Biography

Lee's research focuses on supporting older people to eat and drink well, and she is a dietitian, nutritionist and systematic reviewer.  Her current research (initiated during her National Institute for Health Research Career Development Fellowship) is on preventing and identifying dehydration in older people living in residential (long-term) care.  See http://driestudy.appspot.com/ for details of the DRIE (Dehydration Recognition In our Elders) Study.

Lee has a long term interest in the nutrition and hydration of older people. She is an expert systematic reviewer and has developed and managed many systematic reviews. Lee has been an editor for the Cochrane Heart Group for 14 years, was an editor of the Cochrane Oral Health Group for 5 years, and regularly referees systematic reviews for top medical and nutrition journals.

Lee is a Reader in Research Synthesis, Nutrition & Hydration in the Norwich Medical School at the University of East Anglia and has a BSc in Biochemistry, PhD (University of Manchester) and current dietetic registration. She worked as a dietitian in the National Health Service for ten years, with extensive experience of community health promotion and cardiovascular health. Lee moved to research in 2000 and has since published over 80 peer-reviewed publications, mainly in the areas of dehydration and nutrition of older people and the effects of dietary change on health. Her publications have been cited almost 3000 times (with an average citation per publication of over 33, and h-index of 29).

Lee is a member of the World Health Organization Nutrition Guidance Expert Advisory Group (NUGAG) on Diet and Health, which has recently produced guidance on sodium and potassium intakes. As well as being a Cochrane editor, she is an editor of Quality in Ageing and Older Adults, was awarded Ibex Award by British Dietetic Association (2005), and was a member of the National Institute for Clinical Excellence (NICE) Partners Council.

Career History

Reader in Research Synthesis & Nutrition, August 2014 - present, University of East Anglia

Senior Lecturer in Research Synthesis & Nutrition, August 2008 -present, University of East Anglia

Lecturer in Evidence Synthesis & Nutrition, Jan 2005 –July 2008, University of East Anglia

Lecturer in Evidence Based Care & Systematic Review, Nov 2002-Jan 2005, University of Manchester

Research Associate in Evidence Based Care & Systematic Review, Nov 1999-Oct 2002, University of Manchester

Heart Health Dietitian, Senior I, Apr 1996–Nov 1999, Princess Royal Hospital, Apley Castle, Telford. Clinical role in vascular health promotion & cardiac rehabilitation across Shropshire plus systematic review research.

Heart Health Dietitian, Senior I, Sept 1989-March 1996, dietetic posts in Shropshire, incl. Health Promotion, hospital ward-based and out-patient based work in mental health and cardiovascular disease prevention.

Work for Suffolk Trust for Nature Conservation (coppicing and running a team of work experience lads in Bradfield Woods) and self-employment (making split oak lathes for re-roofing ancient buildings), 1982-1986.

Care assistant in 2 Norfolk Homes for the Elderly, Norfolk County Council and a private home, 1981-2.  

Academic Background

  • PhD, University of Manchester, 2005, Systematic reviews in diet and cardiovascular disease
  • Member of the Higher Education Academy, 2001- present
  • Diploma in Systematic Reviews Methodology, 1998, UCL & Royal Free Hospital
  • Diploma in Advanced Dietetic Practice, 1999, British Dietetic Association, Birmingham
  • Diploma in Dietetics, with distinction, 1989, Leeds Polytechnic
  • B.Sc. Biochemistry (second class honours, division one), 1981, University of East Anglia

All Publications

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Kintz, E., Brainard, J., Hooper, L., Hunter, P.

(2017)

Transmission pathways for sporadic Shiga-toxin producing E. coli infections: A systematic review and meta-analysis

in International Journal of Hygiene and Environmental Health

220.

pp. 57–67

Full Text UEA Repository

(Article)


Howard Wilsher, S., Irvine, L., Fan, H., Shakespeare, T., Suhrcke, M., Horton, S., Poland, F., Hooper, L., Song, F.

(2016)

Systematic overview of economic evaluations of health-related rehabilitation

in Disability and Health Journal

9.

pp. 11-25

Full Text UEA Repository

(Article)


Hooper, L., Bunn, D., Downing, A., Jimoh, F., Groves, J., Free, C., Cowap, V., Potter, J., Hunter, P., Shepstone, L.

(2016)

Which frail older people are dehydrated? The UK DRIE study

in The Journal of Gerontology: Medical Sciences

71.

pp. 1341-1347

Full Text UEA Repository

(Article)


Hooper, L., Mann, J.

