Career History

Since completion of my PhD in 1999 I have undertaken postdoctoral research roles at the Medical College of Wisconsin, USA, the Dunn Human Nutrition Unit in Cambridge and the BBSRC Institute of Food Research in Norwich. I joined the Norwich Medical School at UEA as a Senior Research Associate in 2007, working with Professor Fairweather-Tait on selenium and prostate cancer research and subsequently joined Professor Colin Cooper's research team in 2012 to pursue research on biomarkers of prostate cancer.

Research interests

  • Prostate cancer biomarkers

All Publications

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Ross-Adams, H., Lamb, A., Dunning, M., Halim, S., Lindberg, J., Massie, C., Egevad, L., Russell, R., Ramos-Montoya, A., Vowler, S., Sharma, N., Kay, J., Whitaker, H., Clark, J., Hurst, R., Gnanapragasam, V., Shah, N., Warren, A., Cooper, C., Lynch, A., Stark, R., Mills, I., Groenberg, H., Neal, D.

(2015)

Integration of copy number and transcriptomics provides risk stratification in prostate cancer: A discovery and validation cohort study,

in EBioMedicine

2

(9)

pp. 1133–1144

Full Text UEA Repository

(Article)

(Published)


Gibson, R. S., Wawer, A. A., Fairweather-Tait, S. J., Hurst, R., Young, S. D., Broadley, M. R., Chilimba, A. D., Ander, E. L., Watts, M. J., Kalimbira, A., Bailey, K. B., Siyame, E. W.

(2015)

Dietary iron intakes based on food composition data may underestimate the contribution of potentially exchangeable contaminant iron from soil,

in Journal of Food Composition and Analysis

40

pp. 19-23

Full Text UEA Repository

(Article)

(Published)


Cooper, C., Eeles, R. A., Wedge, D. C., Van Loo, P., Gundem, G., Alexandrov, L., Kreymer, B., Butler, A., Lynch, A., Edwards, S. E., Camacho, N., Massie, C. E., Kote-Jarai, Z., Dennis, N., Merson, S., Leongamornlert, D. A., Zamora, J., Kay, J., Luxton, H. J., Corbishley, C., Thomas, S., Nik-Zainal, S., O'Meara, S., Matthews, L., Clark, J., Hurst, R., Mithen (IFR), R., Bristow (Ontario Cancer Inst. CA), R., Boutros, P. C., Fraser, M., Cooke, S., Raine, K., Jones, D., Menzies, A., Stebbings, L., Hinton, J., Teague, J., Mclaren, S., Mudie, L., Hardy, C., Anderson, E., Joseph, O., Goody, V., Robinson, B., Maddison, M., Gamble, S., Greenman, C., Berney, D., Hazell, S., Livni, N., Fisher, C., Ogden, C., Kumar, P., Thompson, A., Woodhouse, C. J., Nicol, D., Mayer, E., Dudderidge, T., Shah, N., Gnanapragasam, V., Voet, T., Campbell, P., Futreal, P. A., Easton, D. F., Warren, A. Y., Foster, C. S., Stratton, M. R., Whitaker, H. C., Mcdermott, U., Brewer, D., Neal, D. E.

(2015)

Analysis of the genetic phylogeny of multifocal prostate cancer identifies multiple independent clonal expansions in neoplastic and morphologically normal prostate tissue,

in Nature Genetics

47

pp. 367–372

Full Text

(Letter)

(Published)


Manson-Bahr, D., Ball, R., Gundem, G., Mills, R., Rochester, M., Goody, V., O'Meara, S., Flather, M., Keeling, M., Yazbek Hanna, M., Hurst, R., Curley, H., Clark, J., Brewer, D., Mcdermott, U., Cooper, C.

(2015)

Mutation detection in formalin-fixed prostate cancer biopsies taken at the time of diagnosis using next generation DNA sequencing,

in Journal of Clinical Pathology

68

pp. 212-217

Full Text UEA Repository

(Article)

(Published)


Joy, E. J. M., Ander, E. L., Young, S. D., Black, C. R., Watts, M. J., Chilimba, A. D. C., Chilima, B., Siyame, E. W. P., Kalimbira, A. A., Hurst, R., Fairweather-Tait, S. J., Stein, A. J., Gibson, R. S., White, P. J., Broadley, M. R.

(2014)

Dietary mineral supplies in Africa,

in Physiologia Plantarum

151

(3)

pp. 208-229

Full Text UEA Repository

(Article)

(Published)


Fairweather-Tait, S. J., Guile, G. R., Valdes, A. M., Wawer, A. A., Hurst, R., Skinner, J., Macgregor, A. J.

(2013)

The contribution of diet and genotype to iron status in women: a classical twin study,

in PLoS ONE

8

(12)

article no. e83047

Full Text UEA Repository

(Article)

(Published)


Collings, R., Harvey, L. J., Hooper, L., Hurst, R., Brown, T. J., Ansett, J., King, M., Fairweather-Tait, S. J.

(2013)

The absorption of iron from whole diets: a systematic review,

in American Journal of Clinical Nutrition

98

(1)

pp. 65-81

Full Text UEA Repository

(Article)

(Published)


Hurst, R., Collings, R., Harvey, L. J., King, M., Hooper, L., Bouwman, J., Gurinovic, M., Fairweather-Tait, S. J.

(2013)

EURRECA-Estimating selenium requirements for deriving dietary reference values,

in Critical Reviews in Food Science and Nutrition

53

(10)

pp. 1077-96

Full Text UEA Repository

(Article)

(Published)


Harvey, L. J., Berti, C., Casgrain, A., Cetin, I., Collings, R., Gurinovic, M., Hermoso, M., Hooper, L., Hurst, R., Koletzko, B., Ngo, J., Viñas, B. R., Vollhardt, C., Vucic, V., Fairweather-Tait, S. J.

