|Clinical Senior Lecturer||
Chris dot Fox at uea dot ac dot uk
Tel: +44 (0)1603 59 3583
|(43) Floor 2|
My research interests cover a wide range from bioscience through epidemiology, psychological interventions and health services research. My main areas of work have involved evidence based mental health, pharmacological and non-pharmacological interventions in dementia, collaborative projects in neurology and UK/US studies in dementia; both interventions and outcome research at the interface of primary and secondary care. I have been involved in 6 clinical trials of investigational medicinal products as lead and Co-investigator.
Currently I am pursuing a research strategy of novel medication usage for dementia, health service research in the UK and USA in dementia and protection of cognition in vulnerable hospitalised elders.
I spent 6 years researching trauma/personality assessments and treatment and psychometric assessment development with the Ministry of Defence. Then I went into the NHS and undertook and MD on anger characterisation in elderly mentally ill.
In the last 10 years I undertook 2 Cochrane reviews in dementia. In 2004 I set UK/US collaborations with colleagues which are ongoing. We have jointly co-developed work on the harms of screening, medication trials in dementia, collaborative care in dementia and the anticholinergic burden scale.
I worked as a consultant for 9 years and developed an applied research strategy. I am presently working on funded projects on collaborative care in dementia, screening in dementia, inpatient rehabilitation in dementia and assistive technology in dementia.
Professional Qualifications and professional memberships
MBBS; Bsc; Mmedsci; MRCPsych; MD
· Mental Health Research
· Dementia Health Service Research
· Clinical Trials of Investigational Medicinal Products
· Delirium and Hospital Care
· Medication Management
· International Collaborative Research
· Assistive Technology in Dementia
· Evidence based practice Medicine
Campbell N, Boustani M, Limbil T, Fox C, Ott C, Maidment I, Schubert C, Munger S, Fick D, Miller D, Gulati R. (2009). The Cognitive Impact of Anticholinergics: A Clinical review. Clinical Intervention in Aging 4, 225–233 .
Shotbolt P, Samuel M, Fox C, David A. (2009). A randomized controlled trial of quetiapine for psychosis in Parkinson’s disease. Neuropsychiatric Disease and Treatment 5, 327–332.
Banerjee S, Hellier J, Dewey M, Romeo R, Ballard C, Baldwin R, Bentham P, Fox C et al. Sertraline or mirtazapine for depression in dementia (HTA-SADD): a randomised, multicentre, double-blind, placebo-controlled trial. Lancet. 2011 Jul 30;378(9789):403-11
Fox C, Richardson, K Maidment I, Smithard D, Katona C, Boustani M, Savva G M, Coulton S, Matthews F E, l Brayne C on behalf of the Medical Research Council Cognitive Function and Ageing Study (MRC CFAS) Anticholinergic Medication Use and Cognitive Impairment in the Older Population: The Medical Research Council Cognitive Function and Ageing Study. J Am Geriatr Soc. 2011 Jun 24
Fox C, Livingston G, Maidment I, Coulton S, Smithard D, Boustani M, Katona C. 2011. The impact of anticholinergic burden in Alzheimer’s dementia-The laser AD study-Age and Aging 40(6):730-5.
· Research methods and engagement
Banerjee, S, Hellier, J, Romeo, R, Dewey, M, Knapp, M, Ballard, C, Baldwin, R, Bentham, P, Fox, C and et al, (2013) Study of the use of antidepressants for depression in dementia: the HTA-SADD trial - a multicentre, randomised, double-bind, placebo-controlled trial of the clinical effectiveness and cost-effectiveness of sertraline and mirtazapine. Health Technol Assess, 17 (7). pp. 1-166.
Khan, BA, Zawahiri, M, Campbell, NL, Fox, C, Weinstein, EJ, Nazir, A, Farber, MO, Buckley, JD, MacLullich, A and Boustani, MA (2012) Delirium in hospitalized patients: Implications of current evidence on clinical practice and future avenues for research-A systematic evidence review. Journal of Hospital Medicine, 7 (7). pp. 580-589. ISSN 15535592
Rolinski, M, Fox, C, Maidment, I and McShane, R (2012) Cholinesterase inhibitors for dementia with Lewy bodies, Parkinson's disease dementia and cognitive impairment in Parkinson's disease. Cochrane Database of Systematic Reviews .
