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Cells and Tissues

Abou-Elhamd A., Alrefaei A.F.*, Mok G.F.*, Garcia-Morales C., Abu-Elmagd M., Wheeler G.N. & Münsterberg A. (2015) Klhl31 attenuates beta-catenin dependent Wnt signaling and regulates embryo myogenesis. Dev. Biol., 402, pp. 61-71. *equal contribution

Abu-Elmagd M., Robson L., Sweetman D., Hadley J., Francis-West P. & Münsterberg A. (2010) Wnt/Lef1 signalling acts via Pitx2 to regulate somite myogenesis. Developmental Biology, 337, pp. 211-219.

Bass R., Werner F., Odintsova E., Sugiura T., Berditchevski F. & Ellis V. (2005) Regulation of urokinase receptor proteolytic function by the tetraspanin CD82. J. Biol. Chem., 280,  pp. 14811-14818.

Bass R. & Ellis V. (2009) Regulation of urokinase receptor function and pericellular proteolysis by the integrin alpha(5)beta(1). Thromb Haemost., 101, pp. 954-962.

Bass R., Wagstaff L., Ravenhill L. & Ellis V. (2009) Binding of extracellular maspin to beta1 integrins inhibits vascular smooth muscle cell migration. J Biol Chem., 284, pp. 27712-2720.

Bellett G., Carter J.M., Keynton J., Goldspink D., James C, Moss D.K. & Mogensen M.M. (2009) Microtubule plus-end and minus-end capture at adherens junctions is involved in the assembly of apico-basal arrays in polarised epithelial cells. Cell Motil. Cytoskel., 66, pp. 893-908.

Dawes L.J., Sleeman M.A., Anderson I.K., Reddan J.R. & Wormstone I.M. (2009) TGFβ/Smad4-dependent and independent regulation of human lens epithelial cells. Invest. Ophthalmol. Vis. Sci., 50, pp. 5318-5327.

Decock J., Hendrickx W., Thirkettle S., Gutiérrez-Fernández A., Robinson S.D. & Edwards D.R. (2015) Pleiotropic functions of the tumor- and metastasis-suppressing matrix metalloproteinase-8 in mammary cancer in MMTV-PyMT transgenic mice. Breast Cancer Res., 17:38.

Eldred J.A., Dawes L.J. & Wormstone I.M. (2011) The lens as a model for fibrotic disease. Phil. Trans. Roy. Soc. B, 366, pp. 1301-1319.

Ellison T.S., Atkinson S. J., Steri V., Kirkup B.M., Preedy M.E.J., Johnson R.T., Ruhrberg C., Edwards D.R., Schneider J.G., Weilbaecher K. & Robinson S.D. (2015) Suppression of β3-integrin in mice triggers a neuropilin-1-dependent change in focal adhesion remodelling that can be targeted to block pathological angiogenesis. Disease Models and Mechs., 8, pp. 1105-1119.

Goldspink D.A., Gadsby J.R., Bellett G., Keynton J., Tyrrell B.J., Lund E.K., Powell P.P., Thomas P. & Mogensen M.M. (2013) The microtubule end-binding protein EB2 is a central regulator of microtubule reorganisation in apico-basal epithelial differentiation. J. Cell Sci., 126, pp. 4000-4014.

Goljanek-Whysall K., Sweetman D., Abu-Elmagd M., Chapnik E., Dalmay T., Hornstein E. & Münsterberg A. (2011) MicroRNA regulation of Pax3 confers robustness to developmental timing of myogenesis. Proc. Natl. Acad. Sci. USA, 108, pp. 11936-11941.

Goljanek-Whysall K., Pais H., Rathjen T., Sweetman D., Dalmay T. & Münsterberg, A. (2012) Regulation of multiple target genes by miR-1/miR-206 is pivotal for C2C12 myogenesis. J. Cell Sci., 125, pp. 3590-3600.

Goljanek-Whysall K., Mok G.F., Fahad Alrefaei A., Kennerley N., Wheeler G.N. & Münsterberg A. (2014) myomiR-dependent switching of BAF60 variant incorporation into Brg1 chromatin remodeling complexes during embryo myogenesis. Development 141, pp. 3378-3387.

Hajihosseini M.K., Duarte R., Pegrum J., Donjacour A., Lana-Elola E., Rice D., Sharpe J. & Dickson C. (2008) Evidence that Fgf10 contributes to the skeletal and visceral defects of an Apert syndrom mouse model. Dev. Dynam., 238, pp. 376-385.

