Biography

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Stephen Meech has been at UEA since 1994. His research is focused on understanding ultrafast dynamics of complex condensed phase systems and interfaces. He maintains a number of national and international research collaborations which facilitates the application of ultrafast methods to some of the most interesting and challenging problems. Prior to joining UEA he was an Inoue Foundation fellow at IMS Japan and an EPSRC fellow at The University of Groningen, The Netherlands. He has held two JSPS fellowships in Japan and was a visiting researcher at RIKEN Tokyo.

Selected Publications

Brust, Richard, Lukacs, Andras, Haigney, Allison, Addison, Kiri, Gil, Agnieszka, Towrie, Michael, Clark, Ian P., Greetham, Gregory M., Tonge, Peter J. and Meech, Stephen R.
Proteins in Action: Femtosecond to Millisecond Structural Dynamics of a Photoactive Flavoprotein.
Journal of the American Chemical Society, 2013, 135 (43). pp. 16168-16174. ISSN 0002-7863

Lukacs, Andras, Haigney, Allison, Brust, Richard, Addison, Kiri, Towrie, Michael, Greetham, Gregory M., Jones, Garth A., Miyawaki, Atsushi, Tonge, Peter J. and Meech, Stephen R.
Protein Photochromism Observed by Ultrafast Vibrational Spectroscopy.
The Journal of Physical Chemistry B, 2013, 117 (40). pp. 11954-11959. ISSN 1520-6106

Conyard, J, Addison, K, Heisler, IA, Cnossen, A, Browne, WR, Feringa, BL and Meech, SR
Ultrafast dynamics in the power stroke of a molecular rotary motor.
Nature Chemistry, 2012, 4 (7). pp. 547-551. ISSN 1755-4330

Mazur, K, Heisler, IA and Meech, SR
THz Spectra and Dynamics of Aqueous Solutions Studied by the Ultrafast Optical Kerr Effect.
The Journal of Physical Chemistry B, 2011, 115 (11). pp. 2563-2573. ISSN 1520-6106

Heisler, IA and Meech, SR
Low Frequency Modes of Aqueous Alkali Halide Solutions: Glimpsing the Hydrogen Bond Vibration.
Science, 2010, 327, 857 – 860.

Kondo, Minako, Heisler, Ismael, Stoner-Ma, Deborah, Tonge, Peter J. and Meech, Stephen R.
Ultrafast Dynamics of Protein Proton Transfer on Short Hydrogen Bond Potential Energy Surfaces: S65T/H148D GFP.
Journal of the American Chemical Society, 2010, 132 (5). pp. 1452-1453.

Highlighted Publications

See All

Lukacs, A., Brust, R., Haigney, A., Laptenok, S. P., Addison, K., Gil, A., Towrie, M., Greetham, G. M., Tonge, P. J., Meech, S. R.

(2014)

BLUF Domain Function Does Not Require a Metastable Radical Intermediate State,

in Journal of the American Chemical Society

136.

pp. 4605-4615

Full Text UEA Repository

(Article)

(Published)


Conyard, J., Cnossen, A., Browne, W., Feringa, B. L., Meech, S.

(2014)

Chemically Optimising Operational Efficiency of Molecular Rotary Motors,

in Journal of the American Chemical Society

136.

pp. 9692-9700

Full Text UEA Repository

(Article)

(Published)


Brust, R., Lukacs, A., Haigney, A., Addison, K., Gil, A., Towrie, M., Clark, I. P., Greetham, G. M., Tonge, P. J., Meech, S. R.

(2013)

Proteins in Action: Femtosecond to Millisecond Structural Dynamics of a Photoactive Flavoprotein,

in Journal of the American Chemical Society

135.

pp. 16168-16174

Full Text UEA Repository

(Article)

(Published)


Conyard, J., Addison, K., Heisler, I., Cnossen, A., Browne, W., Feringa, B., Meech, S.

