Biography

ResearcherID profile

Click here for current PhD opportunities in the School of Biological Sciences.
Click here for current PhD opportunities in the School of Chemistry.
Feel free to email me to discuss projects outside these areas and alternative sources of funding.

Julea Butt is Professor of Biophysical Chemistry at UEA and a Royal Society Leverhulme Trust Senior Research Fellow. Her research elucidates properties of electron transfer proteins relevant to their roles within living organisms. A range of methods are employed, from molecular biology through to biophysical characterisation with a focus on the application of voltammetric, potentiometric and spectroscopic methods. Previously, Julea pioneered the study of adsorbed electroactive proteins for novel perspectives of their biochemistry with Fraser Armstrong (University of Oxford). This approach, adopted by groups around the world, has become known as protein-film electrochemistry (PFE) and Julea received the inaugural Young Investigator Medal from the British Biophysical Society in recognition of her contributions in this area.

Julea’s present research is inspired by the role of electricity, a flow of electrons, in living organisms. Electricity is essential to life because it underpins mechanisms used to harness energy from nutrients and from sunlight and that subsequently drive the synthesis of biomolecules. As a consequence Julea’s research addresses electron transfer by proteins relevant to aspects of human health, microbial infection and the global cycling of iron, nitrogen and sulphur. A recent initiative involves exploring membrane-spanning electron transfer proteins to facilitate the production of solar-fuels and valuable chemicals. Her research, enhanced by collaboration with researchers across the UK and internationally, has been supported by a variety of sponsors including the UK Biotechnology and Biological Sciences Research Council (BBSRC), the UK Engineering and Physical Sciences Research Council (EPSRC), the Wellcome Trust and the US Department of Energy.

Julea contributes to teaching in the Schools of Chemistry and Biological Sciences through lectures, seminars and laboratory classes with a focus on topics in biochemistry, reaction kinetics, spectroscopy, electrochemistry and protein structure. She was Deputy Head of the School of Chemistry (2011-2015), Associate Dean for Post-Graduate Research in the Faculty of Science (2011-2014), Director of the Biochemistry Degree Programmes (2006-2011) and a member of the team that launched the School of Pharmacy at UEA.

Recent Publications

A decaheme cytochrome as a molecular electron conduit in dye-sensitized photoanodes.
Hwang, E T., Sheikh, K., Orchard K., Hojo, D., Radu, V., Lee, C-Y., Ainsworth, E., Lockwood, C., Gross, M., Adschiri, T., Reisner, E., Butt, J., Jeuken, L.
Advanced Functional Materials, 2015, 25 (15) pp 2308-2315
DOI: 10.1002/adfm.201404541

Resolution of key roles for the distal pocket histidine in cytochrome c nitrite reductases.
Lockwood, C., Burlat, B., Cheesman, M., Kern, M., Simon, J., Clarke, T., Richardson, D., Butt, J.
J. Am. Chem. Soc., 2015, 137 (8), pp 3059–3068

Multi-heme cytochromes in Shewanella oneidensis MR-1: Structures, functions and opportunities.
Breuer, M., Rosso, K., Blumberger, J., Butt, J.
Journal of the Royal Society Interface, 2014
DOI: 10.1098/rsif.2014.1117

Explorations of time and electrochemical potential: opportunities for fresh perspectives on signalling proteins.
Butt, J.
Biochemical Society Transactions, 2014, 42, pp47-51

Structural basis of biological NO generation by octaheme oxidoreductases.
Maalcke, W., Dietl, A., Marritt, S., Butt, J., Jetten, M., Keltjens, J., Barends, T., Kartal, B.
Journal of Biological Chemistry, 2014, 289: pp 1228-1242

 

