Article

Belshaw, NJ, Pal, N, Tapp, HS, Dainty, JR, Lewis, MPN, Williams, MR, Lund, EK and Johnson, IT (2010) Patterns of DNA methylation in individual colonic crypts reveal aging and cancer-related field defects in the morphologically normal mucosa. Carcinogenesis, 31 (6). pp. 1158-1163. ISSN 0143-3334

Reynolds, Amy, Parris, Alyson, Evans, L, Lindqvist, Susanne, Sharp, P., Lewis, M., Tighe, R. and Williams, Mark (2007) Dynamic and differential regulation of NKCC1 by calcium and cAMPin the native human colonic epithelium. The Journal of Physiology, 582 (2). pp. 507-524. ISSN 0022-3751

Williams, MR, Spahos, T, Reynolds, A, Parris, A, Tighe, R, Speakman, C, Beales, ILP and Lewis, M (2007) Taurodeoxycholic acid induces calcium oscillations in isolated human colonic crypts. Gastroenterology, 132 (Suppl 2). p. 8.

Parris, Alyson, Reynolds, Amy, Spahos, A., Munsterberg, Andrea, Tighe, R., Lewis, M., Cook, J., Prior, A., Speakman, C., Stebbings,, Hernon, J., Beales, Ian, Ellamin, K. and Williams, Mark (2006) Human colonic crypt renewal ex vivo. Gastroenterology, 130 (Suppl 2). p. 1677.

Parris, A, Reynolds, A, Spahos, T and Williams, M (2005) Wnt signalling mobilises beta-catenin and stimulates cell proliferation in isolated human colonic crypts. Gastroenterology, 128 (4). p. 489.

Reynolds, Amy, Addison, S., Lindqvist, Susanne and Williams, Mark (2005) Propagating calcium signals along human colonic crypts dynamically regulate NKCC1 phosphorylation and activity. Gastroenterology, 128. pp. 357-358.

Parris, A, Reynolds, A, Addison, S, Lindqvist, S, Hernon, J, Spahos, T, Tighe, T, Lewis, M, Mackay, J, Westgarth, D, Fellows, F, Bell, D, Kapur, S, Prior, A and Williams, M (2004) Spatial correlation between acetylcholine-induced calcium signals and acetylcholine-induced cell proliferation along the isolated human colonic crypt axis. Gastroenterology, 126. p. 140.

Addison, S., Lindqvist, Susanne, Setchell, O., Hernon, J., Tighe, R., Rhodes, M., Stebbings, W. and Williams, Mark (2003) Top-down aberrant calcium signals in colonic crypts derived from the flat mucosa of polyp- and colorectal cancer-patients. Gastroenterology, 124 (4, Supplement 1). A282.

Addison, S., Lindqvist, Susanne, Setchell, O., Hernon, J., Tighe, R., Mackay, J., Rhodes, M., Stebbings, W. and Williams, Mark (2003) Prostaglandin E2 induces calcium signals in the proliferative zone of isolated human colonic crypts. Gastroenterology, 124 (4). A276-A276. ISSN 00165085

Hernon, JM, Lindqvist, SM, Prior, A and Williams, MR (2003) Carbachol induces ERK 1/2 activation and stimulates cell proliferation via a metalloproteinase- and TGFá dependent pathway. Gastroenterology, 124 (Suppl 1). p. 285.

Olano-Martin, Estibaliz, Williams, Mark, Gibson, Glenn R and Rastall, Robert A (2003) Pectins and pectic-oligosaccharides inhibit Escherichia coliO157:H7 Shiga toxin as directed towards the human colonic cell line HT29. FEMS Microbiology Letters, 218 (1). pp. 101-105. ISSN 03781097

Hernon, JM, Lindqvist, SM, Rhodes, M, Speakman, CTM, Stebbings, WSL and Williams, MR (2002) Acetylcholine stimulates Human Colonic epithelial cell growth via calcium dependent MAP Kinase activation. Colorectal Disease. pp. 4-41.

Hernon, JM, Lindqvist, SM, Rhodes, M, Speakman, CTM, Tighe, R, Murphy, G, Stebbings, WSL and Williams, MR (2002) Molecular mechanisms of acetylcholine-induced ERK1/2 activation in HT29 cells and isolated human colonic crypts. Gastroenterology, 122 (4). p. 991.

