The module deals with signal transduction mechanisms, particularly in mammalian cells and with emphasis on human disease. Topics include the molecular basis of cell surface receptor activation, G-protein coupled receptors, kinases/phosphatases, 2nd messengers such as calcium and inositol lipids, and ion channels. The module then goes on to consider signalling mechanisms important for cell growth, differentiation and survival. (With the agreement of the module organiser, students who have taken BIO-2B01 but not BIO-2B06 may be allowed to take this module.)