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Academic

Dr Andrew Wilson

Andrew Wilson
Job Title Contact Location
Clinical Senior Lecturer  A dot M dot Wilson at uea dot ac dot uk
Tel: +44 (0)1603 59 1257  
 
  • Personal
  • Research
  • Teaching
  • Publications
  • External
  • Admin

Career

  • 1 November 2004 to Present Clinical Senior Lecturer in Respiratory Health, University of East Anglia, Norwich and Honorary Consultant Physician in Respiratory Medicine, Norfolk and Norwich University Hospital, Colney Lane, Norwich, NR4 7UY.
  • 1 June 2003 – 1 November 2004 Clinical Lecturer and Honorary Specialist Registrar in Clinical Pharmacology, Respiratory Medicine and General Medicine, Department of Medicine and Therapeutics, Ninewells Hospital & Medical School, University of Dundee, DUNDEE
  • 1 June 2002 – 1 June 2003 Clinical Fellow to Prof AE Holbrook, Prof FE Hargreave and PM O’Byrne. McMaster University 1200 Main Street, Hamilton Ontario Canada L8N 3Z5.
  • 1 June 1998 – 1 June 2002 Clinical Lecturer and Honorary Specialist Registrar in Clinical Pharmacology, Respiratory Medicine and General Medicine, Department of Clinical Pharmacology and Therapeutics, Ninewells Hospital & Medical School, University of Dundee, DUNDEE
  • 1 August 1996- 1 June 1998 Clinical Research Fellow in Clinical Pharmacology and Honorary Registrar at Department of Clinical Pharmacology and Therapeutics, Ninewells Hospital & Medical School, University of Dundee, DUNDEE
  • 1 August 1994 – 31 July 1996 Senior House Officer in Medical Rotation at Salford Royal Hospitals NHS Trust, SALFORD
  • 1 August 1993- 31 August 1994 Senior House Officer in Medical Rotation. Calderdale Healthcare, HALIFAX. HX3 0PW
  • Feb 93-Aug 93 Medical HO: Dumfries and Galloway Royal Infirmary, DUMFRIES
  • Aug 92-Feb 93 Surgical HO: Western General Hospital, EDINBURGH

Academic Background

  • 2000 MD University of Edinburgh
  • March 1995 MRCP (UK)
  • July 1992 MB ChB, University of Edinburgh

Key Research Interests

My main research interests include assessment of upper and lower airway function and disease activity using physiological assessment and surrogate measures of airway inflammation including bronchial and nasal challenge testing, induced sputum examination, nasal lavage and epithelial sampling and exhaled gas analysis. I have an interest in the pharmacological, nutritional and environmental effects on respiratory airways disease including asthma, rhinitis, emphysema and chronic bronchitis. Other research interests include the effect of matrix metalloproteases on airway remodelling and the delivery of drugs to the airways.


Research Group Members

Biomedicine, MED


Teaching Interests

I have an interest in the delivery of clinical teaching to undergraduate and post-graduate students especially in the areas of Respiratory Medicine and General Medicine. In particular I have an interest in alternative, non-lecture based, teaching methods for undergraduate students. Teaching activities include:

· Respiratory Unit Team Leader

· PBL Tutor

· Personal Advisor

· Lecturer and Seminar Leader in Respiratory Medicine and Clinical Pharmacology

· Student Research Project Supervisor

· Academic F2 programme leader


Number of items: 79.

Article

Smith, J, Noble, M, Musgrave, S, Murdoch, J, Price, G, Barton, GR, Windley, J, Holland, R, Harrison, B, Howe, A, Price, D, Harvey, I and Wilson, A (2012) The at-risk registers in severe asthma (ARRISA) study: a cluster-randomised controlled trial examining effectiveness and costs in primary care. Thorax. ISSN 0040-6376 (In Press)

Ramsay, C, Pearson, D, Mildenhall, M and Wilson, AM (2011) Oral Montelukast in Acute Asthma Exacerbations; a Randomised, Double-Blind, Placebo-Controlled Trial. Thorax, 66 (1). pp. 7-11.

Ampikaipakan, S, Hughes, DA, Hughes, JC, Amen, T, Bentham, G and Wilson, AM (2010) Vitamin D and COPD: seasonal variation is important. Thorax, Epub ahead of print.

