Article

Wang, Q, Bao, Y, Zhang, X, Coxon, P, Jayasooriya, UA and Chao, Y (2012) Uptake and toxicity of poly-acrylic acid functionalized silicon nanoparticles in cultured mammalian cells. Adv Health Materials, 1 (2). pp. 189-198.

Barrera, LN, Cassidy, A, Wei, T, Wang, W, Belshaw, N, Johnson, I, Brigelius-Flohe, R and Bao, Y (2012) TrxR1 and Gpx2 are potently induced by isothiocyanates and selenium, and mutually cooperate to protect Caco-2 cells against free radical-mediated cell death. BBA-Molecular Cell Research, 1823. pp. 1914-1924.

Barrera, LN, Johnson, IT, Bao, Y, Cassidy, A and Belshaw, N (2012) Colorectal cancer cells Caco-2 and HCT116 resist epigenetic effects of isothiocyanates and selenium in vitro. European Journal of Nutrition. (In Press)

Barrera , LN, Cassidy, A, Johnson, Ian T., Bao, Y and Belshaw, NJ (2012) Epigenetic and antioxidant effects of dietary isothiocyanates and selenium: potential implications for cancer chemoprevention. Proceedings of the Nutrition Society, 71. pp. 237-245. ISSN 0029-6651

Li, D, Wang, W, Barrera, L, Howie, AF, Beckett, G, Wu, K and Bao, Y (2012) Synergy between sulforaphane and selenium in the up-regulation of thioredoxin reductase and protection against hydrogen peroxide-induced cell death in human hepatocytes. Food Chemistry, 133 (2). pp. 300-307.

Shan, Y, Zhang, L, Bao, Y, Li, B, He, C, Gao, M, Feng, X, Xu, Weiping, Zhang, X and Wang, S (2012) Epithelial-mesenchymal transition, a novel target of sulforaphane via COX-2/MMP2,9/Snail, ZEB1 and miR-200c/ZEB1 pathways in human bladder cancer cells. The Journal of Nutritional Biochemistry. (In Press)

Wang, Q, Bao, Y, Ahire, J and Chao, Y (2012) Co-encapsulation of Biodegradable Nanoparticles with Silicon Quantum Dots and Quercetin for Monitored Delivery. Advanced Healthcare Materials. n/a-n/a. ISSN 21922640 (In Press)

Wang, Q, Bao, Y and Chao, Y (2012) Nanoencapsulation of biodegradable nanoparticles for monitored delivery of quercetin. Advanced Health Materials. (In Press)

Warwick, E, Cassidy, A, Hanley, B, Jouni, ZE and Bao, Y (2012) Effect of phytochemicals on phase II enzyme expression in infant human primary skin fibroblast cells. British Journal of Nutrition. pp. 1-8. ISSN 0007-1145

Fairweather-Tait, Susan J, Bao, Yongping, Broadley, Martin R., Collings, Rachel, Ford, Dianne, Hesketh, John E. and Hurst, Rachel (2011) Selenium in Human Health and Disease. Antioxidants & Redox Signaling, 14. pp. 1337-1383. ISSN 1523-0864

Goldson, AJ, Fairweather-Tait, SJ, Armah, CA, Bao, Y, Broadley, MR, Dainty, JR, Furniss, C, Hart, DJ, Teucher, B and Hurst, R (2011) Effects of selenium supplementation on selenoprotein gene expression and response to influenza challenge: a randomized controlled trial. PloS ONE, 6 (3). e14771.

Wang, Qi, Ni, Hongjun, Pietzsch, Annette, Hennies, Franz, Bao, Yongping and Chao, Yimin (2011) Synthesis of water-dispersible photoluminescent silicon nanoparticles and their use in biological fluorescent imaging. Journal of Nanoparticle Research, 13 (1). pp. 405-413.

Shan, Y, Wang, X, Wang, W, He, C and Bao, Y (2010) p38 MAPK plays a distinct role in sulforaphane-induced up-regulation of ARE-dependent enzymes and down-regulation of COX-2 in human bladder cancer cells. Oncol Rep, 23 (4). pp. 1133-1138.

Shan, Y, Wu, K, Wang, W, Wang, S, Lin, N, Zhao, R, Cassidy, A and Bao, Y (2009) Sulforaphane down-regulates COX-2 expression by activating p38 and inhibiting NF-kappaB-DNA-binding activity in human bladder T24 cells. International Journal of Oncology, 34 (4). pp. 1129-1134.

