Chemistry
Currently available projects
Metallacycle Catalysts for Asymmetric Flow Reactions
- School:
Chemistry
- Primary Supervisor:
Dr Chris Richards
Information
- Start date: October 2013
- Programme: PhD
- Mode of Study: Full Time
- Studentship Length: 3 years
How to Apply
- Deadline: 28 February 2013
- Apply online
Fees & Funding
- Funding Status: Competition Funded Project (EU Students Only)
Further Details - Funding Source: Funding is available from a number of different sources
- Funding Conditions:
Funding is available to EU students. If funding is awarded for this project it will cover tuition fees and stipend for UK students. EU students may be eligible for full funding, or tuition fees only, depending on the funding source.
This project is also open to applicants who have their own funding.
- Fees: Fees Information (Opens in new window)
Entry Requirements
- Acceptable First Degree:
Chemistry
- Minimum Entry Standard: 2:1
Project Description
Continuous flow systems are attractive alternatives to the use of traditional round-bottomed flask based methodologies. Ease of use, reproducibility and scalability make continuous flow especially suited to automated high-throughput synthesis and the continuous production of high-value organic compounds. These advantages may be reinforced by the use of recoverable and recyclable highly active catalysts, especially if directed to the enantioselective synthesis of chiral non-racemic products. This project will utilise chiral metallacycle complexes developed in the Richards group for the discovery of catalyst and precatalyst strategies for the generation by asymmetric flow of key intermediates in the synthesis of bioactive compounds.
References
N. Dendele, F. Bisaro, A.-C. Gaumont, S. Perrio and C. J. Richards, Chem. Commun. 2012, 48, 1991.
J. Amin and C. J. Richards, Chem. Commun. 2012, 48, 10192.
D. Cassar, E. Nagaradja, D. C. D. Butler, D. Villemin and C. J. Richards, Org. Lett. 2012, 14, 894.
H. Nomura and C. J. Richards, Chem. Asian J. 2010, 5, 1726.
M. E. Günay and C. J. Richards, Organometallics 2009, 28, 5833.
Apply online