Hajihosseini M.K., De Langhe S.P., Lana-Elola E., Morrison H., Sparshott N., Kelly R., Sharpe J., Rice D. & Bellusci S. (2008) Localization and fate of Fgf10-expressing cells in the adult mouse brain implicate Fgf10 in control of neurogenesis. Mol. Cell. Neurosci., 37, pp. 857-868.

Kelwick R., Wagstaff L., Decock J., Roghi C., Cooley L.S., Robinson S.D., Arnold H., Gavrilović J.,  Jaworski D.M., Yamamoto K., Nagase H., Seubert B., Krüger A. & Edwards D.R. (2015) Metalloproteinase-dependent and –independent processes contribute to inhibition of breast cancer cell migration, angiogenesis and liver metastasis by ADAMTS-15. Int. J. Cancer 136, pp. E14-E26.

Kilpatrick L.M., Harris R.L., Owen K.A., Bass R., Ghorayeb C., Bar-Or A. & Ellis V. (2006) Initiation of plasminogen activation on the surface of monocytes expressing the type-II transmembrane serine protease matriptase. Blood, 108, pp. 2616-2623.

Mutungi G. (2008) The expression of NFATc1 in adult rat skeletal muscle fibres. Exp. Physiol., 93, pp. 399-406.

Ravenhill L., Wagstaff L., Edwards D.R., Ellis V. & Bass R. (2010) The G-helix of maspin mediates effects on cell migration and adhesion. J. Biol. Chem., 285, pp. 36285-36292.

Reynolds A., Parris A., Evans L., Lindqvist S., Sharp P., Lewis M., Tighe R. &  Williams M.R. (2007) Dynamic and differential regulation of NKCC1 by calcium and cAMP in the native human colonic epithelium. J. Physiol., 582, pp. 507-524.

Reynolds A., Wharton N., Parris A., Mitchell E., Sobolewski A., Kam C., Bigwood L., El Hadi A. Münsterberg A., Lewis, M., Speakman C., Stebbings W., Wharton R., Sargen K., Tighe R., Jamieson C., Hernon J., Kapur S., Oue N., Yasui W. & Williams M. (2014) Canonical Wnt signals combined with suppressed TGFbeta/BMP pathways promote renewal of the native human colonic epithelium. Gut 63, pp. 610-621.

Rhodes J.D.,  Russell S.L., Illingworth C.D., Duncan G. & Wormstone I.M. (2009) Regional differences in store-operated Ca2+ entry in the epithelium of the intact human lens.  Invest. Ophthalmol. Vis. Sci., 50, pp. 4330-4336.

Rodgers U.R., Kevorkian, L., Surridge A. K., Waters J.G., Swingler T.E., Culley K., Illman S., Lohi J., Parker A.E. & Clark I.M. (2009) Expression and function of matrix metalloproteinase (MMP)-28. Matrix Biol., 28, pp. 263-272.

Song J., McColl J., Camp E., Kennerley N., Mok G.F., McCormick D., Grocott T., Wheeler G.N. & Münsterberg A.E. (2014) Smad1 transcription factor integrates BMP2 and Wnt3a signals in migrating cardiac progenitor cells. Proc. Natl. Acad. Sci. U.S.A., 111, pp. 7337-7342.

Steri V., Ellison T. S., Gontarczyk A. M., Weilbaecher K., Schneider J. G., Edwards D., Fruttiger M., Hodivala-Dilke K. M. & Robinson S. D. (2014) Acute depletion of endothelial β3-integrin transiently inhibits tumor growth and angiogenesis in mice. Circulation Res., 114, pp. 79-91.

Surridge A. K., Rodgers U.R., Swingler T.E., Davidson R.K., Kevorkian, L., Norton R., Waters J.G., Goldring M.B., Parker A.E. & Clark I.M. (2009) Characterization and regulation of ADAMTS-16. Matrix Biol., 28, pp. 416-424.

Sweetman D., Smith T., Farrell E.R., Chantry A. & Münsterberg A. (2003) The conserved glutamine rich region of chick csal1 and csal3 mediates protein interactions with other spalt family members - implications for Townes-Brocks syndrome. J. Biol. Chem., 278, pp. 6560-6566.

Sweetman D., Goljanek K., Rathjen T., Oustanina S., Braun T., Dalmay T. & Münsterberg A. (2008) Specific requirements of MRFs for the expression of muscle specific microRNAs, miR-1, miR-206 and miR-133. Dev. Biol., 321, pp. 491-499.

