A selection of latest publications A selection of latest publications

The latest research publications and papers from within the school of Pharmacy.

Liso, M., De Santis, S., Scarano, A., Verna, G., Dicarlo, M., Galleggiante, V., Campiglia, P.,  Mastronardi, M., Lippolis, A., Vacca, M., Sobolewski, A., Serino, G., Butelli, E., De Angelis, M.,
Martin, C., Santino, A. & Chieppa, M.
A Bronze-Tomato Enriched Diet Affects the Intestinal Microbiome under Homeostatic and Inflammatory Conditions. (2018)
In: Nutrients. 10, 12, 1862
DOI: 10.3390/nu10121862

Carro, L.
Protein–protein interactions in bacteria: a promising and challenging avenue towards the discovery of new antibiotics. (2018)
In : Beilstein Journal of Organic Chemistry. 14, p. 2881-2896
DOI: 10.3762/bjoc

Katangwe, T., Bhattacharya, D. & Twigg, M. (2018)
A systematic review exploring characteristics of lifestyle modification interventions in newly diagnosed type 2 diabetes for delivery in community pharmacy.
(Accepted/In press) In : International Journal of Pharmacy Practice

Redox Modulation at Work: Natural Phytoprotective Polysulfanes From Alliums Based on Redox-Active Sulfur. (2018)
Anwar, A., Gould, E., Tinson, R., Iqbal, J. & Hamilton, C.
In : Current Pharmacology Reports. 4, 5, p. 397–407
DOI: 10.1007/s40495-018-0153-2

Nartowski, K., Malhotra, D., Hawarden, L., Fabian, L. & Khimyak, Y.
Nanocrystallization of Rare Tolbutamide Form V in Mesoporous MCM-41 Silica. (2018)
In : Molecular Pharmaceutics.
DOI: 10.1021/acs.molpharmaceut.8b00575

Kay, K. L., Hamilton, C. J. & Le Brun, N. E.
Mass spectrometric studies of Cu(I)-binding to the Nterminal domains of B. subtilis CopA and influence of bacillithiol. (2018)
In : Journal of Inorganic Biochemistry. 190, p. 24-30
DOI: 10.1016/j.jinorgbio.2018.10.004

Easthall, C., Taylor, N. & Bhattacharya, D.
Barriers to medication adherence in patients prescribed medicines for the prevention of cardiovascular disease: a conceptual framework. (2018)
In : International Journal of Pharmacy Practice.
DOI: 10.1111/ijpp.12491

Alhijjaj, M., Belton, P., Fabian, L., Wellner, N., Reading, M. & Qi, S.
A novel thermal imaging method for rapid screening of drug-polymer miscibility for solid dispersion based formulation development. (2018)
In : Molecular Pharmaceutics.
DOI: 10.1021/acs.molpharmaceut.8b00798

Abdelhamid, M. A. S., Gates, A. J. & Waller, Z. A. E.
Destabilization of i-Motif DNA at Neutral pH by GQuadruplex Ligands. (2018)
DOI: 10.1021/acs.biochem.8b00968

Wright, D., Scott, S., Buck, J. & Bhattacharya, D.
Roles of nurses in supporting proactive deprescribing. (2018)
(Accepted/In press) In: Nursing Standard.

R., Rejzek, M., Wegmann, U., Le Gall, G., Kavanaugh, D. W., Colquhoun, I., Frese, S., MacKenzie, D. A., Walter, J., Angulo, J., Field, R. & Juge, N.
Serine-Rich Repeat Protein adhesins from Lactobacillus reuteri display strain specific glycosylation profiles Latousakis, D., Nepravishta.(2018)
(Accepted/In press) In : Glycobiology.
DOI: 10.1093/glycob/cwy100

Brown, T. J., Twigg, M., Taylor, N., Easthall, C., Hartt, J., Budd, T., Li, Z., Dima, A. & Bhattacharya, D.
Final Report for the IMAB-Q study: Validation and Feasibility Testing of a Novel Questionnaire to Identify Barriers to Medication Adherence. (2018)
Pharmacy Research UK.

