Career History

Professional Qualifications and professional memberships 

BMedSci (Hons) – University of Nottingham 1974

BMBS - University of Nottingham 1976

Doctor of Medicine - University of Nottingham 1989

Fellow of the Royal College of Physicians - 1992

Research interests 

  • Cerebrovascular Disease
  • Hypertension and Cardiovascular Risk
  • Cardiovascular Physiology / Physiological Changes with Ageing
  • Cardiovascular Causes of Syncope (Falls)

Career summary 

Following various general medical training posts I was appointed British Heart Foundation Research Fellow at the University of Birmingham where the research for my MD thesis was undertaken into aspects of the relationship between alcohol consumption and blood pressure. In 1985 I was appointed Lecturer in Medicine at the University of Newcastle Upon Tyne, moving in 1989 to the University of Leicester as Senior Lecturer in Medicine for the Elderly. In 1993 I was appointed Chair in Medicine for the Elderly at the University of Leicester, moving to the University of East Anglia in October 2006 as the Foundation Chair in Ageing & Stroke Medicine.

All Publications

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Adekunle-Olarinde, I. R., McCall, S. J., Barlas, R. S., Wood, A. D., Clark, A. B., Bettencourt-Silva, J. H., Metcalf, A. K., Bowles, K. M., Soiza, R. L., Potter, J. F., Myint, P. K.

(2017)

Addition of sodium criterion to SOAR stroke score,

in Acta Neurologica Scandinavica

135

(5)

pp. 553–559

Full Text UEA Repository

(Article)

(Published)


Myint, P. K., Bachmann, M. O., Loke, Y. K., Musgrave, S. D., Price, G. M., Hale, R., Metcalf, A. K., Turner, D. A., Day, D. J., Warburton, E. A., Potter, J. F.

(2017)

Important factors in predicting mortality outcome from stroke: findings from the Anglia Stroke Clinical Network Evaluation Study,

in Age and Ageing

46

(1)

pp. 83-90

Full Text UEA Repository

(Article)

(Published)


Woodhouse, L. J., Manning, L., Potter, J. F., Berge, E., Sprigg, N., Wardlaw, J., Lees, K. R., Bath, P. M., Robinson, T. G.

(2017)

Continuing or Temporarily Stopping Prestroke Antihypertensive Medication in Acute Stroke: An Individual Patient Data Meta-Analysis,

in Hypertension

69

(5)

pp. 933-941

Full Text UEA Repository

(Article)

(Published)


Quinn, T. J., Taylor-Rowan, M., Coyte, A., Clark, A. B., Musgrave, S. D., Metcalf, A. K., Day, D. J., Bachmann, M. O., Warburton, E. A., Potter, J. F., Myint, P. K.

(2017)

Pre-Stroke Modified Rankin Scale: Evaluation of Validity, Prognostic Accuracy, and Association with Treatment,

in Frontiers in Neurology

8

article no. 275

Full Text UEA Repository

(Article)

(Published)


Hooper, L., Bunn, D., Downing, A., Jimoh, F., Groves, J., Free, C., Cowap, V., Potter, J., Hunter, P., Shepstone, L.

(2016)

Which frail older people are dehydrated? The UK DRIE study,

in The Journal of Gerontology: Medical Sciences

71

(10)

pp. 1341-1347

Full Text UEA Repository

(Article)

(Published)


Abdul-Rahim, A. H., Quinn, T. J., Alder, S., Clark, A. B., Musgrave, S. D., Langhorne, P., Potter, J. F., Myint, P. K.

(2016)

Derivation and validation of a novel prognostic scale (modified–stroke subtype, Oxfordshire Community Stroke Project classification, age, and prestroke modified Rankin) to predict early mortality in acute stroke,

in Stroke

47

(1)

pp. 74-79

Full Text UEA Repository

(Article)

(Published)


Abdelhamid, A., Bunn, D. K., Copley, M., Cowap, V., Dickinson, A., Gray, L., Howe, A., Killett, A., Lee, J., Li, F., Poland, F., Potter, J. F., Richardson, K., Smithard, D., Fox, G., Hooper, L.

(2016)

Effectiveness of interventions to directly support food and drink intake in people with dementia: systematic review and meta-analysis,

in BMC Geriatrics

16

article no. 26

Full Text UEA Repository

(Article)

(Published)


Hooper, L., Bunn, D. K., Abdelhamid, A., Gillings, R., Jennings, A., Maas, K., Millar, S., Twomlow, E., Hunter, P. R., Shepstone, L., Potter, J. F., Fairweather-Tait, S. J.

