Biography

Professor Bill Fraser was born and educated in Glasgow, graduating from Glasgow University with BSc (Hons) MBChB and MD (Hons). He trained in Glasgow’s teaching hospitals before spending time as a consultant/travelling fellow in Canada.

Career History

Bill Fraser supervises a very active research group investigating the diagnosis and treatment of metabolic bone disease including osteoporosis and Paget’s Disease of bone. He is on the Editorial Board of several journals, a Director of the Supra Regional Assay Service for bone metabolism and calcium homeostasis, and a Medical Advisor to the National Osteoporosis Society. He was a recent recipient of the ACB Foundation Award and presenter of the John Ireland Lecture.

Royal Liverpool University Hospital

  • 1991 appointed Senior Lecturer in Chemical Pathology and Head of the Metabolic Bone Disease Unit 
  • 1998 promoted to Reader
  • 2001 Professor
  • 2008 Head of the Unit of Clinical Chemistry
  • August 2008 appointed Director of the Masters in Research for Clinical Science
  • 2010 Head of Department of Musculoskeletal Biology     

Norwich Medical School, University of East Anglia

  • May 2011 Professor of Medicine 

     


 

 

All Publications

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Varley, I., Hughes, D. C., Greeves, J. P., Fraser, W. D., Sale, C.

(2018)

SNPs in the vicinity of P2X7R, RANK/RANKL/OPG and Wnt signalling pathways and their association with bone phenotypes in academy footballers,

in Bone

108

pp. 179–185

Full Text UEA Repository

(Article)

(Published)


Hammond, M., Clark, A. B., Cahn, A. P., Chilvers, E. R., Fraser, W. D., Livermore, D. M., Maher, T. M., Parfrey, H., Swart, A. M., Stirling, S., Thickett, D., Whyte, M., Wilson, A.

(2018)

The Efficacy and Mechanism Evaluation of Treating Idiopathic Pulmonary fibrosis with the Addition of Co-trimoxazole (EME-TIPAC): study protocol for a randomised controlled trial,

in Trials

19

article no. 89

Full Text UEA Repository

(Article)

(Published)


Goljanek-Whysall, K., Tridimas, A., McCormick, R., Russell, N., Sloman, M., Sorani, A., Fraser, W. D., Hannan, F. M.

(2018)

Identification of a novel loss-of-function PHEX mutation, Ala720Ser, in a sporadic case of adult-onset hypophosphatemic osteomalacia,

in Bone

106

pp. 30-34

Full Text UEA Repository

(Article)

(Published)


Macdonald, H., Gryka, A., Tang, J., Aucott, L., Fraser, W., Wood, A.

(2017)

Longevity of daily oral Vitamin D3 supplementation: Differences in 25OHD and 24,25(OH)2D observed 2 years after cessation of a 1-year randomized controlled trial (VICtORy RECALL),

in Osteoporosis International

28

(12)

pp. 3361–3372

Full Text UEA Repository

(Article)

(Published)


Papageorgiou, M., Elliott-Sale, K. J., Parsons, A., Tang, J., Greeves, J. P., Fraser, W. D., Sale, C.

(2017)

Effects of reduced energy availability on bone metabolism in women and men,

in Bone

105

pp. 191-199

Full Text UEA Repository

(Article)

(Published)


Green, D., Mohorianu, I., Piec, I., Turner, J., Beadsmoore, C., Toms, A., Ball, R., Nolan, J., McNamara, I., Dalmay, T., Fraser, W. D.

(2017)

MicroRNA expression in a phosphaturic mesenchymal tumour,

in Bone Reports

7

pp. 63–69

Full Text UEA Repository

(Article)

(Published)


Sathyapalan, T., Aye, M., Rigby, A. S., Fraser, W. D., Kilpatrick, E. S., Atkin, S. L.

(2017)

Effect of soy on bone turn-over markers in men with type 2 diabetes and hypogonadism – a randomised controlled study,

in Scientific Reports

7

article no. 15366

Full Text UEA Repository

(Article)

(Published)


Varley, I., Hughes, D. C., Greeves, J. P., Stellingwerff, T., Ranson, C., Fraser, W. D., Sale, C.

(2017)

The association of novel polymorphisms with stress fracture injury in Elite Athletes: Further insights from the SFEA cohort,

in Journal of Science and Medicine in Sport

Full Text UEA Repository

(Article)

(E-pub ahead of print)


Al Riyami, S., Tang, J. C. Y., Galitzer, H., Fraser, W.

