Seminars
Shrinking bias to benefit estimation and inference in statistical models
Location : New venue - School meeting room (S2.29) Date : 25 Jan 2013 (13:00-14:00) Speaker : Dr. Ioannis Kosmidis Organiser : Dr. Katharina Huber Institution : Dept. of Statistical Science, University College London Abstract In this talk recent work on a unified computational and conceptual framework for reducing the bias in the estimation of statistical models is presented from a practitioners point of view. The talk will discuss several...
Making use of external information on heterogeneity and biases in meta-analysis
Location : SCI 0.67 Date : 30th Jan 2013 (12:00-13:00) Speaker : Dr Rebecca Turner Organiser : Prof. Elena Kulinskaya Institution :Cambridge MRC Biostatistics Unit Abstract Many meta-analyses contain only a small number of studies, making it difficult to estimate the extent of between-study heterogeneity. An additional problem is that the original studies are often affected by varying amounts of internal bias caused by methodological flaws. Standard...
Extreme reviewing: Use of text-mining to reduce impractical screening workload in extremely large reviews
Location : D'Arcy Thompson Room Date : 27 Feb 2013 (12:00-13:00) Research Group : East Anglian Research Synthesis Speaker : Dr. Ian Shemilt Organiser : Prof. Elena Kulinskaya Institution : Behaviour and Health Research Unit, Institute of Public Health, University of Cambridge Background : In scoping reviews of broad evidence bases, boundaries of relevant evidence may initially be fuzzy, with a refined conceptual understanding of...
Evolutionary Neural Networks
Location : D'Arcy Thompson Room (School of Computing Sciences, UEA) Date : 1st March 2013 (13:00-14:00) Speaker : Assoc Prof Grant Braught Institution : Department of Mathematics & Computer Science, Dickinson College, USA Artificial neural networks and evolutionary algorithms are computational abstractions inspired by nervous systems and natural selection. When combined, evolutionary algorithms can be used to find and optimize neural networks for...
Computational Topology in Graphics and Visualization
Location : D'Arcy Thompson Room (School of Computing Sciences, UEA) Date : 22nd March 2013 (13:00-14:00) Speaker : Dr Hamish Carr I nstitution : School of Computing, University of Leeds In the last decade and a half, topological structures such as the Contour Tree, the Reeb Graph and the Morse- Smale Complex have increasingly been relied on in computer graphics and scientific visualization. This talk will give an overview of this area of...
Crowdsourcing the German outbreak E.coli, 2011 and beyond
Location : D'Arcy Thompson Room (School of Computing Sciences, UEA) Research Group : Computational Biology Date : 18 Jan 2013 (14:00-15:00) Speaker : Dr Lisa Crossman, The Genome Analysis Center Abstract : A serious foodbourne outbreak hit Germany in May 2011. The source of the outbreak was not immediately traceable. Falling costs and rising speed of next generation sequencing allowed a real time investigation into the DNA sequence of the causal...
Reviewing for the Cochrane Collaboration
Location : D'Arcy Thompson Room Date : 19 Dec 2012 (12:00-13:00) Research Group : East Anglian Research Synthesis Speaker : Dr. Katherine Deane (NSC) Organiser : Prof. Elena Kulinskaya Institution : School of Nursing Sciences, UEA Reviewing for the Cochrane Collaboration Writing reviews for the Cochrane Collaboration is challenging but rewarding - and this seminar aims to give you a few tips on how to make a success of it: What sorts of reviews do Cochrane want? ...
Building mineable disease pathways from routinely collected hospital data - CANCELLED
Location : D'Arcy Thompson Room, School of Computing Sciences, UEA Date : 19 Dec 2012 (13:00-14:00) Research Group : Machine Learning and Statistics Speaker : Dr. Beatriz De La Iglesia Organiser : Prof. Elena Kulinskaya Institution : School of Computing Sciences, UEA Abstract Routinely collected data in hospitals is typically heterogeneous and scattered across multiple information systems (HIS). We introduce a framework for the construction of authoritative patient...
What colours do the colour blind people really see?
Location : D'Arcy Thompson Room, School of Computing Sciences Date : 7 Dec 2012 (13:00-14:00) Research Group : CMP Seminar Speaker : Prof Alexander Logvinenko Organiser : Dr. Katharina Huber Institution : School of Health and Life Sciences, Glasgow Caledonian University Abstract Most individuals are equipped with photoreceptors of three types (cones) with the peak sensitivity in the short (S), middle (M), and long (L) wavelength regions of the visible spectrum. They...
Research synthesis methods: applications and challenges
Location : EDU 0.112 Date : 28 Nov 2012 (12:00-13:00) Research Group : East Anglian Research Synthesis Speaker : Professor Fujian Song (NMS) Organiser : Dr. Katharina Huber Institution : Norwich Medical School, UEA Research synthesis methods: applications and challenges (PDF, 203Kb)
Parameterized algorithms for geometric problems
Location : D'Arcy Thompson Room, School of Computing Sciences Date : 23 Nov 2012 (13:00-14:00) Research Group : CMP Seminar Speaker : Prof Andreas Spillner Organiser : Dr. Katharina Huber Institution : Department of Mathematics and Computer Science, University of Greifswald, Germany Parameterized algorithms have been shown to be a powerful tool for computing exact solutions for instances of NP-hard problems that arise in applications ranging from computational biology to...
