Biography

Jonathan Tang BSc. MSc. FIBMS

Jonathan Tang graduated from Biomedical Science at the Liverpool John Moores University with BSc (hons). He undertook training to become HCPC registered Biomedical Scientist in the Biochemistry Department of the Royal Liverpool University Hospital while completing his Master degree at the Manchester Metropolitan University. During the ten years working in a busy NHS hospital laboratory he specialised in the analytical technique of high performance liquid chromatography (HPLC) for the analysis of drugs and proteins. He was responsible for the introduction and expansion of the liquid chromatography tandem mass spectrometry (LC-MS/MS) laboratory. During his time at Liverpool he introduced a number of routine assays including urine drugs of abuse, immunosuppressants, vitamin D and steroid hormones. In 2004 he obtained fellowship from the Institute of Biomedical Science and was promoted to senior section manager of the LC-MS/MS laboratory.

In 2011 Jon took up the role as the Bioanalytical facility manager at the University of East Anglia. Working closely with Professor Bill Fraser, he established a multidisciplinary, CPA accredited facility within the university environment while working collaboratively with Norfolk and Norwich University NHS hospital to form a unique Supra regional assay and advisory service (SAAS), providing an analytical service for bone and calcium homeostasis related markers. His current research focuses on the development of LC-MS/MS techniques to measure vitamin D metabolites (1, 25 dihydroxy vitamin D and 24, 25 dihydroxy vitamin D) and the study of their relationships in health and in disease. 

All Publications

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Macdonald, H., Gryka, A., Tang, J., Aucott, L., Fraser, W., Wood, A.

(2017)

Longevity of daily oral Vitamin D3 supplementation: Differences in 25OHD and 24,25(OH)2D observed 2 years after cessation of a 1-year randomized controlled trial (VICtORy RECALL),

in Osteoporosis International

28

(12)

pp. 3361–3372

Full Text UEA Repository

(Article)

(Published)


Papageorgiou, M., Elliott-Sale, K. J., Parsons, A., Tang, J., Greeves, J. P., Fraser, W. D., Sale, C.

(2017)

Effects of reduced energy availability on bone metabolism in women and men,

in Bone

105

pp. 191-199

Full Text UEA Repository

(Article)

(Published)


Al Riyami, S., Tang, J. C. Y., Galitzer, H., Fraser, W.

(2017)

LC-MS/MS measurement of parathyroid hormone PTH (1-34): Use in studying oral PTH (1-34) administration and possible diagnostic application in pseudohypoparathyroidism.,

Full Text

(Poster)

(Published)


Earl, K. E., Sakellariou, G. K., Sinclair, M., Fenech, M., Croden, F., Owens, D. J., Tang, J., Miller, A., Lawton, C., Dye, L., Close, G. L., Fraser, W. D., McArdle, A., Beadsworth, M. B. J.

(2017)

Vitamin D status in chronic fatigue syndrome/myalgic encephalomyelitis: a cohort study from the North-West of England,

in BMJ Open

7

article no. e015296

Full Text UEA Repository

(Article)

(Published)


Saleh, L., Tang, J. C., Gawinecka, J., Boesch, L., Fraser, W. D., von Eckardstein, A., Nowak, A.

(2017)

Impact of a single oral dose of 100,000 IU vitamin D3 on profiles of serum 25(OH)D3 and its metabolites 24,25(OH)2D3, 3-epi-25(OH)D3, and 1,25(OH)2D3 in adults with vitamin D insufficiency,

in Clinical Chemistry and Laboratory Medicine

55

(12)

pp. 1912-1921

Full Text UEA Repository

(Article)

(Published)


Hanusch, B., Tuck, S., McNally, R., Wu, J., Prediger, M., Walker, J., Tang, J., Piec, I., Fraser, W., Datta, H., Francis, R.

(2017)

Does regional loss of bone density explain low trauma distal forearm fractures in men (the Mr F study)?,

in Osteoporosis International

28

(10)

pp. 2877–2886

Full Text UEA Repository

(Article)

(Published)


Burstein, G., Tang, J. C. Y., Rothner, A., Galitzer, H., Schwartz, P., Fraser, W.

(2017)

Enhanced bioavailability and reduced pharmacokinetic variability of Oral PTH (1-34) in man,

(Poster)

(Published)


Al Riyami, S., Tang, J. C. Y., Dutton, J., Washbourne, C., Galitzer, H., Fraser, W.