Career History

  • Royal Society Leverhulme Trust Senior Research Fellow 09/2015 - present
  • Professor of Biophysical Chemistry, University of East Anglia 09/2010 - present
  • Reader, University of East Anglia 09/2004 to 08/2010
  • Lecturer, University of East Anglia 09/2001 to 08/2004
  • Wellcome Trust Career Development Fellow, University of East Anglia 09/1997 to 08/2001
  • Post Doctoral Research Fellow, University of Wageningen, NL 05/1995 to 07/1997
  • Post Doctoral Research Fellow, National Institutes of Health, USA 09/1993 to 03/1995
  • PhD, University of California Irvine, USA 1993
  • BA Natural Science - Chemistry, First Class Honours with Distinction in Quantum Mechanics, University of Oxford, 1989

All Publications

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Heath, G. R., Li, M., Polignano, I. L., Richens, J., Catucci, G., O'Shea, P., Sadeghi, S. J., Gilardi, G., Butt, J., Jeuken, L. J. C.

(2016)

Layer-by-Layer Assembly of Supported Lipid Bilayer Poly-l-Lysine Multilayers

in Biomacromolecules

17.

pp. 324-335

Full Text UEA Repository

(Article)


White, G., Edwards, M., Gomez Perez, L., Richardson, D., Butt, J., Clarke, T.

(2016)

Mechanisms of Bacterial Extracellular Electron Exchange.

Elsevier

ISBN 978-0-12-804823-8

Full Text UEA Repository

(Chapter)


Lee, C., Reuillard, B., Sokol, K., Laftsoglou, T., Lockwood, C., Rowe, S., Hwang, E. T., Fontecilla-Camps, J., Jeuken, L., Butt, J., Reisner, E.

(2016)

A decahaem cytochrome as an electron conduit in protein-enzyme redox processes

in Chemical Communications

52.

pp. 7390-7390

Full Text UEA Repository

(Article)


Maalcke, W. J., Reimann, J., de Vries, S., Butt, J. N., Dietl, A., Kip, N., Mersdorf, U., Barends, T. R. M., Jetten, M. S. M., Keltjens, J. T., Kartal, B.

(2016)

Characterization of anammox hydrazine dehydrogenase, a key N

in Journal of Biological Chemistry

291.

pp. 17077-17092

Full Text UEA Repository

(Article)


Breuer, M., Rosso, K., Blumberger, J., Butt, J.

(2015)

Multi-heme Cytochromes in Shewanella oneidensis MR-1: Structures, functions and opportunities

in Journal of The Royal Society Interface

12.

Full Text UEA Repository

(Article)


Lockwood, C., Burlat, B., Cheesman, M., Kern, M., Simon, J., Clarke, T., Richardson, D., Butt, J.

(2015)

Resolution of Key Roles for the Distal Pocket Histidine in Cytochrome c Nitrite Reductases

in Journal of the American Chemical Society

137.

pp. 3059–3068

Full Text UEA Repository

(Article)


Hwang, E. T., Sheikh, K., Orchard, K., Hojo, D., Radu, V., Lee, C., Ainsworth, E., Lockwood, C., Gross, M., Adschiri, T., Reisner, E., Butt, J., Jeuken, L. J. C.

(2015)

A Decaheme Cytochrome as a Molecular Electron Conduit in Dye-Sensitized Photoanodes

in Advanced Functional Materials

25.

pp. 2308–2315

Full Text UEA Repository

(Article)


Beckwith, C., Edwards, M., Lawes, M., Shi, L., Butt, J., Richardson, D., Clarke, T.

(2015)

Characterisation of MtoD from Sideroxydans lithotrophicus: a cytochrome c electron shuttle used in lithoautotrophic growth

in Frontiers in Microbiology

6.

Full Text UEA Repository

(Article)


Pergolizzi, G., Cominetti, M., Butt, J. N., Field, R. A., Bowater, R., Wagner, G. K.

(2015)

Base-modified NAD and AMP derivatives and their activity against bacterial DNA ligases

in Organic & Biomolecular Chemistry

13.

pp. 6380-6398

Full Text UEA Repository

(Article)


Edwards, M., White, G., Norman, M., Tome-Fernandez, A., Ainsworth, E., Shi, L., Fredrickson, J., Zachara, J., Butt, J., Richardson, D., Clarke, T.

