Biography

Professor Bill Fraser was born and educated in Glasgow, graduating from Glasgow University with BSc (Hons) MBChB and MD (Hons). He trained in Glasgow’s teaching hospitals before spending time as a consultant/travelling fellow in Canada.

Career History

Bill Fraser supervises a very active research group investigating the diagnosis and treatment of metabolic bone disease including osteoporosis and Paget’s Disease of bone. He is on the Editorial Board of several journals, a Director of the Supra Regional Assay Service for bone metabolism and calcium homeostasis, and a Medical Advisor to the National Osteoporosis Society. He was a recent recipient of the ACB Foundation Award and presenter of the John Ireland Lecture.

Royal Liverpool University Hospital

  • 1991 appointed Senior Lecturer in Chemical Pathology and Head of the Metabolic Bone Disease Unit 
  • 1998 promoted to Reader
  • 2001 Professor
  • 2008 Head of the Unit of Clinical Chemistry
  • August 2008 appointed Director of the Masters in Research for Clinical Science
  • 2010 Head of Department of Musculoskeletal Biology     

Norwich Medical School, University of East Anglia

  • May 2011 Professor of Medicine 

     


 

 

All Publications

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Sathyapalan, T., Aye, M., Rigby, A., Fraser, W., Thatcher, N., Kilpatrick, E., Atkin, S.

(2017)

Soy reduces bone turnover markers in women during early menopause: A randomized controlled trial,

in Journal of Bone and Mineral Research

32

(1)

pp. 157–164

Full Text UEA Repository

(Article)

(Published)


Sophocleous, A., Robertson, R., Ferreira, N. B., McKenzie, J., Fraser, W. D., Ralston, S. H.

(2017)

Heavy cannabis use is associated with low bone mineral density and an increased risk of fractures,

in American Journal of Medicine

130

(2)

Full Text UEA Repository

(Article)

(Published)


Berry, D. J., Dutton, J., Fraser, W. D., Järvelin, M., Hyppönen, E.

(2017)

Harmonization study between LC-MS/MS and Diasorin RIA for measurement of 25-hydroxyvitamin D concentrations in a large population survey,

in Journal of Clinical Laboratory Analysis

31

(3)

article no. e22049

Full Text UEA Repository

(Article)

(Published)


Owens, D. J., Tang, J. C. Y., Bradley, W. J., Sparks, S. A., Fraser, W. D., Morton, J. P., Close, G. L.

(2017)

Efficacy of High-Dose Vitamin D Supplements for Elite Athletes,

in Medicine and Science in Sports and Exercise

49

(2)

pp. 349–356

Full Text UEA Repository

(Article)

(Published)


Parekh, D., Patel, J. M., Scott, A., Lax, S., Dancer, R. C. A., D’Souza, V., Greenwood, H., Fraser, W. D., Gao, F., Sapey, E., Perkins, G. D., Thickett, D. R.

(2017)

Vitamin D Deficiency in Human and Murine Sepsis,

in Critical Care Medicine

45

(2)

pp. 282–289

Full Text UEA Repository

(Article)

(Published)


Sturgeon, C. M., Sprague, S., Almond, A., Cavalier, E., Fraser, W. D., Algeciras-Schimnich, A., Singh, R., Souberbielle, J., Vesper, H. W.

(2017)

Perspective and priorities for improvement of parathyroid hormone (PTH) measurement – A view from the IFCC Working Group for PTH,

in Clinica Chimica Acta

467

pp. 42-47

Full Text UEA Repository

(Article)

(Published)


Hannam, K., Deere, K. C., Hartley, A., Al-Sari, U. A., Clark, E. M., Fraser, W. D., Tobias, J. H.

(2017)

Habitual levels of higher, but not medium or low, impact physical activity are positively related to lower limb bone strength in older women: Findings from a population-based study using accelerometers to classify impact magnitude,

in Osteoporosis International

Full Text UEA Repository

(Article)

(Published)


Tan, A., Goodman, K., Walker, A., Hudson, J., MacLennan, G. S., Selby, P. L., Fraser, W. D., Ralston, S. H.

(2017)

Long-term randomized trial of intensive versus symptomatic management in Paget's disease of bone: The PRISM-EZ study,

in Journal of Bone and Mineral Research

32

(6)

pp. 1165–1173

Full Text UEA Repository

(Article)

(Published)


Jamil, N. A., Gray, S. R., Fraser, W. D., Fielding, S., Macdonald, H. M.