Devereux, G., Wilson, Andrew, Avenell, A., McNeill, G. and Fraser, WD (2010) A case-control study of vitamin D status and asthma in adults. Allergy, 65 (5). pp. 666-667. ISSN 01054538

Yanny, S, Toms, A, MacIver, D, Barker, T and Wilson, AM (2010) Axial osseous sarcoidosis: rare clinical presentation and radiological findings. Clinical Radiology, 65 (2). pp. 167-171.

Ampikaipakan, S, Wilson, AM and Steel, N (2009) Complementary therapies for smoking cessation - a useful tool or merely a smoke screen? European Respiratory Disease, 5 (1). pp. 41-44.

Duong, M, Wilson, AM, Jayaram, L, Dolovich, M and Hargreave, F (2008) The effect of inhaled lidocaine-hydrofluoroalkane 134a in prednisone-dependent eosinphilic bronchitis. European Respiratory Journal, 32 (4). pp. 1119-22.

Wilson, AM, Aziz, I and Lipworth, BJ (2008) Effects of once-daily formoterol and budesonide given alone or in combination on surrogate inflammatory markers in asthmatic adults. Chest, 118. pp. 1049-1058.

Wilson, AM, Cooper, NJ, Thalanany, MM, Clemens, F, Hardy, P, Hibbert, C, Tiruvoipati, R, Truesdale, A, Robinson, S, Elbourne, DR, Peek, GJ and Mugford, M (2008) Methods of data collection and analysis for the economic evaluation alongside a national, multi-centre trial in the UK: conventional ventilation or ECMO for Severe Adult Respiratory Failure (CESAR). BMC Health Services Research, 8 (94).

Barnes, ML, Menzies, D, Fardon, TC, Burns, PJ, Wilson, AM and Lipworth, BJ (2007) Combined mediator blockade or topical steroid for treating the unified allergic airway. Allergy, 62 (1). pp. 73-80.

Wilson, AM (2006) The role of antihistamines in asthma management. Treatments in Respiratory Medicine, 5 (3). pp. 149-158.

Wilson, AM, Duong, M, Pratt, B, Dolovich, M and O'Byrne, P (2006) An assessment of the Anti-inflammatory Properties of once daily low dose inhaled Ciclesonide in Asthmatic Patients. Allergy, 61 (5). pp. 537-542.

Wilson, AM, Gray, RD, Hall, IP and Lipworth, BJ (2006) The effect of beta2-adrenoceptor haplotypes on bronchial hyper-responsiveness in patients with asthma. Allergy, 61 (2). pp. 254-259.

Wilson, AM, Leigh, R, Hargreave, F and Pizzichini, E (2006) An assessment of the safety of sputum induction in 100 consecutive patients with moderate to severe chronic airflow limitation. COPD, 3 (2). pp. 89-93.

Currie, GP, Lee, DK and Wilson, AM (2005) Effects of dual therapy with corticosteroids plus long acting beta2-agonists in asthma. Respiratory Medicine, 99 (6). pp. 683-694.

Wilson, AM, Duong, M, Crawford, L and Denburg, J (2005) An evaluation of peripheral blood eosinophil/basophil progenitors following nasal allergen challenge in patients with allergic rhinitis. Clinical and Experimental Allergy, 35 (1). pp. 39-44.

Hay, AD, Peters, MJ, Wilson, A and Fahey, T (2004) The use of infrared thermometry for the detection of fever. British Journal of General Practice (BJGP), 54 (503). pp. 448-450. ISSN 0960-1643

Hay, Alastair D, Fahey, Tom, Peters, Tim J and Wilson, Andrew (2004) Predicting complications from acute cough in pre-school children in primary care: a prospective cohort study. The British journal of general practice : the journal of the Royal College of General Practitioners, 54 (498). pp. 9-14. ISSN 0960-1643

Lee, DK, Gray, RD, Wilson, AM, Robb, FM, Soutar, PC and Lipworth, BJ (2004) Single and short-term dosing effects of levocetirizine on adenosine monophosphate bronchoprovocation in atopic asthma. British Journal of Clinical Pharmacology, 58 (1). pp. 34-39.

Wilson, AM, O'Byrne, PM and Parameswaran, K (2004) Leukotriene receptor antagonists for allergic rhinitis: a systematic review and meta-analysis. American Journal of Medicine, 116 (5). pp. 338-344.