Hotchkiss, A.T., Olano-Martin, E., Williams, Mark, Grace, W.E., Gibson, G.R. and Rastall, R.A. (2002) Pectic oligosaccharides as prebiotics. Abstracts of papers of the American Chemical Society, 223. p. 34.

Lindqvist, SM, Hernon, J, Sharp, P, Johns, N, Addison, S, Watson, MJ, Tighe, R, Greer, S, Mackay, J, Rhodes, M, Lewis, M, Stebbings, W, Speakman, C, Evangelista, S, Johnson, I and Williams, MR (2002) The colon-selective spasmolytic otilonium bromide inhibits muscarinic M3 receptor-coupled calcium signals in isolated human colonic crypts. British Journal of Pharmacology, 137 (7). pp. 1134-1142.

Sharp, Paul, Tandy, Sarah, Yamaji, Sachie, Tennant, Jason, Williams, Mark and Singh Srai, Surjit Kaila (2002) Rapid regulation of divalent metal transporter (DMT1) protein but not mRNA expression by non-haem iron in human intestinal Caco-2 cells. FEBS Letters, 510 (1-2). pp. 71-76. ISSN 00145793

Tandy, S., Williams, Mark, Srai, S.K., Yamaji, S., Tennant, J. and Sharp, P. (2002) Reciprocal regulation of DMT1 and transferrin receptor expression during differentiation of Caco-2 cells in culture. Journal of Physiology, 533. p. 13.

Tennant, J., Sharp, P., Tandy, S., Williams, Mark, Yamaji, S. and Srai, S.K. (2002) Effects of dietary metals on the expression of DMT1 in human intestinal Caco-2 cell line. Journal of Physiology, 533. pp. 13-14.

Williams, M. R. and Sharp, P. (2002) Regulation of jejunal glucose transporter expression by forskolin. Biochimica et Biophysica Acta (BBA) - Biomembranes, 1559 (2). pp. 179-185. ISSN 0005-2736

Lindqvist, SM, Hernon, JM, Sharp, PA, Mackay, J, Tighe, R, Rhodes, M and Williams, MR (2001) Calcium-dependent stimulation of the p44/42 mitogen-activated protein kinase pathway by acetylcholine in isolated human colonic crypts. Gastroenterology, 120 (Suppl 1). p. 700.

Williams, M. R., Riach, R.A., Collison, David and Duncan, G. (2001) Role of the endoplasmic reticulum in shaping calcium dynamics in human lens cells. Investigative Ophthalmology and Visual Science, 42 (5). pp. 1009-1017. ISSN 0146-0404

Williams, MR, Lindqvist, SM and Evangelista, S (2001) The colon-selective muscarinic antagonist otilonium bromide inhibits M3 acetylcholine receptors in human colonic crypts. FASEB Journal, 15 (4). p. 558.

Williams, MR, Lindqvist, SM, Hernon, JM, Sharp, P and Johnson, IT (2001) Stimulation of acetylcholine muscarinic receptors activates MAP kinase-dependent cell proliferation in HT29 human colonic epithelial cells via the calcium signaling pathway. Gastroenterology, 120 (Suppl 1). p. 2527.

Yamaji, Sachie, Tennant, Jason, Tandy, Sarah, Williams, Mark, Singh Srai, Surjit Kaila and Sharp, Paul (2001) Zinc regulates the function and expression of the iron transporters DMT1 and IREG1 in human intestinal Caco-2 cells. FEBS Letters, 507 (2). pp. 137-141. ISSN 00145793

Conference or Workshop Item

Scobioala-Laker, N, Reynolds, A, Parris, A, Mitchell, EM, Lewis, M, Kennedy, HJ, Stebbings, W, Prior, A, Phillips, M, Beales, I and Williams, MR (2009) A Novel 3D Ex Vivo Model of Native Human Barrett's Oesophagus. In: Digestive Disease Week/110th Annual Meeting of the American-Gastroenterological-Association, May 30 - Jun 04 2009, Chicago, IL.

Other

Reynolds, A., Parris, A., Tighe, R., Lewis, M., Westgarth, D., Bell, D., Jamieson, C., Dearlymple, J., Southgate, J., Sargen, K. and Williams, Mark (2006) Acetylcholine stimulation of the NKCC1 transporter is calcium-dependent and is rapidly desensitised by endocytosis in human colonic crypts: major implications for intestinal fluid secretion. UNSPECIFIED.