All Publications

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Cooper, C. S., Clark, J., Brewer, D. S., Edwards, D. R.

(2016)

Prostate Single Nucleotide Polymorphism Provides a Crucial Clue to Cancer Aggression in Active Surveillance Patients

Full Text

(Editorial)


Pal, R. P., Kockelbergh, R. C., Pringle, J. H., Cresswell, L., Hew, R., Dormer, J. P., Cooper, C., Mellon, J. K., Barwell, J. G., Hollox, E. J.

(2016)

Immunocytochemical detection of ERG expression in exfoliated urinary cells identifies with high specificity patients with prostate cancer

Full Text UEA Repository

(Article)


White, C., Alshaker, H., Cooper, C., Winkler, M., Pchejetski, D.

(2016)

The emerging role of FTY720 (Fingolimod) in cancer treatment

Full Text

(Literature review)


Behjati, S., Gundem, G., Wedge, D. C., Roberts, N. D., Tarpey, P. S., Cooke, S. L., Van Loo, P., Alexandrov, L. B., Ramakrishna, M., Davies, H., Nik-Zainal, S., Hardy, C., Latimer, C., Raine, K. M., Stebbings, L., Menzies, A., Jones, D., Shepherd, R., Butler, A. P., Teague, J. W., Jorgensen, M., Khatri, B., Pillay, N., Shlien, A., Futreal, P. A., Badie, C., Cooper, C. S., Eeles, R. A., Easton, D., Foster, C., Neal, D. E., Brewer, D. S., Hamdy, F., Lu, Y., Lynch, A. G., Massi, C. E., Ng, A., Whitaker, H. C., Yu, Y., Zhang, H., Bancroft, E., Berney, D., Camacho, N., Corbishley, C., Dadaev, T., Dennis, N., Dudderidge, T., Edwards, S., Fisher, C., Ghori, J., Gnanapragasam, V. J., Greenman, C., Hawkins, S., Hazell, S., Howat, W., Karaszi, K., Kay, J., Kote-Jarai, Z., Kremeyer, B., Kumar, P., Lambert, A., Leongamornlert, D., Livni, N., Luxton, H., Matthews, L., Mayer, E., Merson, S., Nicol, D., Ogden, C., O’Meara, S., Pelvender, G., Shah, N. C., Tavare, S., Thomas, S., Thompson, A., Verrill, C., Warren, A., Zamora, J., McDermott, U., Bova, G. S., Richardson, A. L., Flanagan, A. M., Stratton, M. R., Campbell, P. J.

(2016)

Mutational signatures of ionizing radiation in second malignancies

Full Text UEA Repository

(Article)


Alshaker, H., Wang, Q., Kawano, Y., Arafat, T., Böhler, T., Winkler, M., Cooper, C., Pchejetski, D.

(2016)

Everolimus (RAD001) sensitizes prostate cancer cells to docetaxel by down-regulation of HIF-1α and sphingosine kinase 1

Full Text UEA Repository

(Article)


Alshaker, H., Wang, Q., Frampton, A. E., Krell, J., Waxman, J., Winkler, M., Stebbing, J., Cooper, C., Yaguee, E., Pchejetski, D.

(2015)

Sphingosine kinase 1 contributes to leptin-induced STAT3 phosphorylation through IL-6/gp130 transactivation in oestrogen receptor-negative breast cancer

Full Text UEA Repository

(Article)


Cooper, C., Eeles, R. A., Wedge, D. C., Van loo, P., Gundem, G., Alexandrov, L., Kreymer, B., Butler, A., Lynch, A., Edwards, S. E., Camacho, N., Massie, C. E., Kote-Jarai, Z., Dennis, N., Merson, S., Leongamornlert, D. A., Zamora, J., Kay, J., Luxton, H. J., Corbishley, C., Thomas, S., Nik-zainal, S., O'Meara, S., Matthews, L., Clark, J., Hurst, R., Mithen (IFR), R., Bristow (Ontario Cancer Inst. CA), R., Boutros, P. C., Fraser, M., Cooke, S., Raine, K., Jones, D., Menzies, A., Stebbings, L., Hinton, J., Teague, J., Mclaren, S., Mudie, L., Hardy, C., Anderson, E., Joseph, O., Goody, V., Robinson, B., Maddison, M., Gamble, S., Greenman, C., Berney, D., Hazell, S., Livni, N., Fisher, C., Ogden, C., Kumar, P., Thompson, A., Woodhouse, C. J., Nicol, D., Mayer, E., Dudderidge, T., Shah, N., Gnanapragasam (Cambridge), V., Voet, T., Campbell, P., Futreal, P. A., Easton, D. F., Warren, A. Y., Foster, C. S., Stratton, M. R., Whitaker, H. C., Mcdermott, U., Brewer, D., Neal, D. E.