Wilson, AM, Potter, JF, Taub, N, Moore, A and Robinson, T (2004) The effectiveness of a modified version of the Wilkinson questionnaire in screening for TIA and minor stroke in the United Kingdom. Age and Ageing, 34 (1). pp. 30-35.

Hay, A. D, Wilson, A, Fahey, T and Peters, TJ (2003) The duration of acute cough in pre-school children presenting to primary care: a prospective cohort study. Family Practice, 20 (6). pp. 696-705. ISSN 1460-2229

Currie, GP, Haggart, K, Lee, DK, Fowler, SJ, Wilson, AM, Brannan, JD, Anderson, SD and Lipworth, BJ (2003) Effects of histamine and leukotriene antagonism on mannitol and adenosine monophosphate challenges. Clinical and Experimental Allergy, 33 (6). pp. 783-788.

Wilson, AM, Coutie, WJ, Sims, EJ and Lipworth, BJ (2003) The skin vasoconstrictor assay does not correlate significantly to airway or systemic responsiveness to inhaled budesonide in asthmatic patients. European Journal of Clinical Pharmacology, 58 (10). pp. 643-647.

Wilson, AM, Orr, LC, Robb, F, Sims, EJ and Lipworth, BJ (2003) Reproducibilty of nasal function measurements with histamine and adenosine monophosphate nasal challenge testing in patients with allergic rhinitis. Allergology International, 52 (3). pp. 155-160.

Wilson, AM, Sims, EJ, Orr, LC, Robb, F and Lipworth, BJ (2003) An evaluation of short-term corticosteroid response in perennial allergic rhinitis using histamine and adenosine monophosphate nasal challenge. British Journal of Clinical Pharmacology, 55 (4). pp. 354-359.

Wilson, AM, Sims, EJ, Robb, F, Cockburn, W and Lipworth, BJ (2003) Peak inspiratory flow rate is more sensitive than acoustic rhinometry or rhinomanometry in detecting corticosteroid response with nasal histamine challenge. Rhinology, 41 (1). pp. 16-20.

Wilson, AM, Thabane, L and Holbrook, AE (2003) Application of data mining techniques in pharmacovigilance. British Journal of Clinical Pharmacology, 57 (2). pp. 127-134.

Currie, GP, Fowler, SJ, Wilson, AM, Sims, EJ, Orr, LC and Lipworth, BJ (2002) Airway and systemic effects of hydrofluoroalkane fluticasone and beclomethasone in patients with asthma. Thorax, 57 (10). pp. 865-868.

Dempsey, OJ, Fowler, SJ, Wilson, AM, Kennedy, G and Lipworth, BJ (2002) Effects of adding either a leukotriene receptor antagonist or low-dose theophylline to a low or medium dose of inhaled corticosteroid in patients with persistent asthma. Chest, 122 (1). pp. 151-159.

Fowler, SJ, Hall, IP, Wilson, AM, Wheatley, AP, Lipworth, BJ, Heeren, G and Marcerano, M (2002) 5-Lipoxygenase polymorphism and in-vivo response to leukotriene receptor antagonists. European Journal of Clinical Pharmacology, 58 (3). pp. 187-190.

Fowler, SJ, Orr, LC, Sims, EJ, Wilson, AM, Currie, GP, McFarlane, LC and Lipworth, BJ (2002) Therapeutic ratio of hydrofluroalkane and chlorofluorocarbon formulations of fluticasone propionate. Chest, 58. pp. 187-190.

Sims, EJ, Wilson, AM, White, PS, Gardiner, Q and Lipworth, BJ (2002) Short-term repeatability and correlates of laboratory measures of nasal function in patients with seasonal allergic rhinitis. Rhinology, 40 (2). pp. 66-68.

Wilson, AM (2002) Are antihistamines useful in managing asthma? Current Opinion Allergy Clin Immunol, 2 (1). pp. 53-59.

Wilson, AM (2002) Antihistamines alone and in combination with leukotriene antagonists in nasal congestion. Clinical and Experimental Allergy Reviews, 2 (1). pp. 1-6.

