Biography

Professor Bill Fraser was born and educated in Glasgow, graduating from Glasgow University with BSc (Hons) MBChB and MD (Hons). He trained in Glasgow’s teaching hospitals before spending time as a consultant/travelling fellow in Canada.

Career History

Bill Fraser supervises a very active research group investigating the diagnosis and treatment of metabolic bone disease including osteoporosis and Paget’s Disease of bone. He is on the Editorial Board of several journals, a Director of the Supra Regional Assay Service for bone metabolism and calcium homeostasis, and a Medical Advisor to the National Osteoporosis Society. He was a recent recipient of the ACB Foundation Award and presenter of the John Ireland Lecture.

Royal Liverpool University Hospital

  • 1991 appointed Senior Lecturer in Chemical Pathology and Head of the Metabolic Bone Disease Unit 
  • 1998 promoted to Reader
  • 2001 Professor
  • 2008 Head of the Unit of Clinical Chemistry
  • August 2008 appointed Director of the Masters in Research for Clinical Science
  • 2010 Head of Department of Musculoskeletal Biology     

Norwich Medical School, University of East Anglia

  • May 2011 Professor of Medicine 

     


 

 

All Publications

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Goljanek-Whysall, K., Tridimas, A., McCormick, R., Russell, N., Sloman, M., Sorani, A., Fraser, W. D., Hannan, F. M.

(2018)

Identification of a novel loss-of-function PHEX mutation, Ala720Ser, in a sporadic case of adult-onset hypophosphatemic osteomalacia,

in Bone

106

pp. 30-34

Full Text UEA Repository

(Article)

(E-pub ahead of print)


Hannam, K., Deere, K. C., Hartley, A., Al-Sari, U. A., Clark, E. M., Fraser, W. D., Tobias, J. H.

(2017)

Habitual levels of higher, but not medium or low, impact physical activity are positively related to lower limb bone strength in older women: Findings from a population-based study using accelerometers to classify impact magnitude,

in Osteoporosis International

28

(10)

pp. 2813–2822

Full Text UEA Repository

(Article)

(Published)


Hauser, B., Zhao, S., Visconti, M. R., Riches, P. L., Fraser, W. D., Piec, I., Goodson, N. J., Ralston, S. H.

(2017)

Autoantibodies to Osteoprotegerin are Associated with Low Hip Bone Mineral Density and History of Fractures in Axial Spondyloarthritis: A Cross-Sectional Observational Study,

in Calcified Tissue International

101

(4)

pp. 375–383

Full Text UEA Repository

(Article)

(Published)


Hanusch, B., Tuck, S., McNally, R., Wu, J., Prediger, M., Walker, J., Tang, J., Piec, I., Fraser, W., Datta, H., Francis, R.

(2017)

Does regional loss of bone density explain low trauma distal forearm fractures in men (the Mr F study)?,

in Osteoporosis International

28

(10)

pp. 2877–2886

Full Text UEA Repository

(Article)

(Published)


Macdonald, H., Gryka, A., Tang, J., Aucott, L., Fraser, W., Wood, A.

(2017)

Longevity of daily oral Vitamin D3 supplementation: Differences in 25OHD and 24,25(OH)2D observed 2 years after cessation of a 1-year randomized controlled trial (VICtORy RECALL),

in Osteoporosis International

Full Text UEA Repository

(Article)

(E-pub ahead of print)


Green, D., Mohorianu, I., Piec, I., Turner, J., Beadsmoore, C., Toms, A., Ball, R., Nolan, J., McNamara, I., Dalmay, T., Fraser, W. D.

(2017)

MicroRNA expression in a phosphaturic mesenchymal tumour,

in Bone Reports

7

pp. 63–69

Full Text UEA Repository

(Article)

(E-pub ahead of print)


Kishnani, P. S., Rush, E. T., Arundel, P., Bishop, N., Dahir, K., Fraser, W., Harmatz, P., Linglart, A., Munns, C. F., Nunes, M. E., Saal, H. M., Seefried, L., Ozono, K.

(2017)

Monitoring guidance for patients with hypophosphatasia treated with asfotase alfa,

in Molecular Genetics and Metabolism

122

(1-2)

pp. 4–17

Full Text UEA Repository

(Article)

(Published)


Papageorgiou, M., Elliott-Sale, K. J., Parsons, A., Tang, J., Greeves, J. P., Fraser, W. D., Sale, C.