(2015)

Redox Linked Flavin Sites in Extracellular Decaheme Proteins Involved in Microbe-Mineral Electron Transfer

in Scientific Reports

5.

Full Text UEA Repository

(Article)


Butt, J., Gates, A., Marritt, S., Richardson, D.

(2015)

Enzyme Film Electrochemistry

Wiley-Blackwell

pp. 105-120

ISBN 978-0-470-57845-2

(Chapter (peer-reviewed))


Kurth, J. M., Dahl, C., Butt, J. N.

(2015)

Catalytic Protein Film Electrochemistry Provides a Direct Measure of the Tetrathionate/Thiosulfate Reduction Potential

in Journal of the American Chemical Society

137.

pp. 13232–13235

Full Text UEA Repository

(Article)


Maalcke, W. J., Dietl, A., Marritt, S. J., Butt, J. N., Jetten, M. S. M., Keltjens, J. T., Barends, T. R. M., Kartal, B.

(2014)

Structural basis of biological NO generation by octaheme oxidoreductases

in Journal of Biological Chemistry

289.

pp. 1228-1242

Full Text UEA Repository

(Article)


Edwards, M. J., Baiden, N., Johs, A., Tomanicek, S. J., Liang, L., Shi, L., Fredrickson, J. K., Zachara, J. M., Gates, A. J., Butt, J. N., Richardson, D. J., Clarke, T. A.

(2014)

The X-ray crystal structure of Shewanella oneidensis OmcA reveals new insight at the microbe-mineral interface

in FEBS Letters

588.

pp. 1886-1890

Full Text UEA Repository

(Article)


Butt, J.

(2014)

Explorations of time and electrochemical potential: opportunities for fresh perspectives on signalling proteins

in Biochemical Society Transactions

42.

pp. 47-51

Full Text UEA Repository

(Article)


Liu, Y., Wang, Z., Liu, J., Levar, C., Edwards, M., Babauta, J., Kennedy, D., Shi, Z., Bayenal, H., Bond, D. R., Clarke, T., Butt, J., Richardson, D., Rosso, K., Zachara, J., Fredrickson, J., Shi, L.

(2014)

A trans-outer membrane porin-cytochrome protein complex for extracellular electron transfer by Geobacter sulfurreducens PCA

in Environmental Microbiology Reports

6.

pp. 776-785

Full Text UEA Repository

(Article)


White, G., Shi, Z., Shi, L., Wang, Z., Dohnalkova, A. C., Marshall, M. J., Fredrickson, J. K., Zachara, J. M., Butt, J., Richardson, D., Clarke, T., cytochrome, mineral respiration

(2013)

Rapid electron exchange between surface-exposed bacterial cytochromes and Fe(III) minerals.

in Proceedings of the National Academy of Sciences of the United States of America (PNAS)

110.

pp. 6346-6351

Full Text UEA Repository

(Article)


Richardson, D., Butt, J., Clarke, T.

(2013)

Controlling electron transfer at the microbe-mineral interface

in Proceedings of the National Academy of Sciences of the United States of America (PNAS)

110.

pp. 7537-7538

Full Text UEA Repository

(Article)


Doyle, R., Marritt, S., Gwyer, J., Lowe, T., Cheesman, M., Butt, J., Tikhonova, T., Popov, V.

(2013)

Contrasting catalytic profiles of multiheme nitrite reductases containing CxxCK heme-binding motifs

in JBIC Journal of Biological Inorganic Chemistry

18.

pp. 655-667

Full Text UEA Repository

(Article)


<- Page 1 of 5 ->

Key Research Interests

Julea Butt’s research focuses on redox proteins. Her research group aims to provide greater insight into the cellular roles of these proteins and as a consequence inform their exploitation in biotechnologies.

Some new and long-standing research programmes pursued in collaboration with researchers within the UK and internationally are outlined below:

  • Advancing Biotechnologies for Solar-Microbial Fuel Generation
  • Microbial Mineral Respiration
  • Enzymology of the Nitrogen Cycle
  • Fresh Approaches to Spectroelectrochemistry and the Application of Protein Film Voltammetry

We welcome discussions on opportunities to extend our collaborations to study additional systems.

