Norwich Clinical Trials Unit

We currently have over 30 trials in set up, recruitment or follow up phases. Our trials include national multicentre studies and complex single centre trials with grant funding from a wide variety of NIHR, Research Council and charitable funding streams. In total, these cover 400 sites and include 28,000 patients.

We are investigating interventions including Drugs, screening, rehabilitation, lifestyle modifications and health service delivery.

Trials currently in set-up and recruitment include:

The impact of acute systemic inflammation upon cerebrospinal fluid and blood biomarkers of brain inflammation and injury in dementia: a study in acute hip fracture and memory clinic patients

Chief Investigator: Prof Chris Fox, University of East Anglia

A multi-centre cluster randomised controlled trial to evaluate the Guide to Action Care Home (GtACH) fall prevention programme in old age UK care homes

Chief Investigator: Prof Pip Logan, University of Nottingham

Development, evaluation and implementation of molecular diagnostics for hospital-acquired and ventilator-associated pneumonia in diverse UK hospital settings

Chief Investigators: Dr Vanya Gant, University College London and Prof David Livermore, University of East Anglia

Cognitive Behavioural Therapy for the treatment of post-traumatic stress disorder (PTSD) in youth exposed to multiple traumatic stressors: a phase II randomised controlled trial.

Chief Investigator: Dr Richard Meiser-Stedman, University of East Anglia

Study of Mirtazapine or carBamazepine for Agitation in Dementia

Chief Investigator: Prof Sube Banerjee, Brighton and Sussex Medical School

The Care Homes Independent Prescriber Pharmacist Study

Chief Investigator: Prof David Wright, University of East Anglia
 

At-Risk Registers Integrated into primary care to Stop Asthma crises in the UK (ARRISA-UK): A pragmatic cluster randomised trial with nested economic and process evaluations examining the effects of integrating at-risk asthma registers into primary care with internet-based training and support

Chief Investigator: Prof Andrew Wilson, University of East Anglia

Management of dementia and hip fracture: qualitative and quantitative evaluation

Chief Investigator: Prof Chris Fox, University of East Anglia