Biography

I have been involved in Magnetic Resonance Imaging research since 1978 and as a PhD student was a member of the research group at Aberdeen University that developed “spin warp imaging”, one of the key MRI technologies that is still the basis of most MRI methods. Since then, I have worked at a variety of Universities, both in the UK and the US on both fundamental MRI physics and engineering and the application of MRI in the clinic. Before moving back to the UK to take up my current position at UEA, I led the brain tumour imaging research group at New York University.

Career History

  • 1981-1983: Research Assistant in NMR Imaging. Department of BioMedical Physics and BioEngineering, University of Aberdeen, Aberdeen.
  • 1983-1988: Senior Physicist and Honorary Lecturer in NMR Imaging. Department of Clinical Neurology, Institute of Neurology, Queen Square, London.
  • 1988-1994: Assistant Professor of Radiology, Department of Radiology, College of Physicians and Surgeons of Columbia University, New York, New York.
  • 1994-2001: Assistant Professor of Radiology, Department of Radiology, New York University School of Medicine, New York, New York.
  • 2001-2005: Associate Professor of Radiology, Department of Radiology, New York University School of Medicine, New York, New York.
  • 2005-2012: Associate Professor of Radiology and Physiology and Neuroscience, Department of Radiology, New York University School of Medicine, New York, New York.
  • 2012-present: Adjunct Associate Professor of Radiology, Department of Radiology, New York University School of Medicine, New York, New York.
  • 2012-present: Professor of Clinical MRI Physics, Norwich Medical School, University of East Anglia, Norwich.

Academic Background

  • 1974-1977: Pembroke College, Cambridge. BA Natural Sciences (Physics and Theoretical Physics).
  • 1977: Department of Biomedical Physics and Bioengineering, Aberdeen University. MSc Medical Physics.
  • 1978-1981: Department of Biomedical Physics and Bioengineering, Aberdeen University. PhD Medical Physics.

All Publications

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Gilani, N., Malcolm, P., Johnson, G.

(2017)

A model describing diffusion in prostate cancer,

in Magnetic Resonance in Medicine

78

(1)

pp. 316–326

Full Text UEA Repository

(Article)

(Published)


MacKay, J. W., Murray, P. J., Kasmai, B., Johnson, G., Donell, S. T., Toms, A. P.

(2017)

Subchondral bone in osteoarthritis: Association between MRI texture analysis and histomorphometry,

in Osteoarthritis and Cartilage

25

(5)

pp. 700–707

Full Text UEA Repository

(Article)

(Published)


Godley, K., Syer, T., Toms, A., Smith, T., Johnson, G., Cameron, D., Malcolm, P.

(2017)

Accuracy of high b-value diffusion-weighted MRI for prostate cancer detection: a meta-analysis,

in Acta Radiologica

Full Text UEA Repository

(Article)

(E-pub ahead of print)


Gilani, N., Malcolm, P., Johnson, G.

(2017)

A monte carlo study of restricted diffusion: Implications for diffusion MRI of prostate cancer,

in Magnetic Resonance in Medicine

77

(4)

pp. 1671–1677

Full Text UEA Repository

(Article)

(Published)


Gilani, N., Malcolm, P. N., Johnson, G.

(2016)

Parameter Estimation Error Dependency on the Acquisition Protocol in Diffusion Kurtosis Imaging,

in Applied Magnetic Resonance

47

(11)

pp. 1229–1238

Full Text UEA Repository

(Article)

(Published)


MacKay, J. W., Murray, P. J., Kasmai, B., Johnson, G., Donell, S. T., Toms, A. P.

(2016)

MRI texture analysis of subchondral bone at the tibial plateau,

in European Radiology

26

(9)

pp. 3034–3045

Full Text UEA Repository

(Article)

(Published)


Cawley, P., Few, K., Greenwood, R., Malcolm, P., Johnson, G., Lally, P., Thayyil, S., Clarke, P.

