Commercial long acting pharmaceutical formulations have been developed to fulfil clinical needs, of improving both patient adherence and long-term therapeutic outcomes [1-3]. Typical examples of such products can be found for delivering contraceptive and anti-psychotic drugs.
This fully funded PhD studentship in cooperation with Janssen will develop a new formulation platform addressing a number of drawbacks of the currently available formulation options including cost (both or production and excipient materials), duration of action, ease of manufacture and hydrolytic stability.
The new formulation platform will enable the engineering of novel materials that exhibit suitable phase transformation from injectable liquids to semisolid depots after deposition in the body.
The student will work in the state-of-the-art drug delivery lab at the School of Pharmacy and receive excellent training on advanced materials sciences research and transferable skills to ensure they can build a successful career beyond their PhD. The project is a close research collaboration with Janssen.
The student will have a fixed period of exchange embedded within Janssen's R&D team and gain insights into industrial research and product development.