Sun, H, Hans, FS, Bao, Y, Guo, L, Gao, YH, Zhou, LW and Zhing, XK (2009) Effects of acute virus infection on expression of gp130 mRNA and protein in mouse myocytes. Chinese J. Clinical Medicine, 16. pp. 689-691.

Li, D, Wu, K, Howie, A, Beckett, G, Wang, W and Bao, Y (2008) Synergy between Broccoli Sprout Extract and Selenium in the Upregulation of Thioredoxin Reductase in Human Hepatocytes. Food Chemistry, 110 (1). pp. 193-198.

Mastrangelo, L, Cassidy, A, Mulholland, F, Wang, W and Bao, Y (2008) Serotonin Receptors, Novel Targets of Sulforaphane Identified by Proteomic Analysis in Caco-2 Cells. Cancer Research, 68 (13). pp. 5487-5491.

Bacon, J, Plumb, GW, Howie, A, Beckett, G, Wang, W, Bao, Y, Navarro, C, Quiros, JR and Palli, D (2007) Dual Action of Sulforaphane in the Regulation of Thioredoxin Reductase and Thioredoxin in Human HepG2 and Caco-2 Cells. Journal of Agricultural and Food Chemistry, 55 (4). pp. 1170-1176.

Sun, H, Gao, L, Zhou, L, Liu, Y, Pang, B, Bao, Y and Zhong, XK (2007) Effects of sulforaphane on phase II enzymes activity and nitrogen monoxidum level Se-deficient mice with virus induced myocardiopathy. Chinese Journal of Endemiology, 26 (4). pp. 372-374. ISSN 1000-4955

Jakubikova, J, Bao, Y, Bod'o, J and Sedlák, J (2006) Isothiocyanate iberin modulates phase II enzymes, posttranslational modification of histones and inhibits growth of Caco-2 cells through induction of apoptosis. Neoplasma, 53. pp. 463-470.

Jakubikova, J, Sedlák, J, Bod'o, J and Bao, Y (2006) Effect of isothiocyanates on nuclear accumulation of NF-kappaB, Nrf2, and thioredoxin in caco-2 cells. Journal of Agricultural and Food Chemistry, 54 (5). pp. 1656-1662.

Shan, Y, Sun, C, Zhao, X, Wu, K, Cassidy, A and Bao, Y (2006) Effect of sulforaphane on cell growth, G(0)/G(1) phase cell progression and apoptosis in human bladder cancer T24 cells. International Journal of Oncology, 29 (4). pp. 883-888.

Bao, Y (2005) Bioactivities of dietary isothiocyanates. Agro Food Industry hi-tech, 16 (3). pp. 24-26.

Bao, Y, Jakubikova, J, Sedlák, J, Bacon, J and Mithen, R (2005) MAPK and P13K signaling pathways in isothiocyanates-induced gene expression, G2/M arrest and apoptosis. Proceedings of the American Association of Cancer Research, 46 (1). p. 565.

Chen, K, Plumb, G, Bennett, RN and Bao, Y (2005) Antioxidant activities of extracts from five anti-virus medicinal plants. Journal of Ethnopharmacology, 96 (1-2). pp. 201-205.

Jakubikova, J, Bao, Y and Sedlák, J (2005) Isothiocyanates induce cell cycle arrest, apoptosis and mitochondrial potential depolarization in HL-60 and multidrug-resistant cell lines. Anticancer Research, 25 (5). pp. 3375-3386.

Jakubikova, J, Sedlák, J, Bacon, J, Goldson, A and Bao, Y (2005) Effects of MEK1 and PI3K inhibitors on allyl-, benzyl- and phenylethyl-isothiocyanate-induced G2/M arrest and cell death in Caco-2 cells. International Journal of Oncology, 27 (5). pp. 1449-1458.

Jakubiková, J, Sedlák, J, Mithen, R and Bao, Y (2005) Role of PI3K/Akt and MEK/ERK signaling pathways in sulforaphane - and erucin- induced phase II enzymes and MRP2 transcription, G2/M arrest and cell death in Caco-2 cells. Biochemical Pharmacology, 69 (11). pp. 1543-1552.

Traka, M, Gasper, AV, Smith, JA, Hawkey, CJ, Bao, Y and Mithen, RF (2005) Transcriptome analysis of human colon Caco-2 cells exposed to sulforaphane. Journal of Nutrition, 135 (8). pp. 1865-1872.

Wang, W, Wang, SA, Howie, F, Beckett, G, Mithen, R and Bao, Y (2005) Sulforaphane, erucin and iberin up-regulate thioredoxin reductase 1 expression in human MCF-7 cells. Agri Food Chem, 53 (5). pp. 1417-1421.

