Article

Kay, CD, Hooper, L, Kroon, PA, Rimm, EB and Cassidy, A (2012) Relative impact of flavonoid composition, dose and structure on vascular function: A systematic review of randomised controlled trials of flavonoid-rich food products. Molecular Nutrition & Food Research, 56 (11). pp. 1605-1616. ISSN 16134125

Welch, A, Macgregor, A, Jennings, A, Fairweather-Tait, S, Spector, T and Cassidy, A (2012) Habitual flavonoid intakes are positively associated with bone mineral density in women. Journal of Bone and Mineral Research, 27 (9). pp. 1872-1878. ISSN 08840431

Jennings, A, Welch, A, Fairweather-Tait, SJ, Kay, C, Minihane, A-M, Chowienczyk, P, Jiang, B, Cecelja, M, Spector, T, Macgregor, A and Cassidy, A (2012) Higher anthocyanin intake is associated with lower arterial stiffness and central pressure in women. The American Journal of Clinical Nutrition. ISSN 0002-9165

Cassidy, A, Rimm, EB, O'Reilly, E, Logroscino, C, Kay, C, Chiuve, SE and Rexrode, KM (2012) Dietary Flavonoids and Risk of Stroke in Women. Stroke. ISSN 0039-2499 (In Press)

Hooper, L, Kay, CD, Abdelhamid, A, Kroon, PA, Cohn, JS, Rimm, EB and Cassidy, A (2012) Effects of chocolate, cocoa, and flavan-3-ols on cardiovascular health: a systematic review and meta-analysis of randomized trials. American Journal of Clinical Nutrition, 95 (3). pp. 740-751. ISSN 0002-9165

Curtis, P, Sampson, M, Potter, JF, Dhatariya, K, Kroon, PA and Cassidy, A (2012) Chronic ingestion of flavan-3-ols and isoflavones improves insulin sensitivity and lipoprotein status and attenuates estimated 10-year CVD risk in medicated postmenopausal women with type 2 diabetes: a one year double-blind randomized controlled trial. Diabetes Care, 35 (2). pp. 226-232. ISSN 0149-5992

Barrera, LN, Cassidy, A, Wei, T, Wang, W, Belshaw, N, Johnson, I, Brigelius-Flohe, R and Bao, Y (2012) TrxR1 and Gpx2 are potently induced by isothiocyanates and selenium, and mutually cooperate to protect Caco-2 cells against free radical-mediated cell death. BBA-Molecular Cell Research, 1823. pp. 1914-1924.

Barrera, LN, Johnson, IT, Bao, Y, Cassidy, A and Belshaw, N (2012) Colorectal cancer cells Caco-2 and HCT116 resist epigenetic effects of isothiocyanates and selenium in vitro. European Journal of Nutrition. (In Press)

Barrera , LN, Cassidy, A, Johnson, Ian T., Bao, Y and Belshaw, NJ (2012) Epigenetic and antioxidant effects of dietary isothiocyanates and selenium: potential implications for cancer chemoprevention. Proceedings of the Nutrition Society, 71. pp. 237-245. ISSN 0029-6651

Gao, X, Cassidy, A, Schwarzchild, M, Rimm, EB and Ascherio, A (2012) Habitual intake of dietary flavonoids and risk of Parkinson's disease. Neurology. (In Press)

Jennings, A, Cassidy, A, Winters, T, Barnes, S, Lipp, A, Holland, R and Welch, A (2012) A positive effect of a targeted community intervention to improve access and availability of fruit and vegetables in a deprived area. (In Press)

Jennings, A, Welch, A, van Sluijs, E, Griffin, S and Cassidy, A (2012) Associations between eating frequency, adiposity, diet and activity in healthy weight and centrally obese children 9-10 years. (In Press)

Vissers, P, Jones, A, van Sluijs, E, Jennings, A, Welch, A, Cassidy, A and Griffin, S (2012) The association between diet and physical activity and sedentary behaviours in 9-10 year old British children. Public Health Nutrition. (In Press)

