The module provides an introduction to the principles of molecular biology. The programme starts with the structure of DNA, genes and genomes, followed by the characterisation of the information flow including the mechanisms and regulation of transcription and translation. Protein folding, modification and turnover are described together with reactions concerning DNA (replication, recombination and repair). The module ends with a detailed description of methods used for the experimental manipulation of genetic material (gene isolation, DNA sequencing, polymerase chain reaction, molecular cloning, transgenic plants and animals and global functional genomics). Practical work includes an introduction to molecular biology techniques together with computer assisted DNA and protein sequence analysis.