Biography

Dr Lindsay Hall is the Microbiome Research Leader at the Quadram Institute (www.quadram.ac.uk). Lindsay is also an Honorary Senior Lecturer at the Norwich Medical School at UEA.

Dr Hall qualified with a BSc (Hons) in Microbiology from the University of Glasgow in 2003. She went on to study for a PhD in Microbiology and Immunology at the Wellcome Trust Sanger Institute under the supervision of Prof Gordon Dougan (FRS).  In 2007 Lindsay took up a postdoctoral position at the APC Microbiome Institute, University College Cork in Ireland, after which she returned to the UK in 2011 to take up a lecturing and Principle Investigator position within the Norwich Medical School, UEA. In 2013 Lindsay was awarded a 5 year Wellcome Trust New Investigator Award and in 2014 was promoted to senior lecturer in Gastrointestinal Sciences. In November 2015 she moved to the Quadram Institute and she also currently holds an honorary position at UEA. See www.halllab.co.uk for more details. 

Career History

2015-current Microbiome Research Leader, Quadram Institute, Norwich Research Park, Norwich.

2015-current Honorary Senior Lecturer, Norwich Medical School, Unoversity of East Anglia, Norwich Research Park, Norwich 

2014-2015 Senior Lecturer and Research Leader in Gastrointestinal Sciences, Norwich Medical School, University of East Anglia, Norwich Research Park, Norwich.

2011-current Research Leader, Institute of Food Research, Norwich Research Park, Norwich.

2011-2014 Lecturer and Research Leader in Gastrointestinal Sciences, Norwich Medical School, University East Anglia, Norwich Research Park, Norwich.

2007 – 2011 Post Doctoral Research Fellow, Alimentary Pharmabiotic Centre, Biosciences Institute, University College Cork, Cork, Ireland.

2003 – 2007: Ph.D, University of Cambridge. The Wellcome Trust Sanger Institute, Hinxton, Cambridge.

1999 – 2003: BSc (Hons), Microbiology, University of Glasgow.

All Publications

<- Page 1 of 2 ->

Alcon-Giner, C., Caim, S., Mitra, S., Ketskemety, J., Wegmann, U., Wain, J., Belteki, G., Clarke, P., Hall, L. J.

(2017)

Optimisation of 16S rRNA gut microbiota profiling of extremely low birth weight infants,

in BMC Genomics

18

article no. 841

Full Text UEA Repository

(Article)

(Published)


Kiu, R., Caim, S., Alcon-Giner, C., Belteki, G., Clarke, P., Pickard, D., Dougan, G., Hall, L. J.

(2017)

Preterm infant-associated Clostridium tertium, Clostridium cadaveris and Clostridium paraputrificum strains: genomic and evolutionary insights,

in Genome Biology and Evolution

9

(10)

pp. 2707–2714

Full Text UEA Repository

(Article)

(Published)


Forde, P. F., Hall, L., de Kruijf, M., Bourke, M. G., Doddy, T., Sadadcharam, M., Soden, D. M.

(2015)

Non-viral immune electro-gene therapy induces potent anti-tumour responses and has a curative effect in murine colon adenocarcinoma and melanoma cancer models,

in Gene Therapy

22

pp. 29–39

Full Text UEA Repository

(Article)

(Published)


Hall, L. J., Walshaw, J., Watson, A. J. M.

(2014)

Gut Microbiome in New-Onset Crohn's Disease,

in Gastroenterology

147

(4)

pp. 932–934

Full Text UEA Repository

(Article)

(Published)


Forde, P. F., Hall, L. J., Sadadcharam, M., de Kruijf, M., O’ Sullivan, G. C., Soden, D. M.

(2014)

Development and characterization of an enhanced nonviral expression vector for electroporation cancer treatment,

in Molecular Therapy — Methods & Clinical Development

1

article no. 14012

Full Text UEA Repository

(Article)

(Published)


Forde, P. F., Sadadcharam, M., Hall, L. J., O'Donovan, T. R., de Kruijf, M., Byrne, W. L., O'Sullivan, G. C., Soden, D. M.

(2014)

Enhancement of electroporation facilitated immunogene therapy via T-reg depletion,

in Cancer Gene Therapy

21

pp. 349-354

Full Text UEA Repository

(Article)

(Published)


Williams, J. M., Duckworth, C. A., Watson, A. J. M., Frey, M. R., Miguel, J. C., Burkitt, M. D., Sutton, R., Hughes, K. R., Hall, L. J., Caamaño, J. H., Campbell, B. J., Pritchard, D. M.