Enquiries are always welcome from potential PhD students. We would be particularly keen to recruit someone to study novel cytochromes from Anammox bacteria and bacterial nanowire proteins from Shewanella. However, we will seriously consider applicants wanting to work in any one of our areas of interest. Feel free to e-mail Julea (j.butt@uea.ac.uk) if you would like to discuss these opportunities and possible funding opportunities.

 

Advancing Biotechnologies for Solar-Microbial Fuel Generation

Many renewable energy supplies, such as sunlight, remain largely untapped resources due to the challenges that exist in converting these energy forms into fuels from which energy can be released on demand. During natural plant photosynthesis, fuels are made from the energy in sunlight. Light is absorbed by the green chlorophyll pigments to generate an energised electron that is directed, along chains of metal centres, to catalysts that produce sugars. Taking inspiration from such processes, we are seeking to develop synthetic biology that will allow for artificial photosynthesis in the bacterium Shewanella oneidensis MR-1.

Read more on page 14 of the UEA 50Th Anniversary Souvenir Magazine 

Collaborators: David J. Richardson and Tom Clarke (UEA), Erwin Reisner (Cambridge), Lars Jeuken (Leeds), Jim Fredrickson and Liang Shi (Pacific Northwest National Laboratory, USA).

Microbial Mineral Respiration

There is much interest in ‘rock-breathing’ bacteria. The mechanism by which these microbes couple the generation of a proton-motive force across the cytoplasmic membrane to the reduction of minerals, located outside the cell, has yet to be fully elucidated. From a biotechnological perspective, it is of interest to understand how best to substitute extra-cellular minerals with electrodes for effective utilisation of these bacteria such as Shewanella species in mediatorless microbial fuel cells. Protein film voltammetry (see below) is being complemented with contemporary biochemistry to study multi-heme cytochromes key to the respiratory reduction of extracellular mineral oxides and electrodes by Shewanella oneidensis MR-1.

View the lecture on Multi-heme cytochromes here.

Collaborators: David J. Richardson and Tom Clarke (UEA), Lars Jeuken (University of Leeds), Jim Fredrickson and Liang Shi (Pacific Northwest National Laboratory, USE).

Highlight Publications:
Rapid electron exchange between surface-exposed bacterial cytochromes and Fe(III) minerals.
Proc. Nat.
Acad. Sci. USA, 2013, 110:6346-6351.
DOI: 10.1073/pnas.1220074110

Protein–Protein Interaction Regulates the Direction of Catalysis and Electron Transfer in a Redox Enzyme Complex.
J. Am. Chem. Soc., 2013 135:10550-10556. 

Characterization of Shewanella oneidensis MtrC: a cell-surface decaheme cytochrome involved in respiratory transport to extracellular electron acceptors
J. Biol. Inorg.Chem., 2007 12:1083-1094

 

Enzymology of the Nitrogen Cycle

Microbes exploit redox transformations of inorganic nitrogen species to support aerobic and anaerobic respiration, to allow nitrogen assimilation into amino acids and nucleotides and to defend against cytotoxins such as nitric oxide. Protein film voltammetry has resolved the windows of electrochemical potential over which enzymes reducing nitrate, nitrite, nitric oxide and/or hydroxylamine are active. Present research aims to understand the origin of these properties at the molecular level and their contribution to cellular function by site specific protein engineering, spectroscopy and cellular studies.