Smithard, DG, Fox, C, Maidment, ID, Katona, C and Boustani, M (2012) Do anticholinergic drugs contribute to functional and cognitive decline? Aging Health, 8 (1). pp. 57-60. ISSN 1745-509X
Breitner, JCS, Fox, C, Crugel, M, Maidment, I, Auestad, BH, Coulton, S, Treloar, A, Ballard, C, Boustani, M, Katona, C and Livingston, G (2012) Efficacy of Memantine for Agitation in Alzheimer’s Dementia: A Randomised Double-Blind Placebo Controlled Trial. PLoS ONE, 7 (5). e35185. ISSN 1932-6203
Child, A, Clarke, A, Fox, C and Maidment, I (2012) A pharmacy led program to review anti-psychotic prescribing for people with dementia. BMC Psychiatry, 12 (1). p. 155. ISSN 1471-244X
Koch, T, Iliffe, S, Manthorpe, J, Stephens, B, Fox, C, Robinson, L, Livingston, G, Coulton, S, Knapp, M, Chew-Graham, C and Katona, C (2012) The potential of case management for people with dementia: a commentary. International Journal of Geriatric Psychiatry. n/a-n/a. ISSN 08856230
Romeo, R, Knapp, M, Hellier, J, Dewey, M, Ballard, C, Baldwin, R, Bentham, P, Burns, A, Fox, C, Holmes, C, Katona, C, Lawton, C, Lindesay, J, Livingston, G, McCrae, N, Moniz-Cook, E, Murray, J, Nurock, S, O'Brien, J, Poppe, M, Thomas, A, Walwyn, R, Wilson, K and Banerjee, S (2012) Cost-effectiveness analyses for mirtazapine and sertraline in dementia: randomised controlled trial. The British Journal of Psychiatry. pp. 1-8. ISSN 0007-1250
Fox, C, Livingston, G, Maidment, ID, Coulton, S, Smithard, DG, Boustani, M and Katona, C (2011) The impact of anticholinergic burden in Alzheimer's Dementia-the Laser-AD study. Age and Ageing, 40 (6). pp. 730-735. ISSN 0002-0729
Fox, C, Richardson, K, Maidment, ID, Savva, GM, Matthews, FE, Smithard, D, Coulton, S, Katona, C, Boustani, MA and Brayne, C (2011) Anticholinergic Medication Use and Cognitive Impairment in the Older Population: The Medical Research Council Cognitive Function and Ageing Study. Journal of the American Geriatrics Society, 59 (8). pp. 1477-1483. ISSN 00028614
Banerjee, S, Hellier, J, Dewey, M, Romeo, R, Ballard, C, Baldwin, R, Bentham, P, Fox, C, Holmes, C, Katona, C, Knapp, M, Lawton, C, Lindesay, J, Livingston, G, McCrae, N, Moniz-Cook, E, Murray, J, Nurock, S, Orrell, M, O'Brien, J, Poppe, M, Thomas, A, Walwyn, R, Wilson, K and Burns, A (2011) Sertraline or mirtazapine for depression in dementia (HTA-SADD): a randomised, multicentre, double-blind, placebo-controlled trial. The Lancet, 378 (9789). pp. 403-411. ISSN 01406736
Maidment, ID, Fox, C, Boustani, M and Katona, C (2011) Medication management-the missing link in dementia interventions. International Journal of Geriatric Psychiatry (Epub ahead of print). ISSN 08856230
Gaskell, H, Burns, A, Fox, C, Maidment, I, Pettit, TACL, Wild, R, McShane, R, Boustani, M and Gaskell, H (2011) Cholinesterase inhibitors for dementia with Lewy bodies, Parkinson's disease dementia and cognitive impairment in Parkinson's disease. Cochrane Database of SystematicReviews 2011. (In Press)
Treloar, A., Crugel, M., Prasanna, A., Solomons, L., Fox, C., Paton, C. and Katona, C. (2010) Ethical dilemmas: should antipsychotics ever be prescribed for people with dementia? The British Journal of Psychiatry, 197 (2). pp. 88-90. ISSN 0007-1250
Campbell, N, Boustani, M, Ayub, A, Fox, C, Munger, S, Ott, C, Guzman, O, Farber, M, Ademuyiwa, A and Singh, R (2009) Pharmacological Management of Delirium in Hospitalized Adults - A Systematic Review. Journal of Internal Geriatric Medicine, 24 (7). pp. 848-853.