(2016)

Observational studies are compatible with an association between saturated and trans fats and cardiovascular disease

in Evidence-Based Medicine

21.

pp. 37

Full Text UEA Repository

(Article)


Brainard, J., Hooper, L., Pond, K., Edmunds, K., Hunter, P. R.

(2016)

Risk factors for transmission of Ebola or Marburg virus disease: a systematic review and meta-analysis

in International Journal of Epidemiology

45.

Full Text UEA Repository

(Article)


Abdelhamid, A., Bunn, D. K., Copley, M., Cowap, V., Dickinson, A., Gray, L., Howe, A., Killett, A., Lee, J., Li, F., Poland, F., Potter, J. F., Richardson, K., Smithard, D., Fox, C., Hooper, L.

(2016)

Effectiveness of interventions to directly support food and drink intake in people with dementia: systematic review and meta-analysis

in BMC Geriatrics

16.

Full Text UEA Repository

(Article)


Hooper, L.

(2016)

Why, oh why, are so many older adults not drinking enough fluid?

in Journal of the Academy of Nutrition and Dietetics

116.

pp. 774–778

Full Text

(Editorial)


Brainard, J., Pond, K., Hooper, L., Edmunds, K., Hunter, P.

(2016)

Presence and Persistence of Ebola or Marburg Virus in Patients and Survivors: A Rapid Systematic Review

in PLoS Neglected Tropical Diseases

10.

Full Text UEA Repository

(Article)


Hooper, L., Bunn, D. K., Abdelhamid, A., Gillings, R., Jennings, A., Maas, K., Millar, S., Twomlow, E., Hunter, P. R., Shepstone, L., Potter, J. F., Fairweather-Tait, S. J.

(2016)

Water-loss (intracellular) dehydration assessed using urinary tests, how well do they work? Diagnostic accuracy in older people

in American Journal of Clinical Nutrition

104.

pp. 121-131

Full Text UEA Repository

(Article)


Bunn, D., Abdelhamid, A., Copley, M., Cowap, V., Dickinson, A., Howe, A., Killett, A., Poland, F., Potter, J., Richardson, K., Smithard, D., Fox, G., Hooper, L.

(2016)

Effectiveness of interventions to indirectly support food and drink intake in people with dementia: Eating and Drinking Well IN dementiA (EDWINA) systematic review

in BMC Geriatrics

16.

Full Text UEA Repository

(Article)


Abdelhamid, A., Martin, N., Bridges, C., Song, F., Deane, K. H., Hooper, L.

(2016)

Polyunsaturated fat intake for prevention of cardiovascular disease

in Cochrane Database of Systematic Reviews

Full Text

(Scientific review)


Siervo, M., Prado, C., Hooper, L., Munro, A., Collerton, J., Davies, K., Kingston, A., Mathers, J., Kirkwood, T., Jagger, C.

(2015)

Serum osmolarity and haematocrit do not modify the association between the impedance index (Ht2/Z) and total body water in the very old: The Newcastle 85+ Study

in Archives of Gerontology and Geriatrics

60.

pp. 227–232

Full Text UEA Repository

(Article)


Jimoh, F., Bunn, D., Hooper, L.

(2015)

Assessment of a self-reported Drinks Diary for the estimation of drinks intake by care home residents: Fluid Intake Study in the Elderly (FISE)

in Journal of Nutrition, Health and Aging

19.

pp. 491-496

Full Text UEA Repository

(Article)


Bunn, D., Jimoh, F., Howard Wilsher, S., Hooper, L.

(2015)

Increasing fluid intake and reducing dehydration risk in older people living in long-term care: a systematic review

in Journal of the American Medical Directors Association

16.

pp. 101-113

Full Text UEA Repository

(Article)


Hooper, L., Abdelhamid, A., Attreed, N. J., Campbell, W. W., Channell, A. M., Chassagne, P., Culp, K. R., Fletcher, S. J., Fortes, M. B., Fuller, N., Gaspar, P. M., Gilbert, D. J., Heathcote, A. C., Kafri, M., Kajii, F., Lindner, G., Mack, G. W., Mentes, J. C., Merlani, P., Needham, R., Olde Rikkert, M. G., Perren, A., Powers, J., Ranson, S., Ritz, P., Rowat, A. M., Sjostrand, F., Smith, A. C., Stookey, J. J., Stotts, N. A., Thomas, D. R., Vivanti, A., Wakefield, B. J., Waldreus, N., Walsh, N. P., Ward, S., Potter, J. F., Hunter, P.

