Biography

Cock van Oosterhout did his PhD on captive metapopulations of the butterfly Bicyclus anynana at Leiden University in the Netherlands under the supervision of Paul Brakefield.  He moved to the UK in 1998 where he worked on guppies (Poecilia reticulata) at the University of Hull.  He received an NERC Fellowship testing conservation genetic breeding protocols, reintroduction and genetic supplementation programs using guppies as an empirical model and did this research in Hull and Trinidad.  He developed software applications, including Micro-Checker for population genetic analysis of microsatellites, as well as models of host-parasite coevolution and population genetic simulations, and more recently, he designed software for whole genome analysis of recombination (Hybrid-Check). He works on a wide range of species, including guppies, cichlids, plant parasites (aphids and oomycetes), diatoms and the pink pigeon, and he is particularly interested in the evolution of immune and resistance genes, and effector genes. He is currently a Professor of Evolutionary Genetics at the University of East Anglia and acts as Deputy Director of the Earth and Life Systems Alliance (ELSA), collaborating with researchers across Norwich Research Park (NRP).

Academic Background

  • 2015-present: Professor of Evolutionary Genetics, UEA, UK
  • 2011-2015: Reader of Evolutionary Genetics, University of East Anglia (UEA), UK
  • 2007-2011: Lecturer, University of Hull, UK
  • 2003-2007: Senior Fellow, University of Hull, UK
  • 2001-2003: NERC Fellow, University of Hull, UK
  • 1998-2001: Post-doc, University of Hull, UK
  • 1992-2000: PhD Leiden University, the Netherlands
  • 1986-1991: BSc and MSc (Hons) Leiden University, the Netherlands  

PhD Positions

Click here for current PhD opportunities in the School of Environmental Sciences. But feel free to email me to discuss projects outside these areas and alternative sources of funding.

All Publications

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Bentkowski, P., Van Oosterhout, C., Ashby, B., Mock, T.

(2017)

The effect of extrinsic mortality on genome size evolution in prokaryotes,

in The ISME Journal

11

(4)

pp. 1011–1018

Full Text UEA Repository

(Article)

(Published)


Mock, T., Otillar, R. P., Strauss, J., McMullan, M., Paajanen, P., Schmutz, J., Salamov, A., Sanges, R., Toseland, A., Ward, B. J., Allen, A. E., Dupont, C. L., Frickenhaus, S., Maumus, F., Veluchamy, A., Wu, T., Barry, K. W., Falciatore, A., Ferrante, M. I., Fortunato, A. E., Glöckner, G., Gruber, A., Hipkin, R., Janech, M. G., Kroth, P. G., Leese, F., Lindquist, E. A., Lyon, B. R., Martin, J., Mayer, C., Parker, M., Quesneville, H., Raymond, J. A., Uhlig, C., Valas, R. E., Valentin, K. U., Worden, A. Z., Armbrust, E. V., Clark, M. D., Bowler, C., Green, B. R., Moulton, V., Van Oosterhout, C., Grigoriev, I. V.

(2017)

Evolutionary genomics of a cold-adapted diatom: Fragilariopsis cylindrus,

in Nature

541

pp. 536–540

Full Text UEA Repository

(Article)

(Published)


Mathers, T. C., Chen, Y., Kaithakottil, G., Legeai, F., Mugford, S. T., Baa-Puyoulet, P., Bretaudeau, A., Clavijo, B., Colella, S., Collin, O., Dalmay, T., Derrien, T., Feng, H., Gabaldón, T., Jordan, A., Julca, I., Kettles, G. J., Kowitwanich, K., Lavenier, D., Lenzi, P., Lopez-Gomollon, S., Loska, D., Mapleson, D., Maumus, F., Moxon, S., Price, D. R. G., Sugio, A., van Munster, M., Uzest, M., Waite, D., Jander, G., Tagu, D., Wilson, A. C. C., van Oosterhout, C., Swarbreck, D., Hogenhout, S. A.

(2017)

Rapid transcriptional plasticity of duplicated gene clusters enables a clonally reproducing aphid to colonise diverse plant species,

in Genome Biology

18

article no. 27

Full Text UEA Repository

(Article)

(Published)


Svensson, O., Woodhouse, K., Van Oosterhout, C., Smith, A., Turner, G. F., Seehausen, O.

(2017)

The genetics of mate preferences in hybrids between two young and sympatric Lake Victoria cichlid species,

in Proceedings of the Royal Society of London B

284

(1849)

article no. 284

pp. 233-243

Full Text UEA Repository

(Article)

(Published)


Lighten, J., van Oosterhout, C.

(2017)

Biocontrol of common carp in Australia poses risks to biosecurity,

in Nature Ecology & Evolution

1

article no. 0087

Full Text

(Comment/debate)

(Published)


Gilroy, D., Phillips, K., Richardson, D. S., Van Oosterhout, C.

(2017)

Toll-like receptor variation in the bottlenecked population of the Seychelles warbler: computer simulations see the ‘ghost of selection past’ and quantify the ‘drift debt’,

in Journal of Evolutionary Biology

Full Text UEA Repository

(Article)

(E-pub ahead of print)


Santonastaso, T., Lighten, J., van Oosterhout, C., Jones, K. L., Foufopoulos, J., Anthony, N. M.

(2017)

The effects of historical fragmentation on major histocompatibility complex class II β and microsatellite variation in the Aegean island reptile, Podarcis erhardii,

in Ecology and Evolution

Full Text UEA Repository

(Article)

(E-pub ahead of print)


Bolton, N. M., Van Oosterhout, C., Collar, N. J., Bell, D. J.

