All Publications

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Cooper, C. S., Clark, J., Brewer, D. S., Edwards, D. R.

(2016)

Prostate Single Nucleotide Polymorphism Provides a Crucial Clue to Cancer Aggression in Active Surveillance Patients

in European Urology

69.

pp. 229-30

Full Text

(Editorial)


Pal, R. P., Kockelbergh, R. C., Pringle, J. H., Cresswell, L., Hew, R., Dormer, J. P., Cooper, C., Mellon, J. K., Barwell, J. G., Hollox, E. J.

(2016)

Immunocytochemical detection of ERG expression in exfoliated urinary cells identifies with high specificity patients with prostate cancer

in BJU International

117.

pp. 686-696

Full Text UEA Repository

(Article)


White, C., Alshaker, H., Cooper, C., Winkler, M., Pchejetski, D.

(2016)

The emerging role of FTY720 (Fingolimod) in cancer treatment

in Oncotarget

7.

Full Text UEA Repository

(Article)


Behjati, S., Gundem, G., Wedge, D. C., Roberts, N. D., Tarpey, P. S., Cooke, S. L., Van Loo, P., Alexandrov, L. B., Ramakrishna, M., Davies, H., Nik-Zainal, S., Hardy, C., Latimer, C., Raine, K. M., Stebbings, L., Menzies, A., Jones, D., Shepherd, R., Butler, A. P., Teague, J. W., Jorgensen, M., Khatri, B., Pillay, N., Shlien, A., Futreal, P. A., Badie, C., Cooper, C. S., Eeles, R. A., Easton, D., Foster, C., Neal, D. E., Brewer, D. S., Hamdy, F., Lu, Y., Lynch, A. G., Massi, C. E., Ng, A., Whitaker, H. C., Yu, Y., Zhang, H., Bancroft, E., Berney, D., Camacho, N., Corbishley, C., Dadaev, T., Dennis, N., Dudderidge, T., Edwards, S., Fisher, C., Ghori, J., Gnanapragasam, V. J., Greenman, C., Hawkins, S., Hazell, S., Howat, W., Karaszi, K., Kay, J., Kote-Jarai, Z., Kremeyer, B., Kumar, P., Lambert, A., Leongamornlert, D., Livni, N., Luxton, H., Matthews, L., Mayer, E., Merson, S., Nicol, D., Ogden, C., O’Meara, S., Pelvender, G., Shah, N. C., Tavare, S., Thomas, S., Thompson, A., Verrill, C., Warren, A., Zamora, J., McDermott, U., Bova, G. S., Richardson, A. L., Flanagan, A. M., Stratton, M. R., Campbell, P. J.

(2016)

Mutational signatures of ionizing radiation in second malignancies

in Nature Communications

7.

Full Text UEA Repository

(Article)


Alshaker, H., Wang, Q., Kawano, Y., Arafat, T., Böhler, T., Winkler, M., Cooper, C., Pchejetski, D.

(2016)

Everolimus (RAD001) sensitizes prostate cancer cells to docetaxel by down-regulation of HIF-1α and sphingosine kinase 1

in Oncotarget

Full Text UEA Repository

(Article)


Alshaker, H., Wang, Q., Frampton, A. E., Krell, J., Waxman, J., Winkler, M., Stebbing, J., Cooper, C., Yagüe, E., Pchejetski, D.