Wilson, AM, Haggart, K, Sims, EJ and Lipworth, BJ (2002) Effects of fexofenadine and desloratadine on subjective and objective measures of nasal congestion in seasonal allergic rhinitis. Clinical and Experimental Allergy, 32 (10). pp. 1504-1509.

Wilson, AM, Orr, LC, Coutie, WJ, Sims, EJ and Lipworth, BJ (2002) A comparison of once daily fexofenadine versus the combination of montelukast plus loratadine on domiciliary nasal peak flow and symptoms in seasonal allergic rhinitis. Clinical and Experimental Allergy, 32 (1). pp. 126-132.

Fowler, SJ, Orr, LC, Wilson, AM, Sims, EJ and Lipworth, BJ (2001) Dose-response for adrenal suppression with hydrofluoroalkane formulations of fluticasone propionate and beclomethasone dipropionate. British Journal of Clinical Pharmacology, 52. pp. 93-95.

Fowler, SJ, Wilson, AM, Griffiths, EA and Lipworth, BJ (2001) Comparative in vivo lung delivery of hydrofluoroalkane-salbutamol formulation via metered dose inhaler alone, plastic spacer or cardboard tube. Chest, 119. pp. 1018-1020.

Fowler, SJ, Wilson, AM, Martin, SW, White, PS, Gardiner, Q and Lipworth, BJ (2001) Evaluation of the importance of head and probe stabilisation in acoustic rhinometry. Rhinology, 39. pp. 93-97.

Nassif, R, Wilson, AM, White, PS, Gardiner, Q and Lipworth, BJ (2001) Effects of leukotriene receptor antagonist therapy in patients with severe rhinitis in a real life clinical setting. Rhinology, 38. pp. 142-146.

Wilson, AM, Dempsey, OJ, Sims, EJ and Lipworth, BJ (2001) Evaluation of salmeterol or montelukast as second-line therapy for asthma not controlled with inhaled corticosteroids. Chest, 119 (4). pp. 1021-1026.

Wilson, AM, Dempsey, OJ, Sims, EJ and Lipworth, BJ (2001) A comparison of topical budesonide and oral montelukast in seasonal allergic rhinitis and asthma. Clinical and Experimental Allergy, 31 (4). pp. 616-624.

Wilson, AM, Orr, LC, Sims, EJ and Lipworth, BJ (2001) Effects of monotherapy with intra-nasal corticosteroid or combines oral histamine and leukotriene receptor antagonists in seasonal allergic rhinitis. Clinical and Experimental Allergy, 31. pp. 61-68.

Wilson, AM, Sims, EJ, Orr, LC, Coutie, WJ, White, PS, Gardiner, Q and Lipworth, BJ (2001) Effects of topical corticosteroid and combined mediator blockade on domiciliary and laboratory measurements of nasal function in seasonal allergic rhinitis. Ann Allergy Asthma Immunol, 87. pp. 344-349.

Wilson, AM, Dempsey, OJ, Sims, EJ, Coutie, WJ, Paterson, M and Lipworth, BJ (2000) Evaluation of treatment response in patients with seasonal allergic rhinitis using domiciliary nasal peak inspiratory flow. Clinical and Experimental Allergy, 30 (6). pp. 833-838.

Wilson, AM, Dempsey, OJ, Sims, EJ and Lipworth, BJ (2000) Subjective and objective markers of treatment response in patients with seasonal allergic rhinitis. Ann Allergy Asthma Immunol, 85. pp. 111-114.

Wilson, AM, Dempsey, OJ, Sims, EJ, Mistry, C and Lipworth, BJ (2000) Addictive bronchoprotection and bronchodilator effects with single doses of salmeterol and montelukast in asthmatic patients receiving inhaled corticosteroids. Chest, 117. pp. 950-953.

Wilson, AM and Lipworth, BJ (2000) Does response evaluation of the therapeutic index for inhaled corticosteroid therapy in asthmatic patients. American Journal of Medicine, 111708. pp. 269-275.

Wilson, AM, Lipworth, BJ, Dempsey, OJ and Aziz, I (2000) Effects of adding in a leukotriene antagonist or a long acting B2-agonist in asthmatic patients possessing the glycine-16 B2-adrenoceptor genotype. American Journal of Medicine, 109 (2). pp. 114-121.

Wilson, AM, Nikander, K and Brown, PH (2000) Drug device matching. European Respiratory Review, 10. pp. 558-566.