(2017)

Development and Validation of a LC-MS/MS Assay for Quantification of Parathyroid Hormone (PTH 1-34) in human Plasma,

(Poster)

(Published)


Al Riyami, S., Tang, J. C. Y., Galitzer, H., Fraser, W.

(2017)

Measurements of Osteoanabolic agents PTH (1-34) and PTHrP (1-36) in therapeutic studies and clinical diagnostics,

(Poster)

(Published)


Piec, I., Dutton, J., Al Riyami, S., Washbourne, C., Schoenmakers, I., Galitzer, H., Burshtein, G., Schwartz, P., Tang, J. C. Y., Fraser, W.

(2017)

A LC-MS/MS method for the diagnostic measurement of cAMP in plasma and urine,

(Poster)

(Published)


Tang, J. C. Y., Nicholls, H., Ball, N., Dutton, J., Piec, I., Rudge, J., Washbourne, C., Fraser, W.

(2017)

Assessment of vitamin D status using MitraTM volumetric absorptive microsampling (VAMS) device,

(Poster)

(Published)


Tang, J. C. Y., Nicholls, H., Piec, I., Washbourne, C. J., Dutton, J. J., Jackson, S., Greeves, J., Fraser, W. D.

(2017)

Reference intervals for serum 24,25-Dihydroxyvitamin D and the ratio with 25-Hydroxyvitamin established using a newly developed LC-MS/MS method,

in Journal of Nutritional Biochemistry

46

pp. 21–29

Full Text UEA Repository

(Article)

(Published)


Townsend, R., Elliott-Sale, K. J., Currell, K., Tang, J., Fraser, W. D., Sale, C.

(2017)

The Effect of Postexercise Carbohydrate and Protein Ingestion on Bone Metabolism,

in Medicine & Science in Sports & Exercise

49

(6)

pp. 1209-1218

Full Text UEA Repository

(Article)

(Published)


Cleal, J. K., Hargreaves, M. R., Poore, K. R., Tang, J. C. Y., Fraser, W. D., Hanson, M. A., Green, L. R.

(2017)

Reduced fetal vitamin D status by maternal undernutrition during discrete gestational windows in sheep,

in Journal of Developmental Origins of Health and Disease

8

(3)

pp. 370-381

Full Text UEA Repository

(Article)

(Published)


Peel, A. M., Crossman-Barnes, C., Tang, J., Fowler, S., Davies, G., Wilson, A., Loke, Y.

(2017)

Biomarkers in adult asthma: a systematic review of 8-isoprostane in exhaled breath condensate,

in Journal of Breath Research

11

(1)

article no. 016011

Full Text UEA Repository

(Article)

(Published)


Owens, D. J., Tang, J. C. Y., Bradley, W. J., Sparks, S. A., Fraser, W. D., Morton, J. P., Close, G. L.

(2017)

Efficacy of High-Dose Vitamin D Supplements for Elite Athletes,

in Medicine and Science in Sports and Exercise

49

(2)

pp. 349–356

Full Text UEA Repository

(Article)

(Published)


Tang, J. C., Dutton, J. J., Piec, I., Green, D., Fisher, E., Washbourne, C. J., Fraser, W. D.

(2016)

LC–MS/MS application for urine free pyridinoline and free deoxypyridinoline: Urine markers of collagen and bone degradation,

in Clinical Mass Spectrometry

1

pp. 11–18

Full Text UEA Repository

(Article)

(Published)


Piec, I., Chipchase, A., Nicholls, H., Tang, J., Washbourne, C., Fraser, W.

(2016)

FGF23 and Vitamin D Metabolism in Chronic Kidney Disease,

(Poster)

(Published)


Piec, I., Washbourne, C., Tang, J., Fisher, E., Greeves, J., Jackson, S., Fraser, W. D.

(2016)

How accurate is your sclerostin measurement?: Comparison between three commercially available sclerostin ELISA kits,

in Calcified Tissue International

98

(6)

pp. 546-555

Full Text UEA Repository

(Article)

(Published)


He, C., Fraser, W., Tang, J., Brown, K., Renwick, S., Rudland-Thomas, J., Teah, J., Tanqueray, E., Gleeson, M.

(2016)

The effect of 14 weeks of vitamin D3 supplementation on antimicrobial peptides and proteins in athletes,

in Journal of Sports Sciences

34

(1)

pp. 67-74

Full Text UEA Repository

(Article)

(Published)


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Professional Activities

Health and Care Professions Council – Biomedical Scientist  BS43837