Clinical Efficacy of Functional Strength Training Clinical Efficacy of Functional Strength Training

Fast Indicate is the acronym for Clinical Efficacy of Functional Strength Training for upper limb motor recovery early after stoke: neural correlates and prognostic indicators.

Weakness of the arm and hand after stroke affects peoples' everyday lives and their capacity for independent living. Some treatments may be beneficial but this largely depends on a patient's ability to participate actively in repetitive practice of everyday (functional) tasks. Patients with substantial weakness may not be able to do this.

Hypothesis

Functional Strength Training plus Conventional Physical Therapy (FST+CPT) enhances upper limb motor recovery early after stroke more than Movement Performance Therapy plus CPT (MPT+CPT).

Aims

To determine:

  • The relative efficacy of FST+CPT and MPT+CPT.
  • The neural correlates of improvement in response to FST+CPT and MPT+CPT.
  • Whether any one or combination of baseline measures predict improvement in motor function in response to FST+CPT or MPT+CPT.
  • Estimate cost-effectiveness to inform a subsequent definitive clinical trial.

Funding

VM Pomeroy, NS Ward, H Johansen-Berg, P van Vliet, JH Burridge, S Hunter, R Lemon, J Rothwell, CJ Weir, J Norrie, A Wing, GR Barton.

Clinical efficacy of functional strength training for upper limb motor recovery early after stroke: neural correlates and prognostic indicators. Efficacy and Mechanisms Evaluation Programme (The NIHR Evaluation, Trials and Studies Coordinating Centre (NETSCC), based at the University of Southampton, manages evaluation research programmes and activities for the NIHR).

3 years from January 2012, £1,231,854.00

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