(2015)

Analysis of the genetic phylogeny of multifocal prostate cancer identifies multiple independent clonal expansions in neoplastic and morphologically normal prostate tissue

Full Text

(Letter)


Manson-Bahr, D., Ball, R., Gundem, G., Mills, R., Rochester, M., Goody, V., O'Meara, S., Flather, M., Keeling, M., Yazbek Hanna, M., Hurst, R., Curley, H., Clark, J., Brewer, D., Mcdermott, U., Cooper, C.

(2015)

Mutation Detection in Formalin-Fixed Prostate Cancer Biopsies Taken at the Time of Diagnosis Using Next Generation DNA Sequencing

Full Text UEA Repository

(Article)


Gundem, G., Van loo, P., Kremeyer, B., Alexandrov, L., Tubio, J. M. C., Papaemmanuil, E., Brewer, D., Kallio, H., Högnäs, H., Annala, M., Kivinummi, K., Goody, V., Latimer, C., O'Meara, S., Dawson, K., Isaacs, W., Emmert-Buck, M. R., Nykter, M., Foster, C. S., Kote-Jarai, Z., Easton, D. F., Whitaker, H. C., Neal, D. E., Cooper, C., Eeles, R. A., Visakorpi, T., Campbell, P., Mcdermott, U., Wedge, D. C., Bova, G. S.

(2015)

The Evolutionary History of Lethal Metastatic Prostate Cancer

Full Text

(Letter)


Massie, C. E., Spiteri, I., Ross-Adams, H., Luxton, H. J., Kay, J., Whitaker, H. C., Dunning, M. J., Lamb, A. D., Ramos-Montoya, A., Brewer, D., Cooper, C., Eeles, R. A., Warren, A. Y., Tavaré, S., Neal, D. E., Lynch, A. G.

(2015)

HES5 silencing is an early and recurrent change in prostate tumourigenesis

Full Text UEA Repository

(Article)


Ju, Y. S., Tubio, J. M., Mifsud, W., Fu, B., Davies, H. R., Ramakrishna, M., Li, Y., Yates, L., Gundem, G., Tarpey, P. S., Behjati, S., Papaemmanuil, E., Martin, S., Fullam, A., Gerstung, M., Nangalia, J., Green, A. R., Caldas, C., Borg, Å., Tutt, A., Lee, M. T. M., Van't Veer, L. J., Tan, B. K., Aparicio, S., Span, P. N., Martens, J. W., Knappskog, S., Vincent-salomon, A., Børresen-dale, A., Eyfjörd, J. E., Flanagan, A. M., Foster, C., Neal, D. E., Cooper, C., Eeles, R., Lakhani, S. R., Desmedt, C., Thomas, G., Richardson, A. L., Purdie, C. A., Thompson, A. M., Mcdermott, U., Yang, F., Nik-zainal, S., Campbell, P. J., Stratton, M. R.

(2015)

Frequent somatic transfer of mitochondrial DNA into the nuclear genome of human cancer cells

Full Text UEA Repository

(Article)


Boutros, P. C., Fraser, M., Harding, N. J., De Borja, R., Trudel, D., Lalonde, E., Meng, A., Hennings-yeomans, P. H., Mcpherson, A., Sabelnykova, V. Y., Zia, A., Fox, N. S., Livingstone, J., Shiah, Y., Wang, J., Beck, T. A., Have, C. L., Chong, T., Sam, M., Johns, J., Timms, L., Buchner, N., Wong, A., Watson, J. D., Simmons, T. T., P'ng, C., Zafarana, G., Nguyen, F., Luo, X., Chu, K. C., Prokopec, S. D., Sykes, J., Dal Pra, A., Berlin, A., Brown, A., Chan-seng-yue, M. A., Yousif, F., Denroche, R. E., Chong, L. C., Chen, G. M., Jung, E., Fung, C., Starmans, M. H. W., Chen, H., Govind, S. K., Hawley, J., D'costa, A., Pintilie, M., Waggott, D., Hach, F., Lambin, P., Muthuswamy, L. B., Cooper, C., Eeles, R., Neal, D., Tetu, B., Sahinalp, C., Stein, L. D., Fleshner, N., Shah, S. P., Collins, C. C., Hudson, T. J., Mcpherson, J. D., Van Der Kwast, T., Bristow, R. G.

(2015)

Spatial genomic heterogeneity within localized, multifocal prostate cancer

Full Text UEA Repository

(Article)


Bettencourt-Silva, J. H., Clark, J., Cooper, C. S., Mills, R., Rayward-Smith, V. J., De La Iglesia, B.