Warwick, E, Cassidy, A, Hanley, B, Jouni, ZE and Bao, Y (2012) Effect of phytochemicals on phase II enzyme expression in infant human primary skin fibroblast cells. British Journal of Nutrition. pp. 1-8. ISSN 0007-1145

Fairweather-Tait, SJ, Skinner, J, Guile, G, Cassidy, A, Spector, TD and Macgregor, AJ (2011) Diet and bone mineral density study of twins shows a negative association with a traditional English dietary pattern and a positive association with alcohol. The American Journal of Clinical Nutrition, 94. pp. 1371-1375. ISSN 0002-9165

Harrison, F, Jennings, A, Jones, A, Welch, A, van Sluijs, E, Griffin, S and Cassidy, A (2011) Food and drink consumption at school lunchtime: The impact of lunch type and contribution to overall intake in British 9/10-yr old children. Public Health Nutrition. pp. 1-8.

Vissers, PA, Jones, AP, Corder, K, Jennings, A, van Sluijs, EM, Welch, A, Cassidy, A and Griffin, S (2011) Breakfast consumption and daily physical activity in 9–10-year-old British children. Public Health Nutrition, 7. pp. 1-10. ISSN 1368-9800

Zamora-Ros, R, Knaze, V, Lujan-Barroso, L, Slimani, N, Romieu, I, Fedirko, V, Santucci de Magistris, M, Ericson, U, Amiano, P, Trichopoulou, A, Dilis, V, Naska, A, Engeset, D, Skeie, G and Cassidy, A (2011) Estimated dietary intakes of flavonols, flavanones and flavones in the European Prospective Investigation into Cancer and Nutrition (EPIC) 24 hour dietary recall cohort. British Journal of Nutrition, 17. pp. 1-11.

Hollman, PCH, Cassidy, A, Comte, B, Heinonen, M, Richelle, M, Richling, E, Serafini, M, Scalbert, A, Sies, H and Vidry, S (2011) The Biological Relevance of Direct Antioxidant Effects of Polyphenols for Cardiovascular Health in Humans Is Not Established. Journal of Nutrition, 141 (5). 989S-1009S. ISSN 0022-3166

Jennings, A, Welch, A, Jones, AP, Harrison, F, Bentham, G, Van Sluijs, EMF, Griffin, SJ and Cassidy, A (2011) Local food outlets, weight status, and dietary intake: associations in children aged 9-10 years. American Journal of Preventive Medicine, 40 (4). pp. 405-410.

Landberg, R, Sun, Q, Rimm, EB, Cassidy, A, Scalbert, A, Mantzoros, CS, Hu, FB and van Dam, RM (2011) Selected dietary flavonoids are associated with markers of inflammation and endothelial dysfunction in US women. The Journal of Nutrition, 141 (4). pp. 618-625. ISSN 0022-3166

Cassidy, A., O'Reilly, E. J., Kay, C., Sampson, L., Franz, M., Forman, J., Curhan, G. and Rimm, E. B. (2011) Habitual intake of flavonoid subclasses and incident hypertension in adults. American Journal of Clinical Nutrition, 93 (2). pp. 338-347. ISSN 0002-9165

Jennings, A, Welch, A, van Sluijs, EM, Griffin, SJ and Cassidy, A (2011) Diet quality is independently associated with weight status in children aged 9-10 years. The Journal of Nutrition, 141 (3). pp. 453-459. ISSN 0022-3166

Harrison, F, Bentham, G, Jones, AP, Cassidy, A, van Sluijs, EMF and Griffin, SJ (2011) School level correlates with adiposity in 9–10 year old children. Health & Place, 17 (3). pp. 710-716. ISSN 13538292

Harrison, F, Jones, AP, Bentham, G, van Sluijs, EMF, Cassidy, A and Griffin, SJ (2011) The impact of rainfall and school break time policies on physical activity in 9-10 year old British children: A repeated measures study. International Journal of Behavioral Nutrition and Physical Activity, 8 (1). p. 47. ISSN 1479-5868

Harrison, F, Jones, AP, van Sluijs, EMF, Cassidy, A, Bentham, G and Griffin, SJ (2011) Environmental correlates of adiposity in 9–10 year old children: Considering home and school neighbourhoods and routes to school. Social Science & Medicine, 72 (9). pp. 1411-1419. ISSN 02779536

Hooper, L, Madhavan, G, Tice, J, Leinster, SJ and Cassidy, A (2010) Effects of isoflavones on breast density in pre- and post- menopausal women: a systematic review and meta-analysis of randomised controlled trials. Human Reproduction Update, 16 (6). pp. 745-60.