(2015)

Clinical and physical signs for identification of impending and current water-loss dehydration in older people

in Cochrane Database of Systematic Reviews

Full Text UEA Repository

(Article)


Hooper, L., Whitelock, S., Bunn, D.

(2015)

Reducing dehydration in residents of care homes

in Nursing Times

111.

pp. 16-19

UEA Repository

(Article)


Bunn, D., Hooper, L.

(2015)

Detecting dehydration in older people: useful tests

in Nursing Times

111.

pp. 12-16

UEA Repository

(Article)


Hooper, L., Martin, N., Abdelhamid, A., Davey Smith, G.

(2015)

Reduction in saturated fat intake for cardiovascular disease

in Cochrane Database of Systematic Reviews

2015.

pp. 1

Full Text UEA Repository

(Article)


Hooper, L., Abdelhamid, A., Bunn, D., Brown, T., Summerbell, C., Skeaff, M.

(2015)

Effects of total fat intake on body weight

in Cochrane Database of Systematic Reviews

2015.

Full Text UEA Repository

(Article)


Hooper, L., Martin, N., Abdelhamid, A.

(2015)

Cochrane Corner: what are the effects of reducing saturated fat intake on cardiovascular disease and mortality?

in Heart

101.

pp. 1938-1940

Full Text

(Editorial)


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Key Research Interests

Diagnosis of early dehydration in older people (http://driestudy.appspot.com/)

Systematic reviewing

Diet and cardiovascular health

Food and older people (see http://cafe-project.appspot.com/ and http://cafe-project.appspot.com/)

Selected Publications:

  • Citation Metrics: Sum of citations >2900, Articles with citation data >80, Average citations per article >33, h-index 29 (to April 2015)
  • For up-to-date full publication list and citation metrics see http://www.researcherid.com/rid/D-2795-2009

Research Keywords:

DehydrationHydration
Systematic reviewEvidence synthesis
NutritionElderly
Cardiovascular diseaseDiagnostic accuracy

Postgraduate Research Student Supervision:

Dehydration in older peopleCare homes research
Fluid intake in older peopleNutrition in older people
Systematic reviewsDiet and cardiovascular disease

Current Research Projects & Grants:

  • £74,869. Dunhill Medical Trust.  Creating a “pro-drinking” environment: developing & testing an innovative low-cost activity-based intervention to support care home residents in keeping hydrated(a proof of concept study).  PI: L Hooper, CO-Is D Bunn, A Killett, T Backhouse, F Cheater, P Hunter, L Shepstone. July 2015 to Dec 2016.  Lee developed the concept, worked with the co-Is to write the application and is PI.

  • £13,317. NHS England.  Analysis of the diagnostic accuracy of urinary measures to predict dehydration in older people.  PI: L Hooper. Nov 2014 to May 2015.  Lee wrote the application and is PI.

  • £11,937. NHS England.  Diagnostic accuracy of calculated serum osmolarity to predict dehydration in older people. PI: L Hooper. Nov 2014 to May 2015.  Lee wrote the application and is PI.

  • £21,752. World Health Organization.  Updating a systematic review on the effects of fat intake on weight.  PI: L Hooper. Nov 2014 to Sept 2015.  Lee wrote the application and is PI.

  • £50,000. NIHR CLAHRC East of England.  Eating and Drinking Well IN dementiA (EDWINA).  PI: L Hooper. Jan – Nov 2014.  Lee wrote the application and is PI.

  • £495,000.  NIHR Career Development Fellowship.  Development of a simple tool for use by older people and carers for diagnosis of impending water-loss dehydration in the community. PI: L Hooper.  Jan 2012-March 2015.  Personal fellowship – Lee wrote the application and is carrying out the research.

  • £4,000,000.  NIHR Health Protection Research Unit (HPRU),  Emergency Preparedness and Response.  PI P Hunter and colleagues from University of Newcastle, Lee is a co-applicant.  Will run from 2014 to 2019. 

  • £2,006,699.  NIHR Health Protection Research Unit (HPRU) Gastrointestinal Infections.  PI Paul Hunter and colleagues from University of Liverpool and Institute for Food Research, Lee is a co-applicant.  Will run from 2014 to 2019.

  • £41,468.  World Health Organization.  Systematic review on health economics of rehabilitation. PI: F Song, Lee is a co-applicant.  Sept 2013 to March 2014.