(2015)

Building Data-Driven Pathways From Routinely Collected Hospital Data: A Case Study on Prostate Cancer

Full Text UEA Repository

(Article)


Ross-Adams, H., Lamb, A., Dunning, M., Halim, S., Lindberg, J., Massie, C., Egevad, L., Russell, R., Ramos-Montoya, A., Vowler, S., Sharma, N., Kay, J., Whitaker, H., Clark, J., Hurst, R., Gnanapragasam, V., Shah, N., Warren, A., Cooper, C., Lynch, A., Stark, R., Mills, I., Groenberg, H., Neal, D.

(2015)

Integration of copy number and transcriptomics provides risk stratification in prostate cancer: A discovery and validation cohort study

Full Text UEA Repository

(Article)


Merson, S., Yang, Z. H., Brewer, D., Olmos, D., Eichholz, A., McCarthy, F., Fisher, G., Kovacs, G., Berney, D. M., Foster, C. S., Møller, H., Scardino, P., Cuzick, J., Cooper, C. S., Clark, J.

(2014)

Focal amplification of the androgen receptor gene in hormone-naive human prostate cancer

Full Text UEA Repository

(Article)


Tubio, J. M. C., Li, Y., Ju, Y. S., Martincorena, I., Cooke, S. L., Tojo, M., Gundem, G., Pipinikas, C. P., Zamora, J., Raine, K., Menzies, A., Roman-Garcia, P., Fullam, A., Gerstung, M., Shlien, A., Tarpey, P. S., Papaemmanuil, E., Knappskog, S., Van Loo, P., Ramakrishna, M., Davies, H. R., Marshall, J., Wedge, D. C., Teague, J. W., Butler, A. P., Nik-Zainal, S., Alexandrov, L., Behjati, S., Yates, L. R., Bolli, N., Mudie, L., Hardy, C., Martin, S., McLaren, S., O'Meara, S., Anderson, E., Maddison, M., Gamble, S., Foster, C., Warren, A. Y., Whitaker, H., Brewer, D., Eeles, R., Cooper, C., Neal, D., Lynch, A. G., Visakorpi, T., Isaacs, W. B., van't Veer, L., Caldas, C., Desmedt, C., Sotiriou, C., Aparicio, S., Foekens, J. A., Eyfjörd, J. E., Lakhani, S. R., Thomas, G., Myklebost, O., Span, P. N., Børresen-Dale, A., Richardson, A. L., Van de Vijver, M., Vincent-Salomon, A., Van den Eynden, G. G., Flanagan, A. M., Futreal, P. A., Janes, S. M., Bova, G. S., Stratton, M. R., McDermott, U., Campbell, P. J., Genome, Human, Mutagenesis, Insertional, Transduction, Genetic, Translocation, Genetic

(2014)

Mobile DNA in cancer. Extensive transduction of nonrepetitive DNA mediated by L1 retrotransposition in cancer genomes

Full Text UEA Repository

(Article)


Zuo, J., Brewer, D., Arlt, V. M., Cooper, C., Phillips, D. H.

(2014)

Benzo[a]pyrene-induced DNA adducts and gene expression profiles in target and non-target organs for carcinogenesis in mice

Full Text UEA Repository

(Article)


Ju, Y. S., Alexandrov, L. B., Gerstung, M., Martincorena, I., Nik-Zainal, S., Ramakrishna, M., Davies, H. R., Papaemmanuil, E., Gundem, G., Shlien, A., Bolli, N., Behjati, S., Tarpey, P. S., Nangalia, J., Massie, C. E., Butler, A. P., Teague, J. W., Vassiliou, G. S., Green, A. R., Du, M., Unnikrishnan, A., Pimanda, J. E., Teh, B. T., Munshi, N., Greaves, M., Vyas, P., El-Naggar, A. K., Santarius, T., Collins, V. P., Grundy, R., Taylor, J. A., Hayes, D. N., Malkin, D., Foster, C. S., Warren, A. Y., Whitaker, H. C., Brewer, D., Eeles, R., Cooper, C., Neal, D., Visakorpi, T., Isaacs, W. B., Bova, G. S., Flanagan, A. M., Futreal, P. A., Lynch, A. G., Chinnery, P. F., McDermott, U., Stratton, M. R., Campbell, P. J.

(2014)

Origins and functional consequences of somatic mitochondrial DNA mutations in human cancer

Full Text UEA Repository

(Article)


Lalonde, E., Ishkanian, A. S., Sykes, J., Fraser, M., Ross-Adams, H., Erho, N., Dunning, M. J., Halim, S., Lamb, A. D., Moon, N. C., Zafarana, G., Warren, A. Y., Meng, X., Thoms, J., Grzadkowski, M. R., Berlin, A., Have, C. L., Ramnarine, V. R., Yao, C. Q., Malloff, C. A., Cooper, C.

(2014)

Tumour genomic and microenvironmental heterogeneity as integrated predictors for prostate cancer recurrence: a retrospective study

Full Text UEA Repository

(Article)


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