Career History

  • Since 2010 Professor of Developmental Biology
  • Reader in Developmental Biology, University of East Anglia, (2006 – 2010)
  • Senior Lecturer in Developmental Biology, University of East Anglia (2001-2006)
  • Wellcome Trust Career Development Fellow, University of Dundee (1997-2001)
  • Lecturer and Principal Investigator, University of Dundee (1996-1997)
  • MDA Postdoctoral Fellow, Harvard Medical School, Boston, USA (1994-1996)
  • HFSPO Postdoctoral Fellow, Harvard Medical School, Boston, USA (1992-1994)
  • Ph.D. - National Institute for Medical Research, MRC, Mill Hill, London (1992)
  • German Diploma - Biology, University of Heidelberg (1988)

 

ResearcherID 

http://www.researcherid.com/rid/E-2205-2011

All Publications

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Wang, G., Chen, E., Liang, C., Liang, J., Gao, L., Chuai, M., Munsterberg, A., Bao, Y., Cao, L., Yang, X.

(2018)

Atg7-Mediated Autophagy Is Involved in the Neural Crest Cell Generation in Chick Embryo,

in Molecular Neurobiology

55

(4)

pp. 3523–3536

Full Text UEA Repository

(Article)

(Published)


Ward, N., Green, D., Higgins, J., Dalmay, T., Munsterberg, A., Moxon, S., Wheeler, G.

(2018)

microRNAs associated with early neural crest development in Xenopus laevis,

in BMC Genomics

19

article no. 59

Full Text UEA Repository

(Article)

(Published)


Li, Y., Zhang, X., Wang, X., Wang, G., Chuai, M., Münsterberg, A., Yang, X.

(2017)

Robo signaling regulates the production of cranial neural crest cells,

in Experimental Cell Research

361

(1)

pp. 73-84

Full Text UEA Repository

(Article)

(Published)


Mok, G. F., Lozano-Velasco, E., Munsterberg, A.

(2017)

MicroRNAs in skeletal muscle development,

in Seminars in Cell & Developmental Biology

72

pp. 67-76

Full Text UEA Repository

(Article)

(Published)


Liu, P., Atkinson, S. J., Akbareian, S., Zhou, Z., Munsterberg, A., Robinson, S., Bao, Y.

(2017)

Sulforaphane exerts anti-angiogenesis effects against hepatocellular carcinoma through inhibition of STAT3/HIF-1α/VEGF signalling,

in Scientific Reports

7

article no. 12651

Full Text UEA Repository

(Article)

(Published)


Sanz-Ezquerro, J. J., Münsterberg, A. E., Stricker, S.

(2017)

Editorial: Signaling Pathways in Embryonic Development,

in Frontiers in Cell and Developmental Biology

5

article no. 76

Full Text UEA Repository

(Article)

(Published)


Saad, K., Otto, A., Theis, S., Kennerley, N., Munsterberg, A., Luke, G., Patel, K.

(2017)

Detailed expression profile of all six Glypicans and their modifying enzyme Notum during chick embryogenesis and their role in dorsal-ventral patterning of the neural tube,

in Gene

609

pp. 38-51

Full Text UEA Repository

(Article)

(Published)


Hatch, V., Marin Barba, M., Moxon, S., Ford, C., Ward, N., Tomlinson, M., Desanlis, I., Hendry, A., Hontelez, S., van Krujsbergen, I., Veenstra, G. J., Munsterberg, A., Wheeler, G.

(2016)

The positive transcriptional elongation factor (P-TEFb) is required for neural crest specification,

in Developmental Biology

416

(2)

pp. 361–372

Full Text UEA Repository

(Article)

(Published)


Münsterberg, A., Hoppler, S.

(2016)

WNT and BMP regulate roadblocks toward cardiomyocyte differentiation: lessons learned from embryos inform human stem cell differentiation,

in Stem Cell Investigation

3

article no. 33

Full Text

(Editorial)

(Published)


Giusti, J., Pinhal, D., Moxon, S., Lovaglio Campos, C., Munsterberg, A., Martins, C.

(2016)

MicroRNA-10 modulates Hox genes expression during Nile tilapia embryonic development,

in Mechanisms of Development

140

pp. 12-18

Full Text UEA Repository

(Article)

(Published)


Wittig, J., Munsterberg, A.

(2016)

The early stages of heart development: insights from chicken embryos,

in Journal of Cardiovascular Development and Disease

3

(2)

article no. 12

Full Text UEA Repository

(Article)

(Published)


Grocott, T., Thomas, P., Munsterberg, A.

(2016)

Atlas Toolkit: Fast registration of 3D morphological datasets in the absence of landmarks,

in Scientific Reports

6

article no. 20732

Full Text UEA Repository

(Article)

(Published)


Lu, W., Shi, Y., Ma, Z., Wang, G., Liu, L., Chuai, M., Song, X., Munsterberg, A., Cao, L., Yang, X.

(2016)

Proper autophagy is indispensable for angiogenesis during chick embryo development,

in Cell Cycle

15

(13)

pp. 1742-1754

Full Text UEA Repository

(Article)

(Published)


Ahmed, A., Ward, N. J., Moxon, S., Lopez-Gomollon, S., Viaut, C., Tomlinson, M. L., Patrushev, I., Gilchrist, M. J., Dalmay, T., Dotlic, D., Munsterberg, A. E., Wheeler, G. N.

(2015)

A database of microRNA expression patterns in Xenopus laevis,

in PLoS ONE

10

(10)

article no. e0138313

Full Text UEA Repository

(Article)

(Published)


Abou-Elhamd, A., Alrefaei, A., Mok, G. F. (., Garcia-Morales, C., Abu-Elmagd, M., Wheeler, G., Munsterberg, A.