Wilson, AM, Orr, LC, Sims, EJ, Dempsey, OJ and Lipworth, BJ (2000) Anti-asthmatic effects of mediator blockade versus topical corticosteroids in allergic rhinitis and asthma. American Jornal of Respiratory and Critical Care Medicine, 162. pp. 1297-1301.

Wilson, AM, Coutie, WJ, Dempsey, OJ, Williams, P and Lipworth, BJ (1999) Evaluation of the buccal componet of systemic absorption with inhaled fluticasone propionate. Thorax, 54 (7). pp. 614-617.

Wilson, AM, Dempsey, OJ, Coutie, WJ and Lipworth, BJ (1999) Evaluation of the effects of a large volume spacer on the systemic bioactivity of fluticasone propionate metered dose inhaler. Chest, 116. pp. 935-940.

Wilson, AM, Dempsey, OJ, Coutie, WJ, Sims, EJ and Lipworth, BJ (1999) Importance of drug-device interaction in determining systemic effects of inhales corticosteroids. Lancet, 353 (9170). p. 2128.

Wilson, AM, Macfarlane, A and Lipworth, BJ (1999) 24 Hour profiles of adrenocortical activity in asthmatic patients receiving inhaled and intra-nasal corticosteroid. Thorax, 54. pp. 20-27.

Wilson, AM, McFarlane, LC and Lipworth, BJ (1999) Short-term dose-response relationships for relative systemic effects of oral prednisolone and inhaled fluticasone in asthmatic adults. British Journal of Clinical Pharmacology, 48 (4). pp. 579-585.

Wilson, AM, Sims, EJ and Lipworth, BJ (1999) Does a response with fluticasasone propionate on adrenocortical activity and recovery of basal and stimulated responses after stopping treatment. Cleveland Clinic Journal of Medicine, 50. pp. 329-335.

Wilson, AM, Sims, EJ and Lipworth, BJ (1999) Does response with fluticasone propionate on adrenocortical activity and recovery of basal and stimulated responses after stopping treatment. Clinical Endocrinology, 50. p. 329.

Wilson, AM, Sims, J, Orr, LC and Lipworth, BJ (1999) Differences in lung bioavailability between HFA and CFC formulations of fluticasone propionate. Lancet, 354 (9187). pp. 1357-1358.

Wilson, AM, Brewster, HJA and Lipworth, BJ (1998) Dose response comparison os systemic bioactivity with inhaled budesonide and triamcinolone acetonide in asthmatice adults. Journal of Allergy and Clinical Immunology, 102 (5). pp. 751-760.

Wilson, AM, Clark, DJ, McFarlane, LC, Devlin, M and Lipworth, BJ (1998) Adrenocortical activity with repeated administration of once daily inhaled fluticasone propionate and budesonide in asthmatice adults. European Journal of Clinical Pharmacology, 53 (5). pp. 317-320.

Wilson, AM and Lipworth, BJ (1998) Does response to inhaled corticosteroid: benefits and risks. Seminars in Respiratory and Critical Care Medicine, 19 (6). pp. 625-642.

Wilson, AM, Lipworth, BJ and McFarlane, LC (1998) Systemic bioactivity profiles of oral prednisolone and nebulised budesonide in adult asthmatics. Chest, 114. pp. 1022-1027.

Wilson, AM, McFarlane, LC and Lipworth, BJ (1998) Effects of low and high doses of inhaled flunisolide and triamcinolone acetonide on basal and dynamic measures of HPA-axis activity in healthy volunteers. Journal of Clinical Endocrinology and Metabolism, 83 (3). pp. 922-925.

Wilson, AM, McFarlane, LC and Lipworth, BJ (1998) Effects of repeated once daily dosing of three intra-nasal corticosteroids in basal and dynamic measures of HPS-axis activity. Journal of Allergy and Clinical Immunology, 101 (4). pp. 470-474.

Wilson, AM, McFarlane, LC and Lipworth, BJ (1998) Effects of intra-nasal corticosteroids on adrenal,bone and blood markers of systemic activity in allergic rhinitis. Journal of Allergy and Clinical Immunology, 102 (4). pp. 598-604.