Campbell, Noll, Boustani, Malaz, Limbil, Tony, Ott, Carol, Fox, Chris, Maidment, Ian, Schubert, Cathy C, Munger, Stephanie, Fick, Donna, Miller, David and Gulati, Rajesh (2009) The cognitive impact of anticholinergics: a clinical review. Clinical interventions in aging, 4. pp. 225-233. ISSN 1178-1998
Fox, Chris, Boustani, Malaz and Moniz-Cook, Esme (2009) Treatment of dementia: where is it going? British Journal of Hospital Medicine (London, England : 2005), 70 (8). pp. 450-455. ISSN 1750-8460
Fox, GC, Moniz-Cooke, M and Boustani, M (2009) Dementia. British Journal of Hospital Medicine, 70 (8). pp. 234-239.
Justiss, MD, Fox, C, Katona, C, Perkins, AJ, Healey, PJ, Sachs, G, Hui, S, Callahan, CM, Hendrie, HC and Scott, E (2009) Patients' attitudes of dementia screening across the Atlantic. International Journal of Geriatric Psychiatry, 24. pp. 632-637.
Shotbolt, Paul, Samuel, Michael, Fox, Chris and David, Anthony S (2009) A randomized controlled trial of quetiapine for psychosis in Parkinson disease. Neuropsychiatric Disease and Treatment. pp. 327-332. ISSN 1176-6328
Boustani, M, Perkins, AJ, Monahan, P, Fox, C, Watson, L, Hopkins, J, Fulz, B, Hui, S, Unverzagt, FW, Callahan, CM and Hendrie, HC (2008) Measuring primary care patients' attitudes about dementia screening. International Journal of Geriatric Psychiatry, 23 (8). pp. 812-820.
Boustani, Malaz, Campbell, Noll, Munger, Stephanie, Maidment, Ian and Fox, Chris (2008) Impact of anticholinergics on the aging brain: a review and practical application. Aging Health, 4 (3). pp. 311-320. ISSN 1745-509X
Campbell, N, Ayub, A, Boustani, M, Fox, C, Farlow, M, Maidment, I and Howard, R (2008) Impact of cholinesterase inhibitors on behavioural and psychological symptoms of Alzheimer's disease: A meta-analysis. Clinical Interventions in Aging, 3 (4). pp. 719-728.
Maidment, I, Brown, R, Rodriguez,, Boustani, M, Katona, C and Fox, C (2008) Memantine in Agitation in Dementia. The Annals of Pharmacotherapy, 42 (1). pp. 32-38.
Maidment, Ian D, Haw, Camilla, Stubbs, Jean, Fox, Chris, Katona, Cornelius and Franklin, Bryony Dean (2008) Medication errors in older people with mental health problems: a review. International journal of geriatric psychiatry, 23 (6). pp. 564-73. ISSN 0885-6230
Brayne, C, Fox, C and Boustani, M (2007) Dementia screening in primary care: is it time? JAMA : the journal of the American Medical Association, 298 (20). pp. 2409-11. ISSN 1538-3598
Fox, C, Maidment, I, Boustani, M and Katona, C (2006) Memantine combined with cholinesterase inhibitors - Hope for the future? Neuropsychiatric Disease and Treatment, 2 (2). pp. 121-125.
Ballard, C and Fox, C (2006) Effectiveness of collaborative care for elderly adults with Alzheimer's disease in primary care. The Lancet Neurology, 5 (8). pp. 644-645.
Boustani, M, Perkins, A, Fox, C, Unverzagt, F, Hendrie, H, Siu, H, Foltz, B and Callaghan, C (2006) Who refuses dementia assessment in Primary Care? International Journal of Geriatric Psychiatry, 21 (6). pp. 556-563. ISSN 0885-6230
Samuel, M, Maidment, I, Boustaini, M and Fox, C (2006) Psychiatric Aspects of Parkinson's Disease Dementia. Advances in Applied Ceramics: Structural, Functional and Bioceramics Journal - Advances in Psychiatric Treatment, 12. pp. 121-129. ISSN 1743-6753
Schubert, CC, Boustani, M, Callahan, CM, Perkins, AJ, Carney, CP, Fox, C, Unverzagt, F, Hui, S and Hendrie, HC (2006) Comorbidity Profile of Dementia Patients in Primary Care: Are They Sicker? Journal of the American Geriatrics Society, 54 (1). pp. 104-109. ISSN 00028614
Maidment, I, Fox, C, Livingston, G and Katona, C (2005) Drug treatment for Alzheimer's disease: the way forward. International Journal of Geriatric Psychiatry, 21 (1). pp. 6-8. ISSN 0885-6230
Maidment, ID, Fox, C and Boustani, M (2005) A review of studies describing the use of acetyl cholinesterase inhibitors in Parkinson's disease dementia. Acta Psychiatrica Scandinavica, 111 (6). pp. 403-409. ISSN 0001-690X
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