All Publications

Abdul-Aziz, A. M., Shafat, M. S., Sun, Y., Marlein, C. R., Piddock, R. E., Robinson, S. D., Edwards, D. R., Zhou, Z., Collins, A., Bowles, K. M., Rushworth, S. A.

(2018)

HIF1α drives chemokine factor pro-tumoral signaling pathways in acute myeloid leukemia,

in Oncogene

37

pp. 2676–2686

Full Text UEA Repository

(Article)

(Published)


Marlein, C. R., Zaitseva, L., Piddock, R. E., Robinson, S., Edwards, D., Shafat, M. S., Zhou, Z., Lawes, M., Bowles, K. M., Rushworth, S. A.

(2017)

NADPH oxidase-2 derived superoxide drives mitochondrial transfer from bone marrow stromal cells to leukemic blasts,

in Blood

130

(14)

pp. 1649-1660

Full Text UEA Repository

(Article)

(Published)


Piddock, R. E., Bowles, K. M., Rushworth, S. A.

(2017)

The Role of PI3K Isoforms in Regulating Bone Marrow Microenvironment Signaling Focusing on Acute Myeloid Leukemia and Multiple Myeloma,

in Cancers

9

(4)

article no. 29

Full Text UEA Repository

(Article)

(Published)


Piddock, R. E., Loughran, N., Marlein, C. R., Robinson, S. D., Edwards, D. R., Yu, S., Pillinger, G. E., Zhou, Z., Zaitseva, L., Auger, M. J., Rushworth, S. A., Bowles, K. M.

(2017)

PI3Kδ and PI3Kγ isoforms have distinct functions in regulating pro-tumoural signalling in the multiple myeloma microenvironment,

in Blood Cancer Journal

7

(3)

article no. e539

Full Text UEA Repository

(Article)

(Published)


Shafat, M. S., Oellerich, T., Mohr, S., Robinson, S. D., Edwards, D. R., Marlein, C. R., Piddock, R. E., Fenech, M., Zaitseva, L., Abdul-Aziz, A., Turner, J., Watkins, J. A., Lawes, M., Bowles, K. M., Rushworth, S. A.

(2017)

Leukemic blasts program bone marrow adipocytes to generate a protumoral microenvironment,

in Blood

129

(10)

pp. 1320-1332

Full Text UEA Repository

(Article)

(Published)


Pillinger, G., Loughran, N. V., Piddock, R. E., Shafat, M. S., Zaitseva, L., Abdul-Aziz, A., Lawes, M. J., Bowles, K. M., Rushworth, S. A.

(2016)

Targeting PI3Kδ and PI3Kγ signalling disrupts human AML survival and bone marrow stromal cell mediated protection,

in Oncotarget

7

(26)

pp. 39784-39795

Full Text UEA Repository

(Article)

(Published)


Rushworth, S., Pillinger, G., Abdul-Aziz, A., Piddock, R., Shafat, M. S., Murray, M. Y., Zaitseva, L., Lawes, M. J., MacEwan, D. J., Bowles, K. M.

(2015)

Activity of Bruton's tyrosine-kinase inhibitor ibrutinib in patients with CD117-positive acute myeloid leukaemia: a mechanistic study using patient-derived blast cells,

in The Lancet Haematology

2

(5)

pp. e204-e211

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(Article)

(Published)