(2017)

LC-MS/MS measurement of parathyroid hormone PTH (1-34): Use in studying oral PTH (1-34) administration and possible diagnostic application in pseudohypoparathyroidism.,

Full Text

(Poster)

(Published)


Earl, K. E., Sakellariou, G. K., Sinclair, M., Fenech, M., Croden, F., Owens, D. J., Tang, J., Miller, A., Lawton, C., Dye, L., Close, G. L., Fraser, W. D., McArdle, A., Beadsworth, M. B. J.

(2017)

Vitamin D status in chronic fatigue syndrome/myalgic encephalomyelitis: a cohort study from the North-West of England,

in BMJ Open

7

article no. e015296

Full Text UEA Repository

(Article)

(Published)


Saleh, L., Tang, J. C., Gawinecka, J., Boesch, L., Fraser, W. D., von Eckardstein, A., Nowak, A.

(2017)

Impact of a single oral dose of 100,000 IU vitamin D3 on profiles of serum 25(OH)D3 and its metabolites 24,25(OH)2D3, 3-epi-25(OH)D3, and 1,25(OH)2D3 in adults with vitamin D insufficiency,

in Clinical Chemistry and Laboratory Medicine

55

(12)

pp. 1912-1921

Full Text UEA Repository

(Article)

(Published)


Hannam, K., Deere, K. C., Hartley, A., Al-Sari, U. A., Clark, E. M., Fraser, W. D., Tobias, J. H.

(2017)

Habitual levels of higher, but not medium or low, impact physical activity are positively related to lower limb bone strength in older women: Findings from a population-based study using accelerometers to classify impact magnitude,

in Osteoporosis International

28

(10)

pp. 2813–2822

Full Text UEA Repository

(Article)

(Published)


Hauser, B., Zhao, S., Visconti, M. R., Riches, P. L., Fraser, W. D., Piec, I., Goodson, N. J., Ralston, S. H.

(2017)

Autoantibodies to Osteoprotegerin are Associated with Low Hip Bone Mineral Density and History of Fractures in Axial Spondyloarthritis: A Cross-Sectional Observational Study,

in Calcified Tissue International

101

(4)

pp. 375–383

Full Text UEA Repository

(Article)

(Published)


Hanusch, B., Tuck, S., McNally, R., Wu, J., Prediger, M., Walker, J., Tang, J., Piec, I., Fraser, W., Datta, H., Francis, R.

(2017)

Does regional loss of bone density explain low trauma distal forearm fractures in men (the Mr F study)?,

in Osteoporosis International

28

(10)

pp. 2877–2886

Full Text UEA Repository

(Article)

(Published)


Burstein, G., Tang, J. C. Y., Rothner, A., Galitzer, H., Schwartz, P., Fraser, W.

(2017)

Enhanced bioavailability and reduced pharmacokinetic variability of Oral PTH (1-34) in man,

Full Text

(Poster)

(Published)


Al Riyami, S., Tang, J. C. Y., Dutton, J., Washbourne, C., Galitzer, H., Fraser, W.

(2017)

Development and Validation of a LC-MS/MS Assay for Quantification of Parathyroid Hormone (PTH 1-34) in human Plasma,

Full Text

(Poster)

(Published)


Al Riyami, S., Tang, J. C. Y., Galitzer, H., Fraser, W.

(2017)

Measurements of Osteoanabolic agents PTH (1-34) and PTHrP (1-36) in therapeutic studies and clinical diagnostics,

Full Text

(Poster)

(Published)


Piec, I., Dutton, J., Al Riyami, S., Washbourne, C., Schoenmakers, I., Galitzer, H., Burshtein, G., Schwartz, P., Tang, J. C. Y., Fraser, W.

(2017)

A LC-MS/MS method for the diagnostic measurement of cAMP in plasma and urine,

(Poster)

(Published)


Tang, J. C. Y., Nicholls, H., Ball, N., Dutton, J., Piec, I., Rudge, J., Washbourne, C., Fraser, W.

(2017)

Assessment of vitamin D status using MitraTM volumetric absorptive microsampling (VAMS) device,

Full Text

(Poster)

(Published)


Kishnani, P. S., Rush, E. T., Arundel, P., Bishop, N., Dahir, K., Fraser, W., Harmatz, P., Linglart, A., Munns, C. F., Nunes, M. E., Saal, H. M., Seefried, L., Ozono, K.

(2017)

Monitoring guidance for patients with hypophosphatasia treated with asfotase alfa,

in Molecular Genetics and Metabolism

122

(1-2)

pp. 4–17

Full Text UEA Repository

(Article)

(Published)


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