Biography

Professor Bill Fraser was born and educated in Glasgow, graduating from Glasgow University with BSc (Hons) MBChB and MD (Hons). He trained in Glasgow’s teaching hospitals before spending time as a consultant/travelling fellow in Canada.

Career History

Bill Fraser supervises a very active research group investigating the diagnosis and treatment of metabolic bone disease including osteoporosis and Paget’s Disease of bone. He is on the Editorial Board of several journals, a Director of the Supra Regional Assay Service for bone metabolism and calcium homeostasis, and a Medical Advisor to the National Osteoporosis Society. He was a recent recipient of the ACB Foundation Award and presenter of the John Ireland Lecture.

Royal Liverpool University Hospital

  • 1991 appointed Senior Lecturer in Chemical Pathology and Head of the Metabolic Bone Disease Unit 
  • 1998 promoted to Reader
  • 2001 Professor
  • 2008 Head of the Unit of Clinical Chemistry
  • August 2008 appointed Director of the Masters in Research for Clinical Science
  • 2010 Head of Department of Musculoskeletal Biology     

Norwich Medical School, University of East Anglia

  • May 2011 Professor of Medicine 

     


 

 

All Publications

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Wilson, G., Fraser, W., Sharma, A., Eubank, M., Drust, B., Morton, J., Close, G.

(2013)

Markers of bone health, renal function, liver function, anthropometry and perception of mood : A comparison between flat and national hunt jockeys

in International Journal of Sports Medicine

34.

pp. 453-459

Full Text UEA Repository

(Article)


Gregson, C., Tobias, J., Paggiosi, M., McCloskey, E., Crabtree, N., Steel, S. A., Duncan, E., Fan, B., Shepherd, J. A., Fraser, W., Smith, G. D.

(2013)

Analysis of body composition in individuals with high bone mass reveals a marked increase in fat mass in women but not men

in The Journal of Clinical Endocrinology and Metabolism

98.

pp. 818-828

Full Text UEA Repository

(Article)


Mavroeidi, A., Aucott, L., Black, A. J., Reid, D., Macdonald, H., Fraser, W., Absorptiometry, Photon

(2013)

Seasonal Variation in 25(OH)D at Aberdeen (57°N) and Bone Health Indicators- Could Holidays in the Sun and Cod Liver Oil Supplements Alleviate Deficiency?

in PLoS ONE

8.

pp. e53381

Full Text UEA Repository

(Article)


Gilbert, R., Metcalfe, C., Fraser, W., Lewis, S., Donovan, J., Hamdy, F., Neal, D., Lane, J., Martin, R., Tilling, K., Polymorphism, Genetic, Tumor Markers, Biological

(2013)

Associations of circulating 25-hydroxyvitamin D, 1,25-dihydroxyvitamin D, and vitamin D pathway genes with prostate-specific antigen progression in men with localized prostate cancer undergoing active monitoring

in European Journal of Cancer Prevention

22.

pp. 121-125

Full Text UEA Repository

(Article)


Turner, C., Dalton, N., Inaoui, R., Fogelman, I., Hampson, G., Fraser, W.

(2013)

Effect of a 300 000-IU loading dose of ergocalciferol (vitamin D2) on circulating 1,25(OH)-vitamin D and fibroblast growth factor-23 (FGF-23) in vitamin D insufficiency

in The Journal of Clinical Endocrinology and Metabolism

98.

pp. 550-556

Full Text UEA Repository

(Article)


Lawlor, D., Wills, A., Fraser, A., Sayers, A., Fraser, W., Tobias, J., Absorptiometry, Photon

(2013)

Association of maternal vitamin D status during pregnancy with bone-mineral content in off spring : A prospective cohort study

in Lancet

381.

pp. 2176-2183

Full Text UEA Repository

(Article)


Scott, J., Casey, A., Sale, C., Greeves, J., Dutton, J., Fraser, W.

(2013)

Cytokine response to acute running in recreationally-active and endurance-trained men

in European Journal of Applied Physiology

113.

pp. 1871-1882

Full Text UEA Repository

(Article)


Tolppanen, A., Lawlor, D., Sayers, A., Granell, R., Henderson, J., Fraser, W.

(2013)

Prospective association of 25-hydroxyvitamin D3 and D2 with childhood lung function, asthma, wheezing, and flexural dermatitis

in Epidemiology (Cambridge, Mass.)

24.

pp. 310-319

Full Text UEA Repository

(Article)


Close, G., Leckey, J., Patterson, M., Bradley, W., Owens, D., Fraser, W., Morton, J.

(2013)

The effects of vitamin D(3) supplementation on serum total 25[OH]D concentration and physical performance : a randomised dose-response study

in British Journal of Sports Medicine

47.

pp. 692-696

Full Text UEA Repository

(Article)


Loh, N., Gorvin, C., Stechman, M., Ahmad, B., Hannan, F., Piret, S., Thakker, R., Bentley, L., Hough, T., Brown, S., Cox, R., Dimke, H., Verkaart, S., Hoenderop, J., Bindels, R., Tammaro, P., Ashcroft, F., Evans, H., Bellantuono, I., Fraser, W.