Scott, S., Clark, A., May, H.& Bhattacharya, D.
Validation and Feasibility of the Medication Acceptability Questionnaire to Investigate Tablet and Liquid Alendronic Acid with Older Hospital Patients. (2018)
Pharmacy. 6, 11 p., 84
DOI: 10.3390/pharmacy6030084.

Craske, M., Wright, D., Blacklock, J., Matthews, H., Dean, T., Farrow, T., Daly, C. & Duell, P.
Testing annual asthma reviews for those who fail to attend: proof-of-concept study. (2018)
The Pharmaceutical Journal. 8, 10, p. 243-249 7 p.

Calabrese, V., da Silva, M. A., Schmitt, J., Muñoz- Garcia, J. C., Gabrielli, V., Scott, J. L., Angulo, J., Khimyak, Y. Z. & Edler, K. J.
Surfactant controlled zwitterionic cellulose nanofibril dispersions. (2018)
Soft Matter.
DOI: 10.1039/C8SM00752G

Abdelhamid, M. A. S., Fábián, L., MacDonald, C. J., Cheesman, M. R., Gates, A. J. & Waller, Z. A. E.
Redox-dependent control of i-Motif DNA structure using copper cations. (2018)
Nucleic Acids Research.
DOI: 10.1093/nar/gky390

Nasereddin, J. M., Wellner, N., Alhijjaj, M., Belton, P., Qi, S.
Development of a Simple Mechanical Screening Method for Predicting the Feedability of a Pharmaceutical FDM 3D Printing Filament. (2018)
Pharmaceutical Research 35 (8) article no. 151
DOI: 10.1007/s11095-018-2432-3

Twigg M, Wright D, Barton G, Kirkdale CL, Thornley T.
The pharmacy care plan service: Service evaluation and estimate of cost-effectiveness. (2018)
Research in Social & Administrative Pharmacy. PII: S1551-7411(17)30838-0 
DOI: 10.1016/j.sapharm.2018.03.062

Abdelhamid, MAS, Fábián, L, MacDonald, CJ, Cheesman, MR, Gates, Zoë AE Waller.
Redox-dependent control of i-Motif DNA structure using copper cations. (2018)
Nucleic Acids Research, gky390,
DOI: 10.1093/nar/gky390

Marín-Barba M, Gavilán H, Gutiérrez L, Lozano-Velasco E, Rodríguez-Ramiro I, Wheeler GN, Morris CJ, Morales MP, Ruiz A.
Unravelling the mechanisms that determine the uptake and metabolism of magnetic single and multicore nanoparticles in a Xenopus laevis model (2018).
Nanoscale. Jan 3;10(2):690-704.
DOI: 10.1039/C7NR06020C.

Al-Jabr H, Twigg MJ, Scott S, Desborough JA.
Patient feedback questionnaires to enhance consultation skills of healthcare professionals:  A systematic review. (2018)
Patient Educ Couns.
DOI: 10.1016/j.pec.2018.03.016

Tipduangta P, Takieddin K, Fábián L, Belton P, Qi S
Towards controlling the crystallisation behaviour of fenofibrate melt: triggers of crystallisation and polymorphic transformation. (2018)
RSC Adv., 8, 13513-13525
DOI: 10.1039/C8RA01182F

Matthews, SE, S Cecioni, S, O'Brien, J E, MacDonald, C J, Hughes, D L, Jones, G A, Ashworth, S H, Vidal, S
Fixing the Conformation of Calix[4]arenes: When Are Three Carbons Not Enough? (2018)
Chem. Eur. J, 24, 17, 4436-4444
DOI: 10.1002/chem.201705955

Mills SC, Howell L, Beekman A, Stokes L, Mueller A.
Rac1 plays a role in CXCL12 but not CCL3-induced chemotaxis and Rac1 GEF inhibitor NSC23766 has off target effects on CXCR4. (2018)
Cell Signal. Jan;42:88-96.
DOI: 10.1016/j.cellsig.2017.10.006. Epub 2017 Oct 16.

