All Publications

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Nimmagadda, S. C., Frey, S., Edelmann, B., Hellmich, C., Zaitseva, L., König, G. M., Kostenis, E., Bowles, K. M., Fischer, T.

(2017)

Bruton's Tyrosine Kinase and RAC1 promote cell survival in MLL-rearranged acute 1 myeloid leukemia,

in Leukemia

Full Text UEA Repository

(Article)

(E-pub ahead of print)


Sun, Y., Abdul Aziz, A., Bowles, K., Rushworth, S.

(2018)

High NRF2 expression controls endoplasmic reticulum stress induced apoptosis in multiple myeloma,

in Cancer Letters

412

pp. 37-45

Full Text UEA Repository

(Article)

(E-pub ahead of print)


Marlein, C. R., Zaitseva, L., Piddock, R. E., Robinson, S., Edwards, D., Shafat, M. S., Zhou, Z., Lawes, M., Bowles, K. M., Rushworth, S. A.

(2017)

NADPH oxidase-2 derived superoxide drives mitochondrial transfer from bone marrow stromal cells to leukemic blasts,

in Blood

130

(14)

pp. 1649-1660

Full Text UEA Repository

(Article)

(Published)


Barlas, R. S., McCall, S. J., Bettencourt-Silva, J. H., Clark, A. B., Bowles, K. M., Metcalf, A. K., Mamas, M. A., Potter, J. F., Myint, P. K.

(2017)

Impact of anaemia on acute stroke outcomes depends on the type of anaemia: Evidence from a UK stroke register,

in Journal of the Neurological Sciences

383

pp. 26-30

Full Text UEA Repository

(Article)

(E-pub ahead of print)


Foster, E. J., Barlas, R. S., Wood, A. D., Bettencourt-Silva, J. H., Clark, A. B., Metcalf, A. K., Bowles, K. M., Potter, J. F., Myint, P. K.

(2017)

A History of Falls is Associated with a Significant Increase in Acute Mortality in Women after Stroke,

in Journal of Clinical Neurology

13

(4)

pp. 411-421

Full Text UEA Repository

(Article)

(Published)


Shafat, M. S., Gnaneswaran, B., Bowles, K. M., Rushworth, S. A.

(2017)

The bone marrow microenvironment – Home of the leukemic blasts,

in Blood Reviews

31

(5)

pp. 277–286

Full Text UEA Repository

(Article)

(Published)


Griffin, J. C., Sadullah, S., Igali, L., Shah, N. K., Wimperis, J. Z., Bowles, K. M.

(2017)

Nodular Lymphocyte Predominant Hodgkin Lymphoma: A Real-world Case Series of Consecutive Patients Treated by a Single Multidisciplinary Team in the East of England From 1999 to 2015,

in Clinical Lymphoma, Myeloma and Leukemia

Full Text UEA Repository

(Article)

(E-pub ahead of print)


Curtain, J. P., Yu, M., Clark, A. B., Gollop, N. D., Bettencourt-Silva, J. H., Metcalf, A. K., Bowles, K. M., Flather, M. D., Potter, J. F., Myint, P. K.

(2017)

Determinants of Length of Stay Following Total Anterior Circulatory Stroke,

in BMC Geriatrics

2

(3)

article no. 26

Full Text UEA Repository

(Article)

(Published)


Chandran, S., Watkins, J., Abdul‐Aziz, A., Shafat, M., Calvert, P. A., Bowles, K. M., Flather, M. D., Rushworth, S. A., Ryding, A. D.

(2017)

Inflammatory Differences in Plaque Erosion and Rupture in Patients With ST‐Segment Elevation Myocardial Infarction,

in Journal of the American Heart Association

6

(5)

article no. e005868

Full Text UEA Repository

(Article)

(Published)


Adekunle-Olarinde, I. R., McCall, S. J., Barlas, R. S., Wood, A. D., Clark, A. B., Bettencourt-Silva, J. H., Metcalf, A. K., Bowles, K. M., Soiza, R. L., Potter, J. F., Myint, P. K.

(2017)

Addition of sodium criterion to SOAR stroke score,

in Acta Neurologica Scandinavica

135

(5)

pp. 553–559

Full Text UEA Repository

(Article)

(Published)


Piddock, R. E., Bowles, K. M., Rushworth, S. A.

(2017)

The Role of PI3K Isoforms in Regulating Bone Marrow Microenvironment Signaling Focusing on Acute Myeloid Leukemia and Multiple Myeloma,

in Cancers

9

(4)

article no. 29

Full Text UEA Repository

(Article)

(Published)


Eyre, T., Osborne, W., Gallop-Evans, E., Ardeshna, K., Kassam, S., Sadullah, S., Sidra, G., Culligan, D., Arumainathan, A., Shankara, P., Bowles, K., Eyre, D., Peng, Y., Pettengell, R., Bloor, A., Vandenberghe, E., Collins, G.