(2016)

Water-loss (intracellular) dehydration assessed using urinary tests, how well do they work? Diagnostic accuracy in older people,

in American Journal of Clinical Nutrition

104

(1)

pp. 121-131

Full Text UEA Repository

(Article)

(Published)


Bunn, D., Abdelhamid, A., Copley, M., Cowap, V., Dickinson, A., Howe, A., Killett, A., Poland, F., Potter, J., Richardson, K., Smithard, D., Fox, C., Hooper, L.

(2016)

Effectiveness of interventions to indirectly support food and drink intake in people with dementia: Eating and Drinking Well IN dementiA (EDWINA) systematic review,

in BMC Geriatrics

16

article no. 89

Full Text UEA Repository

(Article)

(Published)


Barlas, R. S., Honney, K., Loke, Y. K., McCall, S. J., Bettencourt-Silva, J. H., Clark, A. B., Bowles, K. M., Metcalfe, A. K., Mamas, M. A., Potter, J. F., Myint, P. K.

(2016)

Impact of hemoglobin levels and anemia on mortality in acute stroke: analysis of UK regional registry data, systematic review and meta-analysis,

in Journal of the American Heart Association

5

(8)

article no. e003019

Full Text UEA Repository

(Article)

(Published)


Katsogridakis, E., Simpson, D. M., Bush, G., Fan, L., Birch, A. A., Allen, R., Potter, J. F., Panerai, R. B.

(2016)

Revisiting the frequency domain: the multiple and partial coherence of cerebral blood flow velocity in the assessment of dynamic cerebral autoregulation,

in Physiological Measurement

37

article no. 1056

Full Text UEA Repository

(Article)

(Published)


Myint, P. K., Kidd, A. C., Kwok, C. S., Musgrave, S. D., Redmayne, O., Metcalfe, A. K., Ngeh, J., Nicolson, A., Owusu-Agyei, P., Shekhar, R., Walsh, K., Day, D. J., Warburton, E. A., Bachmann, M. O., Potter, J. F.

(2016)

Time to Computerized Tomography Scan, Age, and Mortality in Acute Stroke,

in Journal of Stroke & Cerebrovascular Diseases

25

(12)

pp. 3005–3012

Full Text UEA Repository

(Article)

(Published)


Wood, A. D., Gollop, N. D., Bettencourt-Silva, J. H., Clark, A. B., Metcalf, A. K., Bowles, K. M., Flather, M. D., Potter, J. F., Myint, P. K.

(2016)

A 6-point TACS score predicts in-hospital mortality following total anterior circulation stroke,

in Journal of Clinical Neurology

12

(4)

pp. 407-413

Full Text UEA Repository

(Article)

(Published)


Fletcher, B. R., Hinton, L., Bray, E. P., Hayen, A., Hobbs, F. R., Mant, J., Potter, J. F., McManus, R. J.

(2016)

Self-monitoring blood pressure in patients with hypertension: an internet-based survey of UK GPs,

in British Journal of General Practice

66

(652)

pp. e831-e837

Full Text UEA Repository

(Article)

(Published)


Sabra, A., Stanford, S. N., Storton, S., Lawrence, M., D’Silva, L., Morris, R. H. K., Evans, V., Wani, M., Potter, J. F., Evans, P. A.

(2016)

Assessment of platelet function in patients with stroke using multiple electrode platelet aggregometry: a prospective observational study,

in BMC Neurology

16

article no. 254

Full Text UEA Repository

(Article)

(Published)


Mannu, G. S., Macartney, A., Lambert, J. R. A., Bettencourt-silva, J. H., Lawn, M., Lyall, H., Metcalf, A. K., Potter, J. F., Wood, J., Clark, A., Baglin, T., Myint, P. K., Bowles, K. M.

(2015)

The clinical utility of Multiplate analyser measurement in platelet function testing following stroke and transient ischaemic attack,

in European Journal of Haematology

94

(2)

pp. 138–144

Full Text UEA Repository

(Article)

(Published)


Hooper, L., Abdelhamid, A., Attreed, N. J., Campbell, W. W., Channell, A. M., Chassagne, P., Culp, K. R., Fletcher, S. J., Fortes, M. B., Fuller, N., Gaspar, P. M., Gilbert, D. J., Heathcote, A. C., Kafri, M., Kajii, F., Lindner, G., Mack, G. W., Mentes, J. C., Merlani, P., Needham, R., Olde Rikkert, M. G., Perren, A., Powers, J., Ranson, S., Ritz, P., Rowat, A. M., Sjostrand, F., Smith, A. C., Stookey, J. J., Stotts, N. A., Thomas, D. R., Vivanti, A., Wakefield, B. J., Waldreus, N., Walsh, N. P., Ward, S., Potter, J. F., Hunter, P.