(2015)

Klhl31 attenuates β-catenin dependent Wnt signaling and regulates embryo myogenesis,

in Developmental Biology

402

(1)

pp. 61-71

Full Text UEA Repository

(Article)

(Published)


Mok, G. F., Alrefaei, A. F., McColl, J., Grocott, T., Munsterberg, A.

(2015)

Chicken as a Developmental Model,

in eLS.

John Wiley & Sons, Ltd

Full Text UEA Repository

(Chapter)

(Published)


Abu-Elmagd, M., Goljanek-Whysall, K., Wheeler, G., Munsterberg, A.

(2015)

Sprouty2 mediated tuning of signalling is essential for somite myogenesis,

in BMC Medical Genomics

8

(Suppl 1)

article no. S8

Full Text UEA Repository

(Article)

(Published)


Goljanek-Whysall, K., Mok, G. F. (., Alrefaei, A., Kennerley, N., Wheeler, G., Munsterberg, A.

(2014)

myomiR-dependent switching of BAF60 variant incorporation into Brg1 chromatin remodeling complexes during embryo myogenesis,

in Development

141

pp. 3378-3387

Full Text UEA Repository

(Article)

(Published)


Li, Y., Wang, X., Ma, Z., Chuai, M., Munsterberg, A., Lee, K. K., Yang, X.

(2014)

Endoderm contributes to endocardial composition during cardiogenesis,

in Chinese Science Bulletin

59

(22)

pp. 2749-2755

Full Text UEA Repository

(Article)

(Published)


Song, J., Mccoll, J., Camp Navarro, E., Kennerley, N., Mok, G., Mccormick, D., Grocott, T., Wheeler, G., Munsterberg, A.

(2014)

Smad1 transcription factor integrates BMP2 and Wnt3a signals in migrating cardiac progenitor cells,

in Proceedings of the National Academy of Sciences

111

(20)

pp. 7337-7342

Full Text UEA Repository

(Article)

(Published)


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Key Research Interests

My group investigates cellular and molecular mechanisms that underlie embryonic development. We use the chick embryo as a vertebrate model organism and are particularly interested in the signals that control cell fate decisions. For example, developing somites give rise to skeletal muscle, cartilage, bone and tendon. How are these different cell types specified? in the developing heart we have characterized the origin and migration of cells that contribute to different parrts of this important tissue. The mechanistic insights obtained do not only increase our understanding of early embryo development, but also impact areas such as stem cell science and regenerative medicine. 

Video

Current Research Projects 

  • Signalling pathways and cytoskeletal dynamics in somite patterning and myogenesis
  • The origin and migration of cardiac progenitor cells
  • MicroRNA function in skeletal muscle differentiation

 

Life in our research group

The group works in a well-equipped laboratory setting and benefits from shared facilities, in particular the Henry Wellcome Bioimaging lab and Taqman for quantitative PCR. Chick embryos are easy to manipulate using classical and molecular approaches. We are a dynamic group of international students and post-docs and have joint lab-meetings with the Wheeler lab. We participate in the weekly Cell and Developmental Biology seminar series and people from the lab regularly contribute to international conferences in Europe, Asia or North America by giving poster presentations or talks.

PhD Positions

Click here for current PhD opportunities in Biological Sciences. But feel free to email me to discuss projects outside these areas and alternative sources of funding.

Postdocs & Fellows

I am always happy to discuss possibilities for postdoctoral work and collaborations. Possible funding routes include applying for fellowships, e.g. EU Marie Curie fellowships, with me acting as sponsor, or grant applications with you as a named postdoc.

Teaching Interests

  • Skills for Biologists (4008Y)
  • Introduction to Biomedicine (4005Y)
  • Genetics (5009A)
  • Clinical Genetics (5011A)
  • Science communication
  • Molecular and Cellular Principles of Development (6012A)
  • Undergraduate final year Research Projects (6019Y)
  • Frontiers of Molecular Medicine (M201)

External Activities and Indicators of Esteem

  • Scientific Organizer: First BSDB/BSMB joint meeting on "The Musculoskeletal System: from Development to Disease", September 2014, Norwich
  • External examiner: King's College London, NIMR, College of Life Sciences (Dundee), University of Sheffield, ICR, University of Cambridge, St. Georges University London
  • Core member of the BBSRC Committee C: Genes, Development and STEM approaches (2012)
  • Pool/core member of the BBSRC Committee A: Animal systems, health and wellbeing (2009-2011)
  • Member of  BBSRC GDB Committee (2008-9)
  • Member of the Editorial Board of Molecular Biology of the Cell (2005-present)
  • Member of the Editorial Board of Developmental Dynamics (2015-present)
  • Invited speaker: Gordon Conferences on Myogenesis, Il Ciocco (2013)
  • Invited Speaker: EMBO Symposium Cardiac Biology, from Development to Regeneration, Heidelberg (2013)
  • Invited speaker: EMBO Conference on Muscle Development, Differentaition and Disease, Wiesbaden (2011)
  • Visiting Professor, Jinan University, Guangzhou, China (2011)

Awards:

  • Wellcome Trust Research Career Development Fellow (1997-2001)
  • Muscular Dystrophy Association, MDA Postdoctoral Fellow (1994-1996)
  • HFSPO, Postdoctoral Fellow (1992-1994)

Administrative Posts

  • Director of Research (2014 - present)
  • Theme Leader for Cells and Tissues (2010-2013)
  • Organizer CDB Seminars (2010 - present)
  • Member of Studentship selection panel (2006-2010)
  • Liaison Officer for international students (ERASMUS exchange programme with Germany)