(2015)

Sphingosine kinase 1 contributes to leptin-induced STAT3 phosphorylation through IL-6/gp130 transactivation in oestrogen receptor-negative breast cancer

in Breast Cancer Research and Treatment

149.

pp. 59-67

Full Text UEA Repository

(Article)


Cooper, C., Eeles, R. A., Wedge, D. C., Van loo, P., Gundem, G., Alexandrov, L., Kreymer, B., Butler, A., Lynch, A., Edwards, S. E., Camacho, N., Massie, C. E., Kote-Jarai, Z., Dennis, N., Merson, S., Leongamornlert, D. A., Zamora, J., Kay, J., Luxton, H. J., Corbishley, C., Thomas, S., Nik-zainal, S., O'Meara, S., Matthews, L., Clark, J., Hurst, R., Mithen (IFR), R., Bristow (Ontario Cancer Inst. CA), R., Boutros, P. C., Fraser, M., Cooke, S., Raine, K., Jones, D., Menzies, A., Stebbings, L., Hinton, J., Teague, J., Mclaren, S., Mudie, L., Hardy, C., Anderson, E., Joseph, O., Goody, V., Robinson, B., Maddison, M., Gamble, S., Greenman, C., Berney, D., Hazell, S., Livni, N., Fisher, C., Ogden, C., Kumar, P., Thompson, A., Woodhouse, C. J., Nicol, D., Mayer, E., Dudderidge, T., Shah, N., Gnanapragasam (Cambridge), V., Voet, T., Campbell, P., Futreal, P. A., Easton, D. F., Warren, A. Y., Foster, C. S., Stratton, M. R., Whitaker, H. C., Mcdermott, U., Brewer, D., Neal, D. E.

(2015)

Analysis of the genetic phylogeny of multifocal prostate cancer identifies multiple independent clonal expansions in neoplastic and morphologically normal prostate tissue

in Nature Genetics

47.

pp. 367–372

Full Text

(Letter)


Manson-Bahr, D., Ball, R., Gundem, G., Mills, R., Rochester, M., Goody, V., O'Meara, S., Flather, M., Keeling, M., Yazbek Hanna, M., Hurst, R., Curley, H., Clark, J., Brewer, D., Mcdermott, U., Cooper, C.

(2015)

Mutation Detection in Formalin-Fixed Prostate Cancer Biopsies Taken at the Time of Diagnosis Using Next Generation DNA Sequencing

in Journal of Clinical Pathology

68.

pp. 212-217

Full Text UEA Repository

(Article)


Gundem, G., Van loo, P., Kremeyer, B., Alexandrov, L., Tubio, J. M. C., Papaemmanuil, E., Brewer, D., Kallio, H., Högnäs, H., Annala, M., Kivinummi, K., Goody, V., Latimer, C., O'Meara, S., Dawson, K., Isaacs, W., Emmert-Buck, M. R., Nykter, M., Foster, C. S., Kote-Jarai, Z., Easton, D. F., Whitaker, H. C., Neal, D. E., Cooper, C., Eeles, R. A., Visakorpi, T., Campbell, P., Mcdermott, U., Wedge, D. C., Bova, G. S.

(2015)

The Evolutionary History of Lethal Metastatic Prostate Cancer

in Nature

520.

pp. 353–357

Full Text

(Letter)


Massie, C. E., Spiteri, I., Ross-Adams, H., Luxton, H. J., Kay, J., Whitaker, H. C., Dunning, M. J., Lamb, A. D., Ramos-Montoya, A., Brewer, D., Cooper, C., Eeles, R. A., Warren, A. Y., Tavaré, S., Neal, D. E., Lynch, A. G.

(2015)

HES5 silencing is an early and recurrent change in prostate tumourigenesis

in Endocrine-Related Cancer (ERC)

22.

pp. 131-144

Full Text UEA Repository

(Article)


Ju, Y. S., Tubio, J. M., Mifsud, W., Fu, B., Davies, H. R., Ramakrishna, M., Li, Y., Yates, L., Gundem, G., Tarpey, P. S., Behjati, S., Papaemmanuil, E., Martin, S., Fullam, A., Gerstung, M., Nangalia, J., Green, A. R., Caldas, C., Borg, Å., Tutt, A., Lee, M. T. M., Van't Veer, L. J., Tan, B. K., Aparicio, S., Span, P. N., Martens, J. W., Knappskog, S., Vincent-salomon, A., Børresen-dale, A., Eyfjörd, J. E., Flanagan, A. M., Foster, C., Neal, D. E., Cooper, C., Eeles, R., Lakhani, S. R., Desmedt, C., Thomas, G., Richardson, A. L., Purdie, C. A., Thompson, A. M., Mcdermott, U., Yang, F., Nik-zainal, S., Campbell, P. J., Stratton, M. R.

