All Publications

Abdul-Aziz, A. M., Shafat, M. S., Sun, Y., Marlein, C. R., Piddock, R. E., Robinson, S. D., Edwards, D. R., Zhou, Z., Collins, A., Bowles, K. M., Rushworth, S. A.

(2018)

HIF1α drives chemokine factor pro-tumoral signaling pathways in acute myeloid leukemia,

in Oncogene

37

pp. 2676–2686

Full Text UEA Repository

(Article)

(Published)


Marlein, C. R., Zaitseva, L., Piddock, R. E., Robinson, S., Edwards, D., Shafat, M. S., Zhou, Z., Lawes, M., Bowles, K. M., Rushworth, S. A.

(2017)

NADPH oxidase-2 derived superoxide drives mitochondrial transfer from bone marrow stromal cells to leukemic blasts,

in Blood

130

(14)

pp. 1649-1660

Full Text UEA Repository

(Article)

(Published)


Shafat, M. S., Gnaneswaran, B., Bowles, K. M., Rushworth, S. A.

(2017)

The bone marrow microenvironment – Home of the leukemic blasts,

in Blood Reviews

31

(5)

pp. 277–286

Full Text UEA Repository

(Article)

(Published)


Chandran, S., Watkins, J., Abdul‐Aziz, A., Shafat, M., Calvert, P. A., Bowles, K. M., Flather, M. D., Rushworth, S. A., Ryding, A. D.

(2017)

Inflammatory Differences in Plaque Erosion and Rupture in Patients With ST‐Segment Elevation Myocardial Infarction,

in Journal of the American Heart Association

6

(5)

article no. e005868

Full Text UEA Repository

(Article)

(Published)


Shafat, M. S., Oellerich, T., Mohr, S., Robinson, S. D., Edwards, D. R., Marlein, C. R., Piddock, R. E., Fenech, M., Zaitseva, L., Abdul-Aziz, A., Turner, J., Watkins, J. A., Lawes, M., Bowles, K. M., Rushworth, S. A.

(2017)

Leukemic blasts program bone marrow adipocytes to generate a protumoral microenvironment,

in Blood

129

(10)

pp. 1320-1332

Full Text UEA Repository

(Article)

(Published)


Abdul-Aziz, A., Shafat, M., Mehta, T., Di Palma, F., Lawes, M., Rushworth, S. A., Bowles, K.

(2017)

MIF-induced stromal PKCβ/IL8 is essential in human acute myeloid leukemia,

in Cancer Research

77

(2)

pp. 303-311

Full Text UEA Repository

(Article)

(Published)


Pillinger, G., Loughran, N. V., Piddock, R. E., Shafat, M. S., Zaitseva, L., Abdul-Aziz, A., Lawes, M. J., Bowles, K. M., Rushworth, S. A.

(2016)

Targeting PI3Kδ and PI3Kγ signalling disrupts human AML survival and bone marrow stromal cell mediated protection,

in Oncotarget

7

(26)

pp. 39784-39795

Full Text UEA Repository

(Article)

(Published)


Rushworth, S., Pillinger, G., Abdul-Aziz, A., Piddock, R., Shafat, M. S., Murray, M. Y., Zaitseva, L., Lawes, M. J., MacEwan, D. J., Bowles, K. M.

(2015)

Activity of Bruton's tyrosine-kinase inhibitor ibrutinib in patients with CD117-positive acute myeloid leukaemia: a mechanistic study using patient-derived blast cells,

in The Lancet Haematology

2

(5)

pp. e204-e211

Full Text UEA Repository

(Article)

(Published)


Zaitseva, L., Murray, M. Y., Shafat, M. S., Lawes, M. J., MacEwan, D. J., Bowles, K. M., Rushworth, S. A.

(2014)

Ibrutinib inhibits SDF1/CXCR4 mediated migration in AML,

in Oncotarget

5

(20)

pp. 9930-9938

Full Text UEA Repository

(Article)

(Published)