The Art of Decision Making in Software Engineering
Location : D'Arcy Thompson Room, School of Computing Sciences, UEA Date : 12.30-13:30 14 Nov 2012 Research Group : Machine Learning and Statistics Speaker : Dr. Joost Noppen Organiser : Prof. Elena Kulinskaya Institution : School of Computing Sciences, UEA Abstract The development of software systems, as any other complex development process, is driven by decisions on all kinds of subjects, ranging from deciding how to interpret requirements and the budget that is...
If nothing happens, is everything alright?
Location : D'Arcy Thompson Room Date : 31 Oct 2012 (12:00-13:00) Research Group : East Anglian Research Synthesis Speaker : Dr. Yoon Loke (NMS) Organiser : Prof. Elena Kulinskaya Institution : Norwich Medical School, UEA While systematic reviews and meta-analyses are top of the evidence hierarchy, most of the work has concentrated on evaluation of treatment benefit, rather than adverse effects or harm. There are unique methodological challenges stemming from the diversity...
Modelling the effect of copper availability on bacterial denitrification
Location : D'Arcy Thompson Room, School of Computing Sciences, UEA Date : 14:00-15:00 26 Oct 2012 Research Group : Computational Biology Speaker : Dr. Hugh Woolfenden Organiser : Dr. Katharina Huber Institution : School of Computing Sciences, UEA Abstract When bacteria such as Paracoccus denitrificans respire anaerobically they convert nitrate (NO3-) to dinitrogen (N2) gas via a pathway which includes the potent greenhouse gas, nitrousoxide (N2O). The copper...
Extreme reviewing: Use of text-mining to reduce impractical screening workload in extremely large reviews
Location : D'Arcy Thompson Room Date : 27 Feb 2013 (12:00-13:00) Research Group : East Anglian Research Synthesis Speaker : Dr. Ian Shemilt Organiser : Prof. Elena Kulinskaya Institution : Behaviour and Health Research Unit, Institute of Public Health, University of Cambridge Background : In scoping reviews of broad evidence bases, boundaries of relevant evidence may initially be fuzzy, with a refined conceptual understanding of...
The Origami of Breakage-Fusion-Bridge cycles
Location: D'Arcy Thompson Room, School of Computing Sciences, UEA Date: 14:00-15:00 12 Oct 2012 Speaker: Dr. Chris D Greenman Organiser: Dr. Katharina Huber Institution: Synergy Lecturer, School of Computing Sciences, UEA; The Genome Analysis Centre, NRP Paper folding sequences are a binary representation of the troughs and valleys that arise when a folded piece of paper is unravelled, and their generation can be modelled as an automaton process. The breakage...
Making use of external information on heterogeneity and biases in meta-analysis
Location : SCI 0.67 Date : 30th Jan 2013 (12:00-13:00) Speaker : Dr Rebecca Turner Organiser : Prof. Elena Kulinskaya Institution :Cambridge MRC Biostatistics Unit Abstract Many meta-analyses contain only a small number of studies, making it difficult to estimate the extent of between-study heterogeneity. An additional problem is that the original studies are often affected by varying amounts of internal bias caused by methodological flaws. Standard...
Shrinking bias to benefit estimation and inference in statistical models
Location : New venue - School meeting room (S2.29) Date : 25 Jan 2013 (13:00-14:00) Speaker : Dr. Ioannis Kosmidis Organiser : Dr. Katharina Huber Institution : Dept. of Statistical Science, University College London Abstract In this talk recent work on a unified computational and conceptual framework for reducing the bias in the estimation of statistical models is presented from a practitioners point of view. The talk will discuss several...
Making use of external information on heterogeneity and biases in meta-analysis
Location : SCI 0.67 Date : 30th Jan 2013 (12:00-13:00) Speaker : Dr Rebecca Turner Organiser : Prof. Elena Kulinskaya Institution :Cambridge MRC Biostatistics Unit Abstract Many meta-analyses contain only a small number of studies, making it difficult to estimate the extent of between-study heterogeneity. An additional problem is that the original studies are often affected by varying amounts of internal bias caused by methodological flaws. Standard...
Crowdsourcing the German outbreak E.coli, 2011 and beyond
Location : D'Arcy Thompson Room (School of Computing Sciences, UEA) Research Group : Computational Biology Date : 18 Jan 2013 (14:00-15:00) Speaker : Dr Lisa Crossman, The Genome Analysis Center Abstract : A serious foodbourne outbreak hit Germany in May 2011. The source of the outbreak was not immediately traceable. Falling costs and rising speed of next generation sequencing allowed a real time investigation into the DNA sequence of the causal...