(2015)

Frequent somatic transfer of mitochondrial DNA into the nuclear genome of human cancer cells

in Genome Research

25.

pp. 814-824

Full Text UEA Repository

(Article)


Boutros, P. C., Fraser, M., Harding, N. J., De Borja, R., Trudel, D., Lalonde, E., Meng, A., Hennings-yeomans, P. H., Mcpherson, A., Sabelnykova, V. Y., Zia, A., Fox, N. S., Livingstone, J., Shiah, Y., Wang, J., Beck, T. A., Have, C. L., Chong, T., Sam, M., Johns, J., Timms, L., Buchner, N., Wong, A., Watson, J. D., Simmons, T. T., P'ng, C., Zafarana, G., Nguyen, F., Luo, X., Chu, K. C., Prokopec, S. D., Sykes, J., Dal Pra, A., Berlin, A., Brown, A., Chan-seng-yue, M. A., Yousif, F., Denroche, R. E., Chong, L. C., Chen, G. M., Jung, E., Fung, C., Starmans, M. H. W., Chen, H., Govind, S. K., Hawley, J., D'costa, A., Pintilie, M., Waggott, D., Hach, F., Lambin, P., Muthuswamy, L. B., Cooper, C., Eeles, R., Neal, D., Tetu, B., Sahinalp, C., Stein, L. D., Fleshner, N., Shah, S. P., Collins, C. C., Hudson, T. J., Mcpherson, J. D., Van Der Kwast, T., Bristow, R. G.

(2015)

Spatial genomic heterogeneity within localized, multifocal prostate cancer

in Nature Genetics

47.

pp. 736–745

Full Text UEA Repository

(Article)


Bettencourt-Silva, J. H., Clark, J., Cooper, C. S., Mills, R., Rayward-Smith, V. J., De La Iglesia, B.

(2015)

Building Data-Driven Pathways From Routinely Collected Hospital Data: A Case Study on Prostate Cancer

in JMIR Medical Informatics

3.

Full Text UEA Repository

(Article)


Ross-Adams, H., Lamb, A., Dunning, M., Halim, S., Lindberg, J., Massie, C., Egevad, L., Russell, R., Ramos-Montoya, A., Vowler, S., Sharma, N., Kay, J., Whitaker, H., Clark, J., Hurst, R., Gnanapragasam, V., Shah, N., Warren, A., Cooper, C., Lynch, A., Stark, R., Mills, I., Groenberg, H., Neal, D.

(2015)

Integration of copy number and transcriptomics provides risk stratification in prostate cancer: A discovery and validation cohort study

in EBioMedicine

2.

pp. 1133–1144

Full Text UEA Repository

(Article)


Merson, S., Yang, Z. H., Brewer, D., Olmos, D., Eichholz, A., McCarthy, F., Fisher, G., Kovacs, G., Berney, D. M., Foster, C. S., Møller, H., Scardino, P., Cuzick, J., Cooper, C. S., Clark, J.

(2014)

Focal amplification of the androgen receptor gene in hormone-naive human prostate cancer

in British Journal of Cancer

110.

pp. 1655-62

Full Text UEA Repository

(Article)