Wilson, AM, Sims, EJ, Struthers, AD and Lipworth, BJ (1998) Inhaled corticosteroid therapy reduces early morning peak in cortisol and aldosterone. Clinical Science, 95. pp. 513-517.

Wilson, AM, McFarlane, LC and Lipworth, BJ (1997) Dose response effect for adrenal suppression with repeated twice daily inhaled fluticasone propionate and triamcinolone acetonide in adult asthmatics. American Jornal of Respiratory and Critical Care Medicine, 156. pp. 1274-1277.

Monograph

Hay, AD, Peters, TJ, Wilson, A and Fahey, T (2004) Infrared ear thermometry - Reply. Letter. ROYAL COLL GENERAL PRACTITIONERS, 14 PRINCES GATE, HYDE PARK, LONDON SW7 1PU, ENGLAND , BRITISH JOURNAL OF GENERAL PRACTICE, Volume 54, Issue 508, Pages 869-869.

Hay, AD, Peters, TJ, Fahey, T and Wilson, A (2004) Complications defining 'complications' - Authors response. Letter. ROYAL COLL GENERAL PRACTITIONERS, 14 PRINCES GATE, HYDE PARK, LONDON SW7 1PU, ENGLAND , BRITISH JOURNAL OF GENERAL PRACTICE, Volume 54, Issue 501, Pages 300-300.

Currie, GP, Fowler, S, Wilson, A, Sims, EJ, Orr, L and Lipworth, BJ (2002) Airway-systemic ratio of hydrofluoroalkane fluticasone and beclomethasone in asthmatics. Meeting Abstract. MOSBY, INC, 11830 WESTLINE INDUSTRIAL DR, ST LOUIS, MO 63146-3318 USA , JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, Volume 109, Issue 1, Pages S252-S252.

Conference or Workshop Item

Smith, J. R., Noble, M. J., Musgrave, S. D., Murdoch, J., Price, G, Martin, A., Windley, J., Holland, R., Harrison, B. D. W., Price, D., Howe, A., Harvey, I. and Wilson, A. M. (2010) S137 The At-Risk Registers in Severe Asthma (ARRISA) Study: a cluster-randomised controlled trial in primary care. In: British Thoracic Society, December 2010, London.

Wilson, AM (2004) Its not the inhaler it's what you do with it. In: Breathing Club, Chantilly, Paris.

Wilson, AM (2003) Objective measurement of airways inflammation. In: The Scientific meeting of the Association of Allergists and Clinical Immunologists of Quebec, Quebec.

Wilson, AM (2003) Are Antihistamines Useful in Managing Asthma? In: World Allergy Organisation Congress, Vancouver, Canada.

Wilson, AM (2002) Antihistamine Therapy and Asthma. In: Launch Conference for Levocetirizine, Cannes, France.

Wilson, AM (2001) Antihistamines alone and in combination with leukotriene antagonists in nasal congestion. In: European Academy of Allergology and Clinical Immunology, Berlin.

Wilson, AM (2001) A Therapeutic Update in COPD and Asthma. In: Scottish Centre for Post Qualification Pharmaceutical Education, Stirling, UK.

This list was generated on Fri Apr 5 19:20:25 2013 BST.

External Activities and Indicators of Esteem

  • Scadding-Morriston Davies Fellow 2002-2003
  • Finalist of the Schering Plough International Young Researcher 2000. Rome, Italy 29 October 1999
  • Winner of the Fitzgerald-Peel Prize, Scottish Society of Physicians, Glasgow, October 2000

Professional Activities

  • Member of the working committee organised by the European Respiratory Society to produce guidelines for the use of nebulisers in Respiratory Medicine. (Eur Respir J 2001;18:228-242). Attended symposium to discuss my paper on “Drug Device Matching” at Weisbaden, Germany, 29 September 1999 to 1 October 1999
  • Member of expert panel to attended a Phase II conference on “Allergic rhinits a burden to both the patient and NHS” BMA House, London, UK, 4 February 2000
  • Invited to attend a “Dry Powder Inhaler Advisory Board” in New York 27-28 July 2000 to help with the launch of Asmanex, Key Pharmaceuticals, USA

Administrative Posts/Responsibilities

  • MBBS Unit 5 (Respiratory) Team Leader
  • Academic F2 Co-ordinator
  • Clinical Research and Trials Unit team member
  • MBBS Curriculum Development team member
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