Collaborators: David J. Richardson and Tom Clarke (UEA), Tamara Tikhonova and Vladimir Popov (Moscow, Russia)

Highlight Publications:
Structural Basis of Biological NO Generation by Octaheme Oxidoreductases.
J. Biol. Chem., 2014, 289, 1228-1242.
DOI: 10.1074/jbc.M113.525147

Contrasting Catalytic Profiles of Multiheme Nitrite Reductases Containing CxxCK Heme-Binding motifs.
J. Biol. Inorg. Chem. 2013 18:655-667.
DOI: 10.1007/s00775-013-1011-7

The Nitric Oxide Reductase Activity of Cytochrome c Nitrite Reductase from Escherichia coli.
J. Biol. Chem. 2008 283:9587-9594. 
DOI:

 

Fresh Approaches to Spectroelectrochemistry and the Application of Protein Film Voltammetry

Dynamic electrochemistry provides a powerful tool to characterise redox proteins and enzymes. Electron transfer and any associated chemical events are visualised in real-time by the flow of electrical current observed when electrons are exchanged between a protein and an electrode of known and variable potential. In particular, protein film electrochemistry allows the measurement of both thermodynamic (redox potentials and affinities for protons and/or other ligands) and kinetic (steady-state catalysis) properties. In this technique, the protein of interest is adsorbed as an electro-active monolayer film on an electrode surface. Collaborations with multiple research groups have led to the development of electrochemistry performed in parallel with electronic absorbance, Fourier transform infrared spectroscopy, and magnetic circular dichroism to provide simultaneous chemical insight into the redox driven events.

Collaborators: Myles Cheesman (UEA), Ben Berks (Oxford), Mike Wilson and Jonathan Worrall (Essex).

Highlight Publications:
Redox and Chemical Activities of the Hemes in the Sulfur Oxidation Pathway Enzyme SoxAX.
J. Biol. Chem.
2012, 287:40350-40359
DOI:

A Functional Description of CymA, an Electron-Transfer Hub Supporting Anaerobic Respiratory Flexibility in Shewanella.
Biochem. J.  2012, 444:465-474.
DOI: 10.1042/BJ20120197

Probing a Complex of Cytochrome c and Cardiolipin by Magnetic Circular Dichroism Spectroscopy: Implications for the Initial Events in Apoptosis.
J. Am. Chem. Soc. 2011, 133:19676-19679.
DOI: 10.1021/ja209144h

Research Funding

EPSRC:  Characterisation of electron transport in bacterial nano-wire proteins through high performance computing and experimentation
PIs: Butt and Blumberger (UCL), CoIs Clarke, Meech and Watmough (UEA).
26/1/2015-25/1/2018
£750k
 
BBSRC:  Advancing microbial electrochemistry: biophysical characterisation of the electron-transfer interactome in S. oneidensis MR-1
PIs: Butt & Jeuken (Leeds), CoIs Richardson, Clarke and Cheesman (UEA), Evans (Leeds).
1/11/2014 – 30/10/2017
£800k

BBSRC: The molecular interface of microbe-mineral electron transfer.
PI: Richardson (UEA), CoIs Butt, Clarke and Gates (UEA).
1/11/2014 – 30/10/2017
£350k

BBSRC Adding Value to Galactomannan Polysaccharides with Cu-Enzymes
PI: Butt
1/11/2015 – 1/6/2015)
£5k  (NIBB: Business Interaction Voucher)

BBSRC: Advancing Biotechnologies for Fuel Generation: Exploiting Transmembrane Cytochromes for Solar Energy Conversion
PI: Julea Butt. CoI: David Richardson, Tom Clarke
1/1/2013 – 31/12/2015
£380k

BBSRC: Molecular Basis for Controlled Transmembrane Electron Transfer
PI: Tom Clarke. CoI: David Richardson, Julea Butt
1/1/2013 – 31/12/2015
£321k

BBSRC iCASE PhD Studentship: Carbon Capture and Formate Biosynthesis using a Microbe-Electrode Device
PI: Tom Clarke. CoI: Julea Butt
10/2013 – 9/2016

US Dept of Energy: Characterisation of Cytochromes key to ExtraCellular Mineral Respiration
PI: David Richardson. Col: Julea Butt, Tom Clarke
1/10/2013 – 30/9/2015
£150k

United States Department of Energy
The Structural and Mechanistic Basis of Microbial Mineral Respiration
Richardson DJ, Butt JN, Clarke, TA
01-Oct-10 to 31-Sep-14
$800,000

