A rule-based, dose-finding design for use in stroke rehabilitation research: methodological development
Dose-optimisation studies as precursors to clinical trials are rare in stroke rehabilitation. Key Contact Prof Valerie Pomeroy
FAST INdICATE TRIAL: Clinical Efficacy of Functional Strength Training for upper limb motor recovery early after stoke: neural correlates and prognostic indicators
Weakness of the arm and hand after stroke affects peoples' everyday lives and their capacity for independent living. Some treatments may be beneficial but this largely depends on a patient's ability to participate actively in repetitive practice of everyday (functional) tasks. Patients with substantial weakness may not be able to do this.
FALLS: A falls prediction and prevention programme in older Adults with Rheumatoid Arthritis
Rheumatoid Arthritis (RA) is the most common form of Arthritis in the UK. The aim of this study is to obtain knowledge of the factors which make falls in older adults with RA more likely and to provide detailed guidance on falling prevention in patients with RA.
SWIFT Cast: Clinical efficacy of the Soft-Scotch Walking Initial FooT Cast (SWIFT Cast) on walking recovery early after stroke and the neural-biomechanical correlates of response
Weakness of the leg and foot is common after stroke. This affects peoples' everyday lives. For example, being unable to cross the road in the time allowed at most Pelican crossings.
SCIP-R: Supported Communication to Improve Participation in Rehabilitation of people with moderate-severe aphasia after stroke
About a third of people who have a stroke for the first time experience aphasia, a communication disorder affecting speaking, understanding, writing or reading. Aphasia is associated with longer stays in hospital and has severe consequences for all aspects of life. People with aphasia may not fully benefit from stroke rehabilitation for a number of reasons to do with their communication.
FeSTIvaLS: Feasibility of a randomized controlled trial of functional strength training for people between six months and five years after stroke
Every day we need to perform a wide range of movements, such as walking, lifting, pushing, pulling, bending and twisting. The purpose of Functional Strength Training (FST) is to work to improve strength in a way that the activities of daily living are easier to perform. This means practising tasks while gradually increasing the number of repetitions or making it harder bit by bit. FST is a progressive, resistive, low-intensity exercise.
RePed: Developing a clinical measure of lower limb motor impairment after stroke: Test-retest reliability and concurrent validity of upright pedalling
Objective and sensitive measurement of motor impairment after stroke in clinical settings is challenging. Clinical measures, e.g the Motricity Index (MI), do not provide i) biological insights into recovery or ii) information about movement performance during functional activities. Motion analysis systems are expensive and often inaccessible in clinical practice. This study is investigating test-retest reliability and concurrent validity of instrumented Upright Pedalling (UP) on an exercise bike as a potential objective sensitive clinical measure of motor impairment.