Perez-Jimenez, J., Hubert, J., Hooper, L., Cassidy, A, Manach, C., Williamson, G. and Scalbert, A. (2010) Urinary metabolites as biomarkers of polyphenol intake in humans: a systematic review. American Journal of Clinical Nutrition, 92 (4). pp. 801-809. ISSN 0002-9165

Cassidy, A, De Vivo, I, Liu, Y, Han, J, Prescott, J, Hunter, DJ and Rimm, EB (2010) Associations between diet, lifestyle factors, and telomere length in women. American Journal of Clinical Nutrition, 91 (5). pp. 1273-1280.

Corder, K, van Sluijs, EMF, McMinn, AM, Ekelund, U, Cassidy, A and Griffin, SJ (2010) Perception versus reality awareness of physical activity levels of british children. American Journal Prev Med, 38 (1). pp. 1-8.

Skidmore, P, Welch, A, Van Sluijs, E, Jones, A, Harvey, I, Harrison, F, Griffin, S and Cassidy, A (2010) Impact of neighbourhood food environment on food consumption in children aged 9-10 years in the UK SPEEDY (Sport, Physical Activity and Eating behaviour: Environmental Determinants in Young people) study. Public Health Nutrition, 13 (7). pp. 1022-1030.

Cassidy, A, Skidmore, PML, Rimm, E, Welch, AA, Fairweather-Tait, SJ, Skinner, J, Burling, K, Richards, J, Spector, TD and MacGregor, AJ (2009) Plasma adiponectin concentrations are associated with body composition and plant based dietary factors in female twins. Journal of Nutrition, 139 (2). pp. 353-358.

Cassidy, A, Chiuve, S, Manson, J, Rexrode, K, Girman, C and Rimm, E (2009) Potential role for plasma placental growth factor in predicting coronary heart disease risk in women. ATVB, 29 (1). pp. 134-139.

Curtis, P, Kroon, PA, Hollands, WJ, Walls, R, Jenkins, G, Kay, CD and Cassidy, A (2009) Cardiovascular disease risk biomarkers and liver and kidney function are not altered in postmenopausal women after ingesting an Elderberry Extract Rich in Anthocyanins for twelve weeks. Journal of Nutrition, 139 (12). pp. 2266-2271.

Hooper, L, Ryder, JJ, Kurzer, MS, Lampe, JW, Messina, MJ, Phipps, WR and Cassidy, A (2009) Effects of soy protein and isoflavones on circulating hormone concentrations in pre- and postmenopausal women: a systematic review and meta-analysis. Human Reproduction Update, 15 (4). pp. 423-440.

Kay, CD, Kroon, PA and Cassidy, A (2009) The bioactivity of dietary anthocyanins is likely to be mediated by their degradation products. Molecular Nutrition & Food Research, 53 (Suppl 1). S92-101.

Mortenson, A, Kulling, SE, Schwartz, H, Rowland, I, Ruefer, CE, Rimbach, G, Cassidy, A, Magee, P, Millar, J, Hall, WL, Kramer Berkved, F, Sorensen, IK and Sontag, G (2009) Analytical and compositional aspects of isoflavones in food and their biological effects. Molecular Nutrition & Food Research, 53 (Suppl 2). S266-309.

Shan, Y, Wu, K, Wang, W, Wang, S, Lin, N, Zhao, R, Cassidy, A and Bao, Y (2009) Sulforaphane down-regulates COX-2 expression by activating p38 and inhibiting NF-kappaB-DNA-binding activity in human bladder T24 cells. International Journal of Oncology, 34 (4). pp. 1129-1134.