(2013)

Autosomal Dominant Hypercalciuria in a Mouse Model Due to a Mutation of the Epithelial Calcium Channel, TRPV5

in PLoS ONE

8.

Full Text UEA Repository

(Article)


Deere, K., Tobias, J., Sayers, A., Viljakainen, H., Lawlor, D., Kemp, J., Sattar, N., Fraser, W.

(2013)

Distinct relationships of intramuscular and subcutaneous fat with cortical bone : Findings from a cross-sectional study of young adult males and females

in The Journal of Clinical Endocrinology and Metabolism

98.

Full Text UEA Repository

(Article)


Glendenning, P., Taranto, M., Chew, G., Inderjeeth, C., Fraser, W.

(2013)

Calculated free and bioavailable vitamin D metabolite concentrations in vitamin D-deficient hip fracture patients after supplementation with cholecalciferol and ergocalciferol

in Bone

56.

pp. 271-275

Full Text UEA Repository

(Article)


Bonilla, C., Gilbert, R., Kemp, J. P., Timpson, N. J., Evans, D. M., Donovan, J. L., Hamdy, F. C., Neal, D. E., Fraser, W. D., Davey, S. G., Lewis, S. J., Lathrop, M., Martin, R. M.

(2013)

Using genetic proxies for lifecourse sun exposure to assess the causal relationship of sun exposure with circulating vitamin d and prostate cancer risk

in Cancer Epidemiology, Biomarkers & Prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology

22.

pp. 597-606

Full Text UEA Repository

(Article)


Luo, Z., Nuyt, A., Delvin, E., Fraser, W. D., Julien, P., Audibert, F., Girard, I., Shatenstein, B., Deal, C., Grenier, E., Garofalo, C., Levy, E.

(2013)

Maternal and fetal leptin, adiponectin levels and associations with fetal insulin sensitivity

in Obesity (Silver Spring, Md.)

21.

pp. 210-216

Full Text UEA Repository

(Article)


Parekh, D., Dancer, R. C., Lax, S., Cooper, M. S., Martineau, A. R., Fraser, W., Tucker, O., Alderson, D., Perkins, G. D., Gao-Smith, F., Thickett, D. R.

(2013)

Vitamin D to prevent acute lung injury following oesophagectomy (VINDALOO) : study protocol for a randomised placebo controlled trial

in Trials

14.

pp. 100

Full Text UEA Repository

(Article)


Albagha, O. M. E., Visconti, M. R., Alonso, N., Wani, S., Goodman, K., Fraser, W. D., Gennari, L., Merlotti, D., Gianfrancesco, F., Esposito, T., Rendina, D., Di Stefano, M., Isaia, G., Brandi, M. L., Guisti, F., Del Pino-montes, J., Corral-gudino, L., Gonzalez-sarmiento, R., Ward, L., Rea, S. L., Ratajczak, T., Walsh, J. P., Ralston, S. H.

(2013)

Common susceptibility alleles and SQSTM1 mutations predict disease extent and severity in a multinational study of patients with Paget's disease

in Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research

28.

pp. 2338-46

Full Text UEA Repository

(Article)


Macdonald, H. M., Wood, A. D., Aucott, L. S., Black, A. J., Fraser, W. D., Mavroeidi, A., Reid, D. M., Secombes, K. R., Simpson, W. G., Thies, F.

(2013)

Hip bone loss is attenuated with 1000 IU but not 400 IU daily vitamin D3: A 1-year double-blind RCT in postmenopausal women : VITAMIN D RCT ON BONE

in Journal of Bone and Mineral Research

28.

pp. 2202-2213

Full Text UEA Repository

(Article)


Lawlor, D. A., Wills, A. K., Fraser, A., Fraser, W. D., Tobias, J. H.

(2013)

Maternal vitamin D status during pregnancy and bone-mineral content in offspring - Authors' reply

in Lancet

382.

pp. 767-768

Full Text UEA Repository

(Article)


Eddington, H., Hudson, J. E., Oliver, R. L., Fraser, W. D., Hutchison, A. J., Kalra, P. A.

(2013)

Variability in parathyroid hormone assays confounds clinical practice in chronic kidney disease patients

in Annals of Clinical Biochemistry

Full Text UEA Repository

(Article)


Kemp, J. P., Sayers, A., Paternoster, L., Evans, D. M., Deere, K., St Pourcain, B., Timpson, N. J., Ring, S. M., Lorentzon, M., Lehtimäki, T., Eriksson, J., Kähönen, M., Raitakari, O., Laaksonen, M., Sievänen, H., Viikari, J., Lyytikäinen, L., Smith, G. D., Fraser, W. D., Vandenput, L., Ohlsson, C., Tobias, J. H.

(2013)

Does bone resorption stimulate periosteal expansion? : A cross sectional analysis of β-C-telopeptides of type I collagen (CTX), genetic markers of the RANKL pathway, and periosteal circumference as measured by pQCT

in Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research

Full Text UEA Repository

(Article)


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