The Mass Spectrometry Platform houses a number of MS instruments offering analysis of a range of different samples.

Triple Quadrupole Inductively Coupled Plasma Mass Spectrometry ICP-MS-QQQ

A Thermo Icap-TQ uses ICP-MS technique, the most powerful technique for the analysis and quantification of trace elements in both solid and liquid samples. Its applications range from analysis of environmental and geological samples, to clinical research, material sciences and the semiconductor industry.

Matrix-Assisted Laser Desorption/Ionization-Time Of Flight Mass Spectrometry (MALDI-TOF MS)

The Shimadzu AXIMA Performance MALDI TOF/TOF is a highly flexible research grade mass spectrometer capable of analysing molecules from 1 – 500 kDa, and utilising linear, reflectron and MS/MS modes. It has various research applications and is often used for the analysis of biomolecules such as proteins and DNA and large organic molecules such as polymers.

High Resolution Liquid Chromatography Mass Spectrometry (LC-TOF)

A Waters SYNAPT XS with ACQUITY H-Class PLUS UPLC allows accurate mass analysis of molecules ranging from 20 to 32,000 m/z. Mass accuracy is ordinarily better than 2ppm. Ion Mobility Separation allows the resolution of ions of the same mass. Extras including nano spray source, ETD detector and an optional GC front end make this an extremely versatile research tool with a multitude of applications.

Gas Chromatography Mass Spectrometry (GC-MS)

In addition to the GC front end on the Waters LCMS we have a Perkin Elmer Clarus 500 GC-MS uses GC-MS technique.

GC–MS is a hyphenated technique developed from the coupling of GC and MS. Mass spectra acquired by this hyphenated technique offer more structure-related information based on the interpretation of fragmentations of the ions. The fragment ions with different relative abundances can be compared with the library spectra. The technique has many biological and chemical applications.

 

All enquiries are welcome and should initially be addressed to Dr Philip Wilson, Instrument Platform Manager: P.Wilson1@uea.ac.uk 01603 591860

Academic Lead: Prof Nick Le Brun

Support Lead: Graham Chilvers