Thomas P., Bagrij T., Campos-Toimil M. & Edwardson J.M. (2006) Mitochondria play a critical role in shaping the exocytotic response of rat pancreatic acinar cells. Cell Calcium, 39, pp. 57-63.

Tomlinson M.L., Rejzek M., Fidock M., Field R.A. & Wheeler G.N. (2009) Chemical genomics identifies compounds affecting Xenopus laevis pigment cell development. Molecular BioSystems, 5, pp. 376-384.

Tomlinson M.L., Guan P., Morris R.J., Fidock M., Rejzek M., Garcia-Morales C., Field R.A. & Wheeler G.N. (2009) A chemical genomic approach identifies matrix metalloptroteinases as playing an essential and specific role in Xenopus melanophore migration. Chemistry and Biology, 16, pp. 1-12.

Wormstone I.M., Wang L.X. & Liu C.S.C. (2009) Posterior capsule opacification. Exp. Eye Res., 88, pp. 257-269.

Yue Q.,Wagstaff L., Yang X., Weijer C. & Münsterberg A. ( 2008) Wnt3a mediated chemorepulsion controls movement patterns of cardiac progenitors and requires RhoA function. Development, 135, pp. 1029-1037.

Zhong J.L., Poghosyan Z., Pennington C.J., Scott X., Handsley M.M., Warn A., Gavrilovic J., Honert K., Kruger A., Span P.N., Sweep F.C.G.J. & Edwards D.R. (2008) Distinct functions of natural ADAM-15 cytoplasmic domain variants in human mammary carcinoma. Mol. Cancer Res., 6, pp. 383-394.

Organisms and Environment

Bretman A., Lawniczak M.K.N., Boone J.M. & Chapman T. (2009) A mating plug protein reduces early female remating in Drosophila melanogaster. J. Insect Physiology., 56, pp. 107-113.

Kearn, G.C. (2011). Monogeneans: the ultimate fish parasites. The Biologist, 58, pp. 28-32.

Kearn, G.C., Whittington, I.D. & Evans-Gowing, R. (2010). A new genus and new species of microbothriid monogenean (Platyhelminthes) with a functionally enigmatic reproductive system, parasitic on the skin and mouth lining of the largetooth sawfish, Pristis microdon, in Australia. Acta Parasitologica, 55, pp. 115-122.

Kearn G.C., Whittington I.D. & Thomas P. (2012) A new species of Asthenocotyle Robinson, 1961 (Monogenea: Microbothriidae), a skin parasite of the great lanternshark, Etmopterus princeps Collett from the Azores, with a redescription of A. kaikourensis Robinson, 1961 and observations on A. taranakiensis Beverley-Burton, Klassen & Lester, 1987. Syst. Parasitol., 83, pp. 145-158.

Whittington I.D. & Kearn G.C. (2011). A new species of Dermopristis (Monogenea: Microbothriidae), with observations on associations between the gut diverticula and reproductive system and on the presence of denticles in the nasal fossae of the host Glaucostegus typus (Bennett) (Elasmobranchii: Rhinobatidae). Systematic Parasitology, 80, pp. 41-51.

Molecular Microbiology

Barke J., Seipke R.F., Gruschow S., Heavens D., Drou N., Bibb M.J., Goss R.J.M., Yu D.W. and Hutchings M.I. (2010). A mixed community of actinomycetes produce multiple antibiotics for the fungus farming ant Acromyrmex octospinosus. BMC Biology 8, 109.

Dalton K.A., Thibessard A., Hunter J.I. & Kelemen G.H. (2007) A novel compartment, the 'subapical stem' of the aerial hyphae, is the location of a sigN-dependent, developmentally distinct transcription in Streptomyces coelicolor. Mol. Microbiol., 64, pp. 719-737.

Holmes N.A., Walshaw J., Leggett R.M., Thibessard A., Dalton K.A., Gillespie M.D., Hemmings A.M., Gust B. & Kelemen G.H. (2013) Coiled-coil protein Scy is a key component of a multiprotein assembly controlling polarized growth in Streptomyces. Proc. Natl. Acad. Sci. USA, 110, pp. E397-E406.

Ogunwobi O., Mutungi G. & Beales I.L.P. (2006) Leptin stimulates proliferation and inhibits apoptosis in Barrett's esophageal adenocarcinoma cells by cyclooxygenase-2-dependent, prostaglandin-E2-mediated transactivation of the epidermal growth factor receptor and c-Jun NH2-terminal kinase activation. Endocrinology, 147, pp. 4505-4516.

