All Publications

Piddock, R. E., Marlein, C. R., Abdul-Aziz, A., Shafat, M. S., Auger, M. J., Bowles, K. M., Rushworth, S. A.

(2018)

Myeloma-derived macrophage inhibitory factor regulates bone marrow stromal cell-derived IL-6 via c-MYC,

in Journal of Hematology & Oncology

11

article no. 66

Full Text UEA Repository

(Article)

(Published)


Abdul-Aziz, A. M., Shafat, M. S., Sun, Y., Marlein, C. R., Piddock, R. E., Robinson, S. D., Edwards, D. R., Zhou, Z., Collins, A., Bowles, K. M., Rushworth, S. A.

(2018)

HIF1α drives chemokine factor pro-tumoral signaling pathways in acute myeloid leukemia,

in Oncogene

37

pp. 2676–2686

Full Text UEA Repository

(Article)

(Published)


Marlein, C. R., Zaitseva, L., Piddock, R. E., Robinson, S., Edwards, D., Shafat, M. S., Zhou, Z., Lawes, M., Bowles, K. M., Rushworth, S. A.

(2017)

NADPH oxidase-2 derived superoxide drives mitochondrial transfer from bone marrow stromal cells to leukemic blasts,

in Blood

130

(14)

pp. 1649-1660

Full Text UEA Repository

(Article)

(Published)


Butler, D. E., Marlein, C., Walker, H. F., Frame, F. M., Mann, V. M., Simms, M. S., Davies, B. R., Collins, A. T., Maitland, N. J.

(2017)

Inhibition of the PI3K/AKT/mTOR pathway activates autophagy and compensatory Ras/Raf/MEK/ERK signalling in prostate cancer,

in Oncotarget

8

pp. 56698-56713

Full Text UEA Repository

(Article)

(Published)


Piddock, R. E., Loughran, N., Marlein, C. R., Robinson, S. D., Edwards, D. R., Yu, S., Pillinger, G. E., Zhou, Z., Zaitseva, L., Auger, M. J., Rushworth, S. A., Bowles, K. M.

(2017)

PI3Kδ and PI3Kγ isoforms have distinct functions in regulating pro-tumoural signalling in the multiple myeloma microenvironment,

in Blood Cancer Journal

7

(3)

article no. e539

Full Text UEA Repository

(Article)

(Published)


Shafat, M. S., Oellerich, T., Mohr, S., Robinson, S. D., Edwards, D. R., Marlein, C. R., Piddock, R. E., Fenech, M., Zaitseva, L., Abdul-Aziz, A., Turner, J., Watkins, J. A., Lawes, M., Bowles, K. M., Rushworth, S. A.

(2017)

Leukemic blasts program bone marrow adipocytes to generate a protumoral microenvironment,

in Blood

129

(10)

pp. 1320-1332

Full Text UEA Repository

(Article)

(Published)