Hung MY, Wright D, Needle R.
Identification of the benefits, enablers and barriers to integrating junior pharmacists into the ward team within one UK-based hospital. (2017)
Integrated Pharmacy Research and Practice; 6:181-90

Boughen M, Sutton J, Fenn T, Wright D.*
Defining the role of the pharmacy technician and identifying their future role in medicines optimisation. (2017)
Pharmacy. Jul 15;5(3). pii: E40.
DOI: 10.3390/pharmacy5030040.

Millar AN, Daffu-O'Reilly A, Hughes CM, Alldred DP, Barton G, Bond CM, Desborough JA, Myint PK, Holland R, Poland FM, Wright D; CHIPPS Team, University of East Anglia
Development of a core outcome set for effectiveness trials aimed at optimising prescribing in older adults in care homes. (2017)
Trials. Apr 12;18(1):175.
DOI: 10.1186/s13063-017-1915-6.

Wright D, Begent D, Crawford H, Foundling Miah M, Griffith R, Merriman H.
Medication management of adults with swallowing difficulties.
Guidelines November 2017; Medendium Group Publishing Ltd.

Minshan Guo, Ke Wang, Ning Qiao, László Fábián, Ghazala Sadiq⊥, and Mingzhong Li
Insight into Flufenamic Acid Cocrystal Dissolution in the Presence of a Polymer in Solution: from Single Crystal to Powder Dissolution. (2017)
Mol. Pharmaceutics, 2017, 14 (12), pp 4583–4596
DOI: 10.1021/acs.molpharmaceut.7b00712

Marín-Menéndez, Alejandro; Montis, Costanza; Díaz-Calvo, Teresa; Carta, Davide; Hatzixanthis, Kostas; Morris, Christopher J; McArthur,Michael; Berti, Debora.
Antimicrobial Nanoplexes meet Model Bacterial Membranes: the key role of Cardiolipin. (2017).
Scientific Reports 7, Article number: 41242

Cadman, Brit; Wright, David; Bale, Amanda; Barton, Garry; Desborough, James; Hammad, Eman A; Holland, Richard; Howe, Helen; Nunney, Ian; Irvine, Lisa.
Pharmacist provided medicines reconciliation within 24 hours of admission and on discharge: a randomised controlled pilot study. (2017)
BMJ Open, 7:e013647
DOI: 10.1136/bmjopen-2016-013647

Morris CJ, Aljayyoussi G, Mansour O, Griffiths P, Gumbleton M.
Endocytic Uptake, Transport and Macromolecular Interactions of Anionic PAMAM Dendrimers within Lung Tissue (2017).
Pharm Res. Dec;34(12):2517-2531.
DOI: 10.1007/s11095-017-2190-7

Cationic liposomal vectors incorporating a bolaamphiphile for oligonucleotide antimicrobials (2017).
Mamusa M, Sitia L, Barbero F, Ruyra A, Calvo TD, Montis C, Gonzalez-Paredes A, Wheeler GN, Morris CJ, McArthur M, Berti D.
Biochim Biophys Acta. Oct;1859(10):1767-1777.
DOI: 10.1016/j.bbamem.2017.06.006.

Twigg MJ, Wright D, Kirkdale CL, Desborough JA, Thornley T.
The UK Pharmacy Care Plan service: Description, recruitment and initial views on a new community pharmacy intervention. (2017)
PLoS ONE 12(4): e0174500.
DOI: 10.1371/journal.pone.0174500

Alhijjaj M, Belton P, Qi S.
An investigation into the use of polymer blends to improve the printability of and regulate drug release from pharmaceutical solid dispersions prepared via fused deposition modeling (FDM) 3D printing. (2016)
Eur. J. Pharm & Biopharm., 108, pp 111–125,
DOI: 10.1016/j.ejpb.2016.08.016