Biography

Ben Miller is the Eastern ARC Fellow in Synthetic Biology at the University of East Anglia. Ben is a molecular biologist with an interest in calcium signalling pathways and synthetic biology in plants. His research is focussed on how plants use calcium as a second messenger to respond and adapt to the environment.

 

Career History

Eastern ARC Fellow in Synthetic Biology, University of East Anglia (2015 - Present)

Post-doctoral Scientist, John Innes Centre (2012 - 2015)

PhD, John Innes Centre (2012)

BSc, University of Durham (2008)

All Publications

Patron, N. J., Orzaez, D., Marillonnet, S., Warzecha, H., Matthewman, C., Youles, M., Raitskin, O., Leveau, A., Farré, G., Rogers, C., Smith, A., Hibberd, J., Webb, A. A. R., Locke, J., Schornack, S., Ajioka, J., Baulcombe, D. C., Zipfel, C., Kamoun, S., Jones, J. D. G., Kuhn, H., Robatzek, S., Van Esse, H. P., Sanders, D., Oldroyd, G., Martin, C., Field, R., O'Connor, S., Fox, S., Wulff, B., Miller, B., Breakspear, A., Radhakrishnan, G., Delaux, P., Loqué, D., Granell, A., Tissier, A., Shih, P., Brutnell, T. P., Quick, W. P., Rischer, H., Fraser, P. D., Aharoni, A., Raines, C., South, P. F., Ané, J., Hamberger, B. R., Langdale, J., Stougaard, J., Bouwmeester, H., Udvardi, M., Murray, J. A. H., Ntoukakis, V., Schäfer, P., Denby, K., Edwards, K. J., Osbourn, A., Haseloff, J.

(2015)

Standards for plant synthetic biology: a common syntax for exchange of DNA parts,

in New Phytologist

208

(1)

pp. 13-19

Full Text UEA Repository

(Article)

(Published)


Sun, J., Miller, J. B., Granqvist, E., Wiley-Kalil, A., Gobbato, E., Maillet, F., Cottaz, S., Samain, E., Venkateshwaran, M., Fort, S., Morris, R. J., Ané, J., Dénarié, J., Oldroyd, G. E. D.

(2015)

Activation of symbiosis signaling by arbuscular mycorrhizal fungi in legumes and rice,

in The Plant Cell

27

(3)

pp. 823-838

Full Text UEA Repository

(Article)

(Published)


Miller, J. B., Pratap, A., Miyahara, A., Zhou, L., Bornemann, S., Morris, R. J., Oldroyd, G. E. D.

(2013)

Calcium/Calmodulin-dependent protein kinase is negatively and positively regulated by calcium, providing a mechanism for decoding calcium responses during symbiosis signaling,

in The Plant Cell

25

(12)

pp. 5053-5066

Full Text UEA Repository

(Article)

(Published)


Routray, P., Miller, J. B., Du, L., Oldroyd, G., Poovaiah, B. W.

(2013)

Phosphorylation of S344 in the calmodulin-binding domain negatively affects CCaMK function during bacterial and fungal symbioses,

in The Plant Journal

76

(2)

pp. 287-96

Full Text UEA Repository

(Article)

(Published)


Gobbato, E., Marsh, J. F., Vernié, T., Wang, E., Maillet, F., Kim, J., Miller, J. B., Sun, J., Bano, S. A., Ratet, P., Mysore, K. S., Dénarié, J., Schultze, M., Oldroyd, G. E. D.

(2012)

A GRAS-type transcription factor with a specific function in mycorrhizal signaling,

in Current Biology

22

(23)

pp. 2236-2241

Full Text UEA Repository

(Article)

(Published)


Key Research Interests

Plants use calcium as a second messenger in signal transduction pathways associated with many different biological processes, for example during drought, salt or cold stress, and during interactions with pathogens or symbionts. These different stimuli are able to induce different calcium signals in plant cells, but it is unclear how these different calcium signals bring about further specific responses.

Many calcium-binding proteins have been identified in plants and most of these proteins possess EF-hand motifs which have been shown to directly bind calcium ions. We are interested in understanding how these calcium-binding proteins decode different calcium signals into specific signalling responses.

If you are interested in a postdoctoral position in our laboratory, please e-mail me directly to discuss possibilities. We are very interested in potential postdocs with a strong background in plant biology, synthetic biology or biochemistry. Applicants are encouraged to look for funding sources, including Wellcome Trust Postdoctoral Fellowships, Marie Curie Fellowships, Newton Fellowships and HFSP Fellowships

 

Current lab members

Maria Contreras Delgado (Eastern ARC funded PhD student)

Connor Tansley (BBSRC-DTP funded PhD student)