| Job Title | Contact | Location |
|---|---|---|
| Honorary Senior Lecturer | K dot Bowles at uea dot ac dot uk |
Rushworth, S, Bowles, KM, Barrera Briceno, LN, Murray, MY, Zaitseva, L and Macewan, DJ (2013) BTK inhibitor ibrutinib is cytotoxic to myeloma and potently enhances bortezomib and lenalidomide activities through NF-κB. Cellular Signalling, 25 (1). pp. 106-112.
Barrera Briceno, LN, Rushworth, SA, Bowles, KM and Macewan, DJ (2012) Bortezomib induces heme oxygenase-1 expression in multiple myeloma. Cell Cycle, 11 (12). pp. 2248-2252. ISSN 1538-4101
Rushworth, SA, Zaitseva, L, Murray, MY, Shah, NM, Bowles, KM and Macewan, DJ (2012) The high Nrf2 expression in human acute myeloid leukemia is driven by NF- B and underlies its chemo-resistance. Blood, 120 (26). pp. 5188-5198. ISSN 0006-4971
Heasman, S-A, Zaitseva, L, Bowles, KM, Rushworth, SA and Macewan, DJ (2011) Protection of acute myeloid leukaemia cells from apoptosis induced by front-line chemotherapeutics is mediated by haem oxygenase-1. Oncotarget, 2. pp. 658-668.
Heasman, S-A, Zaitseva, L, Bowles, K, Rushworth, SA and Macewan, DJ (2011) Heme oxygenase-1 protects acute myeloid leukaemia cells from front line chemotherapeutic drugs. Basic & Clinical Pharmacology & Toxicology, 109. p. 96.
Rushworth, SA, Bowles, KM and Macewan, DJ (2011) Elevated NRF2 levels in acute myeloid leukaemia reduces sensitivity towards proteasome inhibitors. Basic & Clinical Pharmacology & Toxicology, 109. p. 31.
Rushworth, SA, Bowles, KM and Macewan, DJ (2011) High Basal Nuclear Levels of Nrf2 in Acute Myeloid Leukemia Reduces Sensitivity to Proteasome Inhibitors. Cancer Research, 71 (5). pp. 1999-2009. ISSN 0008-5472
Rushworth, Stuart A, Bowles, KM, Raninga, P. and Macewan, David J (2010) NF- B-Inhibited Acute Myeloid Leukemia Cells Are Rescued from Apoptosis by Heme Oxygenase-1 Induction. Cancer Research, 70 (7). pp. 2973-2983. ISSN 0008-5472
Rushworth, SA, Zaitseva, L, Langa Marcano, S, Bowles, KM and Macewan, DJ (2010) FLIP regulation of HO-1 and TNF signalling in human acute myeloid leukemia provides a unique secondary anti-apoptotic mechanism. Oncotarget, 1 (5). pp. 359-366. ISSN 1949-2553
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