Biography

Professor Bill Fraser was born and educated in Glasgow, graduating from Glasgow University with BSc (Hons) MBChB and MD (Hons). He trained in Glasgow’s teaching hospitals before spending time as a consultant/travelling fellow in Canada.

Career History

Bill Fraser supervises a very active research group investigating the diagnosis and treatment of metabolic bone disease including osteoporosis and Paget’s Disease of bone. He is on the Editorial Board of several journals, a Director of the Supra Regional Assay Service for bone metabolism and calcium homeostasis, and a Medical Advisor to the National Osteoporosis Society. He was a recent recipient of the ACB Foundation Award and presenter of the John Ireland Lecture.

Royal Liverpool University Hospital

  • 1991 appointed Senior Lecturer in Chemical Pathology and Head of the Metabolic Bone Disease Unit 
  • 1998 promoted to Reader
  • 2001 Professor
  • 2008 Head of the Unit of Clinical Chemistry
  • August 2008 appointed Director of the Masters in Research for Clinical Science
  • 2010 Head of Department of Musculoskeletal Biology     

Norwich Medical School, University of East Anglia

  • May 2011 Professor of Medicine 

     


 

 

All Publications

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He, C., Fraser, W., Tang, J., Brown, K., Renwick, S., Rudland-Thomas, J., Teah, J., Tanqueray, E., Gleeson, M.

(2016)

The effect of 14 weeks of vitamin D3 supplementation on antimicrobial peptides and proteins in athletes

in Journal of Sports Sciences

34.

pp. 67-74

Full Text UEA Repository

(Article)


Fraser, W., Varley, I., Greeves, J., Sale, C., Friedman, E., Moran, D., Yanovich, R., Wilson, P. J., Gartland, A., Hughes, D. C., Stellingwerff, T., Ranson, C., Gallagher, J. A.

(2016)

Functional Polymorphisms in the P2X7 Receptor Gene are Associated with Stress Fracture Injury

in Purinergic Signalling

12.

pp. 103-113

Full Text UEA Repository

(Article)


Piec, I., Washbourne, C., Tang, J., Fisher, E., Greeves, J., Jackson, S., Fraser, W. D.

(2016)

How Accurate is Your Sclerostin Measurement?: Comparison Between Three Commercially Available Sclerostin ELISA Kits

in Calcified Tissue International

Full Text UEA Repository

(Article)


Impey, S. G., Smith, D., Robinson, A., Owens, D., Bartlett, J., Smith, K., Limb, M., Tang, J., Fraser, W., Close, G., Morton, J. P.

(2015)

Leucine-enriched protein feeding does not impair exercise-induced free fatty acid availability and lipid oxidation: beneficial implications for training in carbohydrate-restricted states

Full Text UEA Repository

(Paper)


Francis, R. M., Aspray, T. J., Bowring, C. E., Fraser, W. D., Gittoes, N. J., Javaid, M. K., Macdonald, H. M., Patel, S., Selby, P. L., Tanna, N.

(2015)

National Osteoporosis Society practical clinical guideline on vitamin D and bone health

in Maturitas

80.

pp. 119-121

Full Text UEA Repository

(Article)


Varley, I., Hughes, D. C., Greeves, J. P., Stellingwerff, T., Ranson, C., Fraser, W. D., Sale, C.

(2015)

RANK/RANKL/OPG pathway: genetic associations with stress fracture period prevalence in elite athletes

in Bone

71.

pp. 131-136

Full Text UEA Repository

(Article)


Owens, D. J., Fraser, W. D., Close, G. L., 1, 25-dihydroxyvitamin-D

(2015)

Vitamin D and the athlete: emerging insights

in European Journal of Sport Science

15.

pp. 73-84

Full Text UEA Repository

(Article)


Gilbert, R., Bonilla, C., Metcalfe, C., Lewis, S., Evans, D. M., Fraser, W. D., Kemp, J. P., Donovan, J. L., Hamdy, F. C., Neal, D. E., Lane, J. A., Smith, G. D., Lathrop, M., Martin, R. M., 1, 25-dihydroxyvitamin-D

(2015)

Associations of vitamin D pathway genes with circulating 25-hydroxyvitamin-D, 1,25-dihydroxyvitamin-D, and prostate cancer: a nested case-control study

in Cancer Causes & Control

26.

pp. 205-18

Full Text UEA Repository

(Article)


Impey, S. G., Smith, D., Robinson, A. L., Owens, D. J., Bartlett, J. D., Smith, K., Limb, M., Tang, J., Fraser, W. D., Close, G. L., Morton, J. P.

(2015)

Leucine-enriched protein feeding does not impair exercise-induced free fatty acid availability and lipid oxidation: beneficial implications for training in carbohydrate-restricted states

in Amino Acids

47.

pp. 407-16

Full Text UEA Repository

(Article)


Green, D., Dalmay, T., Fraser, W.

