Office: CAP 2.05 (Office) and CAP 2.10 (Lab) Email: susan.matthews@uea.ac.uk Tel: +44 (0)1603-593986 School Position: Senior Lecturer in Medicinal Chemistry.

PhD Positions
Click here for current PhD opportunities in PHA. But feel free to email me to discuss projects outside these areas and alternative sources of funding.

Susan gained her BPharm from the University of Nottingham in 1991, qualified as a Pharmacist (RPSGB) in 1992 before receiving her PhD in Medicinal Chemistry, from the University of Bath in 1995 for a thesis entitled "Synthesis of Biodegradable Polymers for Delivery of Diagnostic Agents".

She gained Post-Doctoral experience at the Institute of Macromolecular Chemistry, Prague (Royal Society European Fellowship), Johannes Gutenberg Universität, Mainz and the Inorganic Chemistry Laboratory, Oxford before taking up the Kinerton Lectureship of Organic Chemistry at Trinity College, Dublin.

She joined the School in April 2003 as Lecturer of Medicinal Chemistry and was promoted to Senior lecturer in 2008. She is currently the Chair and Academic Programme Secretary, RSC East Anglia Section and Associate Dean for Admissions for the Faculty of Science.

Susan’s research is focused on the interface between chemistry and biology and particularly on the use of supramolecular systems for drug delivery. Current projects include:
 

• Gene delivery through functionalised multicalixarenes
• Cell imaging using fluorescently labelled macrocycles
• Site-specific pro-drug systems for new anti-cancer agents
• New antibiotics related to algae extracts
• New cation and anion receptors based on calixarenes
• Synthesis of new macrocyclic systems

Selected Publications

Taking multicalixarenes into the nanoworld: First third-generation calixarene dendrimer
R. Lalor, A. P. Gunning, V. J. Morris, S. E. Matthews
Chem. Commun., 2010 8665-8667
DOI: 10.1039/C0CC02784G

Achieving High Affinity Towards a Bacterial Lectin Through Multivalent Topological Isomers of Calix[4]arene Glycoconjugates
S. Ceconi, R. Lalor, B. Blanchard, J-P. Praly, A. Imberty, S. E. Matthews, S. Vidal
Chem. Eur. J. 2009, 13232-13240
DOI: 10.1002/chem.200901799

Cellular Uptake of a Fluorescent Calix[4]arene Derivative
R.Lalor, H. Baillie-Johnson, C. Redshaw, S. E. Matthews, A. Mueller
J. Am. Chem. Soc., 2008, 130, 2892-2893
DOI: 10.1021/ja0782596  

A Pyrenyl Appended Triazole-Based Calix[4]arene as a Fluorescent Sensor for Cd²⁺ and Zn^2+.
S-Y. Park, J. Yoon, C. S. Hong, R. Souane, J. S. Kim, S. E. Matthews, J. Vicens
J.Org. Chem., 2008, 73, 8212-8218
DOI:  10.1021/jo8012918