Redshaw N., Wheeler G., Hajihosseini M.K. & Dalmay T. (2009) microRNA-449 is a putative regulator of choroid plexus development and function. Brain Res., 1250, pp. 20-26.

Seipke R.F., Barke J., Brearley C., Hill, L., Yu D.W., Goss R.J.M. & Hutchings, M.I. (2011). A single Streptomyces mutualist makes multiple antifungals to support the fungus farming ant Acromyrmex octospinosus. PLoS ONE. 6:e22028.

Seipke R.F., Barke J., Ruiz-Gonzalez M.X., Orivel J., Yu D.W. & Hutchings M. I. (2011). Fungus-growing Allomerus ants are associated with antibiotic-producing actinobacteria. Antonie van Leeuwenhoek. DOI 10.1007/s10482-011-9621-y  

Thompson B.J., Widdick D.A., Hicks M.G., Chandra G., Sutcliffe I.C., Palmer T. & Hutchings M.I. (2010). Investigating lipoprotein biogenesis and function in the model Gram-positive bacterium Streptomyces coelicolor. Mol. Microbiol., 77, pp.943–957.

Tzanis A., Dalton K.A., Hesketh A., den Hengst C.D., Buttner M.J., Thibessard A. & Kelemen G.H. (2014) A sporulation-specific, sigF-dependent protein, SspA, affects septum positioning in Streptomyces coelicolor. Mol. Microbiol., 91, pp. 363-380.

Widdick D.A., Thompson B.J., Hicks M.G., Tschumi A., Chandra G., Sutcliffe I.C., Brulle J., Sander P., Palmer T. & Hutchings M.I. (2011) Dissecting the complete lipoprotein biogenesis pathway in Streptomyces scabies. Mol. Microbiol. 80, pp. 1395-1412.

Plant Sciences

Sweetman D., Johnson S., Caddick S.E.K., Hanke D.E. & Brearley C.A. (2006) Characterization of an Arabidopsis inositol 1,3,4,5,6-pentakisphosphate 2-kinase (Atlpk1). Biochem. J., 394, pp. 95-103.

Sweetman D., Stavridou I., Johnson S., Green P., Caddick S.E. & Brearley C.A. (2007) Arabidopsis thaliana inositol 1,3,4-trisphosphate 5/6-kinase 4 (AtITPK4) is an outlier to a family of ATP-grasp fold proteins from Arabidopsis. FEBS Lett., 581, pp. 4165-4171.

Zhang Y. & Turner J.G. (2008) Wound-induced endogenous jasmonates stunt plant growth by inhibiting mitosis. PLoS One, 3(11), e3699.


Ahire J.H., Chambrier I., Mueller A., Bao Y. & Chao Y. (2013) Synthesis of D-mannose-capped silicon nanoparticles and their interactions with MCF-7 human breast cancerous cells.  ACS Appl. Mater. Interfaces, 5, pp. 7384-7391.

Ahire J.H., Wang Q., Coxon P.R., Malhotra G., Brydson R., Chen R. & Chao Y. (2012) Highly luminescent and nontoxic amine-capped nanoparticles from porous silicon: synthesis and their use in biomedical imaging. ACS Appl. Mater. Interfaces, 4, pp. 3285–3292.

Ahire J.H., Behray M., Webster C.A., Wang Q., Sherwood V., Saengkrit N., Ruktanonchai U., Woramongkolchai N. & Chao, Y. (2015) Synthesis of carbohydrate-capped silicon nanoparticles and their reduced cytotoxicity, in vivo toxicity, and cellular uptake. Adv. Healthc. Mater., DOI: 10.1002/adhm.201500298.

Armbruester V., Sauter M., Roemer K., Best B., Hahn S., Nty A., Schmid A., Philipp S., Mueller A. & Mueller-Lantzsch N. (2004) Np9 protein of human endogenous retrovirus k interacts with ligand of numb protein x. J. Virol., 78, pp. 10310-10319.

Burguete M.I., Galindo F., Gavara R. Luis S.V., Moreno M., Thomas P. & Russell D.A. (2009) Singlet oxygen generation using a porous monolithic polymer supported photosensitizer: potential application to the photodynamic destruction of melanoma cells. Photochem. Photobiol. Sci., 8, pp. 37-44.

Butler C.E., de Carvalho T.M.U., Grisard E.C., Field R.A. & Tyler K.M. (2013) Trans-sialidase stimulates Eat Me response from epithelial cells. Traffic, 14, pp. 853-869.

