Synthetic Chemistry

Synthetic chemistry within the School covers methodology, biological and medicinal target molecule synthesis, synthesis of functional materials, organometallics and polymerisation catalysts. There are strong collaborations with members of the other two Chemistry themes within the School.

Research is currently led by the following members of Faculty:

	Dr Sean Bew N-Chloroamines for nitrogen activation and N-alkylaziridine synthesis Expedient synthesis of N-alkylaziridines using (S)-N-(α-methylbenzyl)hydroxylamines Organocatalytic imine activation for N-alkylaziridine synthesis Synthesis of a new class of upper-rim appended bifunctional calix[4]arenes α-Amino acids as tethers for diastereoselective HIMDA reactions Tröger base as a peptidemimetic Chemical Genetics
	Prof Manfred Bochmann organometallic and coordination chemistry directed towards homogeneous catalysis; polymerisation catalysis with well-defined soluble catalysts; solution structures; chemistry of non-coordinating anions precursors for semiconductor quantum dots
	Prof Andrew N. Cammidge Organic Synthesis Molecular materials and liquid crystals Cross-coupling catalysis
	Prof Michael J. Cook Phthalocyanines Materials chemistry Thin films
	Dr Rebecca Goss Elucidating biosynthetic pathways (the Goss group have recently been the first to discover the genes encoding a uridyl peptide: Pacidamycin Biosynthesis: Identification and Heterologous Expression of the First Uridyl Peptide Antibiotic Gene Cluster) Developing biotransformations for use in synthetic chemistry Harnessing biosynthetic pathways to enable libraries of designer “natural” products to be accessed rapidly. (The Goss group’s have pioneered a new concept “Chemogenetics” for the generation of Natural Product analogues: *Gene expression enabling synthetic diversification of unnatural products:chemogenetic generation pacidamycin analogs)(Abhijeet Deb Roy, Sabine Grüschow, Nickiwe Cairns, Rebecca J. M. Goss, J. Am. Chem. Soc., 2010, Article ASAP. DOI: 10.1021/ja1060406. Was highlighted in C.&EN. News, August 23rd, 2010)**
	Dr Simon J. Lancaster Metal-organics in materials and catalysis Supramolecular organometallic chemistry Small molecule activation Novel multiple bonds
	Dr Maria Paz Muñoz Herranz New Transition Metal-Catalysed Reactions of allenes. Total Synthesis and Byosynthesis of allenic natural products with potential biological activity. Studies on the stereochemistry of addition on the triflic acid-promoted lactonisation of allyl malonates.
	Dr Carl Redshaw Synthesis, structural and catalytic activity of metallocalixarenes The chemistry and catalytic properties of organoaluminium systems The use of metal agents against Cancer/Leukaemia
	Dr G. Richard Stephenson Metal-mediated organic synthesis Helicene-based chiral pi systems for nonlinear optics Carbonylmetal complexes as bioprobes
	Prof Phil Page Total synthesis of natural products Asymmetric synthesis and catalysis Organocatalysis
	Dr Chris Richards Stereoselective organometallic chemistry Asymmetric catalysis Synthesis of bioactive compounds
	Dr Gregory G. Wildgoose Organometallic synthesis & electrochemistry Electrocatalysis Energy & Materials Electrochemical Nanoscience & Nanomaterials Analytical Chemistry Sensors and Catalysts

Chemistry

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