(2017)

Results of a multicentre UK-wide compassionate use programme evaluating the efficacy of idelalisib monotherapy in relapsed, refractory follicular lymphoma,

in British Journal of Haematology

Full Text UEA Repository

(Article)

(E-pub ahead of print)


Piddock, R. E., Loughran, N., Marlein, C. R., Robinson, S. D., Edwards, D. R., Yu, S., Pillinger, G. E., Zhou, Z., Zaitseva, L., Auger, M. J., Rushworth, S. A., Bowles, K. M.

(2017)

PI3Kδ and PI3Kγ isoforms have distinct functions in regulating pro-tumoural signalling in the multiple myeloma microenvironment,

in Blood Cancer Journal

7

(3)

article no. e539

Full Text UEA Repository

(Article)

(Published)


Shafat, M. S., Oellerich, T., Mohr, S., Robinson, S. D., Edwards, D. R., Marlein, C. R., Piddock, R. E., Fenech, M., Zaitseva, L., Abdul-Aziz, A., Turner, J., Watkins, J. A., Lawes, M., Bowles, K. M., Rushworth, S. A.

(2017)

Leukemic blasts program bone marrow adipocytes to generate a protumoral microenvironment,

in Blood

129

(10)

pp. 1320-1332

Full Text UEA Repository

(Article)

(Published)


Abdul-Aziz, A., Shafat, M., Mehta, T., Di Palma, F., Lawes, M., Rushworth, S. A., Bowles, K.

(2017)

MIF-induced stromal PKCβ/IL8 is essential in human acute myeloid leukemia,

in Cancer Research

77

(2)

pp. 303-311

Full Text UEA Repository

(Article)

(Published)


Jacob, A., Bloor, A., Whiteway, A., Milne, A., Kirkwood, A., Hodson, A., Duncombe, A., Schuh, A., von Barsewisch, B., Fegan, C., Fox, C., Pocock, C., William, C., Dearden, C., Hutchinson, C., Balotis, C., De Lord, C., Kennedy, D., Tucker, D., Vendenberghe, E., Maughan, E., Kumar, E., McNichol, F., Scott, F., Forconi, F., Campbell, G., Follows, G., Pratt, G., Knight, H., Parry, H., Ringshausen, I., Whalley, I., Nielson, J., Allen, J., Arnold, J., Gribbon, J., Wallis, J., Blundell, J., Cwynarski, K., Bowles, K., Ewings, M., Karanth, M., Dyer, M., Hamblin, M., Leach, M., Badat, M., Mir, N., Morley, N., Bienz, N., Philpott, N., Parry-Jones, N., Jasani, P., Thornton, P., Cervi, P., Micallef-Eynaud, P., Moss, P., Kaczmarek, P., Cumber, P., Hillmen, P., Patten, P., Boulton-Jones, R., Murrin, R., Noble, R., Marcus, R., Agrawal, S., Narat, S., Janes, S., Updyke, S., Marshall, S., Sadullah, S., Paneesha, S., Rule, S., Wagner, S., Glavey, S., Bowcock, S., Devereux, S., Kaul, S., Kundu, S., Iyengar, S., Munir, T., Eyre, T., Sorour, Y.

(2016)

Ibrutinib for Relapsed / Refractory CLL: A UK and Ireland Analysis of Outcomes in 315 patients,

in Haematologica

101

(12)

pp. 1563-1572

Full Text UEA Repository

(Article)

(Published)


Wood, A. D., Gollop, N. D., Bettencourt-Silva, J. H., Clark, A. B., Metcalf, A. K., Bowles, K. M., Flather, M. D., Potter, J. F., Myint, P. K.

(2016)

A 6-point TACS score predicts in-hospital mortality following total anterior circulation stroke,

in Journal of Clinical Neurology

12

(4)

pp. 407-413

Full Text UEA Repository

(Article)

(Published)


Wittmann, A., Lamprinaki, D., Bowles, K. M., Katzenellenbogen, E., Knirel, Y. A., Whitfield, C., Nishimura, T., Matsumoto, N., Yamamoto, K., Iwakura, Y., Saijo, S., Kawasaki, N.

(2016)

Dectin-2 recognises mannosylated O-antigens of human opportunistic pathogens and augments lipopolysaccharide activation of myeloid cells,

in Journal of Biological Chemistry

291

(34)

pp. 17629-17638

Full Text UEA Repository

(Article)

(Published)


Barlas, R. S., Honney, K., Loke, Y. K., McCall, S. J., Bettencourt-Silva, J. H., Clark, A. B., Bowles, K. M., Metcalfe, A. K., Mamas, M. A., Potter, J. F., Myint, P. K.

(2016)

Impact of hemoglobin levels and anemia on mortality in acute stroke: analysis of UK regional registry data, systematic review and meta-analysis,

in Journal of the American Heart Association

5

(8)

article no. e003019

Full Text UEA Repository

(Article)

(Published)


Pillinger, G., Loughran, N. V., Piddock, R. E., Shafat, M. S., Zaitseva, L., Abdul-Aziz, A., Lawes, M. J., Bowles, K. M., Rushworth, S. A.

(2016)

Targeting PI3Kδ and PI3Kγ signalling disrupts human AML survival and bone marrow stromal cell mediated protection,

in Oncotarget

7

(26)

pp. 39784-39795

Full Text UEA Repository

(Article)

(Published)


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