(2015)

Clinical and physical signs for identification of impending and current water-loss dehydration in older people,

in Cochrane Database of Systematic Reviews

article no. CD009647

Full Text UEA Repository

(Article)

(Published)


McCall, S. J., Musgrave, S. D., Potter, J., Hale, R., Clark, A. B., Mamas, M. A., Metcalfe, A. K., Day, D. J., Warburton, E. A., Bachmann, M. A., Myint, P. K.

(2015)

The shock index predicts acute mortality outcomes in stroke,

in International Journal of Cardiology

182

pp. 523-527

Full Text UEA Repository

(Article)

(Published)


Manning, L. S., Mistri, A. K., Potter, J., Rothwell, P. M., Robinson, T. G.

(2015)

Short-term blood pressure variability in acute stroke: a post hoc analysis of the CHHIPS and COSSACS trial,

in Stroke

46

(6)

pp. 1518-1524

Full Text UEA Repository

(Article)

(Published)


Kwok, C. S., Clark, A. B., Musgrave, S. D., Potter, J. F., Dalton, G., Day, D. J., George, A., Metcalf, A. K., Ngeh, J., Nicolson, A., Owusu-agyei, P., Shekhar, R., Walsh, K., Warburton, E. A., Bachmann, M. O., Myint, P. K.

(2015)

The SOAR stroke score predicts hospital length of stay in acute stroke: an external validation study,

in International Journal of Clinical Practice

69

(6)

pp. 659-665

Full Text UEA Repository

(Article)

(Published)


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Key Research Interests

STROKE 

  • Principle Investigator in two large multi-centre UK based trials of the management of blood pressure in acute stroke, the Control of Hypertension and Hypotension Immediately Post Stroke (CHIPPS) trial, pilot data published in Lancet Neurology (2009). The Continue Or Stop post Stroke Anti-hypertensive Collaborative Study (COSSACS), run in conjunction with CHHIPS is on going and has been adopted by the Stroke Research Network.
  • Acute Stroke studies has centred on assessing the mechanisms underlying the changes in blood pressure and cerebral blood flow haemodynamics during the acute stroke period. 
  • I Chair the International Trial Steering Committees’ of the Asymptomatic Carotid Surgery Trial-1 and 2.
  • I am member of the Royal College of Physicians UK Audit Committee on Carotid Endartectomy and was a member of the NICE Guidelines Committee for Acute Stroke that reported in 2008.

HYPERTENSION

  • Member of the British Hypertension Society (BHS) and Joint British Society’s Cardiovascular Risk Guidelines Committee responsible for assessing and developing guidelines particularly with regard to the management of Hypertension and Cardiovascular Risk Factors in older age and in relation to stroke.
  • I have a long standing interest in blood pressure measurement and Chair the BHS Blood Pressure Measurement Committee. Current research interests revolve around the effects of diet on cardiovascular risk factors and self measurement of blood pressure.
  • CARDIOVASCULAR PHYSIOLOGY OF AGEING. 
  • With other collaborators from the University’s of Leicester and Southampton we have developed various non-invasive methods of assessing cerebral blood flow and its control mechanisms using Transcranial Doppler, currently funded by the EPSRC. 
  • I also have a particular interest in the measurement of other physiological variables such as dynamic cerebral autoregulation, cardiac baroreceptor sensitivity and pulse wave velocity and these are currently being employed in various on going studies.

CARDIOVASCULAR PHYSIOLOGY OF AGEING;

  • With other collaborators from the University’s of Leicester and Southampton we have developed various non-invasive methods of assessing cerebral blood flow and its control mechanisms using Transcranial Doppler, currently funded by the EPSRC. 
  • I also have a particular interest in the measurement of other physiological variables such as dynamic cerebral autoregulation, cardiac baroreceptor sensitivity and pulse wave velocity and these are currently being employed in various on going studies.

CARDIOVASCULAR SYNCOPE.

Our group has been studying the under lying hemodynamic changes with various types of syncope associated with ageing. These research interests are complimentary to my clinical commitments as I run a cardiovascular syncope clinic at the Norfolk and Norwich University Hospital.

Selected publications

Potter JF, Robinson TG, Ford GA, Mistri A, James M, Chernova J, Jagger C. Controlling hypertension and hypotension immediately post-stroke (CHHIPS): a randomised, placebo-controlled, double-blind pilot trial. Lancet Neurology 2009;8:48-56.