(2015)

Paget's disease of bone-associated osteosarcoma: molecular basis, signs and symptoms, treatment and research

UEA Repository

(Article)


Real, A., Gilbert, N., Hauser, B., Kennedy, N., Shand, A., Gillett, H., Gillett, P., Goddard, C., Cebolla, Á., Sousa, C., Fraser, W., Satsangi, J., Ralston, S., Riches, P.

(2015)

Characterisation of osteoprotegerin autoantibodies in coeliac disease

in Calcified Tissue International

97.

pp. 125-133

Full Text UEA Repository

(Article)


Hannan, F. M., Walls, G. V., Babinsky, V. N., Nesbit, M. A., Kallay, E., Hough, T. A., Fraser, W. D., Cox, R. D., Hu, J., Spiegel, A. M., Thakker, R. V.

(2015)

The calcilytic agent NPS 2143 rectifies hypocalcemia in a mouse model with an activating calcium-sensing-receptor (CaSR) mutation: relevance to autosomal dominant hypocalcemia type 1 (ADH1)

in Endocrinology

156.

pp. en20151269

Full Text UEA Repository

(Article)


Dancer, R. C. A., Parekh, D., Lax, S., D'Souza, V., Zheng, S., Bassford, C. R., Park, D., Bartis, D. G., Mahida, R., Turner, A. M., Sapey, E., Wei, W., Naidu, B., Stewart, P. M., Fraser, W. D., Christopher, K. B., Cooper, M. S., Gao, F., Sansom, D. M., Martineau, A. R., Perkins, G. D., Thickett, D. R.

(2015)

Vitamin D deficiency contributes directly to the acute respiratory distress syndrome (ARDS)

in Thorax

70.

pp. 617-24

Full Text UEA Repository

(Article)


Green, D., Dalmay, T., Fraser, W.

(2015)

Role of miR-140 in embryonic bone development and cancer

in Clinical Science

129.

pp. 863-873

Full Text UEA Repository

(Article)


Gregson, C. L., Wheeler, L., Hardcastle, S. A., Appleton, L. H., Addison, K. A., Brugmans, M., Clark, G. R., Ward, K. A., Paggiosi, M., Stone, M., Thomas, J., Agarwal, R., Poole, K., McCloskey, E., Fraser, W. D., Williams, E., Bullock, A. N., Smith, G. D., Brown, M. A., Tobias, J. H., Duncan, E. L.

(2015)

Mutations in Known Monogenic High Bone Mass Loci Only Explain a Small Proportion of High Bone Mass cases

in Journal of Bone and Mineral Research

Full Text UEA Repository

(Article)


Piec, I., Paddock, S., Washbourne, C., Tang, J., Greeves, J., Jackson, S., Ralston, S., Riches, P., McDonald, H., Fraser, W.

(2015)

Non-osteoporotic post-menopausal women do not have elevated concentrations of autoantibodies against osteoprotegerin

(Poster)


Piec, I., Nicholls, H., Tang, J., Washbourne, C., Fraser, W.

(2015)

FGF23 metabolism, a new paradigm for chronic kidney disease

(Poster)


Eddington, H., Hudson, J. E., Oliver, R. L., Fraser, W. D., Hutchison, A. J., Kalra, P. A.

(2014)

Variability in parathyroid hormone assays confounds clinical practice in chronic kidney disease patients

in Annals of Clinical Biochemistry

51.

pp. 228-236

Full Text UEA Repository

(Article)


Kemp, J. P., Sayers, A., Paternoster, L., Evans, D. M., Deere, K., St Pourcain, B., Timpson, N. J., Ring, S. M., Lorentzon, M., Lehtimäki, T., Eriksson, J., Kähönen, M., Raitakari, O., Laaksonen, M., Sievänen, H., Viikari, J., Lyytikäinen, L., Smith, G. D., Fraser, W. D., Vandenput, L., Ohlsson, C., Tobias, J. H.

(2014)

Does bone resorption stimulate periosteal expansion?: A cross sectional analysis of β-C-telopeptides of type I collagen (CTX), genetic markers of the RANKL pathway, and periosteal circumference as measured by pQCT

in Journal of Bone and Mineral Research

29.

pp. 1015–1024

Full Text UEA Repository

(Article)


Williams, D. M., Fraser, A., Sayers, A., Fraser, W. D., Hyppönen, E., Smith, G. D., Sattar, N., Lawlor, D. A.

(2014)

Associations of childhood 25-hydroxyvitamin D2 and D3 and cardiovascular risk factors in adolescence: prospective findings from the Avon Longitudinal Study of Parents and Children

in European Journal of Preventive Cardiology

21.

pp. 281-90

Full Text UEA Repository

(Article)


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