Plants need to respond to the environment in order to adapt and grow. Plants often modify the concentration of calcium ions in their cells in response to different environmental stimuli and stresses . These changes in cellular calcium concentration trigger many downstream responses, including the re-programming of gene expression. Calcium signalling pathways are therefore essential for plants to respond and adapt to environmental stimuli and stresses.
Higher plants, such as the model plant Arabidopsis thaliana, have extensive networks of proteins associated with calcium signalling pathways, and traditional genetic studies have identified mutants in components of these pathways. However, genetic redundancy is often observed and this has hindered the further study of these signalling pathways. Recent genomic analyses have revealed that the gene families encoding components of calcium signalling pathways are considerably smaller in basal land plant species, e.g. the liverwort Marchantia polymorpha . The study of these pathways in basal land plants will therefore offer unique insights and understandings into calcium signalling pathways in higher plants, and may identify new potential targets that could be manipulated to improve stress tolerance in crop species.
This PhD project will undertake a multi-disciplinary approach combining molecular genetics, computational analyses and biochemistry to dissect calcium signalling in the basal land plant Marchantia polymorpha.
The Norwich Research Park Biosciences Doctoral Training Partnership (NRPDTP) is open to the UK and international candidates for entry in October 2022 and offers postgraduates the opportunity to undertake a 4-year PhD research project whilst enhancing professional development and research skills through a comprehensive training programme. You will join a vibrant community of world-leading researchers. All NRPDTP students undertake a three-month professional internship placement (PIPS) during their study. The placement offers exciting and invaluable work experience designed to enhance professional development. Full support and advice will be provided by our Professional Internship team. Students with, or expecting to attain, at least an upper second class honours degree, or equivalent, are invited to apply.
This project has been shortlisted for funding by the NRPDTP programme. Shortlisted applicants will be interviewed on Tuesday 25th January, Wednesday 26th January and Thursday 27th January 2022.
You can visit the Norwich Research Park Biosciences Doctoral Training Partnership pages for further information on eligibility and the application process.
Our partners value diverse and inclusive work environments that are positive and supportive. Students are selected for admission without regard to gender, marital or civil partnership status, disability, race, nationality, ethnic origin, religion or belief, sexual orientation, age or social background.