(2017)

Effects of reduced energy availability on bone metabolism in women and men,

in Bone

Full Text UEA Repository

(Article)

(E-pub ahead of print)


Tang, J. C. Y., Nicholls, H., Piec, I., Washbourne, C. J., Dutton, J. J., Jackson, S., Greeves, J., Fraser, W. D.

(2017)

Reference intervals for serum 24,25-Dihydroxyvitamin D and the ratio with 25-Hydroxyvitamin established using a newly developed LC-MS/MS method,

in Journal of Nutritional Biochemistry

46

pp. 21–29

Full Text UEA Repository

(Article)

(Published)


Tan, A., Goodman, K., Walker, A., Hudson, J., MacLennan, G. S., Selby, P. L., Fraser, W. D., Ralston, S. H.

(2017)

Long-term randomized trial of intensive versus symptomatic management in Paget's disease of bone: The PRISM-EZ study,

in Journal of Bone and Mineral Research

32

(6)

pp. 1165–1173

Full Text UEA Repository

(Article)

(Published)


Townsend, R., Elliott-Sale, K. J., Currell, K., Tang, J., Fraser, W. D., Sale, C.

(2017)

The Effect of Postexercise Carbohydrate and Protein Ingestion on Bone Metabolism,

in Medicine & Science in Sports & Exercise

49

(6)

pp. 1209-1218

Full Text UEA Repository

(Article)

(Published)


Cleal, J. K., Hargreaves, M. R., Poore, K. R., Tang, J. C. Y., Fraser, W. D., Hanson, M. A., Green, L. R.

(2017)

Reduced fetal vitamin D status by maternal undernutrition during discrete gestational windows in sheep,

in Journal of Developmental Origins of Health and Disease

8

(3)

pp. 370-381

Full Text UEA Repository

(Article)

(Published)


Lynch Cronin, I., Byrne, F., Doyle, R., Chipchase, A., Fraser, W., Eustace, J.

(2017)

The effect of short-term vitamin D supplementation on hypercalcaemic vitamin D insufficient renal transplant recipients,

in Nephrology Dialysis Transplantation

32

(suppl_3)

article no. SP377

pp. iii239

Full Text

(Abstract)

(Published)


Green, D., Mohorianu, I., McNamara, I., Dalmay, T., Fraser, W. D.

(2017)

miR-16 is highly expressed in Paget’s associated osteosarcoma,

in Endocrine-Related Cancer (ERC)

24

(5)

pp. L27-L31

Full Text

(Letter)

(Published)


Berry, D. J., Dutton, J., Fraser, W. D., Järvelin, M., Hyppönen, E.

(2017)

Harmonization study between LC-MS/MS and Diasorin RIA for measurement of 25-hydroxyvitamin D concentrations in a large population survey,

in Journal of Clinical Laboratory Analysis

31

(3)

article no. e22049

Full Text UEA Repository

(Article)

(Published)


Varley, I., Hughes, D. C., Greeves, J. P., Fraser, W., Sale, C.

(2017)

Increased training volume improves bone density and cortical area in adolescent football players,

in International Journal of Sports Medicine

38

(5)

pp. 341-346

Full Text UEA Repository

(Article)

(Published)


Jones, R. L., Barnett, C. T., Davidson, J., Maritza, B., Fraser, W. D., Harris, R., Sale, C.

(2017)

β-alanine supplementation improves in-vivo fresh and fatigued skeletal muscle relaxation speed,

in European Journal of Applied Physiology

117

(5)

pp. 867–879

Full Text UEA Repository

(Article)

(Published)


Sturgeon, C. M., Sprague, S., Almond, A., Cavalier, E., Fraser, W. D., Algeciras-Schimnich, A., Singh, R., Souberbielle, J., Vesper, H. W.

(2017)

Perspective and priorities for improvement of parathyroid hormone (PTH) measurement – A view from the IFCC Working Group for PTH,

in Clinica Chimica Acta

467

pp. 42-47

Full Text UEA Repository

(Article)

(Published)


Jamil, N. A., Gray, S. R., Fraser, W. D., Fielding, S., Macdonald, H. M.

(2017)

The relationship between vitamin D status and muscle strength in young healthy adults from sunny climate countries currently living in the northeast of Scotland,

in Osteoporosis International

28

(4)

pp. 1433–1443

Full Text UEA Repository

(Article)

(Published)


Gregson, C., Hardcastle, S., Murphy, A., Faber, B., Fraser, W., Williams, M., Davey Smith, G., Tobias, J.

(2017)

High Bone Mass is associated with bone-forming features of osteoarthritis in non-weight bearing joints independent of body mass index,

in Bone

97

pp. 306–313

Full Text UEA Repository

(Article)

(Published)


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