(2016)

Does magnetic resonance brain scanning at 3.0 Tesla pose a hyperthermic challenge to term neonates?,

in Journal of Pediatrics

175

pp. 228-230.e1

Full Text UEA Repository

(Article)

(Published)


MacKay, J. W., Murray, P. J., Low, S. B. L., Kasmai, B., Johnson, G., Donell, S. T., Toms, A. P.

(2016)

Quantitative analysis of tibial subchondral bone: Texture analysis outperforms conventional trabecular microarchitecture analysis,

in Journal of Magnetic Resonance Imaging

43

(5)

pp. 1159–1170

Full Text UEA Repository

(Article)

(Published)


Lewis, M., Ebreo, D., Malcolm, P. N., Greenwood, R., Patel, A. D., Kasmai, B., Johnson, G., Toms, A. P.

(2016)

Pharmacokinetic modeling of multislice dynamic contrast-enhanced MRI in normal-healing radial fractures: A pilot study,

in Journal of Magnetic Resonance Imaging

43

(3)

pp. 611-619

Full Text UEA Repository

(Article)

(Published)


Abdulla, S., Saada, J., Johnson, G., Jefferies, S., Ajithkumar, T.

(2015)

Tumour progression or pseudoprogression?: A review of post-treatment radiological appearances of glioblastoma,

in Clinical Radiology

70

(11)

pp. 1299-1312

Full Text UEA Repository

(Article)

(Published)


Gilani, N., Rosenkrantz, A. B., Malcolm, P., Johnson, G.

(2015)

Minimisation of errors in biexponential T2 measurements of the prostate,

in Journal of Magnetic Resonance Imaging

42

(4)

pp. 1072-1077

Full Text UEA Repository

(Article)

(Published)


Ibrahim, T., Few, K., Greenwood, R., Smith, C., Malcolm, P., Johnson, G., Lally, P., Thayyil, S., Clarke, P.

(2015)

'Feed and wrap' or sedate and immobilise for neonatal brain MRI?,

in Archives of disease in childhood. Fetal and neonatal edition

100

(5)

Full Text

(Letter)

(Published)


Patil, V., Johnson, G.

(2013)

DeltaR2 (*) gadolinium-diethylenetriaminepentacetic acid relaxivity in venous blood,

in Magnetic Resonance in Medicine

69

(4)

pp. 1104-1108

Full Text UEA Repository

(Article)

(Published)


Patil, V., Jensen, J. H., Johnson, G.

(2013)

Intravascular contrast agent T2* relaxivity in brain tissue,

in NMR in Biomedicine

26

(4)

pp. 392-399

Full Text UEA Repository

(Article)

(Published)


Trampel, R., Johnson, G.

(2013)

Analytical derivation of the b matrix of a time-efficient isotropic diffusion weighting gradient waveform,

in Medical Physics

40

(3)

article no. 032301

Full Text UEA Repository

(Article)

(Published)


Rosenkrantz, A. B., Sigmund, E. E., Johnson, G., Babb, J. S., Mussi, T. C., Melamed, J., Taneja, S. S., Lee, V. S., Jensen, J. H.

(2012)

Prostate cancer: feasibility and preliminary experience of a diffusional kurtosis model for detection and assessment of aggressiveness of peripheral zone cancer,

in Radiology

264

(1)

pp. 126-135

Full Text UEA Repository

(Article)

(Published)


Fatterpekar, G. M., Galheigo, D., Narayana, A., Johnson, G., Knopp, E.

(2012)

Treatment-related change versus tumor recurrence in high-grade gliomas: a diagnostic conundrum--use of dynamic susceptibility contrast-enhanced (DSC) perfusion MRI,

in American Journal of Roentgenology

198

(1)

pp. 19-26

Full Text UEA Repository

(Article)

(Published)


Patil, V., Johnson, G.

(2011)

An improved model for describing the contrast bolus in perfusion MRI,

in Medical Physics

38

(12)

pp. 6380

Full Text UEA Repository

(Article)

(Published)


Cazettes, F., Tsui, W. H., Johnson, G., Steen, R. G., Convit, A.