BBSRC
Correlating currents and colour in metalloenzymes. Cell development for time and concentration resolved magnetic-CD spectroscopy.
Cheesman MR, Butt JN
01-Jul-09 – 31-Dec-10
£96,941

BBSRC
New approaches for fresh perspectives on quinol/quinone oxidoreductases.
Butt JN, Richardson DJ, Jeuken (Leeds), Evans (Leeds)
01-Jun-09 - 30-May-12
£339,576

BBSRC

The contribution of ammonification to N2O emissions from soils
Richardson, DJ, Butt, JN, Baggs, E (Aberdeen)
01-Feb-06 – 31-Jan-09
£175,132

Leverhulme Trust
Regulating electron transport to functional synthetic redox-active metal sites
Mareque Rivas, JC, (Edinburgh), Yellowlees, LJ, (Edinburgh), Butt, JN
01-Sep-05 – 31-Aug-08
£101,317

BBSRC
The molecular enzymology of nitric oxide reductase: cellular saviour and global bandit
Watmough, NJ, Butt, JN, Cheesman, MR and Richardson, DJ
01-Sep-05 - 31-Aug-08
£221,432

BBSRC
Mottle-MCD Spectroscopy with in situ electrochemical control
Butt, JN, Cheesman, MR and Durrant, J (Imperial)
01-Aug-05 - 31-Jul-08
£146,297

BBSRC
BMS Committee Studentship
Butt, JN
01-Oct-03 - 30-Sep-07
Studentship

BBSRC
The cytochrome c nitrite reductase: an integrated study of nitrite and nitric oxide reduction by a deca-heme enzyme complex
Richardson, DJ, Butt, JN, Cheesman, MR, Hemmings, AM and Cole, J (Birmingham)
20-Oct-03 - 19-Jul-07
£354,500

Royal Society of Chemistry
A new concept for the assay of DNA ligases - facilitating studies of a potential new drug target
Butt, JN and Bowater, RP
01-Oct-03 - 30-Sep-06
£44,055

Wellcome Trust
DNA ligase - one or many?
Butt, JN
28-Jun-06 - 20-Aug-06
£1,360

Nuffield Foundation
Resolving the chemistry of nitrate reduction, an essential part of the global nitrogen economy
Butt, JN
26-Jun-06 - 14-Aug-06
£1,310

UEA/IPDF
Immobilised oligonucleotide hairpins for rapid assessment of ligase and nuclease activities.
Bowater, RJ and Butt JN
06-Feb-06 – 06-Aug-06
£4,782

Wellcome Trust
JIF: Biophysical chemistry at UEA
Thomson, AJ, Butt, JN, Le Brun, NE, Kleanthous, CK (York), Richardson, DJ, Watmough, NJ, Cheesman, MR and Moore, G
01-Jun-01 - 30-Jun-06
£3,451,823

BBSRC
An integrated approach to define the mechanism of respiratory nitrate reductase: Spectroscopic and voltammetric studies
Butt, JN and Richardson, DJ
29-Jul-02 - 28-Feb-06
£181,928

BBSRC
Structure-function studies of a novel haemoprotein involved in bacterial oxidation of thiosulfate & sulfide
Hemmings, AM, Butt, JN, Cheesman, MR and Berks, B (Oxford)
01-Jan-02 - 30-Apr-05
£42,300

BBSRC
Interrogating DNA duplex-ligand interactions: A dynamic approach exploiting the intrinsic conductivity of duplex DNA
Butt, JN, Mayes, AG and Bowater, RP
12-Aug-02 - 11-Feb-05
£165,633

BBSRC
Steady state kinetic studies of electron transfer flavoprotein ubiquinone oxidoreductase
Watmough, NJ and Butt, JN
19-Jul-04 - 05-Sep-04
£1,700

EPSRC
(a) Muon Spectroscopies as a probe of electron conduction in DNA, and (b) Muon spectroscopy of organometallics
Jayasooriya, UA and Butt, JN
08-Aug-01 - 07-Nov-02
£16,484