  • £102,562. European Food Safety Authority. Literature search and review related to specific preparatory work in the establishment of Dietary Reference Values. PI: S Fairweather-Tait, co-applicants L Hooper, L Harvey, R Collings. Jan-Dec 2011. Co-wrote the application (project was out for tender), will train RAs to carry out the review.
  • €1000. European Hydration Institute. Hydration status following stroke and the relationship between hydration and functional status at discharge. PI Mohannad Kafri, co-applicant (supervisor) L Hooper. March – Dec 2011. Co-wrote application, provides additional funding for Mohannad’s PhD work.
  • £42,558. What is the evidence of the impact of micro-credit on the incomes of poor people? PI Richard Palmer Jones. May 2010-Feb 2011. Co-wrote the application, supporting development of systematic review skills in DEV at UEA.
  • £49,982. The effects of the transfer of common property to private ownership. PI Thomas Sikor. June 2010-Jan 2011. Co-wrote the application, supporting development of systematic review skills in DEV at UEA.
  • £76,754. Barry Callebaut. Effects of chocolate and cocoa on markers of oxidative stress: a systematic review of randomised controlled trials. PI: Lee Hooper. Dec 2009-August 2010.
  • £24,983. Food Standards Agency. A systematic review of the effects of climate change on food within the remit of the Food Standards Agency PI: Iain Lake. June 2009-Sept 2009.
  • £396,250. EC (FP6) EURRECA – Network of Excellence. PI: Fairweather-Tait. Jan 2007- Dec 2011.
  • £30,603. Norfolk Primary Care Trust. Community Health Needs Assessment for Thetford Healthy Town. PI: Rechel. June 2009-Nov 2009.
  • £37,725. Soy Nutrition Institute. Effects of soy and isoflavones on hormonal status in women: a systematic review. PI: Hooper. Oct 2007-July 2008. £79,124 Economic and Social Research Council. CAFÉ - Changes Around Food Experience (Impact of reduced contact with food on social engagement & wellbeing of older women). PI: Hooper. Apr 2007-Mar 2008.
  • £44,005 Norfolk County Council. Change in food and drink provision in homes for the elderly: effects on health and wellbeing. PI: Hooper, July 2006- Dec 2007.
  • £93,112 Health Technology Assessment Research Methodology Programme. Dissemination biases in medical and health related research - an updated synthesis of empirical evidence and a critical assessment of available methods. PI Fujian Song. Sept 2007 to August 2008.

External Activities and Indicators of Esteem

  • Lee is a member of the World Health Organization Nutrition Guidance Expert Advisory Group (NUGAG) Subgroup on Diet and Health, participating in production of dietary guidance for WHO (2012 to 2014)
  • She supported the World Health Organization Nutrition Guidance Expert Advisory Group (NUGAG) Subgroup on Diet and Health as a resource person in production of dietary guidance (2010 to 2012)
  • Lee is on the editorial board of The Cochrane Heart Group (2001 to present)
  • She is on the editorial board of Quality in Ageing and Older Adults (2010 to present)
  • Lee is the external examiner for the MRes in Human Nutrition course, Imperial College (2011 to present)
  • Lee was on the editorial board of The Cochrane Oral Health Group (2004 to 2008)
  • She was guest editor of an American Journal of Clinical Nutrition supplement, Biomarkers of Micronutrient Status: EURRECA Workshop. Supplement to volume 89 (2009)
  • Work in over 60 care homes in Norfolk and Suffolk teaching residents, staff and family members about dehydration in older people (2012 to 2015)
  • Seminar on identifying and preventing dehydration in older people for dietitians working with older people (19th Oct 2013)

Professional Activities

  • Awarded Ibex Award by British Dietetic Association for development of evidence base for nutrition and dietetics, 2005
  • Member Consensus Reference Group of NICE Chronic Heart Failure Guideline development group, 2002-3

Administrative Posts

  • Lee’s main administrative role was to coordinate the Diet and Health Spiral Curriculum within the MBBS programme.
  • She developed, ran and delivered the Research Synthesis Module of the MRes in Health Research.
  • Lee was the Plagiarism Officer for the School of Medicine, Health Policy and Practice (from 2006 to March 2009).
  • From March 2009 to December 2011 she was responsible for running the third year of the Research Module for undergraduate medical students.
  • Lee established the successful East Anglian Research Synthesis Network (EARS).
  • Research Associate Coordinator for MED