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Adhering to HIV treatment during adolescence: a multi method qualitative study in Uganda

DEV Key Contact: Janet Seeley
Project Dates: 2011 - 2014
Project Status: Current


Embedded within an international clinical randomised control trial (RCT), the study involves qualitative researchers from Uganda and the UK. The RCT (with JCRC in Uganda) is testing a new administration of HIV treatment for adolescents, known as short cycle therapy, in which young people take their treatment for five days and then have two days off at the weekend. This qualitative study explores the contextual barriers and facilitators to adherence, the acceptability of the therapy as an adherence strategy to young people and their experience of taking part in a trial. 

Status: Emerging results confirm the findings of other studies that suggest that the transition from adolescent to adulthood is a particularly difficult time for young people on ART, and support is often needed as they manage the emotional and physical changes that come with puberty while becoming a young adult in a paediatric clinic setting.  This is an area we plan to explore in more depth in a new project.

Major issues/challenges: Because of delays with the implementation of the trial (not with the social science component) the data collection will now be completed in mid 2014.  The ESRC has granted a no-cost extension.

Collaborators: Prof Tim Rhodes (LSHTM), Dr Sarah Bernays (LSHTM)

Uganda Projects leaders: Flavia Zalwango, with Dr Rwamahe Rutakumwa and Dr Godfrey Siu