Skidmore, PML, Cassidy, A, Swaminathan, R, Richards, J, Mangino, M, Spector, TD and MacGregor, AJ (2009) An obesogenic postnatal environment is more important than the fetal environment for development of adult adiposity: a study of female twins. American Journal of Clinical Nutrition, 90 (2). pp. 401-406.

Steele, RM, van Sluijs, EMF, Cassidy, A, Griffin, SJ and Ekelund, U (2009) Targeting sedentary time or moderate- and vigorous-intensity activity: independent relations with adiposity in a population-based sample of 10-y-old British children. American Journal of Clinical Nutrition, 90 (5). pp. 1185-1192.

Woodward, G, Kroon, PA, Cassidy, A and Kay, CD (2009) Anthocyanin stability and recovery: implications for the analysis of clinical and experimental samples. Journal of Agricultural and Food Chemistry, 57 (12). pp. 5271-5278.

Ranka, S, Gee, JM, Biro, L, Brett, G, Saha, S, Kroon, PA, Skinner, J, Hart, AR, Cassidy, A, Rhodes, M and Johnson, IT (2008) Development of a food frequency questionnaire for the assessment of quercetin and naringenin intake. European Journal of Clinical Nutrition, 62 (9). pp. 1131-8.

Brink, E, Coxam, V, Robins, SP, Wahala, K, Cassidy, A and Branca, F (2008) Long-term consumption of isoflavone-enriched foods does not affect bone mineral density, bone metabolism and hormonal status in early post-menopausal women: a randomised double-blind, placebo controlled study. American Journal of Clinical Nutrition, 87 (3). pp. 761-770.

Hooper, L, Kroon, PA, Rimm, EB, Cohn, JS, Harvey, IM, Le Cornu, KA, Ryder, JJ, Hall, WL and Cassidy, A (2008) Flavonoids, flavonoid-rich foods and cardiovascular risk: a meta-analysis of randomized controlled trials. American Journal of Clinical Nutrition, 88 (1). pp. 38-50.

Mastrangelo, L, Cassidy, A, Mulholland, F, Wang, W and Bao, Y (2008) Serotonin Receptors, Novel Targets of Sulforaphane Identified by Proteomic Analysis in Caco-2 Cells. Cancer Research, 68 (13). pp. 5487-5491.

Skidmore, PML, Cassidy, A, Swaminathan, R, Richards, J, Spector, TD and MacGregor, AJ (2008) Relation of birth weight, BMI and change in size from birth to adulthood to insulin resistance in a female twin cohort. Journal of Endocrinol Metab, 93 (2). pp. 516-520.

van Sluijs, EMF, Skidmore, PML, Mwanza, K, Jones, AP, Callaghan, AM, Ekelund, U, Harrison, F, Harvey, IM, Panter, J, Wareham, NJ, Cassidy, A and Griffin, SJ (2008) Physical activity and dietary behaviour in a population based sample of British 10-year old children: the SPEEDY study (Sport, Physical activity and Eating behaviour: Environmental Determinants in Young people). BMC Public Health, 8 (1). p. 388.

Talbot, DC, Ogborne, RM, Dadd, T, Adlercreutz, H, Barnard, G, Bugel, S, Kohen, F, Marlin, S, Piron, J, Cassidy, A and Powell, J (2007) Monoclonal Antibody-Based Time-Resolved Fluorescence Immunoassays for Daidzein, Genistein, and Equol in Blood and Urine: Application to the Isoheart Intervention Study. Clinical Chemistry, 53 (4). pp. 748-756.

Teucher, B, Skinner, J, Skidmore, PML, Cassidy, A, Fairweather-Tait, S, Hooper, L, Roe, MA, Foxall, R, Oyston, SL, Cherkas, LF, Perks, UC, Spector, TD and MacGregor, AJ (2007) Dietary patterns and heritability of food choice in a UK female twin cohort. Twin Research and Human Genetics, 10 (5). pp. 734-748.

Cassidy, A (2006) Factors affecting the bioavailability of soy isoflavones in humans. J AOAC, 89 (4). pp. 1182-1188.

