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News
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ARRISA-UK Study Update - May 2022 - Research nearing completion
The study has randomised all of the needed GP Practices; and no longer needs to recruit more practices.
The ARRISA observation period for all practices has ended, but this isn’t the end of the study! We had a lot of data to collect. Here’s a brief summary of what’s been happening for ARRISA over the last few months…
NHS Digital have granted permission to access secondary care data in England and link the two datasets – a huge milestone for the study.
Our funder (NIHR) has funded an extension to cover the costs and time to link primary and secondary care data, with a new study end date of 31/10/2022.
As COVID lockdown eased, our focus once again returned to completing the study as quickly as possible. Our sponsor and CRN agreed that we should be able to proceed as no patient facing work was required. We needed to contact practices to agree an updated data processing agreement and last steps.
We want to give a big thank you! 244 GP practices, over 90% of those participating, have completed primary care data extraction with our partners OPC; The secondary care data requests to NHS Digital in England, PHS in Scotland and NWIS in Wales are also proceeding.
We have begun work on the data analysis required for the analysis of the study and will disseminate that as soon as possible, likely in Early 2023.
Publish Date
18/05/22
Practice Randomisation Closed
As of 30/4/2108 GP practice randomisation is now closed. Because of the practices in the pipeline, having completed almost all of the tasks for randomisation at the point of closing down the randomisation process, and also concerns to address a small number of practices withdrawing from the intervention, in discussion with the trial Data Monitoring Committee (DMC), in total 275 practices were randomised. 139 are in the Intervention arm while 136 are in the control arm.
Work in now ongoing to complete the implementation at these practices.
It should be noted that recruitment of study participants will continue insofar as further GP practice staff may participate in the training and in completion of study data collection tools. Also participants in the interviews and focus groups will continue for the following year.
By Stanley Musgrave
Publish Date
01/05/18
Recruitment update
Thanks to all the hard work from practices and UKCRN, we have randomised a total of 241 practices so far, and are now moving into the final stages of recruitment. We’re still looking to boost ours numbers in Scotland, so if you know of any Scottish practices (particularly those using Vision) who might be interested please ask them to contact the study team.
By Stanley Musgrave
Publish Date
02/03/18
Confirmation that ARRISA is still recruiting
We have heard from sources in 2 different regions of the country that they have heard that the ARRISA study has filled its recruitment target. This is not at all true, but it is an interpretation that can arise from an incomplete look at our data from the UKCRN ODP platform. The problem is that our “Target” is expressed in GP Practices and it is 262 practices, while at the same time the recruitment achievement -accruals- is now ~450 (and thus appears to be 171% of target). However the 450 accruals are participants – people - GP surgery staff, and there are 3 or more per practice. A classic apples and oranges comparison.
The information that explains this situation; that our target is expressed in "GP Practices" and that the number of our our accruals -expressed in "persons/participants" - and thus will be much larger, is in the separate field: "Description of Sample Size". The ARRISA-UK study design is different from most studies and measuring study progress by a simple division of "Participants recruited to-date" by "Study Level Targets", which works appropriately for other studies, is completely misleading for ARRISA. It results in an apparently vast overestimate of our recruitment. And unfortunately there is no place readily visible in the UKCRN CPMS site where this can be made clear.
At our current 143 randomised practices we are at about 55% of our target of practices - doing well, but needing to recruit many more.
So. We just want to say: Pay no attention to anyone who tells you that ARRISA-UK has already recruited to and beyond its target. (Or even, though only if you want to, please correct them.)
By Stanley Musgrave
Publish Date
05/09/17
Practice Recruitment continues
The study has now randomised 143 practices.
-We anticipate that we will continue to recruit and randomise practice into the study until early 2018.
By Stanley Musgrave
Publish Date
31/08/17
Practice Recruitment over halfway complete!
The ARRISA-UK Trial has recruited over half of the target of 262 practices for the study. The magic halfway point of 131 was passed today.
By Stanley Musgrave
Publish Date
03/08/17
Webinars Started
The first Webinar for intervention practices has been successfully held by Dr Mike Noble of the Acle Medical Practice via the Cisco Webex platform. It is an opportunity for intervention practices to have a chance to review and discuss the training, asking any questions about the intervention at their practice.
By Stanley Musgrave
Publish Date
27/04/17
ARRISA Online Training Starts
The first intervention practices in ARRISA have been given their links to the online training website.
By Stanley Musgrave
Publish Date
07/04/17
The ARRISA-UK study has begun randomisation of GP practices.
Practice randomisation has begun in the ARRISA-UK study among the practices which had previously expressed an interest in the study, completed the GP Survey have recently done the searches to identify patients with increased at risk for severe asthma events. This has started in the Norfolk area and the study will roll out from there. In addition several other practices are in the final stages of setup.
There have been a further 65+ practices which have expressed interest and are at various stages of doing the initial practice survey, contractual signup with UEA, and initial patient searches to identify at risk patients. These are in locations around Kent & Medway, Wessex, and the North Thames region of London. Further invitations to participate in the study have been and are being sent to practices in the Eastern Region. Work to expand the study to other regions is underway, including Scotland, Wales, South West Peninsula, Greater Manchester, East Midlands and the North East.
By Stanley Musgrave
Publish Date
16/06/16
Practice recruitment has resumed. We will be in touch with interested practices as soon as possible.
Practice recruitment has resumed. We will be in touch with interested practices as soon as possible.
By Lee Kitchman
Publish Date
30/05/16