Key Research Interests: Dietary Flavonoids, Micronutrients, Fatty Acids, Isothiocyanates, Dietary Patterns, Cardiovascular health, Musculoskeletal health, Cognition and dementia, Nutrigenomics and nutrigenetics, Inflammation, Biomarkers, Bioavailability

On-going research includes:

Dietary flavonoids and cardiovascular and metabolic health  - a  translational approach. We investigate their underlying physiological and molecular mechanisms, conduct randomised controlled trials and have long-term collaborations with well characterised prospective cohort studies including the Nurses' Health Study, the Health Professionals Follow-up Study, Framingham, Twins UK, EPIC-Norfolk.

Micronutrient research in the areas of iron bioavailability and selenium requirements for optimal health. This work uses a combination of cell/in vitro models and human studies and is conducted in collaboration with both national and international colleagues.

Fatty acids and cardiovascular health with a particular focus on n-3 PUFAs and their impact on the blood lipid profile and vascular biology.

Bioavailability and metabolism of a range of dietary constituents using isotopic labelling in humans and in vitro model approaches.

Evaluating public health interventions.

Dietary patterns, dietary constituents and muscle and bone health.

Examining the bioactivity of isothiocyanates from cruciferous vegetables in relation to chemoprevention.

Nutrigenetics – using both GWAS and candidate gene approaches to establish the impact of common gene variants on disease risk and response to diet. There is a current focus on APOE genotype in cardiovascular and cognitive health.

Developing interest on the impact of dietary constituents on cognitive function.