Cassidy, A, Albertazzi, P, Lise Nielsen, I, Hall, W, Williamson, G, Tetens, I, Atkins, S, Cross, H, Manios, Y, Wolk, A, Steiner, C and Branca, F (2006) Critical review of health effects of soyabean phyto-oestrogens in post-menopausal women. Proceedings of Nutrition Society, 65 (1a). pp. 76-92.

Cassidy, A, Brown, JE, Hawdon, A, Faughnan, MS, King, LJ, Millward, J, Zimmer-Nechemias, L, Wolfe, B and Setchell, KD (2006) Factors affecting the bioavailability of soy isoflavones in humans after ingestion of physiologically relevant levels from different soy foods. Journal of Nutrition, 136 (1). pp. 45-51.

Cassidy, A and Hooper, L (2006) Phytoestrogens and cardiovascular disease. Journal of British Menopause Society, 12 (2). pp. 49-56.

De Pascual-Teresa, S, Hallund, J, Talbot, D, Schroot, J, Williams, CM, Bugel, S and Cassidy, A (2006) Absorption of isoflavones in humans: effects of food matrix and processing. Nutritional Biochemistry, 17 (4). pp. 257-264.

Hall, WL, Vafeiadou, K, Hallund, J, Bugel, S, Reimann, M, Koebnick, C, Zunft, HJ, Ferrari, M, Branca, F, Dadd, T, Talbot, D, Powell, J, Minihane, AM, Cassidy, A, Nilsson, M, Dahlman-Wright, K, Gustafsson, JA and Williams, CM (2006) Soy-isoflavone-enriched foods and markers of lipid and glucose metabolism in postmenopausal women: interactions with genotype and equol production. American Journal of Clinical Nutrition, 83 (3). pp. 592-600.

Hooper, L and Cassidy, A (2006) A review of the health care potential of bioactive compounds. J Sci Food and Agric, 86 (12). p. 1805. ISSN 1813

Shan, Y, Sun, C, Zhao, X, Wu, K, Cassidy, A and Bao, Y (2006) Effect of sulforaphane on cell growth, G(0)/G(1) phase cell progression and apoptosis in human bladder cancer T24 cells. International Journal of Oncology, 29 (4). pp. 883-888.

Skidmore, PML, Cassidy, A, Swaminathan, R, Falchi, M, Spector, TD and MacGregor, AJ (2006) Intrauterine, Environmental, and Genetic Influences in the Relationship Between Birth Weight and Lipids in a Female Twin Cohort. Arterioscler Thromb Vasc Biol, 26 (10). pp. 2373-2379.

Bryant, M, Cassidy, A, Hill, C, Powell, J, Talbot, D and Dye, L (2005) Effect of consumption of soy isoflavones on behavioural, somatic and affective symptoms in women with Premenstrual Syndrome (PMS). British Journal of Nutrition, 93 (5). pp. 731-739.

Cassidy, A (2005) Dietary phytoestrogens - molecular mechanisms, bioavailability and importance to menopausal health. Nutrition Research Reviews, 18 (2). pp. 183-201.

Solanky, KS, Holmes, E, Davis, A, Bingham, SA, Nicholson, J and Cassidy, A (2005) 1H NMR based metabonomic techniques applied to nutrition research - metabolic effects of dietary isoflavones in humans. The Journal of Nutritional Biochemistry, 16 (4). pp. 236-244.

Totta, P, Acconcia, F, Virgili, F, Cassidy, A, Weinberg, PD, Rimbach, G and Marino, M (2005) Daidzein-sulfate metabolites affect transcriptional and antiproliferative activities of estrogen receptor-beta in cultured human cancer cells. Journal of Nutrition, 135 (11). pp. 2687-2693.

Faughnan, MS, Hawdon, A, Ah-Singh, E, Brown, J, Millward, DJ and Cassidy, A (2004) Urinary isoflavone kinetics: the effect of age, gender, food matrix and chemical composition. British Journal of Nutrition, 91 (4). pp. 567-574.