Cottam E.M., Maier H.J., Manifava M., Vaux L.C., Schoenfelder P., Gerner W., Britton P., Ktistakis N.T. & Wileman T. (2011) Coronavirus nsp6 proteins generate autophagosomes from the endoplasmic reticulum via an omegasome intermediate. Autophagy, 7, pp. 1-13.

Cottam E.M., Whelband M.C. & Wileman T. (2014) Coronavirus nsp6 restricts autophagosome expansion. Autophagy, 10, pp. 1-16.

Galindo F., Kabir N., Gavrilovic J. & Russell D.A. (2008), Spectroscopic studies of 1,2-diaminoanthraquinone (DAQ) as a fluorescent probe for the imaging of nitric oxide in living cells. Photochem. Photobiol. Sci. 7, pp. 126-130.

Lalor R., Baillie-Johnson H., Redshaw C., Matthews S.E. & Mueller A. (2008) Cellular Uptake of a fluorescent calix[4]arene derivative. JACS (Communication), 130; 2892-2893.

Marín M.J., Thomas P., Fabregat V., Luis S.V., Russell D.A. & Galindo F. (2011) Fluorescence of 1,2-diaminoanthraquinone and its nitric oxide reaction product within macrophage cells. ChemBioChem, 12, pp. 2471-2477.

Marín M.J., Galindo F., Thomas P. & Russell D.A.(2012) Localized intracellular pH measurement using a ratiometric, photoinduced electron-transfer-based nanosensor. Angew. Chem. Int. Ed., 51, pp. 9657-9661.

Marín M.J., Galindo F., Thomas P., Wileman T. & Russell D.A. (2013) A photoinduced electron transfer based nanoprobe as a marker for acidic organelles in mammalian cells. Anal. Bioanal. Chem., 405, pp. 6197-6207.

Marsey L.L. & Winpenny J.P. (2009) Bestrophin expression and function in the human pancreatic duct cell line, CFPAC-1. J. Physiol., 587, pp. 2211-2224.

Obaid G., Chambrier I., Cook M. & Russell D.A. (2012) Targeting the oncofetal Thomsen-Friedenreich disaccharide using jacalin-PEG phthalocyanine gold nanoparticles for photodynamic cancer therapy. Angew. Chem. Int. Ed., 51, pp. 6158-6162.

Obaid G., Chambrier I., Cook M. & Russell D.A. (2015) Cancer targeting with biomolecules: a comparative study of photodynamic therapy efficacy using antibody or lectin conjugated phthalocyanine-PEG gold nanoparticles. Photochem. Photobiol. Sci., 14, pp. 737-747.

Osborne A.,Hopes, M., Wright P., Broadway D.C. & Sanderson, J. (2016) Human organotypic retinal cultures (HORCs) as a chronic experimental model for investigation of retinal ganglion cell degeneration. Exp. Eye Res., 143, pp. 28-38.

Roberts, R., Al-Jamal,  W., Whelband, M., Thomas, P., Jefferson, M., van den Bossche, J., Powell, P. P., Kostarelos, K. & Wileman, T. (2013) Autophagy provides a barrier against non-viral gene delivery. Autophagy, 9, pp. 667-682.

Saura V., Marín M.J., Burguete M.I., Russell D.A, Galindo F. & Luis S.V. (2015) Synthesis of new fluorescent bichromophoric compounds as ratiometric pH probes for intracellular measurements. Org. Biomol. Chem., 13, pp. 7736-7749.

Skoczek D.A., Walczysko P., Horn N., Parris A., Clare S., Williams M.R. & Sobolewski A. (2014) Luminal microbes promote monocyte-stem cell interactions across a healthy colonic epithelium. J. Immunol., 193, pp. 439-451.

Wadhavane P.D., Izquierdo M.Á., Lutters D., Burguete M.I., Marín M.J., Russell D.A., Galindo F. & Luis, S.V. (2014) Fluorescent macrocyclic probes with pendant functional groups as markers of acidic organelles within live cells. Org. Biomol. Chem., 12, pp. 823-831.

Wang Q., Bao Y., Zhang X., Coxon P.R., Jayasooriya U.A. & Chao Y. (2012) Uptake and toxicity studies of poly-acrylic acid functionalized silicon nanoparticles in cultured mammalian cells. Adv. Healthc. Mater., 1, pp. 189–198.

Wang Q., Bao Y., Ahire J.H. & Chao Y. (2012) Co-encapsulation of biodegradable nanoparticles with silicon quantum dots and quercetin for monitored delivery. Adv. Healthc. Mater., 2, pp. 459–466.



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