The group at UEA is internationally recognised for work involving the development of novel thermal, dielectric, rheological and microscopic techniques as analytical tools within the pharmaceutical sciences, with particular emphasis on studying the physical properties of drugs and dosage forms in relation to performance.

Recent interests include the development of modulated temperature DSC, thermally stimulated current spectroscopy and microthermal analysis. Members of the group have won a number of international awards. This group is at the interface between dosage form development and materials science and will be emphatically multidisciplinary in composition.

Dr Francesca Baldelli-Bombelli

  • Development of multifunctional nanoparticles for biomedical applications (controlled drug delivery, hyperthermia effect, etc.)
  • Physical-chemical characterization of nanomaterials in biological fluids (protein corona)
  • Study of nanoparticle-cell interactions from a physical-chemical point of view
  • Biological impact of engineered nanoparticles on living matter

Dr László Fábián

  • Design of multi-component solids, understanding and control of transformations between solid forms of drugs
  • Structural informatics: using structural information to explain and design materials properties
  • Structural and physichochemical characterisation of pharmaceutical materials

Prof Yaroslav Khimyak

  • NMR elucidation of structure and dynamics of materials with limited long-range ordering and soft solids
  • Polymer based and amorphous pharmaceutical systems for drug delivery: understanding of intermolecular interactions
  • Design and application of porous solids for drug delivery

Dr Chris Morris

  • Antimicrobial peptide and nanomaterial disposition in the airways
  • Development of polymer-peptide platforms for delivery of biologically active peptide drugs to the mucosal barriers of the gut and the lung
  • Development of cellular and non-cellular model systems for studying macromolecule interactions with mucosal barriers
Dr Sheng Qi

  • Delivery of poorly water-soluble drugs, including using lipid-based formulations and hot melt extruded solid dispersions
  • Physicochemical characterisation of pharmaceutical materials and dosage forms
  • Amorphous pharmaceuticals

Dr Andrew Round

  • Developing Sliding Rotaxane Force Spectroscopy for single molecule glycan sequence mapping
  • Using AFM to study heterogeneity and complexity in biological macromolecules including pectin and mucin
  • Studying drug-macromolecule interactions at the single molecule level