Chemistry
Currently available projects
New Methodology in Organic Synthesis
- School:
Chemistry
- Primary Supervisor:
Professor Phil Page
Information
- Start date: October 2013
- Programme: PhD
- Mode of Study: Full Time
- Studentship Length: 3 or 4 years
How to Apply
- Deadline: 28 February 2013. NB Applications are processed as soon as they are received, so early application is encouraged.
- Apply online
Fees & Funding
- Funding Status: Competition Funded Project (EU Students Only)
Further Details - Funding Source: Funding is available from a number of different sources
- Funding Conditions:
Funding is available to EU students. If funding is awarded for this project it will cover tuition fees and stipend for UK students. EU students may be eligible for full funding, or tuition fees only, depending on the funding source.
- Fees: Fees Information (Opens in new window)
Entry Requirements
- Acceptable First Degree:
Chemistry
- Minimum Entry Standard: The standard minimum entry requirement is 2:1
Project Description
Several projects are available within this overall theme.
Total Syntheses: Tagetitoxin; Tetronothiodin; Guaianolides; Lactacystin
These projects involve the total synthesis of biologically active target molecules and provide an excellent training in organic synthesis across a wide range of reaction types.
Asymmetric Catalysis: Epoxidation, Nitrogen Transfer; Click Chemistry; Calixarenes as scaffolds for Polyfunctional Catalysis; Electrochemically Driven Catalytic Processes.
These projects involve the development of new asymmetric methodology and provide an excellent training in enantioselective synthesis and associated analytical techniques.
References
‘Asymmetric Epoxidation Using Binaphthyl- and Biphenyl- Derived Iminium Salt Organocatalysts Featuring Dynamically Controlled Atropoisomerism,' P C B Page, C J Bartlett, Y Chan, D P Day, P Parker, B R Buckley, G A Rassias, A M Z Slawin, S M Allin, J Lacour, A Pinto, J. Org. Chem., 2012, 77, 6128-6138. DOI: 10.1021/jo300915u
‘Harnessing Applied Potential to Oxidation in Water,' B R Buckley, Y Chan, N Dreyfus, C E Elliott, F Marken, P C B Page, Green Chem., 2012, 14, 2221-2225. DOI: 10.1039/c2gc35238a
‘Enantioselective Total Synthesis of (+)-Scuteflorin A using Organocatalytic Asymmetric Epoxidation,' P C B Page, C J Bartlett, Y Chan, D Day, S M Allin, M J McKenzie, J. Org. Chem., 2012, 772-774.
‘Alkoxyresorcin[4]arene Triflates: The Use of Palladium Catalysed Reactions in the Synthesis of Axially Chiral Derivatives with Amino- and/or Alkoxy- Substituents,' P C B Page, T R Bygrave, Y Chan, H Heaney, V McKee, Eur. J. Org. Chem., 2011, 3016-3025.
‘Enantioselective organocatalytic epoxidation driven by electrochemically generated percarbonate and persulfate,' P C B Page, F Marken, C Williamson, Y Chan, B R Buckley, D Bethell, Adv. Synth. Catal., 2008, 350, 1149-1154.
Apply online