(2011)

Systematic differences between lean and obese adolescents in brain spin-lattice relaxation time: a quantitative study,

in American Journal of Neuroradiology

32

(11)

pp. 2037-2042

Full Text UEA Repository

(Article)

(Published)


Caseiras, G. B., Chheang, S., Babb, J., Rees, J. H., Pecerrelli, N., Tozer, D. J., Benton, C., Zagzag, D., Johnson, G., Waldman, A. D., Jager, H. R., Law, M.

(2010)

Relative cerebral blood volume measurements of low-grade gliomas predict patient outcome in a multi-institution setting,

in European Journal of Radiology

73

(2)

pp. 215-220

Full Text UEA Repository

(Article)

(Published)


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Key Research Interests

MRI is unsurpassed in demonstrating the presence of anatomical abnormalities throughout the body. However, it is often difficult to distinguish between different types of lesion from appearance alone. For example, the MRI appearance of some benign lesions can mimic the appearance of malignant tumours potentially leading to incorrect identification and inappropriate treatment. My main research interest is therefore in developing quantitative techniques that allow the resolution of these diagnostic problems, particularly in relation to cancer.

Research Keywords: MRI, Cancer

Research Topics for PGR Supervision: MRI

Selected Publications:

W. A. Edelstein, J. M. S. Hutchison, G. Johnson and T. W. Redpath, Spin warp imaging and applications to whole body imaging. Phys. Med. Biol. 25, 751-756 (1980).

  • G. Johnson, J. M. S. Hutchison, T. W. Redpath and L. M. Eastwood, Improvements in performance time for simultaneous three-dimensional NMR imaging. J. Magn. Reson. 54, 374-384 (1983).
  • G. Johnson and J. M. S. Hutchison, The limitations of NMR recalled-echo imaging techniques. J. Magn. Reson. 63, 14-30 (1985).
  • D. H. Miller, G. Johnson, W. I. McDonald, D. MacManus, E. P. G. H. du Boulay, B. E. Kendall and I. F. Moseley, Detection of optic nerve lesions in optic neuritis with magnetic resonance imaging. Lancet 1, 1490-1491 (1986).
  • G. Johnson, S. G. Wetzel, S. Cha, J. M. Babb, P. S. Tofts. Measuring blood volume and vascular transfer constant from dynamic, T2*-weighted contrast-enhanced MRI. Magn. Reson. Med. 51, 961-968 (2004).
  • M. Law, S. Oh, J. Babb, E. Wang, M. Inglese, D. Zagzag, E. A. Knopp, G. Johnson. Low-grade gliomas: Dynamic susceptibility-weighted contrast-enhanced perfusion MR imaging—prediction of patient clinical response. Radiology 238, 658-667 (2006).
  • R. Trampel, J.H. Jensen, R. Lee, I. Kamenestkiy, G. McGuinness, G. Johnson, Pulmonary diffusional kurtosis imaging using hyperpolarized 3-helium. Magn. Reson. Med. 56, 733-737 (2006).
  • M. Law, J. Brodsky, J. Babb, M. Rosenblum, D.C. Miller, D. Zagzag, M.L. Gruber, G. Johnson. High cerebral blood volume in human gliomas predicts deletion of chromosome 1p: Preliminary results of molecular studies in gliomas with elevated perfusion. J. Magn. Reson. Im. 25, 1113-1119 (2007).
  • M. Inglese, G. Madelin, N. Oesingmann, J.S. Babb, W. Wu, B. Stoeckel, J. Herbert, G. Johnson. Brain tissue sodium concentration in multiple sclerosis: a sodium imaging study at 3 tesla. Brain 133, 847-857 (2010).
  • V. Patial, G. Johnson. Relaxivity in tissue.

External Activities and Indicators of Esteem

  • ISMRM annual meeting program committee member 2005-2007
  • Member of NIH study sections 2005-present
  • Reviewer for multiple academic journals 1984-present