Wellcome Trust
Time resolved studies of redox driven events in membrane bound proteins under the direct potential control of an electrode
Butt, JN
01-Sep-97 - 31-Oct-01
£26,000

Royal Society of Chemistry
Development of a sensitive and selective direct electrochemical sensor for DNA with potential application in parallel genomics
Thomson, A J and Butt, JN
01-Oct-98 - 30-Sep-01
£32,000

Wellcome Trust
Research career development fellowship
Butt, J N and Thomson, A J
01-Sep-97 - 15-Mar-01
£280,646 

 

PhD Positions

Click here for current PhD opportunities in the School of Biological Sciences.

Click here for current PhD opportunities in the School of Chemistry.

But feel free to email me to discuss projects outside these areas and alternative sources of funding.

 

Research Group Membership

PhD Students
Emma Ainsworth
Leon Jenner
David Miko
Sam Rowe

Post-Doctoral Research Associates
Tony Blake
Colin Lockwood
Jessica van Wonderen
Technician
Simone Payne

Project Students
Jack Day
Jack McLeish

External Activities and Indicators of Esteem

Recent Invited Lectures Include:

Multiheme Cytochromes as Electron Transfer Conduits in Bioenergy Applications: Insights from Shewanella oneidensis MR-1. Fourth International Symposium on Energy Challenges and Mechanics: Working on Small Scales.
Aberdeen, UK. Aug 2015.

Multiheme Cytochromes of Shewanella oneidensis: The Molecular Basis of Electron Exchange between Bacteria and Electrodes or Mineral Oxide Particles.
Plenary Lecture: XXIII International Symposium on Bioelectrochemistry and Bioenergetics.
Malmö, Sweden. June 2015.

A Bright Future for Multi-Tasking Enzymes?
Microbes in Norwich. Norwich, UK. Jan 2015.

Microbes, Minerals and Biotechnology: The Versatile Respiratory Machinery of Shewanella oneidensis MR-1.
Interface between Experimental and Theoretical Approaches to Energy-Related Enzyme Catalysis. London, UK. June 2014

Rock-Breathing Bacteria: Inspiring Sustainable Energy Solutions.
Campus in the City. Norwich, UK. May 2014.

Explorations of Time and Electrochemical Potential: Opportunities for Fresh Perspectives on Signalling Proteins.
Signalling 2013: From Structure to Function. York, UK. July 2013.

Microbes, minerals and biotechnology: the versatile respiratory machinery of Shewanella oneidensis MR-1.
Bioenergetics in Mitochondria, Bacteria and Chloroplasts. Ebsdorfergrund, Germany. April 2013.

Resolving the Heart of the Action - Spectroelectrochemical Studies of Cytochromes.
KeyNote Speaker: 63rd Annual Meeting of the International Society of Electrochemistry.
Prague, Czech Republic. August 2012.

Revealing the Redox Chemistry and Substrate-Specificity of a Quinol-Dehydrogenase.
45th Heyrovsky Discussion: Brno, Czech Republic. August 2012.

Multiheme Cytochromes - Molecular Wires and Catalysts
Electron transfer at the microbe-mineral interface: Biochemical Society Meeting. Norwich, UK. April 2012.

Contrasting Properties of Octa- and Penta-Heme Nitrite Reductases.
16th European N-cycle Meeting and ICoN2, Nijmegen, Netherlands. July 2011.

Defining a Landscape for Microbial Electron Transfer to Extracellular Minerals.
Goldschmidt 2011, Prague, Czech Republic. August 2011.

Professional Affiliations Include Membership of:

  • Biochemical Society
  • British Biophysical Society
  • Inorganic Chemistry Discussion Group of the Royal Society of Chemistry
  • Royal Society of Chemistry 
  • The American Chemical Society

Key Responsibilities

  • Professor of Biophysical Chemistry
  • Royal Society Leverhulme Trust Senior Research Fellow