(2016)

Population constraints on the Grenada Dove Leptotila wellsi: preliminary findings and proposals from south-west Grenada,

in Bird Conservation International

26

(02)

pp. 205-213

Full Text UEA Repository

(Article)

(Published)


Ward, B. J., Van Oosterhout, C.

(2016)

HYBRIDCHECK: software for the rapid detection, visualization and dating of recombinant regions in genome sequence data,

in Molecular Ecology Resources

16

(2)

pp. 534–539

Full Text UEA Repository

(Article)

(Published)


Gilroy, D., Van Oosterhout, C., Komdeur, J., Richardson, D. S.

(2016)

Avian β-defensin variation in bottlenecked populations: the Seychelles warbler and other congeners,

in Conservation Genetics

17

(3)

pp. 661-674

Full Text UEA Repository

(Article)

(Published)


Stevenson, J. F., Kinsella, C., Cable, J., Van Oosterhout, C.

(2016)

A further cost for the sicker sex? Evidence for male-biased parasite-induced vulnerability to predation,

in Ecology and Evolution

6

(8)

pp. 2506–2515

Full Text UEA Repository

(Article)

(Published)


Svensson, O., Smith, A., Garcia-Alonso, J., Van Oosterhout, C.

(2016)

Hybridisation generates a hopeful monster: a hermaphroditic selfing cichlid,

in Royal Society Open Science

3

article no. 150684

Full Text UEA Repository

(Article)

(Published)


Mohammed, R. S., Reynolds, M., James, J., Williams, C., Mohammed, A., Ramsubhag, A., van Oosterhout, C., Cable, J.

(2016)

Getting into hot water: sick guppies frequent warmer thermal conditions,

in Oecologia

181

(3)

pp. 911–917

Full Text UEA Repository

(Article)

(Published)


Aniceto, A. S., Carroll, J., Tetley, M. J., Van Oosterhout, C.

(2016)

Position, swimming direction and group size of fin whales (Balaenoptera physalus) in the presence of a fast-ferry in the Bay of Biscay,

in Oceanologia

58

(3)

pp. 235–240

Full Text UEA Repository

(Article)

(Published)


Smallbone, W., van Oosterhout, C., Cable, J.

(2016)

The effects of inbreeding on disease susceptibility: Gyrodactylus turnbulli infection of guppies, Poecilia reticulata,

in Experimental Parasitology

167

pp. 32-37

Full Text UEA Repository

(Article)

(Published)


Gilroy, D. L., Van Oosterhout, C., Komdeur, J., Richardson, D. S.

(2016)

Toll-like receptor variation in the bottlenecked population of the endangered Seychelles warbler,

in Animal Conservation

Full Text UEA Repository

(Article)

(Published)


Li, J., Cocker, J. M., Wright, J., Webster, M. A., McMullan, M., Dyer, S., Swarbreck, D., Caccamo, M., van Oosterhout, C., Gilmartin, P. M.

(2016)

Genetic architecture and evolution of the S locus supergene in Primula vulgaris,

in Nature Plants

2

article no. 16188

Full Text UEA Repository

(Article)

(Published)


Lighten, J., Incarnato, D., Ward, B. J., van Oosterhout, C., Bradbury, I., Hanson, M., Bentzen, P.

(2016)

Adaptive phenotypic response to climate enabled by epigenetics in a K-strategy species, the fish Leucoraja ocellata (Rajidae),

in Royal Society Open Science

3

article no. 160299

Full Text UEA Repository

(Article)

(Published)


Stephenson, J. F., Van Oosterhout, C., Mohammed, R. S., Cable, J.

(2015)

Parasites of Trinidadian guppies: evidence for sex- and age-specific trait-mediated indirect effects of predators,

in Ecology

96

(2)

pp. 489-498

Full Text UEA Repository

(Article)

(Published)


Simon, A., Gozlan, R. E., Robert Britton, J., Van Oosterhout, C., Hänfling, B.

(2015)

Human induced stepping-stone colonisation of an admixed founder population: the spread of topmouth gudgeon (Pseudorasbora parva) in Europe,

in Aquatic Sciences

77

(1)

pp. 17-25

Full Text UEA Repository

(Article)

(Published)


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Key Research Interests

  1. Evolution and population genetics of birds, fish, insects, plants, fungi and oomycetes. 
  2. The effects of recombination, hybridisation and introgression in evolutionary genetics and genomics.
  3. Population genetics and evolution of the vertebrate immune genes, the MHC
  4. Design of population genetic software for the analysis of microsatellite loci: Micro-Checker (www.microchecker.hull.ac.uk/)
  5. Design of genome analysis software for the detection of recombination: Hybrid-Check (www.norwichresearchpark.com/HybRIDS)
  6. Host-parasite coevolution and the design of individual based models to investigate parasite transmission biology: Gyro-Scope (www.hull.ac.uk/gyro-scope/)

 

Publications: EPrints Digital Repository

Teaching Interests

I am particularlly interested in supervising UG, MSc and PhD students who have an affinity for computational modelling, scripting and/or bioinformatics, and who would like to use and improve their skills to address questions in evolutionary genetic and population genetic research.

I am the module organiser or the MSc module "ENV-MA72: Ecological Modelling and Statistics" in which students acquire basic programming skills (in R) and get training in general and generalised linear statistical modelling and community analysis.

I teach in the 3rd year / MSc module "BIO-6008B: Evolutionary Biology and Conservation Genetics" in which we address the biological applications of molecular genetic markers from the perspective of conservation biology, population biology, organismal phylogeny, molecular ecology and genomics.

In collaboration with Joanne Cable of Cardiff University I also supervise every year a small number of undergraduate and postgraduate research projects in Marine Biology in Tobago.

Key Responsibilities

  • Deputy Director of the Earth and Life Systems Alliance (ELSA) 
  • Co-Director of the International Masters in Applied Ecology (IMAE)