(2017)

The relationship between vitamin D status and muscle strength in young healthy adults from sunny climate countries currently living in the northeast of Scotland,

in Osteoporosis International

28

(4)

pp. 1433–1443

Full Text UEA Repository

(Article)

(Published)


Gregson, C., Hardcastle, S., Murphy, A., Faber, B., Fraser, W., Williams, M., Davey Smith, G., Tobias, J.

(2017)

High Bone Mass is associated with bone-forming features of osteoarthritis in non-weight bearing joints independent of body mass index,

in Bone

97

pp. 306–313

Full Text UEA Repository

(Article)

(Published)


Townsend, R., Elliott-Sale, K. J., Currell, K., Tang, J., Fraser, W. D., Sale, C.

(2017)

The Effect of Postexercise Carbohydrate and Protein Ingestion on Bone Metabolism,

in Medicine & Science in Sports & Exercise

49

(6)

pp. 1209-1218

Full Text UEA Repository

(Article)

(Published)


Saleh, L., Tang, J. C., Gawinecka, J., Boesch, L., Fraser, W. D., von Eckardstein, A., Nowak, A.

(2017)

Impact of a single oral dose of 100,000 IU vitamin D3 on profiles of serum 25(OH)D3 and its metabolites 24,25(OH)2D3, 3-epi-25(OH)D3, and 1,25(OH)2D3 in adults with vitamin D insufficiency,

in Clinical Chemistry and Laboratory Medicine

Full Text UEA Repository

(Article)

(E-pub ahead of print)


Varley, I., Hughes, D. C., Greeves, J. P., Fraser, W., Sale, C.

(2017)

Increased training volume improves bone density and cortical area in adolescent football players,

in International Journal of Sports Medicine

38

(5)

pp. 341-346

Full Text UEA Repository

(Article)

(Published)


Cleal, J. K., Hargreaves, M. R., Poore, K. R., Tang, J. C. Y., Fraser, W. D., Hanson, M. A., Green, L. R.

(2017)

Reduced fetal vitamin D status by maternal undernutrition during discrete gestational windows in sheep,

in Journal of Developmental Origins of Health and Disease

8

(3)

pp. 370-381

Full Text UEA Repository

(Article)

(Published)


Green, D., Mohorianu, I., McNamara, I., Dalmay, T., Fraser, W. D.

(2017)

miR-16 is highly expressed in Paget’s associated osteosarcoma,

in Endocrine-Related Cancer (ERC)

24

(5)

pp. L27-L31

Full Text

(Letter)

(Published)


Jones, R. L., Barnett, C. T., Davidson, J., Maritza, B., Fraser, W. D., Harris, R., Sale, C.

(2017)

β-alanine supplementation improves in-vivo fresh and fatigued skeletal muscle relaxation speed,

in European Journal of Applied Physiology

117

(5)

pp. 867–879

Full Text UEA Repository

(Article)

(Published)


Tang, J. C. Y., Nicholls, H., Piec, I., Washbourne, C. J., Dutton, J. J., Jackson, S., Greeves, J., Fraser, W. D.

(2017)

Reference intervals for serum 24,25-Dihydroxyvitamin D and the ratio with 25-Hydroxyvitamin established using a newly developed LC-MS/MS method,

in Journal of Nutritional Biochemistry

46

pp. 21–29

Full Text UEA Repository

(Article)

(E-pub ahead of print)


Hauser, B., Zhao, S., Visconti, M. R., Riches, P. L., Fraser, W. D., Piec, I., Goodson, N. J., Ralston, S. H.

(2017)

Autoantibodies to Osteoprotegerin are Associated with Low Hip Bone Mineral Density and History of Fractures in Axial Spondyloarthritis: A Cross-Sectional Observational Study,

in Calcified Tissue International

Full Text UEA Repository

(Article)

(E-pub ahead of print)


Lynch Cronin, I., Byrne, F., Doyle, R., Chipchase, A., Fraser, W., Eustace, J.

(2017)

The effect of short-term vitamin D supplementation on hypercalcaemic vitamin D insufficient renal transplant recipients,

in Nephrology Dialysis Transplantation

32

(suppl_3)

article no. SP377

pp. iii239

Full Text

(Abstract)

(Published)


He, C., Fraser, W., Tang, J., Brown, K., Renwick, S., Rudland-Thomas, J., Teah, J., Tanqueray, E., Gleeson, M.

(2016)

The effect of 14 weeks of vitamin D3 supplementation on antimicrobial peptides and proteins in athletes,

in Journal of Sports Sciences

34

(1)

pp. 67-74

Full Text UEA Repository

(Article)

(Published)


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