, such as return to work and usual activity. There is no consensus on what is the most effective method of treating hand swelling after trauma or surgery. With the introduction of novel therapeutic techniques and modalities to treat swelling there is a need to assess the efficacy of these when compared to standard treatment.

key research questions key research questions

This four year programme of research covers four interlinking projects, the aims of which are to:
  • review the quality and quantity of evidence on how hand swelling is measured and treated.
  • identify and describe current methods of measuring and treating hand swelling in the UK and develop consensus on best practice.
  • establish what is the best method of measuring hand swelling
  • establish the best way of treating hand swelling.

research design and outputs research design and outputs

To address these objectives, we have undertaken a number of different studies. Two systematic reviews have been completed which tell us which methods of assessing hand swelling have the best psychometric data, and which treatments have the best quality evidence. We have conducted a survey of clinical practice amongst UK based hand therapists and have compared the results of this with those of the systematic reviews. This highlighted that the assessments and treatments with the highest level of evidence are not those which are most commonly used in practice. A standardized treatment programme has been established following consensus development with experts in the field of hand therapy.

An observational study has identified which are the most responsive methods of assessing hand swelling. These include a clinician-derived assessment and a patient-rated outcome measure. These outcome measures will be used in a pilot randomized controlled trial comparing two commonly used treatments for hand swelling to establish if a newer method of reducing swelling shows potential when compared to standard treatment. Results of this may indicate that a definitive trial is required.

The results of these studies will inform clinical guidelines for how hand swelling should be assessed and treated in the future.


the research team the research team

Principal investigator: Leanne Miller NIHR/HEE Clinical Doctoral Research Fellow, MSc, BSc (Hons) Occupational Therapy, Accredited Hand Therapist.

Co-Investigators:  Professor Christina Jerosch-Herold and Professor Lee Shepstone  (UEA)

Patient and Public Involvement in Research: (PPIRes) Project Manager Jacqueline Romero and members of the patient advisory committee; Pauline Spedding, Chris Dell, Ann Dibben and Jon Craigie.

funding funding

Leanne Miller is funded by a NIHR/HEE Clinical Doctoral Research Fellowship.

Christina Jerosch-Herold is funded by an NIHR Senior Research Fellowship.

The content of this webpage presents independent research funded by the National Institute for Health Research (NIHR) and Health Education England. The views expressed are those of the authors and not necessarily those of the NHS, the NIHR or the Department of Health.