Bacon, J, Garner, C, Lappin, G and Bao, Y (2004) Dietary micronutrients modulate phIP-DNA adduct formation in human Hep G2 cells. Mutagenesis, 16 (6). p. 512.

De Pascual-Teresa, S, Johnston, KL, DuPont, MS, Leary, KA, Needs, PW, Morgan, LM, Clifford, MN, Bao, Y and Williamson, G (2004) Regulation of cyclooxygenase-2 transcription in human lymphocytes by quercetin conjugates ex vivo and in vivo. Journal of Nutrition, 134. pp. 552-557.

Lee, G, Lund, E, Bao, Y, Rhodes, M and Johnson, I (2004) Cylooxygenase-2 (COX-2) gene expression and prostaglandin production is decreased in human adenocarcinoma cells after treatment with physiological doses of eicosapentaenoic acid. Gastroenterology, 126.

O'Leary, KA, De Pascual-Teresa, S, Needs, P, Bao, Y, O'Brien, N and Williamson, G (2004) Effect of flavonoids and vitamin E on cyclo-oxygenase-2 (COX-2) transcription. Mutation Research, 551. pp. 245-254.

Sun, H, Bao, Y, Goa, L, Guo, L, Wang, Y, Zhou, L, Liu, Y and Zhong, XK (2004) Effect of Sulforaphane on Coxsakievirus B3m - induced myocardiopathy in Se-deficient mice. Chinese Journal of Endemiology, 23. pp. 412-414.

Svehlikova, V, Bennett, RN, Mugford, M, Mellon, FA, Needs, PW, Piacente, S, Kroon, PA and Bao, Y (2004) Isolation, identification and stability of acylated derivatives of apigenin 7-O-glucoside from chamomile (Chamomilla recutita [L.] Rauschert). Phytochemistry, 65 (16). pp. 2323-2332.

Svehlikova, V, Wang, S, Jakubikova, J, Williamson, G, Mithen, R and Bao, Y (2004) Interactions between sulforaphane and apigenin in the induction of UGT1A1 and GSTA1 in CaCo-2 cells. Carcinogenesis, 25 (9). pp. 1629-1637.

Zhang, J, Wang, H, Bao, Y and Zhang, L (2004) Nano red elemental selenium has no size effect in the induction of seleno-enzymes in both cultured cells and mice. Life Sciences, 75 (2). pp. 237-244.

Bacon, J and Bao, Y (2003) Effect of Sulforaphane and quercetin on phIP - DNA adduct formation in human Hep G2 and hepatocytes. Pharmacology and Toxicology, 93 (1). pp. 21-22.

Bacon, J, Williamson, G, Garner, C, Lappin, G, Langouet, S and Bao, Y (2003) Sulforaphane and quercetin modulate phIP-DNA adduct formation in human Hep G2 and hepatocytes. Carcinogenesis, 24 (12). pp. 1903-1911.

Petri, N, Tannergren, C, Holst, B, Mellon, FA, Bao, Y, Plumb, GW, Bacon, J, O'Leary, KA, Kroon, PA, Knutson, L, Forsell, P, Eriksson, T, Lennernas, H and Williamson, G (2003) Absorption/metabolism of sulforaphane and quercetin, and regulation of phase II enzymes, in human jejunum in vivo. Drug Metab Dispos, 31 (6). pp. 805-813.

Zhang, J, Svehlikova, V, Bao, Y, Howie, A, Beckett, G and Williamson, G (2003) Synergy between sulforaphane and selenium in the induction of thioredoxin reductase 1 requires both transcriptional and translational modulation. Carcinogenesis, 24 (3). pp. 497-503.

Bao, Y (2002) Nutrition Research in the post-genome-sequencing era. Chinese Science Bulletin, 17.

Bao, Y, Bacon, J and Williamson, G (2002) Protective effect of phytochemicals on PhIP-DNA adduct formation.

Bao, Y and Williamson, G (2002) Quantification of mRNA by RT-competitive-PCR and high performance liquid chromatography. Progress in Natural Science, 12. pp. 353-358.

Basten, GP, Bao, Y and Williamson, G (2002) Sulforaphane and its glutathione conjugate but not sulforaphane nitrile induce UDP-glucuronosyl transferase (UGT1A1) and glutathione transferase (GSTA1) in cultured cells. Carcinogenesis, 23 (8). pp. 1399-1404.

Zhang, J, Gao, Y, Zhang, L and Bao, Y (2001) Biological effects of a nano red elemental selenium. Biofactors, 15 (1). pp. 27-38.

Day, AJ, Bao, Y, Morgan, MR and Williamson, G (2000) Conjugation position of quercetin glucuronides and effect on biological activity. Free Radical Biology & Medicine, 29 (12). pp. 1234-1243.