Rimbach, G, Weinberg, PD, De Pascual-Teresa, S, Alonso, MG, Ewins, BA, Turner, R, Minihane, AM, Botting, NP, Fairley, B, Matsugo, S, Uchida, Y and Cassidy, A (2004) Sulfation of genistein alters its antioxidant properties and its effect on platelet aggregation and monocyte and endothelial function. Biochimica et Biophysica Acta, 1670 (3). pp. 229-237.

Turner, R, Baron, T, Wolffram, S, Minihane, AM, Cassidy, A, Rimbach, G and Weinberg, PD (2004) Effect of circulating forms of soy isoflavones on the oxidation of low density lipoprotein. Free Radical Research, 38 (2). pp. 209-216.

Fairley, B, Botting, NP and Cassidy, A (2003) The synthesis of daidzein sulphates. Tetrahedron, 59 (29). pp. 5407-5410.

Burns, L, Ashwell, M, Berry, J, Bolton-Smith, C and Cassidy, A (2003) UK Food Standards Agency Optimal Nutrition Status Workshop: environmental factors that affect bone health throughout. British Journal of Nutrition, 89 (6). pp. 835-840.

Cassidy, A (2003) Are herbal remedies and dietary supplements safe and effective for breast cancer patients? Breast Cancer Research, 5 (6). pp. 300-302.

Cassidy, A (2003) Potential risks and benefits of phytoestrogen-rich diets. International Journal of Vitam Nutr Res, 73 (2). pp. 120-126.

Cassidy, A (2003) Phytoestrogens and Bone Health. Journal of British Menopause Society, 9 (1). pp. 17-21.

Cassidy, A (2003) Committee on Toxicity draft report on phyto-oestrogens and health - Review of proposed health effects of phyto-oestrogen exposure and recommendations for future research. Nutrition Bulletin, 28 (2). pp. 135-138.

Cassidy, A, De Pascual-Teresa, S and Rimbach, GH (2003) Molecular mechanisms by which isoflavones potentially prevent atherosclerosis. Expert Reviews in Molecular Medicine, 5. pp. 1-9.

Rowland, I, Faughnan, M, Hoey, L, Wahala, K, Williamson, G and Cassidy, A (2003) Bioavailability of Phyto-oestrogens. British Journal of Nutrition, 89 (Suppl 1). pp. 45-58.

Setchell, KDR, Faughnan, MS, Avades, T, Zimmer-Nechemias, L, Wolfe, B, Brashear, W, Desai, P, Oldfield, M, Botting, NP, Cassidy, A and Brown, NM (2003) Comparing the pharmacokinetics of daidzein and genistein with the use of 13C-labeled tracers in premenopausal women. American Journal of Clinical Nutrition, 77 (2). pp. 411-419.

Solanky, KS, Holmes, E, Davis, A, Bingham, SA, Bingham, S, Nicholson, JK, Cassidy, A, Bailey, NJC and Beckwith-Hall, BM (2003) Application of Biofluid ¹H nuclear magnetic resonance-based metabonomic techniques for the analysis of the biochemical effects of dietary isoflavones on human plasma profile. Analytical Biochemistry, 323 (2). pp. 197-204.

Valtuena, S, Cashman, K, Robins, SP, Cassidy, A, Kardinaal, A and Branca, F (2003) Investigating the role of natural phyto-oestrogens on bone health in postmenopausal women. British Journal of Nutrition, 89 (Suppl 1). pp. 87-99.

Setchell, KDR, Brown, NM, Desai, P, Zimmer-Nechemias, L, Wolfe, B, Brashear, W, Kirschner, AS, Cassidy, A and Heubi, JE (2001) Bioavailability of pure isoflavones in healthy humans and analysis of commercial soy isoflavone supplements. Journal of Nutrition, 131 (4). pp. 1362-1375.

Cassidy, A and Faughnan, M (2000) Phytoestrogens through the lifecycle. Proceedings of Nutrition Society, 59. pp. 489-496.

Cassidy, A, Hanley, B and Lamuela-Raventos, RM (2000) Isoflavones,Lignans and stilbenes - origins, metabolism and potential importance to human health. J Sci Food and Agric, 80 (7). pp. 1044-1062.