(2012)

Ultrafast dynamics in the power stroke of a molecular rotary motor,

in Nature Chemistry

4.

pp. 547-551

Full Text UEA Repository

(Article)

(Published)


Mazur, K., Heisler, I., Meech, S.

(2012)

Water Dynamics at Protein Interfaces: Ultrafast Optical Kerr Effect Study,

in The Journal of Physical Chemistry A

116.

pp. 2678-2685

Full Text UEA Repository

(Article)

(Published)


Heisler, I., Meech, S.

(2010)

Low-Frequency Modes of Aqueous Alkali Halide Solutions: Glimpsing the Hydrogen Bonding Vibration,

in Science

327.

pp. 857-860

Full Text UEA Repository

(Article)

(Published)


All Publications

See Highlights
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Heisler, I., Mazur, K., Meech, S.

(2017)

Raman vibrational dynamics of hydrated ions in the low-frequency spectral region,

in Journal of Molecular Liquids

228

pp. 45–53

Full Text UEA Repository

(Article)

(Published)


Gil, A. A., Laptenok, S. P., French, J. B., Iuliano, J. N., Lukacs, A., Hall, C. R., Sazanovich, I. V., Greetham, G. M., Bacher, A., Illarionov, B., Fischer, M., Tonge, P. J., Meech, S. R.

(2017)

Femtosecond To Millisecond Dynamics Of Light Induced Allostery In The Avena Sativa Lov Domain,

in Journal of Physical Chemistry B

121

(5)

pp. 1010–1019

Full Text UEA Repository

(Article)

(Published)


Valduga De Almeida Camargo, F., Grimmelsmann, L., Anderson, H. L., Meech, S. R., Heisler, I. A.

(2017)

Resolving vibrational from electronic coherences in two-dimensional electronic spectroscopy: The role of the laser spectrum,

in Physical Review Letters

118

(3)

article no. 033001

UEA Repository

(Article)

(Published)


Tay, J., Parks, M. A., Addison, K., Chan, Y., Zhang, L., Hailes, H. C., Bulman Page, P. C., Meech, S. R., Blancafort, L., Fielding, H. H.

(2017)

The Effect of Conjugation on the Competition Between Internal Conversion and Electron Detachment: A Comparison Between Green Fluorescent and Red Kaede Protein Chromophores,

in The Journal of Physical Chemistry Letters

8

(1)

pp. 765–771

Full Text UEA Repository

(Article)

(Published)


Conyard, J., Stacko, P., Chen, J., McDonagh, S., Hall, C. R., Laptenok, S. P., Browne, W. R., Feringa, B. L., Meech, S. R.

(2017)

Ultrafast excited state dynamics in a molecular motor: Coupling of motor length to medium viscosity,

in Journal of Physical Chemistry A

121

(10)

pp. 2138–2150

Full Text UEA Repository

(Article)

(Published)


Hall, C. R., Heisler, I., Jones, G., Frost, J., Gil, A. A., Tonge, P. J., Meech, S. R.

(2017)

Femtosecond Stimulated Raman Study of the Photoactive Flavoprotein AppABLUF,

in Chemical Physics Letters

Full Text UEA Repository

(Article)

(E-pub ahead of print)


Hall, C. R., Conyard, J., Heisler, I. A., Jones, G. A., Frost, J., Browne, W. R., Feringa, B. L., Meech, S. R.

(2017)

Ultrafast dynamics in light driven molecular rotary motors probed by femtosecond stimulated raman scattering,

in Journal of the American Chemical Society

Full Text UEA Repository

(Article)

(E-pub ahead of print)


Meech, S., Laptenok, S., Lukacs, A., Haigney, A., Zhao, R., Tonge, P. J., Gil, A., Brust, R., Towrie, M., Greetham, G. M.

(2016)

The Mechanism of the AppABLUF Photocycle Probed by Site-Specific Incorporation of Fluorotyrosine Residues: The Effect of the Y21 pKa on the Forward and Reverse Ground State Reactions,

in Journal of the American Chemical Society

138

(3)

pp. 926–935

Full Text UEA Repository

(Article)

(Published)


Camargo, F. V. A., Hall, C. R., Anderson, H. L., Meech, S. R., Heisler, I. A.