Halliday A, Lees T, Kamugasha D, Grant R, Hoffman A, Rothwell P, Potter JF, Horrocks M, Naylor R, Rudd T. Long waiting times for Carotid Endartectomy in the UK. BMJ 2009 (in press).

MacManus R, Glasziou P, Bray E, Hayen A, Mant J, Mant D, Padfield P, Potter JF. Blood Pressure Self Monitoring. BMJ 2009; 338:38-42.

Smith, SM. 1; Potter JF. 2; Samani NJ. 1; Sammons EL; Rathbone WE, Bentley S, Panerai RB. Influence of non-invasive measurements of arterial blood pressure in frequency and time-domain estimates of cardiac baroreflex sensitivity. Journal of Hypertension. 2008; 26:76-82.

Eveson D, Robinson TG, Potter JF. Lisinopril for the treatment of hypertension within the first 24 hours of acute ischaemic stroke and follow-up. American Journal of Hypertension 2007; 20:270-277.

Sammons E, Smith SM, Bentley S, Samani N, Potter JF, Panerai RB. Influence of non-invasive peripheral arterial blood pressure measurements on assessment of dynamic cerebral autoregulation. Journal of Applied Physiology 2007; 103:369-375.

Brittain K, Perry S, Shaw C, Matthew R, Jagger C, Potter JF. Isolated urinary, faecal and double incontinence: Prevalence and degree of soiling in Stroke Survivors. Journal of the American Geriatric Society 2006; 54:1915-1919.

Panerai RB. Eames PJ. Potter JF. Multiple coherence of cerebral blood flow velocity in humans. American Journal of Physiology - Heart & Circulatory Physiology 2006 291(1):H251-9.

Eveson D, Robinson TG, Shah NS, Paul SK, Panerai RB, Potter JF. Abnormalities in cardiac baroreceptor sensitivity in acute stroke patients are related to aortic stiffness. Clinical Science 2005; 108:441-447.

Williams B, Poulter NR, Brown MJ, Davis M, McInnes GT, Potter JF, Sever PS, Thom SM. British Hypertension Society guidelines for hypertension management 2004 (BHS-IV): summary. BMJ 2004; 328:634-640.

Teaching Interests

Undergraduate – I am lead for Second Year undergraduate teaching and lecture on numerous undergraduate courses.

Postgraduate – I am Lead for the Stroke & Rehabilitation Group of the Health and Social Sciences research Institute and principal supervisor for both MD and PhD students at UEA and other universities. I lecture on the UEA MSc course in Stroke Medicine. I am also on the Examination Board for a Diploma of Geriatric Medicine and act as external examiner at undergraduate level for several universities including University of Nottingham and University of Newcastle Upon Tyne.

External Activities and Indicators of Esteem

  • 2001 - presentMember of the Editorial Board of The British Journal of Diabetes and Vascular Disease.
  • 2002 - presentMember Joint British Cardiovascular Guidelines Committee
  • 2002 - presentChairman of the British Hypertension Society’s Blood Pressure Measurement Committee
  • 2002 - presentStroke Association Consultee on NICE Guidelines
  • 2003 - presentMember of the MHRA Working Party on BP Measurement
  • 2004 - presentChairman of the British Geriatric Society Academic and Research Committee
  • 2004 - presentMember of the British Geriatric Society UK Management Committee
  • 2005 - presentBritish Heart Foundation Clinical Guidelines Contributor
  • 2005 - presentMember Royal College of Physicians Carotid Endartectomy Audit Committee
  • 2005 - presentMember of Department of Health Stroke Strategy Group: Prevention and Public Awareness Project Group
  • 2006 - presentMember of Royal College of Physicians NCC-CC/NICE Guideline Development Group on Acute Stroke and TIA Guidelines
  • 2006 - presentDeputy Editor Age & Ageing
  • 2007 - presentChair Department of Health Expert Reference Panel - Acute Stroke
  • 2008 - presentMember of Health Technology Panel Assessment Panel
  • 2008 - presentLead for Stroke for the Ageing Comprehensive Local Research Network
  • International
  • 1995 - present:Hypertension in the Very Elderly Trial (HYVET) Steering Committee Member and Chair
  • 1999 - presentChairman of the Steering Committee for the MRC Asymptomatic Carotid Surgery Trial (ACST).
  • 2006 - presentChairman of the Steering Committee for the HTA funded Asymptomatic Carotid Surgery 2 Trial (ACST2).
  • 2006 - presentMember of Editorial Board Journal of Hypertension