(2013)

A mouse model of pathological small intestinal epithelial cell apoptosis and shedding induced by systemic administration of lipopolysaccharide,

in Disease Models & Mechanisms

6

(6)

pp. 1388-1399

Full Text UEA Repository

(Article)

(Published)


Hall, L., Murphy, C., Quinlan, A., Hurley, G., Shanahan, F., Nally, K., Melgar, S.

(2013)

Natural killer cells protect mice from DSS-induced colitis by regulating neutrophil function via the NKG2A receptor,

in Mucosal Immunology

6

pp. 1016-1026

Full Text UEA Repository

(Article)

(Published)


Watson, A., Hall, L.

(2013)

Regulation of host gene expression by gut microbiota,

in Gastroenterology

144

(4)

pp. 841-4

UEA Repository

(Article)

(Published)


Hall, L., Murphy, C., Hurley, G., Quinlan, A., Shanahan, F., Nally, K., Melgar, S.

(2013)

Natural Killer cells protect against mucosal and systemic infection with the enteric pathogen Citrobacter rodentium,

in Infection and Immunity

81

(2)

pp. 460-469

Full Text UEA Repository

(Article)

(Published)


Watson, A. J. M., Hall, L. J., Hughes, K. R.

(2012)

Cell shedding: old questions answered,

in Gastroenterology

143

(5)

pp. 1389-1391

Full Text UEA Repository

(Article)

(Published)


Fanning, S., Hall, L., van Sinderen, D.

(2012)

Bifidobacterium breve UCC2003 surface exopolysaccharide production is a beneficial trait mediating commensal-host interaction through immune modulation and pathogen protection.,

in Gut Microbes

3

(5)

pp. 420-5

Full Text UEA Repository

(Article)

(Published)


Hall, L. J., Watson, A. J. M.

(2012)

Role of autophagy in NOD2-induced inflammation in Crohn's disease,

in Gastroenterology

142

(4)

pp. 1032-1034

Full Text UEA Repository

(Article)

(Published)


Fanning, S., Hall, L., Cronin, M., Zomer, A., MacSharry, J., Goulding, D., O'Connell Motherway, M., Shanahan, F., Nally, K., Dougan, G., van Sinderen, D.

(2012)

Bifidobacterial surface-exopolysaccharide facilitates commensal-host interaction through immune modulation and pathogen protection,

in Proceedings of the National Academy of Sciences

109

(6)

pp. 2108-2113

Full Text UEA Repository

(Article)

(Published)


Murphy, C., Hall, L., Hurley, G., Quinlan, A., MacSharry, J., Shanahan, F., Nally, K., Melgar, S.

(2012)

The Sphingosine-1-Phosphate Analogue FTY720 Impairs Mucosal Immunity and Clearance of the Enteric Pathogen Citrobacter rodentium,

in Infection and Immunity

80

(8)

pp. 2712-2723

Full Text UEA Repository

(Article)

(Published)


Dougan, G., Goulding, D., Hall, L.

(2011)

Live Vaccines and Their Role in Modern Vaccinology,

in Replicating Vaccines: A New Generation.

Springer

pp. 3-14

ISBN 978-3-0346-0276-1

UEA Repository

(Chapter)

(Published)


Jansen, A., Hall, L., Clare, S., Goulding, D., Holt, K., Grant, A., Mastroeni, P., Dougan, G., Kingsley, R.

(2011)

A Salmonella Typhimurium-Typhi genomic chimera: A murine-typphoid model to study Vi polysaccharide capsule function,

in PLoS Pathogens

7

(7)

article no. e1002131

Full Text UEA Repository

(Article)

(Published)


Hall, L., Clare, S., Dougan, G.

(2010)

NK cells influence both innate and adaptive immune responses after mucosal immunization with antigen and mucosal adjuvant,

in Journal of Immunology

184

(8)

pp. 4327-4337

UEA Repository

(Article)

(Published)


Hall, L., Clare, S., Dougan, G.

(2010)

Probing local innate immune responses after mucosal immunisation,

in Journal of Immune Based Therapies and Vaccines

8

(5)

UEA Repository

(Article)

(Published)


Hall, L., Faivre, E., Quinlan, A., Shanahan, F., Nally, K., Melgar, S.

(2010)

Induction and activation of adaptive immune populations during acute and chronic phases of a murine model of experimental colitis,

in Digestive Diseases and Sciences

56

(1)

pp. 79-89

UEA Repository

(Article)

(Published)


<- Page 1 of 2 ->

Key Research Interests

Research Themes

Please see www.Halllab.co.uk for our current research areas

Teaching Interests

Dr Hall is currently primary supervisor to 5 PhD students, and also secondary supervisor to 3 PhD students 

 

Professional Activities

Dr Hall is on the Wellcome Trust Basic Science Fellowship Committee