(2013)

EURRECA-Estimating iron requirements for deriving dietary reference values,

in Critical Reviews in Food Science and Nutrition

53

(10)

pp. 1064-76

Full Text UEA Repository

(Article)

(Published)


Hurst, R., Siyame, E. W. P., Young, S. D., Chilimba, A. D. C., Joy, E. J. M., Black, C. R., Ander, E. L., Watts, M. J., Chilima, B., Gondwe, J., Kang'ombe, D., Stein, A. J., Fairweather-Tait, S. J., Gibson, R. S., Kalimbira, A. A., Broadley, M. R.

(2013)

Soil-type influences human selenium status and underlies widespread selenium deficiency risks in Malawi,

in Scientific Reports

3

article no. 1425

Full Text UEA Repository

(Article)

(Published)


Siyame, E. W. P., Hurst, R., Wawer, A. A., Young, S. D., Broadley, M. R., Chilimba, A. D. C., Ander, L. E., Watts, M. J., Chilima, B., Gondwe, J., Kang'ombe, D., Kalimbira, A., Fairweather-Tait, S. J., Bailey, K. B., Gibson, R. S.

(2013)

A high prevalence of zinc- but not iron-deficiency among women in rural Malawi: a cross-sectional study,

in International Journal for Vitamin and Nutrition Research

83

(3)

pp. 176-87

Full Text UEA Repository

(Article)

(Published)


Hurst, R., Hooper, L., Norat, T., Lau, R., Aune, D., Greenwood, D. C., Vieira, R., Collings, R., Harvey, L. J., Sterne, J. A. C., Beynon, R., Savović, J., Fairweather-Tait, S. J.

(2012)

Selenium and prostate cancer: systematic review and meta-analysis,

in American Journal of Clinical Nutrition

96

(1)

pp. 111-122

Full Text UEA Repository

(Article)

(Published)


Broadley, M. R., Chilimba, A. D. C., Joy, E. J. M., Young, S. D., Black, C. R., Ander, L. E., Watts, M. J., Hurst, R., Fairweather-Tait, S. J., White, P. J., Gibson, R. S.

(2012)

Dietary requirements for magnesium, but not calcium, are likely to be met in Malawi based on national food supply data,

in International Journal for Vitamin and Nutrition Research

82

(3)

pp. 192-9

Full Text UEA Repository

(Article)

(Published)


Hart, D. J., Fairweather-Tait, S. J., Broadley, M. R., Dickinson, S. J., Foot, I., Knott, P., McGrath, S. P., Mowat, H., Norman, K., Scott, P. R., Stroud, J. L., Tucker, M., White, P. J., Zhao, F. J., Hurst, R.

(2011)

Selenium concentration and speciation in biofortified flour and bread: Retention of selenium during grain biofortification, processing and production of Se-enriched food,

in Food Chemistry

126

(4)

pp. 1771-1778

Full Text UEA Repository

(Article)

(Published)


Fairweather-Tait, S. J., Bao, Y., Broadley, M. R., Collings, R., Ford, D., Hesketh, J. E., Hurst, R.

(2011)

Selenium in human health and disease,

in Antioxidants & Redox Signaling

14

(7)

pp. 1337-1383

Full Text UEA Repository

(Article)

(Published)


Goldson, A. J., Fairweather-Tait, S. J., Armah, C. N., Bao, Y., Broadley, M. R., Dainty, J. R., Furniss, C., Hart, D. J., Teucher, B., Hurst, R.

(2011)

Effects of Selenium Supplementation on Selenoprotein Gene Expression and Response to Influenza Vaccine Challenge: A Randomised Controlled Trial,

in PLoS ONE

6

(3)

article no. e14771

Full Text UEA Repository

(Article)

(Published)


Hurst, R., Young, S., Siyame, E., Kalimbira, A., Gibson, R., Fairweather-Tait, S., Chilima, B., Gondwe, J., Ander, L., Watts, M., Chilimba, A., Broadley, M.

(2011)

Selenium intake and nutritional status in Malawi: implications for health,

in Journal of Trace Elements in Medicine and Biology

26S

pp. 18

UEA Repository

(Article)

(Published)


Fairweather-Tait, S. J., Collings, R., Hurst, R.

(2010)

Selenium bioavailability: current knowledge and future research requirements,

in American Journal of Clinical Nutrition

91

(5)

pp. 1484S-1491S

Full Text UEA Repository

(Article)

(Published)


Hurst, R., Armah, C. N., Dainty, J. R., Hart, D. J., Teucher, B., Goldson, A. J., Broadley, M. R., Motley, A. K., Fairweather-Tait, S. J.

(2010)

Establishing optimal selenium status: results of a randomized, double-blind, placebo-controlled trial,

in American Journal of Clinical Nutrition

91

(4)

pp. 923-931

Full Text UEA Repository

(Article)

(Published)


Broadley, M., Alcock, J., Alford, J., Cartwright, P., Foot, I., Fairweather-Tait, S., Hart, D., Hurst, R., Knott, P., McGrath, S., Meacham, M., Norman, K., Mowatt, H., Scott, P., Stroud, J., Tovey, M., Tucker, M., White, P., Young, S., Zhao, F.

(2010)

Selenium biofortification of high-yielding winter wheat (Triticum aestivum L.) by liquid or granular Se fertilisation,

in Plant and Soil

332

pp. 5-18

UEA Repository

(Article)

(Published)


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Key Research Interests

I am a member of the Cancer Genetics team in the School of Biological Sciences and Norwich Medical School working with Professor Colin Cooper, Dr Jeremy Clark and colleagues on prostate cancer biomarkers.