(2016)

Time Resolved Structural Dynamics of Butadiyne-Linked Porphyrin Dimers,

in Structural Dynamics

3

article no. 023608

Full Text UEA Repository

(Article)

(Published)


Laptenok, S., Conyard, J., Bulman Page, P., Chan, Y., Jaffrey, S., You, M., Meech, S.

(2016)

Photoacid behaviour in a fluorinated green fluorescent protein chromophore: Ultrafast formation of anion and zwitterion states,

in Chemical Science

7

(9)

pp. 5747-5752

Full Text UEA Repository

(Article)

(Published)


Laptenok, S., Lukacs, A., Brust, R., Haigney, A., Gil, A., Towrie, M., Greetham, G. M., Tonge, P. J., Meech, S.

(2015)

Electron Transfer Quenching in Light Adapted and Mutant Forms of the AppA BLUF Domain,

in Faraday Discussions

177

pp. 293-311

Full Text UEA Repository

(Article)

(Published)


Valduga De Almeida Camargo, F., Anderson, H., Meech, S., Heisler, I.

(2015)

Full characterization of vibrational coherence in a porphyrin chromophore by two-dimensional electronic spectroscopy,

in The Journal of Physical Chemistry A

119

(1)

pp. 95–101

Full Text UEA Repository

(Article)

(Published)


Palombo, F., Heisler, I., Hribar-Lee, B., Meech, S.

(2015)

Tuning the Hydrophobic Interaction: Ultrafast Optical Kerr Effect Study of Aqueous Ionene Solutions,

in The Journal of Physical Chemistry A

119

(29)

pp. 8900–8908

Full Text UEA Repository

(Article)

(Published)


Laptenok, S., Lukacs, A., Gil, A., Brust, R., Sazanovich, I., Greetham, G. M., Tonge, P. J., Meech, S.

(2015)

Complete Proton Transfer Cycle in GFP and Its T203V and S205V Mutants,

in Angewandte Chemie International Edition

127

(32)

pp. 9435–9439

Full Text UEA Repository

(Article)

(Published)


Moca, R., Meech, S., Heisler, I.

(2015)

Two-Dimensional Electronic Spectroscopy of Chlorophyll a: Solvent Dependent Spectral Evolution,

in The Journal of Physical Chemistry B

119

(27)

pp. 8623-8630

Full Text UEA Repository

(Article)

(Published)


Camargo, F. V. A., Heisler, I. V. A., Anderson, H. L., Meech, S. R.

(2015)

Time-Resolved Twisting Dynamics in a Porphyrin Dimer Characterized by Two-Dimensional Electronic Spectroscopy,

in The Journal of Physical Chemistry B

119

(46)

pp. 14660-14667

Full Text UEA Repository

(Article)

(Published)


Brust, R., Haigney, A., Lukacs, A., Gil, A., Hossain, S., Addison, K., Lai, C., Towrie, M., Greetham, G. M., Clark, I. P., Illarionov, B., Bacher, A., Kim, R., Fischer, M., Simmerling, C., Meech, S. R., Tonge, P. J.

(2014)

Ultrafast Structural Dynamics of BlsA, a Photoreceptor from the Pathogenic Bacterium Acinetobacter baumannii,

in The Journal of Physical Chemistry Letters

5

(1)

pp. 220-224

Full Text UEA Repository

(Article)

(Published)


Lukacs, A., Brust, R., Haigney, A., Laptenok, S. P., Addison, K., Gil, A., Towrie, M., Greetham, G. M., Tonge, P. J., Meech, S. R.

(2014)

BLUF Domain Function Does Not Require a Metastable Radical Intermediate State,

in Journal of the American Chemical Society

136

(12)

pp. 4605-4615

Full Text UEA Repository

(Article)

(Published)


Conyard, J., Heisler, I. A., Browne, W. R., Feringa, B. L., Amirjalayer, S., Buma, W. J., Woutersen, S., Meech, S. R.

