Anglo-Danish-Dutch study of Intensive Treatment of people with Newly diagnosed diabetes in primary care (ADDITION) : NIHR Health Technology Assessment. In collaboration with MRC Epidemiology Unit.

Diabetes is a common chronic condition associated with an increased risk of heart disease, stroke, amputation, visual impairment and kidney damage. Currently most people become diagnosed with diabetes when they develop symptoms or a complication, but there is evidence to suggest that the true onset occurs several years earlier.

This study aims to discover whether earlier detection and subsequent intensive treatment are worthwhile by quantifying the costs and benefits of such an approach. The study was set up in 2001 when 1,026 patients with diabetes were randomised at the practice level to either intensive treatment (a combination of medication and advice on lifestyle changes, for example diet and physical activity) or standard care according to current national guidelines.
Members of HEG are analysing the five year follow-up data to estimate the cost-effectiveness of intensive versus standard care. (Libo Tao, Ed Wilson).