multidisciplinary dementia research multidisciplinary dementia research

The demenTia Research And Care Clinic (TRACC) aims to become a centre of excellence in the field of dementia research. An expert multidisciplinary team, working in close contact with local NHS staff, will follow participants longitudinally from diagnosis (or even pre-diagnosis). This transdiagnostic study involves multiple neurodegenerative conditions, such as Alzheimer’s disease and frontotemporal dementia, which have varying structural changes in the brain but overlapping cognitive and behavioural changes. A comprehensive assessment package, including neuropsychological measures, biological samples, and brain imaging, will generate data to inform key research questions. The newly gained knowledge from this study will lead to improved diagnostic accuracy, even in the early stages, which will increase the efficacy of new disease modifying therapies.

key research aims key research aims

1. To longitudinally track disease progression in patient participants across various neurodegenerative conditions and measure cognitive, functional, and behavioural changes.

2. To track carers’ coping and wellbeing directly related to their role as a carer, and the relationship between these factors and changes in the participant.

3. To understand how alterations in brain structure and function, as well as blood, genetic, and nutritional biomarkers, relate to cognitive and behavioural changes.

4. To develop novel assessment tools, to improve differentiation between neurodegenerative diagnoses, and measurement of disease progression.

5. To improve measures of carer experience, which will inform novel carer interventions that support both patients and their carers.

research design research design

Participants will first have a home screening visit, where a member of the research team will conduct a dementia screening assessment. Participants may then be invited to a TRACC appointment, at our research clinic based at Hammerton Court, Norfolk and Suffolk Foundation Trust (NSFT). This TRACC visit may involve a combination of neuropsychological testing, clinical interviews, blood, stool, urine samples, and neuroimaging. Families may then be invited to return to the TRACC clinic on a yearly basis, where the same combination of assessments will be administered.

the research team the research team

Chief Investigator: Professor Michael Hornberger (UEA)

UEA
Professor Eneida Mioshi
Dr Stephen Jeffs
Emma Flanagan

Norfolk and Suffolk Foundation Trust (NSFT)

Dr Suvarna Wagle
Dr Bonnie Teague
Caroline Sheldon
Claire Rischmiller
Zoe Inman
Michelle Hagon-Powley
Louise McCarthy

Norfolk and Norwich University Hospital (NNUH)

Dr Ian Coyle-Gilchrist

Contact us Contact us

For further information about the TRACC study, please contact us via email, phone, or post:

TRACC.study@uea.ac.uk

01603 591623

The TRACC Team
Norwich Medical School
Floor 2, Bob Champion Research and Education Building
James Watson Road
University of East Anglia
Norwich Research Park
Norwich
NR4 7UQ