(2014)

Ultrafast Excited State Dynamics in 9,9′-Bifluorenylidene,

in The Journal of Physical Chemistry A

118

(31)

pp. 5961-5968

Full Text UEA Repository

(Article)

(Published)


Conyard, J., Cnossen, A., Browne, W., Feringa, B. L., Meech, S.

(2014)

Chemically Optimising Operational Efficiency of Molecular Rotary Motors,

in Journal of the American Chemical Society

136

(27)

pp. 9692-9700

Full Text UEA Repository

(Article)

(Published)


<- Page 1 of 5 ->

Key Research Interests

My principal research interest is in the development and application of ultrafast methods in spectroscopy. Current methods include ultrafast two-dimensional spectroscopy (with Ismael Heisler, UEA) ultrafast (sub 50 fs) fluorescence up-conversion, transient absorption and optical Kerr effect spectroscopy. These are applied to investigate a number of complex systems including:  coupled chromophore arrays; molecular motors; photoactive fluorescent proteins; blue light sensing proteins; molecular structure and dynamics in aqueous solution.

Research Group Membership

Senior Research Associates

  • Dr Christopher Hall - christopher.hall@uea.ac.uk 
  • Dr Jamie Conyard - j.conyard@uea.ac.uk


PhD

  • Franco Valduga De Almeida 

 
Project Students

  • Sophie McDonagh


Former Members (* Phd Student, last known position - updates and links welcome)

  • Dr Siarhei Laptenok (Research Fellow, King Abdullah University of Science and Technology)
  • Dr Kiri Addison* (cyber data specialist, civil service)
  • Dr. Kamila Mazur* (national Instruments, USA)
  • Dr. Jamie Conyard* (Post-doc, UEA, see above)
  • Dr. Rui-Kun Zhao* (Teaching Fellow South Bank University)
  • Prof. Andras Lukcas - (Prof of Biophysics, University Pec) andras.lukacs@aok.pte.hu
  • Dr. Minako Kondo* - (Lecturer, Ochanomizu University, kondo.minako@ocha.ac.jp)
  • Dr. Jerome Nappa  
  • Dr. James Rice - (Lecturer in Physics University College Dublin) james.rice@ucd.ie
  • Dr. Jesus Garduno-Mejia (Prof in Physics Universidad Nacional Autónoma de Méxicojesus.garduno@ccadet.unam.mx
  • Dr Mike Hope*  
  • Dr Michael Higlett* (Scientist Health Protection Agency) michael.higlett@hpa.org.uk
  • M.Sc. Lesley Jaggard  
  • Dr. James Mann*
  • Dr Neil Hunt (Reader in Physics, Strathclyde University)
  • Dr Andy Jaye* (Post doc Stony Brook University)
  • Dr Daren Burke* (Post doc Univeristy College London)
  • Dr Tomas Vondrak (Senior Research Associate University Leeds)
  • Dr Naomi Webber* (Government Relations, Lewis Burke Associates, Washington, Naomi@lewis-burke.com))
  • Dr Konstantin Litvinenko (Senior Research Associate, University of Surrey)
  • Dr Neil Smith* (Software Development and Training, Qinetiq)
  • Dr Shujie Lin (Institute of Optical Science, Toronto)
  • Dr Rob Kidd* (Analyst, Astra Zeneca, Cambridge)
  • Dr Michael Morgenthaler* (*at Heriot Watt, Strathclyde Police)

Dr. Ismael Heisler.
 

 

Dr. Andras Lukcas.

 

PhD student Kamila working with Cavity-Dumped laser.

 

PhD student Leo.



PhD student Jamie.



PhD student Kiri.



PhD student Clare.

Teaching Interests

I teach courses across the spectrum of physical chemistry and chemical physics, from first to Masters years.

External Activities and Indicators of Esteem

2011 - European Editor Journal of Photochemistry and Photobiology A Chemistry.

Administrative Posts

Chair, School Athena Swan Panel (ex-officio school executive board).