Book Section

Bacon, J and Bao, Y (2004) Phytochemicals protect against heterocyclic amine-induced DNA adduct formation in: Pytochemicals in Health and Disease. In: Phytochemicals in Health and Disease. Marcel Dekker Inc, pp. 143-162. ISBN 0824740238

Bao, Y (2004) Future perspectives in phytochemical and health research. In: Phytochemicals in Health and Disease. Marcel Dekker Inc, pp. 331-342. ISBN 0824740238

Elliott, R, Bacon, J and Bao, Y (2004) Nutritional Genomics. In: Phytochemicals in Health and Disease. Marcel Dekker Inc, pp. 1-23. ISBN 0824740238

Ong, C, Halliwell, B, Williamson, G, Bao, Y, Chen, K and Bucheli, P (2004) Effects of phytochemicals in Chinese functional ingredients on gut health. In: Herbal Medicine and Molecular Basis in Health and Disease Management. Marcel Decker Inc. ISBN 0824752082

Bao, Y, Bacon, J and Williamson, G (2001) Effect of phytochemicals on phIP-DNA adduct formation in human HepG2 cells and hepatocytes. In: Biologically-active Phytochemicals in Food. Royal Society of Chemistry. ISBN 0854048065

Bao, Y Phytochemicals and nutrition in specific people. In: Nutritional requirements for Special People. People's Medical Publishing House, Beijing.

Conference or Workshop Item

WIlliams, F, Davidson, R, Skinner, J, Culley, K, Bao, YP, Cassidy, A, Clark, I and Macgregor, A (2009) Epidemiological and Molecular Evidence for the Chondroprotective Effect of Garlic in Osteoarthritis. In: Annual Meeting of the British-Society-of-Rheumatology, April 28 - May 01 2009, Glasgow, Scotland.

Bao, Y (2005) Phytochemicals and Human Health - Bioactivity of dietary isothiocyanates. In: SMI Nutraceuticals and Functional Foods Conference, London, UK.

Bao, Y, Jakubikova, J and Sedlák, J (2005) MAPK and P13K signalling pathways in isothiocyanate-induced gene expression, G2 /M arrest and cell death. In: American Association of Cancer Research meeting, Anaheim CA, USA.

Jakubikova, J, Sedlák, J, Mithen, R and Bao, Y (2004) Cellular signaling pathways in isothicyanates - G2/M arrest and apoptosis. In: 12th ECDO Euroconference on Apoptosis, Chania, Greece.

Tesfaye, W, Bao, Y, Bennett, RN, Garcia-Parrilla, MC and Troncoso, AM (2004) Red wine polyphenols and gene expression. In: XXII International conference on polyphenols, Helsinki, Finland.

Bacon, J and Bao, Y (2003) Effects of sulforaphane and quercetin on phIP-DNA adduct formation in human Hep G2 cells and hepatocytes. In: The 7th Nordic Conference on Toxicology and Environmental Mutagenesis, Bornholm, Denmark.

Bacon, J, Bao, Y and Williamson, G (2002) Dietary phytochemicals protect against DNA damage in human liver cells PS 5-046. In: 28th Meeting of the Federation of the European Biochemical Societies, Istanbul, Turkey.

Bao, Y, Bacon, J and Williamson, G (2002) Protective effect of phytochemicals on phIP-DNA adduct formation. In: International Symposium on Dietary Phytochemicals and Human Health, Salamanca Spain.

Hurst, R, Bao, Y, Williamson, G, Girotti, A, Korytowski, W and Kriska, T (2002) Overexpression of a selenoprotein protects cells against peroxidative injury and apoptosis. In: TEMA 11 presented at Trace Elements in Man and Animals.

Bao, Y (2001) New approaches to assess biological effects of dietary phytochemicals. In: The 2nd Symposium on Natural Antioxidants, Beijing, China.

Bao, Y, Bacon, J and Williamson, G (2001) Effect of phytochemicals on phIP-DNA adduct formation in human Hep G2 and hepatocytes. In: EUROFOODCHEM XI: Biologically active Phytochemicals in Food:analysis metabolism bioavailability and .

Zhang, J, Gao, X, Zhang, L and Bao, Y (2001) Antioxidative and oxidative activities of nano red elemental selenium. In: The 2nd International Symposium of Natural Antioxidants Molecular Mechanisms and Health Effects, Bei.

Book

Bao, Y and Fenwick, R (2004) Phytochemicals in Health and Disease. Marcel Dekker Inc. ISBN 0824740238