Tubio, J. M. C., Li, Y., Ju, Y. S., Martincorena, I., Cooke, S. L., Tojo, M., Gundem, G., Pipinikas, C. P., Zamora, J., Raine, K., Menzies, A., Roman-Garcia, P., Fullam, A., Gerstung, M., Shlien, A., Tarpey, P. S., Papaemmanuil, E., Knappskog, S., Van Loo, P., Ramakrishna, M., Davies, H. R., Marshall, J., Wedge, D. C., Teague, J. W., Butler, A. P., Nik-Zainal, S., Alexandrov, L., Behjati, S., Yates, L. R., Bolli, N., Mudie, L., Hardy, C., Martin, S., McLaren, S., O'Meara, S., Anderson, E., Maddison, M., Gamble, S., Foster, C., Warren, A. Y., Whitaker, H., Brewer, D., Eeles, R., Cooper, C., Neal, D., Lynch, A. G., Visakorpi, T., Isaacs, W. B., van't Veer, L., Caldas, C., Desmedt, C., Sotiriou, C., Aparicio, S., Foekens, J. A., Eyfjörd, J. E., Lakhani, S. R., Thomas, G., Myklebost, O., Span, P. N., Børresen-Dale, A., Richardson, A. L., Van de Vijver, M., Vincent-Salomon, A., Van den Eynden, G. G., Flanagan, A. M., Futreal, P. A., Janes, S. M., Bova, G. S., Stratton, M. R., McDermott, U., Campbell, P. J., Genome, Human, Mutagenesis, Insertional, Transduction, Genetic, Translocation, Genetic

(2014)

Mobile DNA in cancer. Extensive transduction of nonrepetitive DNA mediated by L1 retrotransposition in cancer genomes

in Science

345.

pp. 1251343

Full Text UEA Repository

(Article)


Zuo, J., Brewer, D., Arlt, V. M., Cooper, C., Phillips, D. H.

(2014)

Benzo[a]pyrene-induced DNA adducts and gene expression profiles in target and non-target organs for carcinogenesis in mice

in BMC Genomics

15.

Full Text UEA Repository

(Article)


Ju, Y. S., Alexandrov, L. B., Gerstung, M., Martincorena, I., Nik-Zainal, S., Ramakrishna, M., Davies, H. R., Papaemmanuil, E., Gundem, G., Shlien, A., Bolli, N., Behjati, S., Tarpey, P. S., Nangalia, J., Massie, C. E., Butler, A. P., Teague, J. W., Vassiliou, G. S., Green, A. R., Du, M., Unnikrishnan, A., Pimanda, J. E., Teh, B. T., Munshi, N., Greaves, M., Vyas, P., El-Naggar, A. K., Santarius, T., Collins, V. P., Grundy, R., Taylor, J. A., Hayes, D. N., Malkin, D., Foster, C. S., Warren, A. Y., Whitaker, H. C., Brewer, D., Eeles, R., Cooper, C., Neal, D., Visakorpi, T., Isaacs, W. B., Bova, G. S., Flanagan, A. M., Futreal, P. A., Lynch, A. G., Chinnery, P. F., McDermott, U., Stratton, M. R., Campbell, P. J.

(2014)

Origins and functional consequences of somatic mitochondrial DNA mutations in human cancer

in eLife

3.

pp. 1-28

Full Text UEA Repository

(Article)


Lalonde, E., Ishkanian, A. S., Sykes, J., Fraser, M., Ross-Adams, H., Erho, N., Dunning, M. J., Halim, S., Lamb, A. D., Moon, N. C., Zafarana, G., Warren, A. Y., Meng, X., Thoms, J., Grzadkowski, M. R., Berlin, A., Have, C. L., Ramnarine, V. R., Yao, C. Q., Malloff, C. A., Cooper, C.

(2014)

Tumour genomic and microenvironmental heterogeneity as integrated predictors for prostate cancer recurrence: a retrospective study

in The Lancet Oncology

15.

pp. 1521–1532

Full Text UEA Repository

(Article)


Cooper, C. A., Mulder, D. T., Allison, S. E., Pilar, A. V. C., Coombes, B. K.

(2013)

The SseC translocon component in Salmonella enterica serovar Typhimurium is chaperoned by SscA

in BMC Microbiology

13.

Full Text UEA Repository

(Article)


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